An efficient thermostable organophosphate hydrolase and its application in pesticide decontamination

Altering the substrate specificity of methyl parathion hydrolase with directed evolution

(2015) Tee-Kheang Ng et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Evaluation of genotoxic potential of commonly used organophosphate pesticides in peripheral blood lymphocytes of rats

(2014) A Ojha et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Bioremediation of pesticide contaminated water using an organophosphate degrading enzyme immobilized on nonwoven polyester textiles

(2013) Yuan Gao et al.   ENZYME AND MICROBIAL TECHNOLOGY

GroEL/ES Buffering and Compensatory Mutations Promote Protein Evolution by Stabilizing Folding Intermediates

(2013) Kirsten T. Wyganowski et al.   JOURNAL OF MOLECULAR BIOLOGY

Differential Active Site Loop Conformations Mediate Promiscuous Activities in the Lactonase SsoPox

(2013) Julien Hiblot et al.   PLoS One

Central respiratory failure during acute organophosphate poisoning

(2013) Jennifer L. Carey et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Enhancing the Promiscuous Phosphotriesterase Activity of a Thermostable Lactonase (GkaP) for the Efficient Degradation of Organophosphate Pesticides

(2012) Yu Zhang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Mn2+ modulates the kinetic properties of an archaeal member of the PLL family

(2012) Elena Porzio et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Structural and Enzymatic characterization of the lactonase SisLac from Sulfolobus islandicus

(2012) Julien Hiblot et al.   PLoS One

Immobilization of organophosphohydrolase OpdA from Agrobacterium radiobacter by overproduction at the surface of polyester inclusions inside engineered Escherichia coli

(2011) Paul A. Blatchford et al.   BIOTECHNOLOGY AND BIOENGINEERING

Directed evolution combined with rational design increases activity of GpdQ toward a non-physiological substrate and alters the oligomeric structure of the enzyme

(2011) Sylvia H-C. Yip et al.   PROTEIN ENGINEERING DESIGN & SELECTION

In vitro efficacy of paraoxonase 1 from multiple sources against various organophosphates

(2011) Manojkumar Valiyaveettil et al.   TOXICOLOGY IN VITRO

The organophosphate-degrading enzyme fromAgrobacterium radiobacterdisplays mechanistic flexibility for catalysis

(2010) Fernanda Ely et al.   BIOCHEMICAL JOURNAL

Improving the promiscuous nerve agent hydrolase activity of a thermostable archaeal lactonase

(2010) Luigia Merone et al.   BIORESOURCE TECHNOLOGY

Hyperthermophilic phosphotriesterases/lactonases for the environment and human health

(2010) Luigi Mandrich et al.   ENVIRONMENTAL TECHNOLOGY

Update on biochemical properties of recombinantPseudomonas diminutaphosphotriesterase

(2009) Eugénie Carletti et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Structure-Based and Random Mutagenesis Approaches Increase the Organophosphate-Degrading Activity of a Phosphotriesterase Homologue from Deinococcus radiodurans

(2009) Renda Hawwa et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural Basis for Natural Lactonase and Promiscuous Phosphotriesterase Activities

(2008) Mikael Elias et al.   JOURNAL OF MOLECULAR BIOLOGY

Sperm chromatin alteration and DNA damage by methyl-parathion, chlorpyrifos and diazinon and their oxon metabolites in human spermatozoa

(2008) Elsa Salazar-Arredondo et al.   REPRODUCTIVE TOXICOLOGY