GM1 Ganglioside Is A Key Factor in Maintaining the Mammalian Neuronal Functions Avoiding Neurodegeneration

Pathophysiology of Ganglioside GM1 in Ischemic Stroke: Ganglioside GM1: A Critical Review

(2019) Wenchao Zhang et al.   CELL TRANSPLANTATION

The Neuroprotective Role of the GM1 Oligosaccharide, II3Neu5Ac-Gg4, in Neuroblastoma Cells

(2019) Elena Chiricozzi et al.   MOLECULAR NEUROBIOLOGY

GM 1 promotes TrkA‐mediated neuroblastoma cell differentiation by occupying a plasma membrane domain different from TrkA

(2019) Elena Chiricozzi et al.   JOURNAL OF NEUROCHEMISTRY

Pharmacological Manipulation of Trk, p75NTR, and NGF Balance Restores Memory Deficit in Global Ischemia/Reperfusion Model in Rats

(2019) Ali Mohamed Choucry et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

FTY720 Improves Behavior, Increases Brain Derived Neurotrophic Factor and Reduces α-Synuclein Pathology in Parkinsonian GM2 +/− Mice

(2019) Guadalupe Vidal-Martinez et al.   NEUROSCIENCE

Clinical efficacy of gangliosides on premature infants suffering from white matter damage and its effect on the levels of IL‑6, NSE and S100β

(2019) Xiaopeng Wang et al.   Experimental and Therapeutic Medicine

GM1 Ganglioside Modifies α-Synuclein Toxicity and is Neuroprotective in a Rat α-Synuclein Model of Parkinson’s Disease

(2019) Jay S. Schneider et al.   Scientific Reports

Gangliosides: Treatment Avenues in Neurodegenerative Disease

(2019) Pierre J. Magistretti et al.   Frontiers in Neurology

Ischaemic stroke

(2019) Bruce C. V. Campbell et al.   Nature Reviews Disease Primers

Parkinson’s disease recovery by GM1 oligosaccharide treatment in the B4galnt1+/− mouse model

(2019) Elena Chiricozzi et al.   Scientific Reports

Sex-Related Abnormalities in Substantia Nigra Lipids in Parkinson’s Disease

(2018) T. N. Seyfried et al.   ASN Neuro

On the use of cholera toxin

(2018) Elena Chiricozzi et al.   GLYCOCONJUGATE JOURNAL

Sphingolipids and neuronal degeneration in lysosomal storage disorders

(2018) Sara Grassi et al.   JOURNAL OF NEUROCHEMISTRY

Altered expression of genes involved in ganglioside biosynthesis in substantia nigra neurons in Parkinson’s disease

(2018) Jay S. Schneider   PLoS One

Ganglioside Metabolism and Parkinson's Disease

(2018) John Forsayeth et al.   Frontiers in Neuroscience

Labeled gangliosides: their synthesis and use in biological studies

(2018) Günter Schwarzmann   FEBS LETTERS

Neuronal membrane dynamics as fine regulator of sphingolipid composition

(2018) Massimo Aureli et al.   GLYCOCONJUGATE JOURNAL

Parkinsonian GM2 synthase knockout mice lacking mature gangliosides develop urinary dysfunction and neurogenic bladder

(2018) Carolina Gil-Tommee et al.   EXPERIMENTAL NEUROLOGY

Monosialotetrahexosy-1 ganglioside attenuates diabetes-associated cerebral ischemia/reperfusion injury through suppression of the endoplasmic reticulum stress-induced apoptosis

(2017) Danying Su et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Role of the GM1 ganglioside oligosaccharide portion in the TrkA-dependent neurite sprouting in neuroblastoma cells

(2017) Elena Chiricozzi et al.   JOURNAL OF NEUROCHEMISTRY

GM1 Ganglioside Inhibits β-Amyloid Oligomerization Induced by Sphingomyelin

(2016) Mariana Amaro et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Age-associated physiological and pathological changes at the blood–brain barrier: A review

