RvE1 treatment prevents memory loss and neuroinflammation in the Ts65Dn mouse model of Down syndrome

Combined administration of resolvin E1 and lipoxin A4 resolves inflammation in a murine model of Alzheimer's disease

(2018) Alpdogan Kantarci et al.   EXPERIMENTAL NEUROLOGY

Exosomal biomarkers in Down syndrome and Alzheimer's disease

(2018) Eric D. Hamlett et al.   FREE RADICAL BIOLOGY AND MEDICINE

Resolvin E1 (Rv E1 ) attenuates LPS induced inflammation and subsequent atrophy in C2C12 myotubes

(2018) Luke A. Baker et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Neuronal SphK1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer’s Disease

(2018) Ju Youn Lee et al.   Nature Communications

A Noradrenergic Lesion Exacerbates Neurodegeneration in a Down Syndrome Mouse Model

(2018) Jason Lockrow et al.   JOURNAL OF ALZHEIMERS DISEASE

Probing the intermolecular interactions of PPARγ-LBD with polyunsaturated fatty acids and their anti-inflammatory metabolites to infer most potential binding moieties

(2017) Shalini Muralikumar et al.   Lipids in Health and Disease

Aberrations in circulating inflammatory cytokine levels in patients with Down syndrome: a meta-analysis

(2017) Yan Zhang et al.   Oncotarget

An inflammatory and trophic disconnect biomarker profile revealed in Down syndrome plasma: Relation to cognitive decline and longitudinal evaluation

(2016) M. Florencia Iulita et al.   Alzheimers & Dementia

Resolvin D1 and E1 promote resolution of inflammation in microglial cells in vitro

(2016) C. Rey et al.   BRAIN BEHAVIOR AND IMMUNITY

The contribution of the citrate pathway to oxidative stress in Down syndrome

(2016) Paolo Convertini et al.   IMMUNOLOGY

Resolution of inflammation is altered in Alzheimer's disease

(2015) Xiuzhe Wang et al.   Alzheimers & Dementia

Cognitive Impairment, Neuroimaging, and Alzheimer Neuropathology in Mouse Models of Down Syndrome

(2015) Eric D. Hamlett et al.   Current Alzheimer Research

Aging in Down Syndrome and the Development of Alzheimer's Disease Neuropathology

(2015) Elizabeth Head et al.   Current Alzheimer Research

Designer Receptors Enhance Memory in a Mouse Model of Down Syndrome

(2015) A. M. Fortress et al.   JOURNAL OF NEUROSCIENCE

PPAR-γ Ameliorates Neuronal Apoptosis and Ischemic Brain Injury via Suppressing NF-κB-Driven p22phox Transcription

(2015) Jui-Sheng Wu et al.   MOLECULAR NEUROBIOLOGY

Pro-Resolving Lipid Mediators Improve Neuronal Survival and Increase Aβ42 Phagocytosis

(2015) Mingqin Zhu et al.   MOLECULAR NEUROBIOLOGY

Down syndrome individuals with Alzheimer's disease have a distinct neuroinflammatory phenotype compared to sporadic Alzheimer's disease

(2015) Donna M. Wilcock et al.   NEUROBIOLOGY OF AGING

Increased Mammalian Target of Rapamycin Signaling Contributes to the Accumulation of Protein Oxidative Damage in a Mouse Model of Down's Syndrome

(2015) Antonella Tramutola et al.   Neurodegenerative Diseases

Long-chain omega-3 fatty acids and the brain: a review of the independent and shared effects of EPA, DPA and DHA

(2015) Simon C. Dyall   Frontiers in Aging Neuroscience

Curcumin Improves Amyloid β-Peptide (1-42) Induced Spatial Memory Deficits through BDNF-ERK Signaling Pathway

(2015) Lu Zhang et al.   PLoS One

Neuropathological role of PI3K/Akt/mTOR axis in Down syndrome brain

(2014) Marzia Perluigi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Proresolving Lipid Mediators and Mechanisms in the Resolution of Acute Inflammation

(2014) Christopher D. Buckley et al.   IMMUNITY

mTOR Hyperactivation in Down Syndrome Hippocampus Appears Early During Development

(2014) Anand M. Iyer et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Resolvin E1 promotes resolution of inflammation in a mouse model of an acute exacerbation of allergic asthma

(2013) Rylie P. Flesher et al.   CLINICAL SCIENCE

Protein profiles in Tc1 mice implicate novel pathway perturbations in the Down syndrome brain

(2013) M. M. Ahmed et al.   HUMAN MOLECULAR GENETICS

Cytokine and Chemokine Alterations in Down Syndrome

(2012) Robin Roberson et al.   AMERICAN JOURNAL OF PERINATOLOGY

Mouse Models of Down Syndrome as a Tool to Unravel the Causes of Mental Disabilities

(2012) Noemí Rueda et al.   NEURAL PLASTICITY

Impact and Therapeutic Potential of PPARs in Alzheimers Disease

(2011) Michael T. Heneka et al.   Current Neuropharmacology

Docosahexaenoic Acid-Derived Neuroprotectin D1 Induces Neuronal Survival via Secretase- and PPARγ-Mediated Mechanisms in Alzheimer's Disease Models

(2011) Yuhai Zhao et al.   PLoS One

Resolvin E1 protects the rat heart against reperfusion injury

(2010) K. T. Keyes et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Effects of long-term memantine on memory and neuropathology in Ts65Dn mice, a model for Down syndrome

(2010) Jason Lockrow et al.   BEHAVIOURAL BRAIN RESEARCH

Lipoxin A4 impairment of apoptotic signaling in macrophages: implication of the PI3K/Akt and the ERK/Nrf-2 defense pathways

(2010) P Prieto et al.   CELL DEATH AND DIFFERENTIATION

Cholinergic degeneration and memory loss delayed by vitamin E in a Down syndrome mouse model

(2008) Jason Lockrow et al.   EXPERIMENTAL NEUROLOGY