Nuclear Argonaute Piwi Gene Mutation Affects rRNA by Inducing rRNA Fragment Accumulation, Antisense Expression, and Defective Processing in Drosophila Ovaries

Exonuclease domain mutants of yeast DIS3 display genome instability

(2019) Karissa L. Milbury et al.   Nucleus

PIWI pathway against viruses in insects

(2019) Anna Kolliopoulou et al.   Wiley Interdisciplinary Reviews-RNA

Nuclear Ccr4-Not mediates the degradation of telomeric and transposon transcripts at chromatin in the Drosophila germline

(2019) Maria Kordyukova et al.   NUCLEIC ACIDS RESEARCH

From “Cellular” RNA to “Smart” RNA: Multiple Roles of RNA in Genome Stability and Beyond

(2018) Flavia Michelini et al.   CHEMICAL REVIEWS

Identifying small RNAs derived from maternal- and somatic-type rRNAs in zebrafish development

(2018) Mauro D. Locati et al.   GENOME

Transcriptional and chromatin changes accompanying de novo formation of transgenic piRNA clusters

(2018) Natalia Akulenko et al.   RNA

siRNAs and piRNAs collaborate for transposon control in the two-spotted spider mite

(2018) Mosharrof Mondal et al.   RNA

Long non-coding RNA repertoire and targeting by nuclear exosome, cytoplasmic exonuclease and RNAi in fission yeast

(2018) Sophie Atkinson et al.   RNA

Surveillance-ready transcription: nuclear RNA decay as a default fate

(2018) Stefan Bresson et al.   Open Biology

Stress-induced nuclear depletion ofEntamoeba histolytica3’-5’exoribonuclease EhRrp6 and its role in growth and erythrophagocytosis

(2018) Shashi Shekhar Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Single Mechanism of Biogenesis, Initiated and Directed by PIWI Proteins, Explains piRNA Production in Most Animals

(2018) Ildar Gainetdinov et al.   MOLECULAR CELL

The somatic piRNA pathway controls germline transposition over generations

(2018) Bridlin Barckmann et al.   NUCLEIC ACIDS RESEARCH

Erroneous ribosomal RNAs promote the generation of antisense ribosomal siRNA

(2018) Chengming Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diverse RNA interference strategies in early-branching metazoans

(2018) Andrew D. Calcino et al.   BMC EVOLUTIONARY BIOLOGY

Keeping ribosomal DNA intact: a repeating challenge

(2018) Daniël O. Warmerdam et al.   CHROMOSOME RESEARCH

The nucleolar transcriptome regulates Piwi shuttling between the nucleolus and the nucleoplasm

(2018) Elena A. Mikhaleva et al.   CHROMOSOME RESEARCH

The antiviral piRNA response in mosquitoes?

(2018) Margus Varjak et al.   JOURNAL OF GENERAL VIROLOGY

Next-generation sequencing reveals two populations of damage-induced small RNAs at endogenous DNA double-strand breaks

(2018) Franziska Bonath et al.   NUCLEIC ACIDS RESEARCH

Accumulation of RNA on chromatin disrupts heterochromatic silencing

(2017) Cornelia Brönner et al.   GENOME RESEARCH

Small RNA Pathways That Protect the Somatic Genome

(2017) Seogang Hyun   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Participation of the piRNA pathway in recruiting a component of RNA polymerase I transcription initiation complex to germline cell nucleoli

(2017) E. A. Fefelova et al.   MOLECULAR BIOLOGY

Piwi Is Required during Drosophila Embryogenesis to License Dual-Strand piRNA Clusters for Transposon Repression in Adult Ovaries

(2017) Abdou Akkouche et al.   MOLECULAR CELL

A new layer of rRNA regulation by small interference RNAs and the nuclear RNAi pathway

(2017) Xufei Zhou et al.   RNA Biology

piRNA Biogenesis in Drosophila melanogaster

(2017) Xiawei Huang et al.   TRENDS IN GENETICS

Tailing and degradation of Argonaute-bound small RNAs protect the genome from uncontrolled RNAi

