Model for disordered proteins with strongly sequence-dependent liquid phase behavior

A gel phase promotes condensation of liquid P granules in Caenorhabditis elegans embryos

(2019) Andrea Putnam et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Complete Phase Diagram for Liquid–Liquid Phase Separation of Intrinsically Disordered Proteins

(2019) James McCarty et al.   Journal of Physical Chemistry Letters

The role of liquid-liquid phase separation in aggregation of the TDP-43 low complexity domain

(2019) W. Michael Babinchak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Temperature-Controlled Liquid–Liquid Phase Separation of Disordered Proteins

(2019) Gregory L. Dignon et al.   ACS Central Science

Breakdown of the law of rectilinear diameter and related surprises in the liquid-vapor coexistence in systems of patchy particles

(2019) Jorge R. Espinosa et al.   JOURNAL OF CHEMICAL PHYSICS

Three archetypical classes of macromolecular regulators of protein liquid–liquid phase separation

(2019) Archishman Ghosh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reentrant Phase Transitions and Non-Equilibrium Dynamics in Membraneless Organelles

(2018) Anthony N. Milin et al.   BIOCHEMISTRY

Functional Implications of Intracellular Phase Transitions

(2018) Alex S. Holehouse et al.   BIOCHEMISTRY

A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins

(2018) Jie Wang et al.   CELL

Physical principles of intracellular organization via active and passive phase transitions

(2018) Joel Berry et al.   REPORTS ON PROGRESS IN PHYSICS

Why Do Disordered and Structured Proteins Behave Differently in Phase Separation?

(2018) Huan-Xiang Zhou et al.   TRENDS IN BIOCHEMICAL SCIENCES

Liquid-Liquid Phase Separation of Patchy Particles Illuminates Diverse Effects of Regulatory Components on Protein Droplet Formation

(2018) Valery Nguemaha et al.   Scientific Reports

Relation between single-molecule properties and phase behavior of intrinsically disordered proteins

(2018) Gregory L. Dignon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Liquid Nuclear Condensates Mechanically Sense and Restructure the Genome

(2018) Yongdae Shin et al.   CELL

Mapping Local and Global Liquid Phase Behavior in Living Cells Using Photo-Oligomerizable Seeds

(2018) Dan Bracha et al.   CELL

Phase diagrams, mechanisms and unique characteristics of alternating-structured polymer self-assembly via simulations

(2018) Shanlong Li et al.   Science China-Chemistry

Evolution of Microphase Separation with Variations of Segments of Sequence-Controlled Multiblock Copolymers

(2017) Junliang Zhang et al.   MACROMOLECULES

Phase behaviour of disordered proteins underlying low density and high permeability of liquid organelles

(2017) Ming-Tzo Wei et al.   Nature Chemistry

Biomolecular condensates: organizers of cellular biochemistry

(2017) Salman F. Banani et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Charge pattern matching as a ‘fuzzy’ mode of molecular recognition for the functional phase separations of intrinsically disordered proteins

(2017) Yi-Hsuan Lin et al.   NEW JOURNAL OF PHYSICS

Liquid phase condensation in cell physiology and disease

(2017) Yongdae Shin et al.   SCIENCE

Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteins

(2017) Tyler S Harmon et al.   eLife

Protein Composition Determines the Effect of Crowding on the Properties of Disordered Proteins

(2016) Cayla M. Miller et al.   BIOPHYSICAL JOURNAL

ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure

(2016) Saumya Jain et al.   CELL

Effect of sequence dispersity on morphology of tapered diblock copolymers from molecular dynamics simulations

(2016) William G. Levine et al.   JOURNAL OF CHEMICAL PHYSICS

Fast Method for Computing Chemical Potentials and Liquid–Liquid Phase Equilibria of Macromolecular Solutions

(2016) Sanbo Qin et al.   JOURNAL OF PHYSICAL CHEMISTRY B

50th Anniversary Perspective: Block Polymers—Pure Potential

(2016) Christopher M. Bates et al.   MACROMOLECULES

Vapour–liquid phase equilibrium and surface tension of fully flexible Lennard–Jones chains

(2016) Kevin S. Silmore et al.   MOLECULAR PHYSICS

Sequence-Specific Polyampholyte Phase Separation in Membraneless Organelles

(2016) Yi-Hsuan Lin et al.   PHYSICAL REVIEW LETTERS

Critical Examination of the Colloidal Particle Model of Globular Proteins

(2015) Prasad S. Sarangapani et al.   BIOPHYSICAL JOURNAL

Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization

(2015) Amandine Molliex et al.   CELL

Strong scaling of general-purpose molecular dynamics simulations on GPUs

(2015) Jens Glaser et al.   COMPUTER PHYSICS COMMUNICATIONS

Nuclear bodies: the emerging biophysics of nucleoplasmic phases

(2015) Lian Zhu et al.   CURRENT OPINION IN CELL BIOLOGY

A theoretical method to compute sequence dependent configurational properties in charged polymers and proteins

