Myelin and oligodendrocyte lineage cell dysfunctions: New players in the etiology and treatment of depression and stress‐related disorders

Low‐intensity transcranial magnetic stimulation promotes the survival and maturation of newborn oligodendrocytes in the adult mouse brain

(2019) Carlie L. Cullen et al.   GLIA

Altered Connectivity in Depression: GABA and Glutamate Neurotransmitter Deficits and Reversal by Novel Treatments

(2019) Ronald S. Duman et al.   NEURON

Oligodendrocytes regulate presynaptic properties and neurotransmission through BDNF signaling in the mouse brainstem

(2019) Miae Jang et al.   eLife

Venlafaxine Improves the Cognitive Impairment and Depression-Like Behaviors in a Cuprizone Mouse Model by Alleviating Demyelination and Neuroinflammation in the Brain

(2019) Yanbo Zhang et al.   Frontiers in Pharmacology

The effects of running exercise on oligodendrocytes in the hippocampus of rats with depression induced by chronic unpredictable stress

(2019) Jing Tang et al.   BRAIN RESEARCH BULLETIN

Psychiatric Genomics: An Update and an Agenda

(2018) Patrick F. Sullivan et al.   AMERICAN JOURNAL OF PSYCHIATRY

Opposite Molecular Signatures of Depression in Men and Women

(2018) Marianne L. Seney et al.   BIOLOGICAL PSYCHIATRY

Axonal myelin decrease in the splenium in major depressive disorder

(2018) Matthew R. Williams et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Gene-environment interactions between stress and 5-HTTLPR in depression: A meta-analytic update

(2018) Dries Bleys et al.   JOURNAL OF AFFECTIVE DISORDERS

BDNF Val66Met polymorphism, life stress and depression: A meta-analysis of gene-environment interaction

(2018) Mingzhe Zhao et al.   JOURNAL OF AFFECTIVE DISORDERS

Association between abnormal serum myelin-specific protein levels and white matter integrity in first-episode and drug-naïve patients with major depressive disorder

(2018) Linling Jiang et al.   JOURNAL OF AFFECTIVE DISORDERS

Myelin remodeling through experience-dependent oligodendrogenesis in the adult somatosensory cortex

(2018) Ethan G. Hughes et al.   NATURE NEUROSCIENCE

Lifelong cortical myelin plasticity and age-related degeneration in the live mammalian brain

(2018) Robert A. Hill et al.   NATURE NEUROSCIENCE

Absence of Claudin 11 in CNS Myelin Perturbs Behavior and Neurotransmitter Levels in Mice

(2018) Kathleen J. Maheras et al.   Scientific Reports

Oligodendrocytes control potassium accumulation in white matter and seizure susceptibility

(2018) Valerie A Larson et al.   eLife

Regulation of Central Nervous System Myelination in Higher Brain Functions

(2018) Mara Nickel et al.   NEURAL PLASTICITY

The Influence of Myelin Oligodendrocyte Glycoprotein on White Matter Abnormalities in Different Onset Age of Drug-Naïve Depression

(2018) Feng Wu et al.   Frontiers in Psychiatry

Oligodendrocyte-encoded Kir4.1 function is required for axonal integrity

(2018) Lucas Schirmer et al.   eLife

How Do Cells of the Oligodendrocyte Lineage Affect Neuronal Circuits to Influence Motor Function, Memory and Mood?

(2018) Renee E. Pepper et al.   Frontiers in Cellular Neuroscience

Switching of the Microglial Activation Phenotype Is a Possible Treatment for Depression Disorder

(2018) Lijuan Zhang et al.   Frontiers in Cellular Neuroscience

Changes in white matter and the effects of fluoxetine on such changes in the CUS rat model of depression

(2018) Yuan Gao et al.   NEUROSCIENCE LETTERS

Deep brain stimulation targets for treating depression

(2018) Dominik Drobisz et al.   BEHAVIOURAL BRAIN RESEARCH

Lineage tracing reveals dynamic changes in oligodendrocyte precursor cells following cuprizone-induced demyelination

