Innate immunity to malaria—The role of monocytes

Molecular Principles of Intrauterine Growth Restriction in Plasmodium Falciparum Infection

(2019) Johanna Seitz et al.   Frontiers in Endocrinology

An Overview of Malaria in Pregnancy

(2019) Melissa Bauserman et al.   SEMINARS IN PERINATOLOGY

The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages

(2019) Julie Schulthess et al.   IMMUNITY

Adaptation and memory in immune responses

(2019) Gioacchino Natoli et al.   NATURE IMMUNOLOGY

The C-type Lectin Receptor CLEC12A Recognizes Plasmodial Hemozoin and Contributes to Cerebral Malaria Development

(2019) Marie-Kristin Raulf et al.   Cell Reports

The immune response to malaria in utero

(2019) Margaret E. Feeney   IMMUNOLOGICAL REVIEWS

Extracellular vesicles from early stage Plasmodium falciparum -infected red blood cells contain PfEMP1 and induce transcriptional changes in human monocytes

(2018) Natália G. Sampaio et al.   CELLULAR MICROBIOLOGY

Macrophage plasticity, polarization, and function in health and disease

(2018) Abbas Shapouri-Moghaddam et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cutting Edge:Plasmodium falciparumInduces Trained Innate Immunity

(2018) Jacob E. Schrum et al.   JOURNAL OF IMMUNOLOGY

Remembering Pathogen Dose: Long-Term Adaptation in Innate Immunity

(2018) Michael Bauer et al.   TRENDS IN IMMUNOLOGY

Hemozoin-induced activation of human monocytes toward M2-like phenotype is partially reversed by antimalarial drugs-chloroquine and artemisinin

(2018) Deepali Bobade et al.   MicrobiologyOpen

Soluble markers of neutrophil, T-cell and monocyte activation are associated with disease severity and parasitemia in falciparum malaria

(2018) Kari Otterdal et al.   BMC INFECTIOUS DISEASES

Monocyte phagocytosis of malaria β-haematin in the presence of artemisinin, amodiaquine, chloroquine, doxycycline, primaquine, pyrimethamine and quinine

(2018) Bridgette M. Cumming et al.   EXPERIMENTAL PARASITOLOGY

Correlation of malaria parasitaemia with peripheral blood monocyte to lymphocyte ratio as indicator of susceptibility to severe malaria in Ghanaian children

(2018) Samuel Antwi-Baffour et al.   MALARIA JOURNAL

Organ-Specific Fate, Recruitment, and Refilling Dynamics of Tissue-Resident Macrophages during Blood-Stage Malaria

(2018) Si Min Lai et al.   Cell Reports

Microvesicles from malaria-infected red blood cells activate natural killer cells via MDA5 pathway

(2018) Weijian Ye et al.   PLoS Pathogens

Parasite Recognition and Signaling Mechanisms in Innate Immune Responses to Malaria

(2018) D. Channe Gowda et al.   Frontiers in Immunology

Interplay of extracellular vesicles and other players in cerebral malaria pathogenesis

(2018) Sophie Debs et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Epigenetic landscapes underlining global patterns of gene expression in the human malaria parasite, Plasmodium falciparum

(2017) Archana P Gupta et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Cyclic GMP–AMP Synthase Is the Cytosolic Sensor ofPlasmodium falciparumGenomic DNA and Activates Type I IFN in Malaria

(2017) Carolina Gallego-Marin et al.   JOURNAL OF IMMUNOLOGY

The role of extracellular vesicles in malaria biology and pathogenesis

(2017) Natalia Guimaraes Sampaio et al.   MALARIA JOURNAL

Protective vaccination and blood-stage malaria modify DNA methylation of gene promoters in the liver of Balb/c mice

(2017) Saleh Al-Quraishy et al.   PARASITOLOGY RESEARCH

Malaria parasite DNA-harbouring vesicles activate cytosolic immune sensors

(2017) Xavier Sisquella et al.   Nature Communications

Rewiring monocyte glucose metabolism via C-type lectin signaling protects against disseminated candidiasis

(2017) Jorge Domínguez-Andrés et al.   PLoS Pathogens

Interaction between Plasmodium Glycosylphosphatidylinositol and the Host Protein Moesin Has No Implication in Malaria Pathology

