Impaired Systemic Tetrahydrobiopterin Bioavailability and Increased Dihydrobiopterin in Adult Falciparum Malaria: Association with Disease Severity, Impaired Microvascular Function and Increased Endothelial Activation
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Title
Impaired Systemic Tetrahydrobiopterin Bioavailability and Increased Dihydrobiopterin in Adult Falciparum Malaria: Association with Disease Severity, Impaired Microvascular Function and Increased Endothelial Activation
Authors
Keywords
Malaria, Nitric oxide, Phenylalanine, Creatinine, Metabolites, Urine, Malarial parasites, Severe sepsis
Journal
PLoS Pathogens
Volume 11, Issue 3, Pages e1004667
Publisher
Public Library of Science (PLoS)
Online
2015-03-13
DOI
10.1371/journal.ppat.1004667
References
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Related references
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- N-acetylcysteine as adjunctive treatment in severe malaria: A randomized, double-blinded placebo-controlled clinical trial*
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- Critical Role for Tetrahydrobiopterin Recycling by Dihydrofolate Reductase in Regulation of Endothelial Nitric-oxide Synthase Coupling
- (2009) Mark J. Crabtree et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Relationship of Cell‐Free Hemoglobin to Impaired Endothelial Nitric Oxide Bioavailability and Perfusion in Severe Falciparum Malaria
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- (2009) Nicola Longo JOURNAL OF INHERITED METABOLIC DISEASE
- Malaria morbidity in Papua Indonesia, an area with multidrug resistant Plasmodium vivax and Plasmodium falciparum
- (2008) Muhammad Karyana et al. MALARIA JOURNAL
- Angiopoietin-2 is associated with decreased endothelial nitric oxide and poor clinical outcome in severe falciparum malaria
- (2008) T. W. Yeo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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