(2017) Paola Pisacane et al.   Nature Communications

Reconstitution of the complete pathway of ITS2 processing at the pre-ribosome

(2017) Lisa Fromm et al.   Nature Communications

Proliferation of Double-Strand Break-Resistant Polyploid Cells Requires Drosophila FANCD2

(2016) Heidi S. Bretscher et al.   DEVELOPMENTAL CELL

RNA helicase Spn-E is required to maintain Aub and AGO3 protein levels for piRNA silencing in the germline of Drosophila

(2016) Sergei S. Ryazansky et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

RNA interference in the Colorado potato beetle, Leptinotarsa decemlineata : Identification of key contributors

(2016) June-Sun Yoon et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Survival in Quiescence Requires the Euchromatic Deployment of Clr4/SUV39H by Argonaute-Associated Small RNAs

(2016) Richard I. Joh et al.   MOLECULAR CELL

Cutoff Suppresses RNA Polymerase II Termination to Ensure Expression of piRNA Precursors

(2016) Yung-Chia Ariel Chen et al.   MOLECULAR CELL

The Lupus Autoantigen La Prevents Mis-channeling of tRNA Fragments into the Human MicroRNA Pathway

(2016) Daniele Hasler et al.   MOLECULAR CELL

RNA Quality Control as a Key to Suppressing RNA Silencing of Endogenous Genes in Plants

(2016) Lin Liu et al.   Molecular Plant

Genetic and mechanistic diversity of piRNA 3′-end formation

(2016) Rippei Hayashi et al.   NATURE

Insertion of an Alu element in a lncRNA leads to primate-specific modulation of alternative splicing

(2016) Shanshan Hu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Production of small RNAs by mammalian Dicer

(2016) Eliska Svobodova et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Insertion of an Alu element in a lncRNA leads to primate-specific modulation of alternative splicing

(2016) Shanshan Hu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Breaks in the 45S rDNA Lead to Recombination-Mediated Loss of Repeats

(2016) Daniël O. Warmerdam et al.   Cell Reports

Maternal piRNAs Are Essential for Germline Development following De Novo Establishment of Endo-siRNAs in Caenorhabditis elegans

(2015) Bruno F.M. de Albuquerque et al.   DEVELOPMENTAL CELL

piRNAs and piRNA-Dependent siRNAs Protect Conserved and Essential C. elegans Genes from Misrouting into the RNAi Pathway

(2015) Carolyn M. Phillips et al.   DEVELOPMENTAL CELL

Mechanism of siRNA production from repetitive DNA

(2015) Qiuying Yang et al.   GENES & DEVELOPMENT

A localized nucleolar DNA damage response facilitates recruitment of the homology-directed repair machinery independent of cell cycle stage

(2015) Marjolein van Sluis et al.   GENES & DEVELOPMENT

piRNA-guided slicing of transposon transcripts enforces their transcriptional silencing via specifying the nuclear piRNA repertoire

(2015) Kirsten-André Senti et al.   GENES & DEVELOPMENT

Paramutation in Drosophila Requires Both Nuclear and Cytoplasmic Actors of the piRNA Pathway and Induces Cis-spreading of piRNA Production

(2015) C. Hermant et al.   GENETICS

Piwi protein as a nucleolus visitor in Drosophila melanogaster

(2015) E. A. Mikhaleva et al.   MOLECULAR BIOLOGY

Coordinated Ribosomal ITS2 RNA Processing by the Las1 Complex Integrating Endonuclease, Polynucleotide Kinase, and Exonuclease Activities

(2015) Lisa Gasse et al.   MOLECULAR CELL

RNA-mediated epigenetic regulation of gene expression

(2015) Daniel Holoch et al.   NATURE REVIEWS GENETICS

Telomeric repeat silencing in germ cells is essential for early development inDrosophila