(2017) Josefine Dunst et al.   Frontiers in Cellular and Infection Microbiology

Epigenetic Regulation of Monocyte and Macrophage Function

(2016) Marten A. Hoeksema et al.   ANTIOXIDANTS & REDOX SIGNALING

Genetic Ancestry and Natural Selection Drive Population Differences in Immune Responses to Pathogens

(2016) Yohann Nédélec et al.   CELL

Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity

(2016) Rob J.W. Arts et al.   Cell Metabolism

Rewiring cellular metabolism via the AKT/mTOR pathway contributes to host defence againstMycobacterium tuberculosisin human and murine cells

(2016) Ekta Lachmandas et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Tissue-Resident Macrophage Ontogeny and Homeostasis

(2016) Florent Ginhoux et al.   IMMUNITY

Epigenetics and innate immunity: the ‘unTolld’ story

(2016) Conor Hennessy et al.   IMMUNOLOGY AND CELL BIOLOGY

Immune response pattern in recurrent Plasmodium vivax malaria

(2016) Yury Oliveira Chaves et al.   MALARIA JOURNAL

The development and maintenance of resident macrophages

(2016) Elisa Gomez Perdiguero et al.   NATURE IMMUNOLOGY

Monocyte activation and cytokine production in Malawian children presenting with P. falciparum malaria

(2016) W. L. Mandala et al.   PARASITE IMMUNOLOGY

Immunometabolic circuits in trained immunity

(2016) Rob J.W. Arts et al.   SEMINARS IN IMMUNOLOGY

Infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria

(2016) Pierre-Yves Mantel et al.   Nature Communications

Tissue-Resident CD169 + Macrophages Form a Crucial Front Line against Plasmodium Infection

(2016) Pravesh Gupta et al.   Cell Reports

Immunometabolic Pathways in BCG-Induced Trained Immunity

(2016) Rob J.W. Arts et al.   Cell Reports

Microbial stimulation of different Toll-like receptor signalling pathways induces diverse metabolic programmes in human monocytes

(2016) Ekta Lachmandas et al.   Nature Microbiology

Monocyte polarization in children with falciparum malaria: relationship to nitric oxide insufficiency and disease severity

(2016) J. Brice Weinberg et al.   Scientific Reports

Macrophages: Development and Tissue Specialization

(2015) Chen Varol et al.   Annual Review of Immunology

CD14hiCD16+ monocytes phagocytose antibody-opsonised Plasmodium falciparum infected erythrocytes more efficiently than other monocyte subsets, and require CD16 and complement to do so

(2015) Jingling Zhou et al.   BMC Medicine

Metabolic reprogramming in macrophages and dendritic cells in innate immunity

(2015) Beth Kelly et al.   CELL RESEARCH

Bacterial infection remodels the DNA methylation landscape of human dendritic cells

(2015) Alain Pacis et al.   GENOME RESEARCH

Most Tissue-Resident Macrophages Except Microglia Are Derived from Fetal Hematopoietic Stem Cells

(2015) Jianpeng Sheng et al.   IMMUNITY

Liver-Resident Macrophage Necroptosis Orchestrates Type 1 Microbicidal Inflammation and Type-2-Mediated Tissue Repair during Bacterial Infection

(2015) Camille Blériot et al.   IMMUNITY

Human Monocytes Undergo Functional Re-programming during Sepsis Mediated by Hypoxia-Inducible Factor-1α

(2015) Irina N. Shalova et al.   IMMUNITY

Plasmodium falciparum Infection of Human Volunteers Activates Monocytes and CD16+Dendritic Cells and Induces Upregulation of CD16 and CD1c Expression

(2015) Anne C. Teirlinck et al.   INFECTION AND IMMUNITY

Immunometabolism governs dendritic cell and macrophage function

(2015) Luke A.J. O’Neill et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Differentiation Kinetics of Blood Monocytes and Dendritic Cells in Macaques: Insights to Understanding Human Myeloid Cell Development

(2015) Chie Sugimoto et al.   JOURNAL OF IMMUNOLOGY

Human C1-Inhibitor Suppresses Malaria Parasite Invasion and Cytoadhesion via Binding to Parasite Glycosylphosphatidylinositol and Host Cell Receptors

(2015) Pedro Mejia et al.   JOURNAL OF INFECTIOUS DISEASES

Recruited monocytes modulate malaria-induced lung injury through CD36-mediated clearance of sequestered infected erythrocytes

