The Emerging Role of Mechanosensitive Piezo Channels in Migraine Pain

Mechanically Activated Piezo Channels Mediate Touch and Suppress Acute Mechanical Pain Response in Mice

(2019) Mingmin Zhang et al.   Cell Reports

Dietary fatty acids fine-tune Piezo1 mechanical response

(2019) Luis O. Romero et al.   Nature Communications

Nitroglycerin as a comparative experimental model of migraine pain: From animal to human and back

(2019) Chiara Demartini et al.   PROGRESS IN NEUROBIOLOGY

Calcitonin Gene‐Related Peptide Modulators – The History and Renaissance of a New Migraine Drug Class

(2019) Richard Hargreaves et al.   HEADACHE

Mechanosensitive meningeal nociception via Piezo channels: Implications for pulsatile pain in migraine?

(2019) Nikita Mikhailov et al.   NEUROPHARMACOLOGY

Meningeal Mast Cells Contribute to ATP-Induced Nociceptive Firing in Trigeminal Nerve Terminals: Direct and Indirect Purinergic Mechanisms Triggering Migraine Pain

(2019) Ksenia Koroleva et al.   Frontiers in Cellular Neuroscience

PIEZO1 Is Selectively Expressed in Small Diameter Mouse DRG Neurons Distinct From Neurons Strongly Expressing TRPV1

(2019) Jigong Wang et al.   Frontiers in Molecular Neuroscience

Mammalian Mechanoelectrical Transduction: Structure and Function of Force-Gated Ion Channels

(2019) Dominique Douguet et al.   CELL

A mechanism for the activation of the mechanosensitive Piezo1 channel by the small molecule Yoda1

(2019) Wesley M. Botello-Smith et al.   Nature Communications

Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition

(2018)   CEPHALALGIA

Structure and mechanogating mechanism of the Piezo1 channel

(2018) Qiancheng Zhao et al.   NATURE

CGRP as the target of new migraine therapies — successful translation from bench to clinic

(2018) Lars Edvinsson et al.   Nature Reviews Neurology

A lever-like transduction pathway for long-distance chemical- and mechano-gating of the mechanosensitive Piezo1 channel

(2018) Yanfeng Wang et al.   Nature Communications

Probing the gating mechanism of the mechanosensitive channel Piezo1 with the small molecule Yoda1

(2018) Jerome J. Lacroix et al.   Nature Communications

Serotonergic mechanisms of trigeminal meningeal nociception: Implications for migraine pain

(2017) Erkan Kilinc et al.   NEUROPHARMACOLOGY

Transduction of Repetitive Mechanical Stimuli by Piezo1 and Piezo2 Ion Channels

(2017) Amanda H. Lewis et al.   Cell Reports

Diversity amongst trigeminal neurons revealed by high throughput single cell sequencing

(2017) Minh Q. Nguyen et al.   PLoS One

Endothelial cation channel PIEZO1 controls blood pressure by mediating flow-induced ATP release

(2016) ShengPeng Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Nucleotide homeostasis and purinergic nociceptive signaling in rat meninges in migraine-like conditions

(2016) Gennady G. Yegutkin et al.   Purinergic Signalling

Architecture of the mammalian mechanosensitive Piezo1 channel

(2015) Jingpeng Ge et al.   NATURE

Hunting for origins of migraine pain: cluster analysis of spontaneous and capsaicin-induced firing in meningeal trigeminal nerve fibers

(2015) A. Zakharov et al.   Frontiers in Cellular Neuroscience

Chemical activation of the mechanotransduction channel Piezo1

(2015) Ruhma Syeda et al.   eLife

Piezo Proteins: Regulators of Mechanosensation and Other Cellular Processes

(2014) Sviatoslav N. Bagriantsev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Piezo2 is the major transducer of mechanical forces for touch sensation in mice

(2014) Sanjeev S. Ranade et al.   NATURE

Piezo1 integration of vascular architecture with physiological force

(2014) Jing Li et al.   NATURE

The increased distensibility of the wall of cerebral arterial network may play a role in the pathogenic mechanism of migraine headache

(2014) S. Viola et al.   NEUROLOGICAL SCIENCES

Piezo1, a mechanically activated ion channel, is required for vascular development in mice

(2014) S. S. Ranade et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

pH-Evoked Dural Afferent Signaling Is Mediated by ASIC3 and Is Sensitized by Mast Cell Mediators

(2013) Jin Yan et al.   HEADACHE

Migraine pathophysiology: Anatomy of the trigeminovascular pathway and associated neurological symptoms, cortical spreading depression, sensitization, and modulation of pain

(2013) Rodrigo Noseda et al.   PAIN

Spreading Depression Triggers Headache by Activating Neuronal Panx1 Channels

(2013) H. Karatas et al.   SCIENCE

A role for Piezo2 in EPAC1-dependent mechanical allodynia

(2013) N Eijkelkamp et al.   Nature Communications

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

Migraine pain, meningeal inflammation, and mast cells

(2009) Dan Levy   Current Pain and Headache Reports

Migraine: where and how does the pain originate?

(2009) Karl Messlinger   EXPERIMENTAL BRAIN RESEARCH

Vasoactive Intestinal Peptide Causes Marked Cephalic Vasodilation, but does not Induce Migraine

(2008) A Rahmann et al.   CEPHALALGIA

Molecular Mechanisms of Sensitization of Pain-transducing P2X3 Receptors by the Migraine Mediators CGRP and NGF

(2008) Rashid Giniatullin et al.   MOLECULAR NEUROBIOLOGY