Peptidylarginine Deiminase Isozyme-Specific PAD2, PAD3 and PAD4 Inhibitors Differentially Modulate Extracellular Vesicle Signatures and Cell Invasion in Two Glioblastoma Multiforme Cell Lines
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Peptidylarginine Deiminase Isozyme-Specific PAD2, PAD3 and PAD4 Inhibitors Differentially Modulate Extracellular Vesicle Signatures and Cell Invasion in Two Glioblastoma Multiforme Cell Lines
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 21, Issue 4, Pages 1495
Publisher
MDPI AG
Online
2020-02-24
DOI
10.3390/ijms21041495
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Short non-coding RNA sequencing of glioblastoma extracellular vesicles
- (2020) Tristan de Mooij et al. JOURNAL OF NEURO-ONCOLOGY
- Extracellular Vesicle-Mediated Communication between the Glioblastoma and Its Microenvironment
- (2020) Esperanza R. Matarredona et al. Cells
- Deiminated proteins and extracellular vesicles - Novel serum biomarkers in whales and orca
- (2020) Bergljót Magnadóttir et al. Comparative Biochemistry and Physiology D-Genomics & Proteomics
- Filopodome Mapping Identifies p130Cas as a Mechanosensitive Regulator of Filopodia Stability
- (2019) Guillaume Jacquemet et al. CURRENT BIOLOGY
- IDH3α regulates one-carbon metabolism in glioblastoma
- (2019) Jasmine L. May et al. Science Advances
- Prohibitins: A Critical Role in Mitochondrial Functions and Implication in Diseases
- (2019) Anna Signorile et al. Cells
- Phenotypic Plasticity of Invasive Edge Glioma Stem-like Cells in Response to Ionizing Radiation
- (2019) Mutsuko Minata et al. Cell Reports
- Evaluation of Glycolytic Response to Multiple Classes of Anti-glioblastoma Drugs by Noninvasive Measurement of Pyruvate Kinase M2 Using [18F]DASA-23
- (2019) Corinne Beinat et al. MOLECULAR IMAGING AND BIOLOGY
- Peptidylarginine Deiminase Inhibitors Reduce Bacterial Membrane Vesicle Release and Sensitize Bacteria to Antibiotic Treatment
- (2019) Uchini S. Kosgodage et al. Frontiers in Cellular and Infection Microbiology
- Comparative Transcriptomic Analysis of Temozolomide Resistant Primary GBM Stem-Like Cells and Recurrent GBM Identifies Up-Regulation of the Carbonic Anhydrase CA2 Gene as Resistance Factor
- (2019) Ricarda Hannen et al. Cancers
- Potential Therapeutic Effects of Exosomes Packed With a miR-21-Sponge Construct in a Rat Model of Glioblastoma
- (2019) Hamideh Monfared et al. Frontiers in Oncology
- Epstein-Barr virus infection in gliomas
- (2019) S. Limam et al. Current Research in Translational Medicine
- Circulating biomarkers in patients with glioblastoma
- (2019) Juliana Müller Bark et al. BRITISH JOURNAL OF CANCER
- Post-Translational Deimination of Immunological and Metabolic Protein Markers in Plasma and Extracellular Vesicles of Naked Mole-Rat (Heterocephalus glaber)
- (2019) Matthew E. Pamenter et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Large and small extracellular vesicles released by glioma cells in vitro and in vivo
- (2019) Anudeep Yekula et al. Journal of Extracellular Vesicles
- Glioblastoma extracellular vesicles induce the tumour-promoting transformation of neural stem cells
- (2019) Jian Wang et al. CANCER LETTERS
- Profiling of novel circulating microRNAs as a non-invasive biomarker in diagnosis and follow-up of high and low-grade gliomas
- (2019) Alireza Tabibkhooei et al. CLINICAL NEUROLOGY AND NEUROSURGERY
- Extracellular vesicles and their role in glioblastoma
- (2019) Clarissa A. Whitehead et al. CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES
- Moesin, an ERM family member, regulates hepatic fibrosis
- (2019) Serhan Karvar et al. HEPATOLOGY
- Moesin Up-regulation Is Associated with Enhanced Tumor Progression Imaged Non-invasively in an Orthotopic Mouse Model of Human Glioblastoma
- (2018) QING WANG et al. ANTICANCER RESEARCH
- Integrative analysis of rewired central metabolism in temozolomide resistant cells
- (2018) Selva Rupa C. Immanuel et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Temozolomide affects Extracellular Vesicles Released by Glioblastoma Cells
- (2018) Gwennan André-Grégoire et al. BIOCHIMIE
- Glioblastoma quo vadis : Will migration and invasiveness reemerge as therapeutic targets?
