Patterns of Expression of Purinergic Receptor P2RY12, a Putative Marker for Non-Activated Microglia, in Aged and Alzheimer’s Disease Brains

Molecular Mechanisms of Microglial Motility: Changes in Ageing and Alzheimer’s Disease

(2019) Franco-Bocanegra et al.   Cells

Extracellular ADP augments microglial inflammasome and NF‐κB activation via the P2Y12 receptor

(2019) Tomonori Suzuki et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Regulation of microglial TMEM119 and P2RY12 immunoreactivity in multiple sclerosis white and grey matter lesions is dependent on their inflammatory environment

(2019) Thecla A. van Wageningen et al.   Acta Neuropathologica Communications

Characterization of lysosomal proteins Progranulin and Prosaposin and their interactions in Alzheimer’s disease and aged brains: increased levels correlate with neuropathology

(2019) Anarmaa Mendsaikhan et al.   Acta Neuropathologica Communications

Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration

(2018) Aleksandra Deczkowska et al.   CELL

Diverse Brain Myeloid Expression Profiles Reveal Distinct Microglial Activation States and Aspects of Alzheimer’s Disease Not Evident in Mouse Models

(2018) Brad A. Friedman et al.   Cell Reports

Increased expression of toll-like receptor 3, an anti-viral signaling molecule, and related genes in Alzheimer's disease brains

(2018) Douglas G. Walker et al.   EXPERIMENTAL NEUROLOGY

Striatal Amyloid Plaque Density Predicts Braak Neurofibrillary Stage and Clinicopathological Alzheimer's Disease: Implications for Amyloid Imaging

(2018) Thomas G. Beach et al.   JOURNAL OF ALZHEIMERS DISEASE

Microglia in Alzheimer’s disease

(2017) Heela Sarlus et al.   JOURNAL OF CLINICAL INVESTIGATION

Staining of HLA-DR, Iba1 and CD68 in human microglia reveals partially overlapping expression depending on cellular morphology and pathology

(2017) Debbie A.E. Hendrickx et al.   JOURNAL OF NEUROIMMUNOLOGY

Transcriptomic analysis of purified human cortical microglia reveals age-associated changes

(2017) Thais F Galatro et al.   NATURE NEUROSCIENCE

Temporal Tracking of Microglia Activation in Neurodegeneration at Single-Cell Resolution

(2017) Hansruedi Mathys et al.   Cell Reports

Expression site of P2RY12 in residential microglial cells in astrocytomas correlates with M1 and M2 marker expression and tumor grade

(2017) Changbin Zhu et al.   Acta Neuropathologica Communications

Microglia show altered morphology and reduced arborization in human brain during aging and Alzheimer's disease

(2016) Danielle S. Davies et al.   BRAIN PATHOLOGY

P2Y12receptor is expressed on human microglia under physiological conditions throughout development and is sensitive to neuroinflammatory diseases

(2016) Alexander Mildner et al.   GLIA

Microglial immunophenotype in dementia with Alzheimer’s pathology

(2016) Thais Minett et al.   Journal of Neuroinflammation

A polarizing question: do M1 and M2 microglia exist?

(2016) Richard M Ransohoff   NATURE NEUROSCIENCE

New tools for studying microglia in the mouse and human CNS

(2016) Mariko L. Bennett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Non-Steroidal Anti-Inflammatory Drugs as a Treatment for Alzheimer’s Disease: A Systematic Review and Meta-Analysis of Treatment Effect

(2015) Marina Miguel-Álvarez et al.   DRUGS & AGING

TREM2 deficiency eliminates TREM2+inflammatory macrophages and ameliorates pathology in Alzheimer’s disease mouse models

(2015) Taylor R. Jay et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Effect of active Aβimmunotherapy on neurons in human Alzheimer's disease

(2015) Claire Paquet et al.   JOURNAL OF PATHOLOGY

Immune attack: the role of inflammation in Alzheimer disease

(2015) Frank L. Heppner et al.   NATURE REVIEWS NEUROSCIENCE

Association of CD33 polymorphism rs3865444 with Alzheimer's disease pathology and CD33 expression in human cerebral cortex

(2015) Douglas G. Walker et al.   NEUROBIOLOGY OF AGING

Arizona Study of Aging and Neurodegenerative Disorders and Brain and Body Donation Program

(2015) Thomas G. Beach et al.   NEUROPATHOLOGY

TREM2 Protein Expression Changes Correlate with Alzheimer's Disease Neurodegenerative Pathologies in Post-Mortem Temporal Cortices

(2014) Lih-Fen Lue et al.   BRAIN PATHOLOGY

Microglia is a Key Player in the Reduction of Stroke Damage Promoted by the New Antithrombotic Agent Ticagrelor

(2014) Paolo Gelosa et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Phenotypic profile of alternative activation marker CD163 is different in Alzheimer’s and Parkinson’s disease

(2014) Peixuan Pey et al.   Acta Neuropathologica Communications

Identification of a unique TGF-β–dependent molecular and functional signature in microglia

(2013) Oleg Butovsky et al.   NATURE NEUROSCIENCE

Microglial P2Y12 Deficiency/Inhibition Protects against Brain Ischemia

(2013) Corey M. Webster et al.   PLoS One

Review: Activation patterns of microglia and their identification in the human brain

(2012) D. Boche et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Regulation of Progranulin Expression in Human Microglia and Proteolysis of Progranulin by Matrix Metalloproteinase-12 (MMP-12)

(2012) Hyeon-Sook Suh et al.   PLoS One

P2Y12 receptors in platelets and other hematopoietic and non-hematopoietic cells

(2012) Christian Gachet   Purinergic Signalling

P2Y12 Receptor Protein in Cortical Gray Matter Lesions in Multiple Sclerosis

(2009) S. Amadio et al.   CEREBRAL CORTEX

The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments

(2009) S. A. Bustin et al.   CLINICAL CHEMISTRY

Progranulin expression correlates with dense-core amyloid plaque burden in Alzheimer disease mouse models

(2009) Sandra Pereson et al.   JOURNAL OF PATHOLOGY

Adenosine A2A receptor mediates microglial process retraction

(2009) Anna G Orr et al.   NATURE NEUROSCIENCE

The Sun Health Research Institute Brain Donation Program: Description and Eexperience, 1987–2007

(2008) Thomas G. Beach et al.   CELL AND TISSUE BANKING

Decreased expression of CD200 and CD200 receptor in Alzheimer's disease: A potential mechanism leading to chronic inflammation

(2008) Douglas G. Walker et al.   EXPERIMENTAL NEUROLOGY