The novel, orally available and peripherally restricted selective cannabinoid CB2 receptor agonist LEI-101 prevents cisplatin-induced nephrotoxicity

Endocannabinoid signalling in innate and adaptive immunity

(2015) Valerio Chiurchiù et al.   IMMUNOLOGY

Deficiency of cannabinoid receptor of type 2 worsens renal functional and structural abnormalities in streptozotocin-induced diabetic mice

(2014) Federica Barutta et al.   KIDNEY INTERNATIONAL

Overactive cannabinoid 1 receptor in podocytes drives type 2 diabetic nephropathy

(2014) Tony Jourdan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of an Activity-Based Probe and In Silico Design Reveal Highly Selective Inhibitors for Diacylglycerol Lipase-α in Brain

(2013) Marc P. Baggelaar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Concise Guide to PHARMACOLOGY 2013/14: Enzymes

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Concise Guide to PHARMACOLOGY 2013/14: G Protein-Coupled Receptors

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

In vivocharacterization of the highly selective monoacylglycerol lipase inhibitor KML29: antinociceptive activity without cannabimimetic side effects

(2013) B M Ignatowska-Jankowska et al.   BRITISH JOURNAL OF PHARMACOLOGY

Modulating the endocannabinoid system in human health and disease - successes and failures

(2013) Pál Pacher et al.   FEBS Journal

Therapeutic Utility of Cannabinoid Receptor Type 2 (CB2) Selective Agonists

(2013) Sangdon Han et al.   JOURNAL OF MEDICINAL CHEMISTRY

The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands

(2013) Adam J. Pawson et al.   NUCLEIC ACIDS RESEARCH

β-Caryophyllene ameliorates cisplatin-induced nephrotoxicity in a cannabinoid 2 receptor-dependent manner

(2012) Béla Horváth et al.   FREE RADICAL BIOLOGY AND MEDICINE

Enzymatic formation of N-acylethanolamines from N-acylethanolamine plasmalogen through N-acylphosphatidylethanolamine-hydrolyzing phospholipase D-dependent and -independent pathways

(2011) Kazuhito Tsuboi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Protective Role of Cannabinoid Receptor Type 2 in a Mouse Model of Diabetic Nephropathy

(2011) F. Barutta et al.   DIABETES

Poly(ADP-ribose) polymerase-1 is a key mediator of cisplatin-induced kidney inflammation and injury

(2011) Partha Mukhopadhyay et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial-targeted antioxidants represent a promising approach for prevention of cisplatin-induced nephropathy

(2011) Partha Mukhopadhyay et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cannabinoid CB2 receptors protect against alcoholic liver disease by regulating Kupffer cell polarization in mice

(2011) Alexandre Louvet et al.   HEPATOLOGY

Discovery and Optimization of 1-(4-(Pyridin-2-yl)benzyl)imidazolidine-2,4-dione Derivatives As a Novel Class of Selective Cannabinoid CB2 Receptor Agonists

(2011) Mario van der Stelt et al.   JOURNAL OF MEDICINAL CHEMISTRY

Is lipid signaling through cannabinoid 2 receptors part of a protective system?

(2011) P. Pacher et al.   PROGRESS IN LIPID RESEARCH

CB1cannabinoid receptors promote oxidative/nitrosative stress, inflammation and cell death in a murine nephropathy model

(2010) Partha Mukhopadhyay et al.   BRITISH JOURNAL OF PHARMACOLOGY

Inhibitor of Fatty Acid Amide Hydrolase Normalizes Cardiovascular Function in Hypertension without Adverse Metabolic Effects

(2010) Grzegorz Godlewski et al.   CHEMISTRY & BIOLOGY

Enol Carbamates as Inhibitors of Fatty Acid Amide Hydrolase (FAAH) Endowed with High Selectivity for FAAH over the Other Targets of the Endocannabinoid System

(2010) Sonia Gattinoni et al.   ChemMedChem

Cannabinoid Receptor 1 Blockade Ameliorates Albuminuria in Experimental Diabetic Nephropathy

(2010) F. Barutta et al.   DIABETES

Beneficial paracrine effects of cannabinoid receptor 2 on liver injury and regeneration

(2010) Fatima Teixeira-Clerc et al.   HEPATOLOGY

Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system

(2010) Joel E Schlosburg et al.   NATURE NEUROSCIENCE

Cannabinoid-2 receptor limits inflammation, oxidative/nitrosative stress, and cell death in nephropathy

(2009) Partha Mukhopadhyay et al.   FREE RADICAL BIOLOGY AND MEDICINE

Activation of the cannabinoid 2 receptor (CB2) protects against experimental colitis

(2009) Martin A. Storr et al.   INFLAMMATORY BOWEL DISEASES

CB2 receptor activation attenuates microcirculatory dysfunction during cerebral ischemic/reperfusion injury

(2009) Ming Zhang et al.   MICROVASCULAR RESEARCH

Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo

(2009) J. Z. Long et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cisplatin nephrotoxicity: Mechanisms and renoprotective strategies

(2008) N. Pabla et al.   KIDNEY INTERNATIONAL

Species-specific in vitro pharmacological effects of the cannabinoid receptor 2 (CB2) selective ligand AM1241 and its resolved enantiomers

(2007) B Bingham et al.   BRITISH JOURNAL OF PHARMACOLOGY