Structural and Functional Characterization of New SsoPox Variant Points to the Dimer Interface as a Driver for the Increase in Promiscuous Paraoxonase Activity

Innovative Biocatalysts as Tools to Detect and Inactivate Nerve Agents

(2018) Elena Porzio et al.   Scientific Reports

Rational engineering of a native hyperthermostable lactonase into a broad spectrum phosphotriesterase

(2017) Pauline Jacquet et al.   Scientific Reports

Functional Trade-Offs in Promiscuous Enzymes Cannot Be Explained by Intrinsic Mutational Robustness of the Native Activity

(2016) Miriam Kaltenbach et al.   PLoS Genetics

An efficient thermostable organophosphate hydrolase and its application in pesticide decontamination

(2015) Immacolata Del Giudice et al.   BIOTECHNOLOGY AND BIOENGINEERING

A review of photochemical approaches for the treatment of a wide range of pesticides

(2015) P. Venkata Laxma Reddy et al.   JOURNAL OF HAZARDOUS MATERIALS

Characterization of a phosphotriesterase-like lactonase from the hyperthermoacidophilic crenarchaeon Vulcanisaeta moutnovskia

(2014) Verena Kallnik et al.   JOURNAL OF BIOTECHNOLOGY

ThePDB_REDOserver for macromolecular structure model optimization

(2014) Robbie P. Joosten et al.   IUCrJ

Differential Active Site Loop Conformations Mediate Promiscuous Activities in the Lactonase SsoPox

(2013) Julien Hiblot et al.   PLoS One

U.N. Taps Special Labs to Investigate Syrian Attack

(2013) M. Enserink   SCIENCE

Mn2+ modulates the kinetic properties of an archaeal member of the PLL family

(2012) Elena Porzio et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Structural and Enzymatic characterization of the lactonase SisLac from Sulfolobus islandicus

(2012) Julien Hiblot et al.   PLoS One

A Further Biochemical Characterization of DrPLL the Thermophilic Lactonase from Deinococcus radiodurans

(2012) Luigi Mandrich et al.   PROTEIN AND PEPTIDE LETTERS

Characterisation of the organophosphate hydrolase catalytic activity of SsoPox

(2012) Julien Hiblot et al.   Scientific Reports

Destruction and Detection of Chemical Warfare Agents

(2011) Kibong Kim et al.   CHEMICAL REVIEWS

Catalytic detoxification

(2011) Frank M. Raushel   NATURE

Improving the promiscuous nerve agent hydrolase activity of a thermostable archaeal lactonase

(2010) Luigia Merone et al.   BIORESOURCE TECHNOLOGY

Directed Evolution of a Thermostable Quorum-quenching Lactonase from the Amidohydrolase Superfamily

(2010) Jeng Yeong Chow et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural basis for thermostability revealed through the identification and characterization of a highly thermostable phosphotriesterase-like lactonase from Geobacillus stearothermophilus

(2009) Renda Hawwa et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Structural determinants of the high thermal stability of SsoPox from the hyperthermophilic archaeon Sulfolobus solfataricus

(2009) Pompea Del Vecchio et al.   EXTREMOPHILES

Structure-Based and Random Mutagenesis Approaches Increase the Organophosphate-Degrading Activity of a Phosphotriesterase Homologue from Deinococcus radiodurans

(2009) Renda Hawwa et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural Basis for Natural Lactonase and Promiscuous Phosphotriesterase Activities

(2008) Mikael Elias et al.   JOURNAL OF MOLECULAR BIOLOGY