Microglia is a Key Player in the Reduction of Stroke Damage Promoted by the New Antithrombotic Agent Ticagrelor

CX3CR1 deficiency induces an early protective inflammatory environment in ischemic mice

(2013) Stefano Fumagalli et al.   GLIA

Ticagrelor Enhances Adenosine-Induced Coronary Vasodilatory Responses in Humans

(2013) Ann Wittfeldt et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Microglial P2Y12 Deficiency/Inhibition Protects against Brain Ischemia

(2013) Corey M. Webster et al.   PLoS One

β-arrestin 2-dependent activation of ERK1/2 is required for ADP-induced paxillin phosphorylation at Ser83 and microglia chemotaxis

(2012) Sang-Hyun Lee et al.   GLIA

Time Course, Distribution and Cell Types of Induction of Transforming Growth Factor Betas following Middle Cerebral Artery Occlusion in the Rat Brain

(2012) Gabriella Pál et al.   PLoS One

Ticagrelor

(2011) James J. Nawarskas et al.   Cardiology in Review

Role of purinergic signalling in neuro-immune cells and adult neural progenitors

(2011) Marta Fumagalli   Frontiers in Bioscience-Landmark

The new P2Y-like receptor G protein-coupled receptor 17 mediates acute neuronal injury and late microgliosis after focal cerebral ischemia in rats

(2011) B. Zhao et al.   NEUROSCIENCE

TGF-β and LPS modulate ADP-induced migration of microglial cells through P2Y1 and P2Y12 receptor expression

(2010) Roberta De Simone et al.   JOURNAL OF NEUROCHEMISTRY

Tickets to the brain: Role of CCR2 and CX3CR1 in myeloid cell entry in the CNS

(2010) Marco Prinz et al.   JOURNAL OF NEUROIMMUNOLOGY

Adjunctive treatment with ticagrelor, but not clopidogrel, added to tPA enables sustained coronary artery recanalisation with recovery of myocardium perfusion in a canine coronary thrombosis model

(2010) Xiaorong Zhou et al.   THROMBOSIS AND HAEMOSTASIS

The P2Y-like receptor GPR17 as a sensor of damage and a new potential target in spinal cord injury

(2009) Stefania Ceruti et al.   BRAIN

Role of VASP phosphorylation for the regulation of microglia chemotaxis via the regulation of focal adhesion formation/maturation

(2009) S. Lee et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Adenosine A2A receptor mediates microglial process retraction

(2009) Anna G Orr et al.   NATURE NEUROSCIENCE

Ticagrelor versus Clopidogrel in Patients with Acute Coronary Syndromes

(2009) Lars Wallentin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Treatment with LXR agonists after focal cerebral ischemia prevents brain damage

(2008) Luigi Sironi et al.   FEBS LETTERS

The Recently Identified P2Y-Like Receptor GPR17 Is a Sensor of Brain Damage and a New Target for Brain Repair

(2008) Davide Lecca et al.   PLoS One