(2015) H. A. Daniel Lagassé et al.   JOURNAL OF LEUKOCYTE BIOLOGY

DNA-Containing Immunocomplexes Promote Inflammasome Assembly and Release of Pyrogenic Cytokines by CD14+ CD16+ CD64high CD32low Inflammatory Monocytes from Malaria Patients

(2015) I. C. Hirako et al.   mBio

Fatal Pediatric Cerebral Malaria Is Associated with Intravascular Monocytes and Platelets That Are Increased with HIV Coinfection

(2015) Sarah E. Hochman et al.   mBio

Impaired Systemic Tetrahydrobiopterin Bioavailability and Increased Oxidized Biopterins in Pediatric Falciparum Malaria: Association with Disease Severity

(2015) Matthew P. Rubach et al.   PLoS Pathogens

Impaired Systemic Tetrahydrobiopterin Bioavailability and Increased Dihydrobiopterin in Adult Falciparum Malaria: Association with Disease Severity, Impaired Microvascular Function and Increased Endothelial Activation

(2015) Tsin W. Yeo et al.   PLoS Pathogens

Monocyte homeostasis and the plasticity of inflammatory monocytes

(2014) Andrew J. Mitchell et al.   CELLULAR IMMUNOLOGY

The role of extracellular vesicles inPlasmodiumand other protozoan parasites

(2014) Pierre-Yves Mantel et al.   CELLULAR MICROBIOLOGY

Exosomes and other extracellular vesicles in host-pathogen interactions

(2014) J. S. Schorey et al.   EMBO REPORTS

Metabolic Reprogramming of Macrophages

(2014) Alex J. Freemerman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Monocarboxylate Transporter 4 Is Required for Glycolytic Reprogramming and Inflammatory Response in Macrophages

(2014) Zheng Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BAFF and BAFF Receptor Levels Correlate with B Cell Subset Activation and Redistribution in Controlled Human Malaria Infection

(2014) A. Scholzen et al.   JOURNAL OF IMMUNOLOGY

γδ T cells and CD14+ Monocytes Are Predominant Cellular Sources of Cytokines and Chemokines Associated With Severe Malaria

(2014) Danielle I. Stanisic et al.   JOURNAL OF INFECTIOUS DISEASES

Dimethylarginines: Endogenous Inhibitors of Nitric Oxide Synthesis in Children With Falciparum Malaria

(2014) Joe Brice Weinberg et al.   JOURNAL OF INFECTIOUS DISEASES

The association between malaria and non-typhoid Salmonella bacteraemia in children in sub-Saharan Africa: a literature review

(2014) Ebako Takem et al.   MALARIA JOURNAL

Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice

(2014) Calum C Bain et al.   NATURE IMMUNOLOGY

TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation

(2014) Bart Everts et al.   NATURE IMMUNOLOGY

Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity

(2014) S. Saeed et al.   SCIENCE

Plasmodium falciparum transmission stages accumulate in the human bone marrow

(2014) R. Joice et al.   Science Translational Medicine

Dual Engagement of the NLRP3 and AIM2 Inflammasomes by Plasmodium-Derived Hemozoin and DNA during Malaria

(2014) Parisa Kalantari et al.   Cell Reports

The CD14+CD16+ Inflammatory Monocyte Subset Displays Increased Mitochondrial Activity and Effector Function During Acute Plasmodium vivax Malaria

(2014) Lis R. V. Antonelli et al.   PLoS Pathogens

Metabolism via Arginase or Nitric Oxide Synthase: Two Competing Arginine Pathways in Macrophages

(2014) Meera Rath et al.   Frontiers in Immunology

Malarial Pigment Hemozoin and the Innate Inflammatory Response

(2014) Martin Olivier et al.   Frontiers in Immunology

Peripheral blood monocyte-to-lymphocyte ratio at study enrollment predicts efficacy of the RTS,S malaria vaccine: analysis of pooled phase II clinical trial data

(2013) George M Warimwe et al.   BMC Medicine

Malaria-Infected Erythrocyte-Derived Microvesicles Mediate Cellular Communication within the Parasite Population and with the Host Immune System

(2013) Pierre-Yves Mantel et al.   Cell Host & Microbe

Toll-Like Receptor 7 Mediates Early Innate Immune Responses to Malaria

(2013) Alyssa Baccarella et al.   INFECTION AND IMMUNITY

A histological method for quantifying Plasmodium falciparum in the brain in fatal paediatric cerebral malaria