(2015) Valeriya Morgunova et al.   NUCLEIC ACIDS RESEARCH

A deeply conserved, noncanonical miRNA hosted by ribosomal DNA

(2015) Li-Ling Chak et al.   RNA

piRNA-guided slicing specifies transcripts for Zucchini-dependent, phased piRNA biogenesis

(2015) F. Mohn et al.   SCIENCE

piRNA-guided transposon cleavage initiates Zucchini-dependent, phased piRNA production

(2015) B. W. Han et al.   SCIENCE

Breaking bad: R-loops and genome integrity

(2015) Julie Sollier et al.   TRENDS IN CELL BIOLOGY

MIWI2 and MILI Have Differential Effects on piRNA Biogenesis and DNA Methylation

(2015) Sergei A. Manakov et al.   Cell Reports

Dicer Promotes Transcription Termination at Sites of Replication Stress to Maintain Genome Stability

(2014) Stephane E. Castel et al.   CELL

Renaissance of mammalian endogenous RNAi

(2014) Petr Svoboda   FEBS LETTERS

Incomplete replication generates somatic DNA alterations withinDrosophilapolytene salivary gland cells

(2014) Will Yarosh et al.   GENES & DEVELOPMENT

Retrotransposons and pseudogenes regulate mRNAs and lncRNAs via the piRNA pathway in the germline

(2014) Toshiaki Watanabe et al.   GENOME RESEARCH

Human nuclear Dicer restricts the deleterious accumulation of endogenous double-stranded RNA

(2014) Eleanor White et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Virus infection triggers widespread silencing of host genes by a distinct class of endogenous siRNAs inArabidopsis

(2014) Mengji Cao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Changes in rRNA Transcription Influence Proliferation and Cell Fate Within a Stem Cell Lineage

(2014) Q. Zhang et al.   SCIENCE

Euchromatic Transposon Insertions Trigger Production of Novel Pi- and Endo-siRNAs at the Target Sites in the Drosophila Germline

(2014) Sergey Shpiz et al.   PLoS Genetics

Low Levels of p53 Protein and Chromatin Silencing of p53 Target Genes Repress Apoptosis in Drosophila Endocycling Cells

(2014) Bingqing Zhang et al.   PLoS Genetics

An overview of pre-ribosomal RNA processing in eukaryotes

(2014) Anthony K. Henras et al.   Wiley Interdisciplinary Reviews-RNA

Nucleolar stress with and without p53

(2014) Allison James et al.   Nucleus

Gene regulation by non-coding RNAs

(2013) Veena S. Patil et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Noisy silence

(2013) Holger Bierhoff et al.   Epigenetics

Piwi induces piRNA-guided transcriptional silencing and establishment of a repressive chromatin state

(2013) A. Le Thomas et al.   GENES & DEVELOPMENT

Functional analysis of the RNAi response in ovary-derived silkmoth Bm5 cells

(2013) Anna Kolliopoulou et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Argonaute and Triman Generate Dicer-Independent priRNAs and Mature siRNAs to Initiate Heterochromatin Formation

(2013) Mirela Marasovic et al.   MOLECULAR CELL

A Genome-wide RNAi Screen Draws a Genetic Framework for Transposon Control and Primary piRNA Biogenesis in Drosophila

(2013) Felix Muerdter et al.   MOLECULAR CELL

A Transcriptome-wide RNAi Screen in the Drosophila Ovary Reveals Factors of the Germline piRNA Pathway

(2013) Benjamin Czech et al.   MOLECULAR CELL

Profiling and Identification of Small rDNA-Derived RNAs and Their Potential Biological Functions

(2013) Haibin Wei et al.   PLoS One

R-Loop Mediated Transcription-Associated Recombination in trf4Δ Mutants Reveals New Links between RNA Surveillance and Genome Integrity

(2013) Sandra Gavaldá et al.   PLoS One

DNA Damage Sensing by the ATM and ATR Kinases

(2013) A. Marechal et al.   Cold Spring Harbor Perspectives in Biology

5S Ribosomal RNA Is an Essential Component of a Nascent Ribosomal Precursor Complex that Regulates the Hdm2-p53 Checkpoint