(2016) Franciska Erdő et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Serum Antibodies to Glycans in Peripheral Neuropathies

(2016) Sandro Sonnino et al.   MOLECULAR NEUROBIOLOGY

Perinatal brain damage: The term infant

(2016) Henrik Hagberg et al.   NEUROBIOLOGY OF DISEASE

Protection against Experimental Stroke by Ganglioside GM1 Is Associated with the Inhibition of Autophagy

(2016) Li Li et al.   PLoS One

Alterations in Cholesterol and Ganglioside GM1 Content of Lipid Rafts in Platelets From Patients With Alzheimer Disease

(2015) Li Liu et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

GDNF signaling implemented by GM1 ganglioside; failure in Parkinson's disease and GM1-deficient murine model

(2015) Piotr Hadaczek et al.   EXPERIMENTAL NEUROLOGY

Symbol Nomenclature for Graphical Representations of Glycans

(2015) Ajit Varki et al.   GLYCOBIOLOGY

GM1 ganglioside and Alzheimer’s disease

(2015) Katsuhiko Yanagisawa   GLYCOCONJUGATE JOURNAL

The Possible Damaged Mechanism and the Preventive Effect of Monosialotetrahexosylganglioside in a Rat Model of Cerebral Ischemia-Reperfusion Injury

(2015) Jie Zhang et al.   Journal of Stroke & Cerebrovascular Diseases

GM1 ganglioside in Parkinson's disease: Pilot study of effects on dopamine transporter binding

(2015) Jay S. Schneider et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

GM1 Ganglioside: Past Studies and Future Potential

(2015) Massimo Aureli et al.   MOLECULAR NEUROBIOLOGY

The multi-tasked life of GM1 ganglioside, a true factotum of nature

(2015) Robert W. Ledeen et al.   TRENDS IN BIOCHEMICAL SCIENCES

Gangliosides: glycosphingolipids essential for normal neural development and function

(2015) Cara-Lynne Schengrund   TRENDS IN BIOCHEMICAL SCIENCES

The Possible Damaged Mechanism and the Preventive Effect of Monosialotetrahexosylganglioside in a Rat Model of Cerebral Ischemia-Reperfusion Injury

(2015) Jie Zhang et al.   Journal of Stroke & Cerebrovascular Diseases

Intraventricular Sialidase Administration Enhances GM1 Ganglioside Expression and Is Partially Neuroprotective in a Mouse Model of Parkinson’s Disease

(2015) Jay S. Schneider et al.   PLoS One

α-Synuclein Multimers Cluster Synaptic Vesicles and Attenuate Recycling

(2014) Lina Wang et al.   CURRENT BIOLOGY

Decreased Amyloid-β Pathologies by Intracerebral Loading of Glycosphingolipid-enriched Exosomes in Alzheimer Model Mice

(2014) Kohei Yuyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct interaction, instrumental for signaling processes, between LacCer and Lyn in the lipid rafts of neutrophil-like cells

(2014) Elena Chiricozzi et al.   JOURNAL OF LIPID RESEARCH

GM1 ganglioside enhances Ret signaling in striatum

(2014) Erin N. Newburn et al.   JOURNAL OF NEUROCHEMISTRY

Neu3 Sialidase-Mediated Ganglioside Conversion Is Necessary for Axon Regeneration and Is Blocked in CNS Axons

(2014) S. Kappagantula et al.   JOURNAL OF NEUROSCIENCE

N-Alpha-Acetylation of α-Synuclein Increases Its Helical Folding Propensity, GM1 Binding Specificity and Resistance to Aggregation

(2014) Tim Bartels et al.   PLoS One

Photoactivatable Lipid Probes for Studying Biomembranes by Photoaffinity Labeling

(2013) Yi Xia et al.   CHEMICAL REVIEWS

Gangliosides as regulators of cell signaling: ganglioside-protein interactions or ganglioside-driven membrane organization?