- (2018) Florence Lefranc et al. CANCER TREATMENT REVIEWS
- CircSMARCA5 Inhibits Migration of Glioblastoma Multiforme Cells by Regulating a Molecular Axis Involving Splicing Factors SRSF1/SRSF3/PTB
- (2018) Davide Barbagallo et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Significance of prohibitin domain family in tumorigenesis and its implication in cancer diagnosis and treatment
- (2018) Jie Yang et al. Cell Death & Disease
- Identification of Key Candidate Proteins and Pathways Associated with Temozolomide Resistance in Glioblastoma Based on Subcellular Proteomics and Bioinformatical Analysis
- (2018) Guo-zhong Yi et al. Biomed Research International
- Cannabinoids in Glioblastoma Therapy: New Applications for Old Drugs
- (2018) Claudia A. Dumitru et al. Frontiers in Molecular Neuroscience
- Epstein–Barr Virus in Gliomas: Cause, Association, or Artifact?
- (2018) Saghir Akhtar et al. Frontiers in Oncology
- Targeting Glioma Initiating Cells with A combined therapy of cannabinoids and temozolomide
- (2018) Israel López-Valero et al. BIOCHEMICAL PHARMACOLOGY
- Significance of Glioma Stem-Like Cells in the Tumor Periphery That Express High Levels of CD44 in Tumor Invasion, Early Progression, and Poor Prognosis in Glioblastoma
- (2018) Masahiro Nishikawa et al. Stem Cells International
- Cannabidiol (CBD) Is a Novel Inhibitor for Exosome and Microvesicle (EMV) Release in Cancer
- (2018) Uchini S. Kosgodage et al. Frontiers in Pharmacology
- Peptidylarginine Deiminases Post-Translationally Deiminate Prohibitin and Modulate Extracellular Vesicle Release and MicroRNAs in Glioblastoma Multiforme
- (2018) Uchini Kosgodage et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Moesin is an independent prognostic marker for ER‑positive breast cancer
- (2018) Lifeng Yu et al. Oncology Letters
- Mitochondrial Quality Control Mechanisms and the PHB (Prohibitin) Complex
- (2018) Blanca Hernando-Rodríguez et al. Cells
- Cannabidiol Affects Extracellular Vesicle Release, miR21 and miR126, and Reduces Prohibitin Protein in Glioblastoma Multiforme Cells
- (2018) Uchini S. Kosgodage et al. Translational Oncology
- Treatment of novel IL17A inhibitor in glioblastoma implementing 3rd generation co-culture cell line and patient-derived tumor model
- (2017) Md Shamsuddin Sultan Khan et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Chloramidine/Bisindolylmaleimide-I-Mediated Inhibition of Exosome and Microvesicle Release and Enhanced Efficacy of Cancer Chemotherapy
- (2017) Uchini Kosgodage et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Peptidylarginine Deiminases—Roles in Cancer and Neurodegeneration and Possible Avenues for Therapeutic Intervention via Modulation of Exosome and Microvesicle (EMV) Release?
- (2017) Sigrun Lange et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The emergent role of exosomes in glioma
- (2017) J. Gourlay et al. JOURNAL OF CLINICAL NEUROSCIENCE
- Development of a Selective Inhibitor of Protein Arginine Deiminase 2
- (2017) Aaron Muth et al. JOURNAL OF MEDICINAL CHEMISTRY
- Distinct Effects of miR-210 Reduction on Neurogenesis: Increased Neuronal Survival of Inflammation But Reduced Proliferation Associated with Mitochondrial Enhancement
- (2017) Ludmila A. Voloboueva et al. JOURNAL OF NEUROSCIENCE
- 3-Bromopyruvate treatment induces alterations of metabolic and stress-related pathways in glioblastoma cells
- (2017) Davide Chiasserini et al. Journal of Proteomics
- Proteome Analysis of Hypoxic Glioblastoma Cells Reveals Sequential Metabolic Adaptation of One-Carbon Metabolic Pathways
- (2017) Kangling Zhang et al. MOLECULAR & CELLULAR PROTEOMICS
- Protein moonlighting: what is it, and why is it important?