(2013) Giulio Donati et al.   Cell Reports

The 5S RNP Couples p53 Homeostasis to Ribosome Biogenesis and Nucleolar Stress

(2013) Katherine E. Sloan et al.   Cell Reports

Small RNA in the nucleus: the RNA-chromatin ping-pong

(2012) Ivan Olovnikov et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Rapid Cytoplasmic Turnover of Yeast Ribosomes in Response to Rapamycin Inhibition of TOR

(2012) D. G. Pestov et al.   MOLECULAR AND CELLULAR BIOLOGY

An Argonaute Protein Directs Nuclear Xrn2 Function

(2012) Daniele Hasler et al.   MOLECULAR CELL

The Cochaperone Shutdown Defines a Group of Biogenesis Factors Essential for All piRNA Populations in Drosophila

(2012) Daniel Olivieri et al.   MOLECULAR CELL

A Tetrahymena Piwi Bound to Mature tRNA 3′ Fragments Activates the Exonuclease Xrn2 for RNA Processing in the Nucleus

(2012) Mary T. Couvillion et al.   MOLECULAR CELL

RNAi triggered by specialized machinery silences developmental genes and retrotransposons

(2012) Soichiro Yamanaka et al.   NATURE

Rrp5p, Noc1p and Noc2p form a protein module which is part of early large ribosomal subunit precursors in S. cerevisiae

(2012) Thomas Hierlmeier et al.   NUCLEIC ACIDS RESEARCH

Heterochromatin Formation Promotes Longevity and Represses Ribosomal RNA Synthesis

(2012) Kimberly Larson et al.   PLoS Genetics

Assembly ofSaccharomyces cerevisiae60S ribosomal subunits: role of factors required for 27S pre-rRNA processing

(2011) Aarti Sahasranaman et al.   EMBO JOURNAL

DNA replication initiation patterns and spatial dynamics of the human ribosomal RNA gene loci

(2011) D. S. Dimitrova   JOURNAL OF CELL SCIENCE

The Evolutionarily Conserved Protein LAS1 Is Required for Pre-rRNA Processing at Both Ends of ITS2

(2011) S. Schillewaert et al.   MOLECULAR AND CELLULAR BIOLOGY

Interplay of transposon-silencing genes in the germline of Drosophila melanogaster

(2011) O. A. Sokolova et al.   MOLECULAR BIOLOGY

Heterotypic piRNA Ping-Pong Requires Qin, a Protein with Both E3 Ligase and Tudor Domains

(2011) Zhao Zhang et al.   MOLECULAR CELL

A genome-scale shRNA resource for transgenic RNAi in Drosophila

(2011) Jian-Quan Ni et al.   NATURE METHODS

Depletion of key protein components of the RISC pathway impairs pre-ribosomal RNA processing

(2011) Xue-hai Liang et al.   NUCLEIC ACIDS RESEARCH

Separation of stem cell maintenance and transposon silencing functions of Piwi protein

(2011) M. S. Klenov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Implication of Ccr4-Not complex function in mRNA quality control in Saccharomyces cerevisiae

(2011) J. Assenholt et al.   RNA

Clr4/Suv39 and RNA Quality Control Factors Cooperate to Trigger RNAi and Suppress Antisense RNA

(2011) K. Zhang et al.   SCIENCE

Eukaryotic 5S rRNA biogenesis

(2011) Martin Ciganda et al.   Wiley Interdisciplinary Reviews-RNA

An in vivo RNAi assay identifies major genetic and cellular requirements for primary piRNA biogenesis in Drosophila

(2010) Daniel Olivieri et al.   EMBO JOURNAL

Roles for the Yb body components Armitage and Yb in primary piRNA biogenesis in Drosophila

(2010) K. Saito et al.   GENES & DEVELOPMENT

The Yb Body, a Major Site for Piwi-associated RNA Biogenesis and a Gateway for Piwi Expression and Transport to the Nucleus in Somatic Cells

(2010) Hongying Qi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Why Does Insect RNA Look Degraded?

