PPAR-γ Ameliorates Neuronal Apoptosis and Ischemic Brain Injury via Suppressing NF-κB-Driven p22phox Transcription

NADPH Oxidase-2: Linking Glucose, Acidosis, and Excitotoxicity in Stroke

(2015) Angela M. Brennan-Minnella et al.   ANTIOXIDANTS & REDOX SIGNALING

Nox family NADPH oxidases: Molecular mechanisms of activation

(2014) Ralf P. Brandes et al.   FREE RADICAL BIOLOGY AND MEDICINE

Novel Link of Anti-apoptotic ATF3 with Pro-apoptotic CTMP in the Ischemic Brain

(2014) Chien-Yu Huang et al.   MOLECULAR NEUROBIOLOGY

HDAC4/5-HMGB1 signalling mediated by NADPH oxidase activity contributes to cerebral ischaemia/reperfusion injury

(2013) Min He et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

15-Deoxy-∆12,14-PGJ2, by Activating Peroxisome Proliferator-Activated Receptor-Gamma, Suppresses p22phox Transcription to Protect Brain Endothelial Cells Against Hypoxia-Induced Apoptosis

(2013) Jui-Sheng Wu et al.   MOLECULAR NEUROBIOLOGY

Association between NADPH Oxidase p22phox C242T Polymorphism and Ischemic Cerebrovascular Disease: A Meta-Analysis

(2013) Bing-Hu Li et al.   PLoS One

Neuroprotection After Stroke by Targeting NOX4 As a Source of Oxidative Stress

(2012) Kim A. Radermacher et al.   ANTIOXIDANTS & REDOX SIGNALING

Which NADPH Oxidase Isoform Is Relevant for Ischemic Stroke? The Case for Nox 2

(2012) Timo Kahles et al.   ANTIOXIDANTS & REDOX SIGNALING

NADPH oxidases as therapeutic targets in ischemic stroke

(2012) Timo Kahles et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

NADPH oxidases as a source of oxidative stress and molecular target in ischemia/reperfusion injury

(2012) Pamela W. M. Kleikers et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Suppression of the inflammatory response by diphenyleneiodonium after transient focal cerebral ischemia

(2012) Simon Nagel et al.   JOURNAL OF NEUROCHEMISTRY

Peroxisome Proliferator-Activated Receptor Gamma (PPAR-γ) and Neurodegenerative Disorders

(2012) Yu-Chang Chen et al.   MOLECULAR NEUROBIOLOGY

NADPH oxidase in stroke and cerebrovascular disease

(2012) Xian Nan Tang et al.   NEUROLOGICAL RESEARCH

Nifedipine Activates PPARγ and Exerts Antioxidative Action Through Cu/ZnSOD Independent of Blood-pressure Lowering in SHRSP

(2011) Ryo Hashimoto et al.   Journal of Atherosclerosis and Thrombosis

Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets

(2011) Grant R. Drummond et al.   NATURE REVIEWS DRUG DISCOVERY

NADPH oxidase is involved in post-ischemic brain inflammation

(2011) Hai Chen et al.   NEUROBIOLOGY OF DISEASE

Oxidative Stress in Ischemic Brain Damage: Mechanisms of Cell Death and Potential Molecular Targets for Neuroprotection

(2010) Hai Chen et al.   ANTIOXIDANTS & REDOX SIGNALING

Get With The Guidelines-Stroke Performance Indicators: Surveillance of Stroke Care in the Taiwan Stroke Registry

(2010) Fang-I Hsieh et al.   CIRCULATION

Anti-apoptotic Actions of PPAR-γ Against Ischemic Stroke

(2010) Wen-Hsuan Fong et al.   MOLECULAR NEUROBIOLOGY

NADPH oxidase Nox1 contributes to ischemic injury in experimental stroke in mice

(2010) Timo Kahles et al.   NEUROBIOLOGY OF DISEASE

The Science of Stroke: Mechanisms in Search of Treatments

(2010) Michael A. Moskowitz et al.   NEURON

Neuroprotective effects of pioglitazone in a rat model of permanent focal cerebral ischemia are associated with peroxisome proliferator-activated receptor gamma-mediated suppression of nuclear factor-κB signaling pathway

(2010) H.-L. Zhang et al.   NEUROSCIENCE

Post-Stroke Inhibition of Induced NADPH Oxidase Type 4 Prevents Oxidative Stress and Neurodegeneration

(2010) Christoph Kleinschnitz et al.   PLOS BIOLOGY

Treatment of spontaneously hypertensive rats with rosiglitazone ameliorates cardiovascular pathophysiology via antioxidant mechanisms in the vasculature

(2009) Maria A. Potenza et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The Role of Ubiquitin in NF-κB Regulatory Pathways

(2009) Brian Skaug et al.   Annual Review of Biochemistry

Reduction of cerebral infarct volume by apocynin requires pretreatment and is absent in Nox2-deficient mice

(2009) KA Jackman et al.   BRITISH JOURNAL OF PHARMACOLOGY

Ligand-Activated Peroxisome Proliferator–Activated Receptor-γ Protects Against Ischemic Cerebral Infarction and Neuronal Apoptosis by 14-3-3ε Upregulation

(2009) Jui-Sheng Wu et al.   CIRCULATION

Heart Disease and Stroke Statistics—2010 Update

(2009) et al.   CIRCULATION

Rosiglitazone and PPAR-γ overexpression protect mitochondrial membrane potential and prevent apoptosis by upregulating anti-apoptotic Bcl-2 family proteins

(2009) Jui-Sheng Wu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Inhibition of NADPH Oxidase is Neuroprotective after Ischemia—Reperfusion

(2009) Hai Chen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neuronal PPAR  Deficiency Increases Susceptibility to Brain Damage after Cerebral Ischemia

(2009) X. Zhao et al.   JOURNAL OF NEUROSCIENCE

NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation

(2009) Angela M Brennan et al.   NATURE NEUROSCIENCE

Glucose and NADPH oxidase drive neuronal superoxide formation in stroke

(2008) Sang Won Suh et al.   ANNALS OF NEUROLOGY

Peroxisome Proliferator-Activated Receptor-γ (PPAR-γ) Ligands: Novel Pharmacological Agents in the Treatment of Ischemia Reperfusion Injury

(2008) Costas Giaginis et al.   CURRENT MOLECULAR MEDICINE

Rescue of Neurons from Ischemic Injury by Peroxisome Proliferator-Activated Receptor-  Requires a Novel Essential Cofactor LMO4

(2008) S. C. Schock et al.   JOURNAL OF NEUROSCIENCE

Mechanisms of anti-inflammatory and neuroprotective actions of PPAR-gamma agonists

(2007) Ramya Kapadia   Frontiers in Bioscience-Landmark