- (2017) Constance J. Jeffery PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Coding and noncoding landscape of extracellular RNA released by human glioma stem cells
- (2017) Zhiyun Wei et al. Nature Communications
- Bacterial Carriers for Glioblastoma Therapy
- (2017) Nalini Mehta et al. Molecular Therapy-Oncolytics
- Inhibition of HIF1α and PDK Induces Cell Death of Glioblastoma Multiforme
- (2017) Jiwon Esther Han et al. Experimental Neurobiology
- The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
- (2016) David N. Louis et al. ACTA NEUROPATHOLOGICA
- Down-regulation of MicroRNA-126 in Glioblastoma and its Correlation with Patient Prognosis: A Pilot Study
- (2016) IN BO HAN et al. ANTICANCER RESEARCH
- Cancer statistics, 2016
- (2016) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Modulation of MicroRNAs 34a and 21 Affects Viability, Senescence, and Invasion in Glioblastoma Multiforme
- (2016) Yuan Yin et al. Journal of Biomedical Nanotechnology
- Induction of peptidylarginine deiminase 2 and 3 by dibutyryl cAMP via cAMP-PKA signaling in human astrocytoma U-251MG cells
- (2016) Hirofumi Masutomi et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Dynamics of circulating hypoxia-mediated miRNAs and tumor response in patients with high-grade glioma treated with bevacizumab
- (2016) Tali Siegal et al. JOURNAL OF NEUROSURGERY
- MiR-126 Regulates the ERK Pathway via Targeting KRAS to Inhibit the Glioma Cell Proliferation and Invasion
- (2016) Yang Li et al. MOLECULAR NEUROBIOLOGY
- Advances in the targeting of HIF-1α and future therapeutic strategies for glioblastoma multiforme
- (2016) Gang Wang et al. ONCOLOGY REPORTS
- L-type calcium channels regulate filopodia stability and cancer cell invasion downstream of integrin signalling
- (2016) Guillaume Jacquemet et al. Nature Communications
- Microvesicle removal of anticancer drugs contributes to drug resistance in human pancreatic cancer cells
- (2016) Vandhana Muralidharan-Chari et al. Oncotarget
- Peptidylarginine Deiminases as Drug Targets in Neonatal Hypoxic–Ischemic Encephalopathy
- (2016) Sigrun Lange Frontiers in Neurology
- Multifaceted role of prohibitin in cell survival and apoptosis
- (2015) Ya-Ting Peng et al. APOPTOSIS
- Serum microRNA-210 as a potential noninvasive biomarker for the diagnosis and prognosis of glioma
- (2015) N-s Lai et al. BRITISH JOURNAL OF CANCER
- Nuclear Trapping through Inhibition of Exosomal Export by Indomethacin Increases Cytostatic Efficacy of Doxorubicin and Pixantrone
- (2015) R. Koch et al. CLINICAL CANCER RESEARCH
- Protein Arginine Deiminases and Associated Citrullination: Physiological Functions and Diseases Associated with Dysregulation
- (2015) Erin Witalison et al. CURRENT DRUG TARGETS
- Filopodia in cell adhesion, 3D migration and cancer cell invasion
- (2015) Guillaume Jacquemet et al. CURRENT OPINION IN CELL BIOLOGY
- Hormony tarczycy w ośrodkowym układzie nerwowym (OUN) i ich wpływ na nowotworzenie, zwłaszcza na rozwój i przebieg glioblastoma multiforme — hipoteza badawcza
- (2015) Paweł Nauman Endokrynologia Polska
- Glioblastoma in England: 2007–2011
- (2015) Andrew Brodbelt et al. EUROPEAN JOURNAL OF CANCER
- MiRNA-21 silencing mediated by tumor-targeted nanoparticles combined with sunitinib: A new multimodal gene therapy approach for glioblastoma
- (2015) Pedro M. Costa et al. JOURNAL OF CONTROLLED RELEASE
- miRNA contents of cerebrospinal fluid extracellular vesicles in glioblastoma patients
- (2015) Johnny C. Akers et al. JOURNAL OF NEURO-ONCOLOGY
- Analysis of gene expression profiles associated with glioma progression
- (2015) GUOZHANG HU et al. Molecular Medicine Reports
- Directly visualized glioblastoma-derived extracellular vesicles transfer RNA to microglia/macrophages in the brain
- (2015) Kristan E. van der Vos et al. NEURO-ONCOLOGY
- Inhibition of microvesiculation sensitizes prostate cancer cells to chemotherapy and reduces docetaxel dose required to limit tumor growth in vivo
- (2015) Samireh Jorfi et al. Scientific Reports
- Protein moonlighting: a new factor in biology and medicine
- (2014) Brian Henderson et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Modulation of calcium-induced cell death in human neural stem cells by the novel peptidylarginine deiminase–AIF pathway
- (2014) Kin Pong U et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Hypoxic signature of microRNAs in glioblastoma: insights from small RNA deep sequencing
- (2014) Rahul Agrawal et al. BMC GENOMICS
- Peptidyl Arginine Deiminase fromPorphyromonas gingivalisAbolishes Anaphylatoxin C5a Activity