(2010) Eva C. Winnebeck et al.   JOURNAL OF INSECT SCIENCE

5′-end surveillance by Xrn2 acts as a shared mechanism for mammalian pre-rRNA maturation and decay

(2010) Minshi Wang et al.   NUCLEIC ACIDS RESEARCH

Genome-wide analysis reveals distinct substrate specificities of Rrp6, Dis3, and core exosome subunits

(2010) D. L. Kiss et al.   RNA

Functional characterization of the Drosophila MRP (mitochondrial RNA processing) RNA gene

(2010) M. D. Schneider et al.   RNA

Quelling targets the rDNA locus and functions in rDNA copy number control

(2009) Germano Cecere et al.   BMC MICROBIOLOGY

Signaling to p53: Ribosomal Proteins Find Their Way

(2009) Yanping Zhang et al.   CANCER CELL

Specialized piRNA Pathways Act in Germline and Somatic Tissues of the Drosophila Ovary

(2009) Colin D. Malone et al.   CELL

A Broadly Conserved Pathway Generates 3′UTR-Directed Primary piRNAs

(2009) Nicolas Robine et al.   CURRENT BIOLOGY

piRNAs mediate posttranscriptional retroelement silencing and localization to pi-bodies in theDrosophilagermline

(2009) Ai Khim Lim et al.   JOURNAL OF CELL BIOLOGY

A regulatory circuit for piwi by the large Maf gene traffic jam in Drosophila

(2009) Kuniaki Saito et al.   NATURE

qiRNA is a new type of small interfering RNA induced by DNA damage

(2009) Heng-Chi Lee et al.   NATURE

Histone H2A.Z cooperates with RNAi and heterochromatin factors to suppress antisense RNAs

(2009) Martin Zofall et al.   NATURE

ATP-dependent human RISC assembly pathways

(2009) Mayuko Yoda et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Loss of the Mili-interacting Tudor domain–containing protein-1 activates transposons and alters the Mili-associated small RNA profile

(2009) Michael Reuter et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The CCR4-NOT Complex Physically and Functionally Interacts with TRAMP and the Nuclear Exosome

(2009) Nowel Azzouz et al.   PLoS One

The endogenous siRNA pathway is involved in heterochromatin formation in Drosophila

(2009) Delphine Fagegaltier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A new role of the rDNA and nucleolus in the nucleus—rDNA instability maintains genome integrity

(2008) Takehiko Kobayashi   BIOESSAYS

Nop53p interacts with 5.8S rRNA co-transcriptionally, and regulates processing of pre-rRNA by the exosome

(2008) Daniela C. Granato et al.   FEBS Journal

A Yeast Exosome Cofactor, Mpp6, Functions in RNA Surveillance and in the Degradation of Noncoding RNA Transcripts

(2008) L. Milligan et al.   MOLECULAR AND CELLULAR BIOLOGY

Transcription Termination and RNA Degradation Contribute to Silencing of RNA Polymerase II Transcription within Heterochromatin

(2008) Lidia Vasiljeva et al.   MOLECULAR CELL

An endogenous small interfering RNA pathway in Drosophila

(2008) Benjamin Czech et al.   NATURE

TRAMP-mediated RNA surveillance prevents spurious entry of RNAs into the Schizosaccharomyces pombe siRNA pathway

(2008) Marc Bühler et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Apoptotic signals induce specific degradation of ribosomal RNA in yeast

(2008) Seweryn Mroczek et al.   NUCLEIC ACIDS RESEARCH

tRNA cleavage is a conserved response to oxidative stress in eukaryotes

(2008) D. M. Thompson et al.   RNA

Endogenous siRNAs Derived from Transposons and mRNAs in Drosophila Somatic Cells

(2008) M. Ghildiyal et al.   SCIENCE