4-methylumbelliferone Prevents Liver Fibrosis by Affecting Hyaluronan Deposition, FSTL1 Expression and Cell Localization

Umbelliferone Ameliorates CCl4-Induced Liver Fibrosis in Rats by Upregulating PPARγ and Attenuating Oxidative Stress, Inflammation, and TGF-β1/Smad3 Signaling

(2019) Ayman M. Mahmoud et al.   INFLAMMATION

Hyaluronan synthase 2–mediated hyaluronan production mediates Notch1 activation and liver fibrosis

(2019) Yoon Mee Yang et al.   Science Translational Medicine

Follistatin-Like 1 Promotes Bleomycin-Induced Pulmonary Fibrosis through the Transforming Growth Factor Beta 1/Mitogen-Activated Protein Kinase Signaling Pathway

(2018) Chen Wang et al.   CHINESE MEDICAL JOURNAL

Provisional matrix: A role for versican and hyaluronan

(2017) Thomas N. Wight   MATRIX BIOLOGY

Knockdown of Fstl1 attenuates hepatic stellate cell activation through the TGF-β1/Smad3 signaling pathway

(2017) Hongye Shang et al.   Molecular Medicine Reports

Mechanisms of hepatic stellate cell activation

(2017) Takuma Tsuchida et al.   Nature Reviews Gastroenterology & Hepatology

Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention

(2017) Zobair Younossi et al.   Nature Reviews Gastroenterology & Hepatology

Follistatin like-1 aggravates silica-induced mouse lung injury

(2017) Yinshan Fang et al.   Scientific Reports

Identification of Novel Fibrosis Modifiers by In Vivo siRNA Silencing

(2017) Elisabeth H. Vollmann et al.   Molecular Therapy-Nucleic Acids

The pharmacokinetics and dosing of oral 4-methylumbelliferone for inhibition of hyaluronan synthesis in mice

(2016) H. F. Kuipers et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Follistatin‐like 1 promotes cardiac fibroblast activation and protects the heart from rupture

(2016) Sonomi Maruyama et al.   EMBO Molecular Medicine

Antioxidant Activities of 4-Methylumbelliferone Derivatives

(2016) Yasameen K. Al-Majedy et al.   PLoS One

Molecular and proteomic insight into Notch1 characterization in hepatocellular carcinoma

(2016) Catia Giovannini et al.   Oncotarget

4-Methylumbelliferone inhibits hepatocellular carcinoma growth by decreasing IL-6 production and angiogenesis

(2015) Flavia Piccioni et al.   GLYCOBIOLOGY

Blocking follistatin-like 1 attenuates bleomycin-induced pulmonary fibrosis in mice

(2015) Yingying Dong et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The carbon tetrachloride model in mice

(2015) D Scholten et al.   LABORATORY ANIMALS

Hyaluronan’s Role in Fibrosis: A Pathogenic Factor or a Passive Player?

(2015) Sami Albeiroti et al.   Biomed Research International

4-Methylumbelliferone Treatment and Hyaluronan Inhibition as a Therapeutic Strategy in Inflammation, Autoimmunity, and Cancer

(2015) Nadine Nagy et al.   Frontiers in Immunology

Histochemical Detection of Collagen Fibers by Sirius Red/Fast Green Is More Sensitive than van Gieson or Sirius Red Alone in Normal and Inflamed Rat Colon

(2015) Cristina Segnani et al.   PLoS One

‘See-saw’ expression of microRNA-198 and FSTL1 from a single transcript in wound healing

(2013) Gopinath M. Sundaram et al.   NATURE

Second harmonic generation microscopy for quantitative analysis of collagen fibrillar structure

(2012) Xiyi Chen et al.   Nature Protocols

Antitumor effects of hyaluronic acid inhibitor 4-methylumbelliferone in an orthotopic hepatocellular carcinoma model in mice

(2011) F. Piccioni et al.   GLYCOBIOLOGY

4-Methylumbelliferone inhibits hyaluronan synthesis by depletion of cellular UDP-glucuronic acid and downregulation of hyaluronan synthase 2 and 3

(2009) Anne Kultti et al.   EXPERIMENTAL CELL RESEARCH

A novel model of CCl4-induced cirrhosis with ascites in the mouse

(2009) Marco Domenicali et al.   JOURNAL OF HEPATOLOGY

Human CYP3A4 and Murine Cyp3A11 Are Regulated by Equol and Genistein via the Pregnane X Receptor in a Species-Specific Manner

(2009) Yilan Li et al.   JOURNAL OF NUTRITION