- (2014) Ewa Bielecka et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Peptidylarginine deiminases: novel drug targets for prevention of neuronal damage following hypoxic ischemic insult (HI) in neonates
- (2014) Sigrun Lange et al. JOURNAL OF NEUROCHEMISTRY
- Belonging to a network—microRNAs, extracellular vesicles, and the glioblastoma microenvironment
- (2014) Jakub Godlewski et al. NEURO-ONCOLOGY
- Hypoxia-inducible factor–1 and associated upstream and downstream proteins in the pathophysiology and management of glioblastoma
- (2014) Matthew Womeldorff et al. Neurosurgical Focus
- Extracellular vesicles as modulators of cell-to-cell communication in the healthy and diseased brain
- (2014) D. M. Pegtel et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Exosome Release and Low pH Belong to a Framework of Resistance of Human Melanoma Cells to Cisplatin
- (2014) Cristina Federici et al. PLoS One
- A MiRNA Signature for Defining Aggressive Phenotype and Prognosis in Gliomas
- (2014) Raffaela Barbano et al. PLoS One
- Peptidylarginine deiminases in citrullination, gene regulation, health and pathogenesis
- (2013) Shu Wang et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Blood/plasma secretome and microvesicles
- (2013) Jameel M. Inal et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Emerging roles of store-operated Ca2+entry through STIM and ORAI proteins in immunity, hemostasis and cancer
- (2013) Wolfgang Bergmeier et al. Channels
- Prospective study of carmustine wafers in combination with 6-month metronomic temozolomide and radiation therapy in newly diagnosed glioblastoma: preliminary results
- (2013) Andrea Salmaggi et al. JOURNAL OF NEUROSURGERY
- STIM1 and Orai1 mediate CRAC channel activity and are essential for human glioblastoma invasion
- (2013) Rajender K. Motiani et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Blockade of store-operated Ca2+ entry inhibits hepatocarcinoma cell migration and invasion by regulating focal adhesion turnover
- (2012) Ning Yang et al. CANCER LETTERS
- Moesin Is a Glioma Progression Marker That Induces Proliferation and Wnt/ -Catenin Pathway Activation via Interaction with CD44
- (2012) X. Zhu et al. CANCER RESEARCH
- Glucose metabolism via the pentose phosphate pathway, glycolysis and Krebs cycle in an orthotopic mouse model of human brain tumors
- (2012) Isaac Marin-Valencia et al. NMR IN BIOMEDICINE
- Changes in the expression of proteins associated with aerobic glycolysis and cell migration are involved in tumorigenic ability of two glioma cell lines
- (2012) Anelisa Ramão et al. Proteome Science
- Calcium entry via ORAI1 regulates glioblastoma cell proliferation and apoptosis
- (2011) Huiling Liu et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- ORAI1-Mediated Calcium Influx in Lactation and in Breast Cancer
- (2011) D. McAndrew et al. MOLECULAR CANCER THERAPEUTICS
- Normal human monocytes exposed to glioma cells acquire myeloid-derived suppressor cell-like properties
- (2011) Jennifer C. Rodrigues et al. NEURO-ONCOLOGY
- Calcium store sensor stromal-interaction molecule 1-dependent signaling plays an important role in cervical cancer growth, migration, and angiogenesis
- (2011) Y.-F. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Substrate Specificity and Kinetic Studies of PADs 1, 3, and 4 Identify Potent and Selective Inhibitors of Protein Arginine Deiminase 3
- (2010) Bryan Knuckley et al. BIOCHEMISTRY
- Necroptosis: A novel therapeutic target for glioblastoma
- (2010) Yu-Gang Jiang et al. MEDICAL HYPOTHESES
- Wnt-11 promotes neuroendocrine-like differentiation, survival and migration of prostate cancer cells
- (2010) Pinar Uysal-Onganer et al. Molecular Cancer
- Survival signalling and apoptosis resistance in glioblastomas: opportunities for targeted therapeutics
- (2010) Camilla Krakstad et al. Molecular Cancer
- MicroRNA-210 Regulates Mitochondrial Free Radical Response to Hypoxia and Krebs Cycle in Cancer Cells by Targeting Iron Sulfur Cluster Protein ISCU
- (2010) Elena Favaro et al. PLoS One
- MiR-210 – micromanager of the hypoxia pathway
- (2010) Xin Huang et al. TRENDS IN MOLECULAR MEDICINE
- Orai1 and STIM1 Are Critical for Breast Tumor Cell Migration and Metastasis
- (2009) Shengyu Yang et al. CANCER CELL
- Stromal Interaction Molecule (STIM) 1 and STIM2 Calcium Sensing Regions Exhibit Distinct Unfolding and Oligomerization Kinetics
- (2008) Peter B. Stathopulos et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MicroRNA-210 Modulates Endothelial Cell Response to Hypoxia and Inhibits the Receptor Tyrosine Kinase Ligand Ephrin-A3
- (2008) Pasquale Fasanaro et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
- (2008) Johan Skog et al. NATURE CELL BIOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search