(2013) Sandro Sonnino et al.   JOURNAL OF NEUROCHEMISTRY

Lipid Rafts in Neurodegeneration and Neuroprotection

(2013) Sandro Sonnino et al.   MOLECULAR NEUROBIOLOGY

Introduction to the Guidelines for the Management of Acute Cervical Spine and Spinal Cord Injuries

(2013) Mark N. Hadley et al.   NEUROSURGERY

In Reply

(2013) Beverly C. Walters et al.   NEUROSURGERY

Guidelines for the Management of Acute Cervical Spine and Spinal Cord Injuries

(2013) Beverly C. Walters et al.   NEUROSURGERY

Mammalian sialidases: Physiological and pathological roles in cellular functions

(2012) T. Miyagi et al.   GLYCOBIOLOGY

Deficiency of ganglioside GM1 correlates with Parkinson's disease in mice and humans

(2012) Gusheng Wu et al.   JOURNAL OF NEUROSCIENCE RESEARCH

A randomized, controlled, delayed start trial of GM1 ganglioside in treated Parkinson's disease patients

(2012) Jay S. Schneider et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Toward a redefinition of Parkinson's disease

(2012) Matthew B. Stern et al.   MOVEMENT DISORDERS

Monosialoanglioside improves memory deficits and relieves oxidative stress in the hippocampus of rat model of Alzheimer’s disease

(2012) Rui Yang et al.   NEUROLOGICAL SCIENCES

Mice Lacking Major Brain Gangliosides Develop Parkinsonism

(2011) Gusheng Wu et al.   NEUROCHEMICAL RESEARCH

Secondary Alterations of Sphingolipid Metabolism in Lysosomal Storage Diseases

(2011) Alessandro Prinetti et al.   NEUROCHEMICAL RESEARCH

Imaging Mass Spectrometry Detection of Gangliosides Species in the Mouse Brain following Transient Focal Cerebral Ischemia and Long-Term Recovery

(2011) Shawn N. Whitehead et al.   PLoS One

Membrane Organization and Lipid Rafts

(2011) K. Simons et al.   Cold Spring Harbor Perspectives in Biology

Parenteral administration of GM1 ganglioside to presenile Alzheimer patients

(2010) L. Svennerholm et al.   ACTA NEUROLOGICA SCANDINAVICA

SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson’s disease

(2010) Pablo Garcia-Reitböck et al.   BRAIN

Monosialotetrahexosy-1 ganglioside attenuates diabetes-enhanced brain damage after transient forebrain ischemia and suppresses phosphorylation of ERK1/2 in the rat brain

(2010) Jian-Zhong Zhang et al.   BRAIN RESEARCH

Membrane Lipids, Selectively Diminished in Alzheimer Brains, Suggest Synapse Loss as a Primary Event in Early-Onset Form (Type I) and Demyelination in Late-Onset Form (Type II)

(2010) Lars Svennerholm et al.   JOURNAL OF NEUROCHEMISTRY

GM1 ganglioside in Parkinson's disease: Results of a five year open study

(2010) Jay S. Schneider et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Increased Expression of α-Synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering after Endocytosis

(2010) Venu M. Nemani et al.   NEURON

Age-dependent high-density clustering of GM1 ganglioside at presynaptic neuritic terminals promotes amyloid β-protein fibrillogenesis

(2008) Naoki Yamamoto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Thematic Review Series: Sphingolipids.Role of ganglioside metabolism in the pathogenesis of Alzheimer's disease—a review,

(2008) Toshio Ariga et al.   JOURNAL OF LIPID RESEARCH

Accelerated release of exosome-associated GM1 ganglioside (GM1) by endocytic pathway abnormality: another putative pathway for GM1-induced amyloid fibril formation

(2008) Kohei Yuyama et al.   JOURNAL OF NEUROCHEMISTRY

Elimination of GD3 synthase improves memory and reduces amyloid-β plaque load in transgenic mice

(2008) Alexandra Bernardo et al.   NEUROBIOLOGY OF AGING