(2013) Danny A Milner et al.   MALARIA JOURNAL

Tissue-resident macrophages

(2013) Luke C Davies et al.   NATURE IMMUNOLOGY

Extracellular vesicles: biology and emerging therapeutic opportunities

(2013) Samir EL Andaloussi et al.   NATURE REVIEWS DRUG DISCOVERY

Mortality Patterns and Site Heterogeneity of Severe Malaria in African Children

(2013) Eric Kendjo et al.   PLoS One

Soluble CD163, a Product of Monocyte/Macrophage Activation, Is Inversely Associated with Haemoglobin Levels in Placental Malaria

(2013) Caroline Lin Lin Chua et al.   PLoS One

Programming of DNA Methylation Patterns

(2012) Howard Cedar et al.   Annual Review of Biochemistry

Estimating physical splenic filtration ofPlasmodium falciparum-infected red blood cells in malaria patients

(2012) Thurston Herricks et al.   CELLULAR MICROBIOLOGY

The three human monocyte subsets: implications for health and disease

(2012) Kok Loon Wong et al.   IMMUNOLOGIC RESEARCH

Epigenetic Dysregulation of Virulence Gene Expression in Severe Plasmodium falciparum Malaria

(2012) Catherine J. Merrick et al.   JOURNAL OF INFECTIOUS DISEASES

Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium

(2012) Nirmal Robinson et al.   NATURE IMMUNOLOGY

Functions of DNA methylation: islands, start sites, gene bodies and beyond

(2012) Peter A. Jones   NATURE REVIEWS GENETICS

Erasing the Epigenetic Memory and Beginning to Switch—The Onset of Antigenic Switching of var Genes in Plasmodium falciparum

(2012) Yair Fastman et al.   PLoS One

Bacille Calmette-Guerin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes

(2012) J. Kleinnijenhuis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Monocytes and macrophages in malaria: protection or pathology?

(2012) Caroline Lin Lin Chua et al.   TRENDS IN PARASITOLOGY

Neutrophil Paralysis in Plasmodium vivax Malaria

(2012) Fabiana Maria de Souza Leoratti et al.   PLoS Neglected Tropical Diseases

Host fibrinogen stably bound to hemozoin rapidly activates monocytes via TLR-4 and CD11b/CD18-integrin: a new paradigm of hemozoin action

(2011) V. Barrera et al.   BLOOD

Trained Immunity: A Memory for Innate Host Defense

(2011) Mihai G. Netea et al.   Cell Host & Microbe

Immunopathogenesis of falciparum malaria: implications for adjunctive therapy in the management of severe and cerebral malaria

(2011) Sarah J Higgins et al.   Expert Review of Anti-Infective Therapy

Innate Immune Recognition of an AT-Rich Stem-Loop DNA Motif in the Plasmodium falciparum Genome

(2011) Shruti Sharma et al.   IMMUNITY

Role of Interleukin-10 in Malaria: Focusing on Coinfection with Lethal and Nonlethal Murine Malaria Parasites

(2011) Mamoru Niikura et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Circulating Red Cell–derived Microparticles in Human Malaria

(2011) Duangdao Nantakomol et al.   JOURNAL OF INFECTIOUS DISEASES

Therapeutic blockade of PD-L1 and LAG-3 rapidly clears established blood-stage Plasmodium infection

(2011) Noah S Butler et al.   NATURE IMMUNOLOGY

The Nucleosome (Histone-DNA Complex) Is the TLR9-Specific Immunostimulatory Component of Plasmodium falciparum That Activates DCs

(2011) Nagaraj M. Gowda et al.   PLoS One

Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation

(2010) C. M. Krawczyk et al.   BLOOD

Complement driven innate immune response to malaria: fuelling severe malarial diseases

(2010) Karlee L. Silver et al.   CELLULAR MICROBIOLOGY

Correlation analysis of intracellular and secreted cytokines via the generalized integrated mean fluorescence intensity

(2010) Parisa Shooshtari et al.   CYTOMETRY PART A

The Levels of CD16/Fc  Receptor IIIA on CD14+ CD16+ Monocytes Are Higher in Children with Severe Plasmodium falciparum Anemia than in Children with Cerebral or Uncomplicated Malaria