(2015) Lucas Sawle et al.   JOURNAL OF CHEMICAL PHYSICS

Sequence- and Temperature-Dependent Properties of Unfolded and Disordered Proteins from Atomistic Simulations

(2015) Gül H. Zerze et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II

(2015) Kathleen A. Burke et al.   MOLECULAR CELL

Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles

(2015) Timothy J. Nott et al.   MOLECULAR CELL

Intrinsically disordered proteins in cellular signalling and regulation

(2015) Peter E. Wright et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

RNA transcription modulates phase transition-driven nuclear body assembly

(2015) Joel Berry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Customizing wormlike mesoscale structures via self-assembly of amphiphilic star polymers

(2015) Christian Koch et al.   Soft Matter

Competing Salt Effects on Phase Behavior of Protein Solutions: Tailoring of Protein Interaction by the Binding of Multivalent Ions and Charge Screening

(2014) Elena Jordan et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Reentrant Liquid-Liquid Phase Separation in Protein Solutions at Elevated Hydrostatic Pressures

(2014) Johannes Möller et al.   PHYSICAL REVIEW LETTERS

Computational Analysis Methods in Atomistic Modeling of Crystals

(2013) Alexander Stukowski   JOM

Conformations of intrinsically disordered proteins are influenced by linear sequence distributions of oppositely charged residues

(2013) R. K. Das et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Computer Study of the Association Behavior of Gradient Copolymers: Analysis of Simulation Results Based on a New Algorithm for Recognition and Classification of Aggregates

(2012) Jitka Kuldová et al.   MACROMOLECULAR THEORY AND SIMULATIONS

Effect of Architecture on the Phase Behavior of AB-Type Block Copolymer Melts

(2012) M. W. Matsen   MACROMOLECULES

Polymer scaling laws of unfolded and intrinsically disordered proteins quantified with single-molecule spectroscopy

(2012) H. Hofmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiblock Polymers: Panacea or Pandora's Box?

(2012) F. S. Bates et al.   SCIENCE

Phase behavior of gradient copolymer solutions: a Monte Carlo simulation study

(2012) Gunja Pandav et al.   Soft Matter

Reentrant Phase Diagram of Network Fluids

(2011) J. Russo et al.   PHYSICAL REVIEW LETTERS

Micelle formation, gelation and phase separation of amphiphilic multiblock copolymers†

(2011) Virginie Hugouvieux et al.   Soft Matter

Morphology prediction of block copolymers for drug delivery by mesoscale simulations

(2010) Paola Posocco et al.   JOURNAL OF MATERIALS CHEMISTRY

Net charge per residue modulates conformational ensembles of intrinsically disordered proteins

(2010) A. H. Mao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Universality of protein reentrant condensation in solution induced by multivalent metal ions

(2010) Fajun Zhang et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Coarse-Grained Molecular Dynamics Simulation of Ammonium Surfactant Self-Assemblies: Micelles and Vesicles

(2009) Rongliang Wu et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Visualization and analysis of atomistic simulation data with OVITO–the Open Visualization Tool

(2009) Alexander Stukowski   MODELLING AND SIMULATION IN MATERIALS SCIENCE AND ENGINEERING

Phase behavior and structure formation in linear multiblock copolymer solutions by Monte Carlo simulation

(2008) Marian E. Gindy et al.   JOURNAL OF CHEMICAL PHYSICS

Complex coacervation: A field theoretic simulation study of polyelectrolyte complexation

(2008) Jonghoon Lee et al.   JOURNAL OF CHEMICAL PHYSICS

ABSINTH: A new continuum solvation model for simulations of polypeptides in aqueous solutions

(2008) Andreas Vitalis et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

General purpose molecular dynamics simulations fully implemented on graphics processing units

(2008) Joshua A. Anderson et al.   JOURNAL OF COMPUTATIONAL PHYSICS

Amphiphilic Multiblock Copolymers: From Intramolecular Pearl Necklace to Layered Structures

(2008) Virginie Hugouvieux et al.   MACROMOLECULES

Reentrant Condensation of Proteins in Solution Induced by Multivalent Counterions

(2008) F. Zhang et al.   PHYSICAL REVIEW LETTERS