Systematic Evaluation of Chemically Distinct Tissue Optical Clearing Techniques in Murine Lymph Nodes

FDISCO: Advanced solvent-based clearing method for imaging whole organs

(2019) Yisong Qi et al.   Science Advances

Comparative analysis reveals Ce3D as optimal clearing method for in toto imaging of the mouse intestine

(2019) Gleison D. P. Bossolani et al.   NEUROGASTROENTEROLOGY AND MOTILITY

High‐resolution imaging of fluorescent whole mouse brains using stabilised organic media (sDISCO)

(2019) Christian Hahn et al.   Journal of Biophotonics

High-dimensional cell-level analysis of tissues with Ce3D multiplex volume imaging

(2019) Weizhe Li et al.   Nature Protocols

Advances in Ex Situ Tissue Optical Clearing

(2019) Paweł Matryba et al.   Laser & Photonics Reviews

Optical clearing potential of immersion-based agents applied to thick mouse brain sections

(2019) Mathew Loren et al.   PLoS One

Multi-immersion open-top light-sheet microscope for high-throughput imaging of cleared tissues

(2019) Adam K. Glaser et al.   Nature Communications

B cell dissemination patterns during the germinal center reaction revealed by whole-organ imaging

(2019) Liat Stoler-Barak et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Advanced CUBIC tissue clearing for whole-organ cell profiling

(2019) Katsuhiko Matsumoto et al.   Nature Protocols

Hydrogel-Tissue Chemistry: Principles and Applications

(2018) Viviana Gradinaru et al.   Annual Review of Biophysics

Tissue clearing of both hard and soft tissue organs with the PEGASOS method

(2018) Dian Jing et al.   CELL RESEARCH

Comparison of the 3-D patterns of the parasympathetic nervous system in the lung at late developmental stages between mouse and chicken

(2018) Tadayoshi Watanabe et al.   DEVELOPMENTAL BIOLOGY

Expansion microscopy: enabling single cell analysis in intact biological systems

(2018) Shahar Alon et al.   FEBS Journal

Optimized perfusion-based CUBIC protocol for the efficient whole-body clearing and imaging of rat organs

(2018) Paweł Matryba et al.   Journal of Biophotonics

A three-dimensional single-cell-resolution whole-brain atlas using CUBIC-X expansion microscopy and tissue clearing

(2018) Tatsuya C. Murakami et al.   NATURE NEUROSCIENCE

Three-dimensional volume fluorescence-imaging of vascular plasticity in adipose tissues

(2018) Ying Cao et al.   Molecular Metabolism

Whole-body clearing, staining and screening of calcium deposits in the mdx mouse model of Duchenne muscular dystrophy

(2018) Lukasz Bozycki et al.   Skeletal Muscle

Optimization of GFP Fluorescence Preservation by a Modified uDISCO Clearing Protocol

(2018) Yusha Li et al.   Frontiers in Neuroanatomy

Evaluation of seven optical clearing methods in mouse brain

(2018) Peng Wan et al.   Neurophotonics

Quantitative assessment of optical clearing methods in various intact mouse organs

(2018) Jianyi Xu et al.   Journal of Biophotonics

Mechanisms of Tumor-Induced Lymphovascular Niche Formation in Draining Lymph Nodes

(2018) Catharina D. Commerford et al.   Cell Reports

Iterative expansion microscopy

(2017) Jae-Byum Chang et al.   NATURE METHODS

Multiplex, quantitative cellular analysis in large tissue volumes with clearing-enhanced 3D microscopy (Ce3D)

(2017) Weizhe Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lymph Node Stroma Dynamics and Approaches for Their Visualization

(2017) Rebecca Gentek et al.   TRENDS IN IMMUNOLOGY

Interactions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis

(2017) Lalit Kumar Dubey et al.   Nature Communications

Whole-Body Profiling of Cancer Metastasis with Single-Cell Resolution

(2017) Shimpei I. Kubota et al.   Cell Reports

CUBIC pathology: three-dimensional imaging for pathological diagnosis

(2017) Satoshi Nojima et al.   Scientific Reports

Chemical Principles in Tissue Clearing and Staining Protocols for Whole-Body Cell Profiling

(2016) Kazuki Tainaka et al.   Annual Review of Cell and Developmental Biology

Clonal Proliferation and Stochastic Pruning Orchestrate Lymph Node Vasculature Remodeling

(2016) Isabelle Mondor et al.   IMMUNITY

pMHC affinity controls duration of CD8 + T cell–DC interactions and imprints timing of effector differentiation versus expansion

(2016) Aleksandra J. Ozga et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Light sheet fluorescence microscopy for in situ cell interaction analysis in mouse lymph nodes

(2016) Jun Abe et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Shrinkage-mediated imaging of entire organs and organisms using uDISCO

(2016) Chenchen Pan et al.   NATURE METHODS

Lymphotoxin-Dependent B Cell-FRC Crosstalk Promotes De Novo Follicle Formation and Antibody Production following Intestinal Helminth Infection

(2016) Lalit Kumar Dubey et al.   Cell Reports

Super-Resolution Mapping of Neuronal Circuitry With an Index-Optimized Clearing Agent

(2016) Meng-Tsen Ke et al.   Cell Reports

Simplified three-dimensional tissue clearing and incorporation of colorimetric phenotyping

(2016) Kevin Sung et al.   Scientific Reports

Clarifying Tissue Clearing

(2015) Douglas S. Richardson et al.   CELL

Optical clearing based cellular-level 3D visualization of intact lymph node cortex

(2015) Eunjoo Song et al.   Biomedical Optics Express

Scalable and DiI-compatible optical clearance of the mammalian brain

(2015) Bing Hou et al.   Frontiers in Neuroanatomy

Whole-Brain Imaging with Single-Cell Resolution Using Chemical Cocktails and Computational Analysis

(2014) Etsuo A. Susaki et al.   CELL

iDISCO: A Simple, Rapid Method to Immunolabel Large Tissue Samples for Volume Imaging

(2014) Nicolas Renier et al.   CELL

Contextual Analysis of Immunological Response through Whole-Organ Fluorescent Imaging

(2013) Matthew C. Woodruff et al.   Lymphatic Research and Biology

SeeDB: a simple and morphology-preserving optical clearing agent for neuronal circuit reconstruction

(2013) Meng-Tsen Ke et al.   NATURE NEUROSCIENCE

Trapping of naive lymphocytes triggers rapid growth and remodeling of the fibroblast network in reactive murine lymph nodes

(2013) C.-Y. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Three-dimensional imaging of solvent-cleared organs using 3DISCO

(2012) Ali Ertürk et al.   Nature Protocols

Optical projection tomography reveals dynamics of HEV growth after immunization with protein plus CFA and features shared with HEVs in acute autoinflammatory lymphadenopathy

(2012) Varsha Kumar et al.   Frontiers in Immunology

Global lymphoid tissue remodeling during a viral infection is orchestrated by a B cell-lymphotoxin-dependent pathway

(2010) V. Kumar et al.   BLOOD