(2010) L. A. Ogonda et al.   INFECTION AND IMMUNITY

Substrate Fate in Activated Macrophages: A Comparison between Innate, Classic, and Alternative Activation

(2010) J.-C. Rodriguez-Prados et al.   JOURNAL OF IMMUNOLOGY

Protein-DNA Complex Is the Exclusive Malaria Parasite Component That Activates Dendritic Cells and Triggers Innate Immune Responses

(2010) X. Wu et al.   JOURNAL OF IMMUNOLOGY

Augmented plasma microparticles during acute Plasmodium vivax infection

(2010) Fernanda MF Campos et al.   MALARIA JOURNAL

Innate inflammatory response to the malarial pigment hemozoin

(2010) Marina T. Shio et al.   MICROBES AND INFECTION

Elevated Cell-Specific Microparticles Are a Biological Marker for Cerebral Dysfunctions in Human Severe Malaria

(2010) Joël Bertrand Pankoui Mfonkeu et al.   PLoS One

Parasite-Derived Plasma Microparticles Contribute Significantly to Malaria Infection-Induced Inflammation through Potent Macrophage Stimulation

(2010) Kevin N. Couper et al.   PLoS Pathogens

Migrating monocytes recruited to the spleen play an important role in control of blood stage malaria

(2009) A.-M. Sponaas et al.   BLOOD

HIV Infection, Malnutrition, and Invasive Bacterial Infection among Children with Severe Malaria

(2009) James A. Berkley et al.   CLINICAL INFECTIOUS DISEASES

Acquired Immunity to Malaria

(2009) D. L. Doolan et al.   CLINICAL MICROBIOLOGY REVIEWS

Experimental cerebral malaria progresses independently of the Nlrp3 inflammasome

(2009) Thornik Reimer et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

MAPK-activated Protein Kinase 2 Differentially RegulatesPlasmodium falciparumGlycosylphosphatidylinositol-induced Production of Tumor Necrosis Factor-α and Interleukin-12 in Macrophages

(2009) Jianzhong Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selection of Molecular Structure and Delivery of RNA Oligonucleotides to Activate TLR7 versus TLR8 and to Induce High Amounts of IL-12p70 in Primary Human Monocytes

(2009) A. Ablasser et al.   JOURNAL OF IMMUNOLOGY

The C-Type Lectin Clec12A Present on Mouse and Human Dendritic Cells Can Serve as a Target for Antigen Delivery and Enhancement of Antibody Responses

(2009) M. H. Lahoud et al.   JOURNAL OF IMMUNOLOGY

TLR8-driven IL-12–dependent Reciprocal and Synergistic Activation of NK Cells and Monocytes by Immunostimulatory RNA

(2009) Michael Berger et al.   JOURNAL OF IMMUNOTHERAPY

CCR2 and CXCR4 regulate peripheral blood monocyte pharmacodynamics and link to efficacy in experimental autoimmune encephalomyelitis

(2009) Yuanfan Wang et al.   Journal of Inflammation-London

Malarial Hemozoin Is a Nalp3 Inflammasome Activating Danger Signal

(2009) Catherine Dostert et al.   PLoS One

Malaria primes the innate immune response due to interferon-  induced enhancement of toll-like receptor expression and function

(2009) B. S. Franklin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Distinct Peripheral Blood Monocyte Phenotype Is Associated with Parasite Inhibitory Activity in Acute Uncomplicated Plasmodium falciparum Malaria

(2009) Pattamawan Chimma et al.   PLoS Pathogens

Malarial Hemozoin Activates the NLRP3 Inflammasome through Lyn and Syk Kinases

(2009) Marina Tiemi Shio et al.   PLoS Pathogens

Accessing the therapeutic potential of immunostimulatory nucleic acids

(2008) Winfried Barchet et al.   CURRENT OPINION IN IMMUNOLOGY

Receptor-Independent, Direct Membrane Binding Leads to Cell-Surface Lipid Sorting and Syk Kinase Activation in Dendritic Cells

(2008) Gilbert Ng et al.   IMMUNITY

3. Adhesion molecules and receptors

(2008) C SMITH   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Immunologic activation of human syncytiotrophoblast by Plasmodium falciparum

(2008) Naomi W Lucchi et al.   MALARIA JOURNAL

Expression of Toll-like receptors on antigen-presenting cells in patients with falciparum malaria

(2007) Somying Loharungsikul et al.   ACTA TROPICA