(2017) Emily G. Baxi et al.   GLIA

Pharmacological treatment of unipolar depressive disorders: summary of WFSBP guidelines

(2017) Michael Bauer et al.   INTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICE

Oligodendroglia: metabolic supporters of neurons

(2017) Thomas Philips et al.   JOURNAL OF CLINICAL INVESTIGATION

Exercise protects myelinated fibers of white matter in a rat model of depression

(2017) Qian Xiao et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Myelinogenic Plasticity of Oligodendrocyte Precursor Cells following Spinal Cord Contusion Injury

(2017) Peggy Assinck et al.   JOURNAL OF NEUROSCIENCE

Microstructural brain abnormalities in medication-free patients with major depressive disorder: a systematic review and meta-analysis of diffusion tensor imaging

(2017) Jing Jiang et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Child abuse associates with an imbalance of oligodendrocyte-lineage cells in ventromedial prefrontal white matter

(2017) A Tanti et al.   MOLECULAR PSYCHIATRY

Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression

(2017) R C Culverhouse et al.   MOLECULAR PSYCHIATRY

Sex-specific transcriptional signatures in human depression

(2017) Benoit Labonté et al.   NATURE MEDICINE

Brain-derived neurotrophic factor in mood disorders and antidepressant treatments

(2017) Eero Castrén et al.   NEUROBIOLOGY OF DISEASE

Wrapped to Adapt: Experience-Dependent Myelination

(2017) Christopher W. Mount et al.   NEURON

Major depressive disorder and anxiety disorders from the glial perspective: Etiological mechanisms, intervention and monitoring

(2017) Mari Sild et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

MicroRNA-21: Expression in oligodendrocytes and correlation with low myelin mRNAs in depression and alcoholism

(2017) José Javier Miguel-Hidalgo et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Magnetization Transfer Imaging of Treatment-resistant Depression

(2017) Zhiyun Jia et al.   RADIOLOGY

Loss of Saltation and Presynaptic Action Potential Failure in Demyelinated Axons

(2017) Mustafa S. Hamada et al.   Frontiers in Cellular Neuroscience

White Matter Hyperintensities and Their Association With Suicidally in Major Affective Disorders: A Meta-Analysis of Magnetic Resonance Imaging Studies

(2017) Maria Conceição Grangeon et al.   CNS SPECTRUMS

Myelination of the brain in Major Depressive Disorder: An in vivo quantitative magnetic resonance imaging study

(2017) Matthew D. Sacchet et al.   Scientific Reports

Fluvoxamine stimulates oligodendrogenesis of cultured neural stem cells and attenuates inflammation and demyelination in an animal model of multiple sclerosis

(2017) Majid Ghareghani et al.   Scientific Reports

Electrophysiological properties of NG2 + cells: Matching physiological studies with gene expression profiles

(2016) Valerie A. Larson et al.   BRAIN RESEARCH

Repetitive transcranial magnetic stimulation for treatment resistant depression: Re-establishing connections

(2016) Rodney J. Anderson et al.   CLINICAL NEUROPHYSIOLOGY

Altered intracortical myelin staining in the dorsolateral prefrontal cortex in severe mental illness

(2016) Evelyn M. R. Lake et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Chronic stress regulates NG2 + cell maturation and myelination in the prefrontal cortex through induction of death receptor 6

(2016) Youjun Yang et al.   EXPERIMENTAL NEUROLOGY

Role of trophic factors GDNF, IGF-1 and VEGF in major depressive disorder: A comprehensive review of human studies

(2016) Ajaykumar N. Sharma et al.   JOURNAL OF AFFECTIVE DISORDERS

Microstructural Differences in the Corpus Callosum in Patients With Bipolar Disorder and Major Depressive Disorder

(2016) Kiwamu Matsuoka et al.   JOURNAL OF CLINICAL PSYCHIATRY

Clemastine Enhances Myelination in the Prefrontal Cortex and Rescues Behavioral Changes in Socially Isolated Mice

(2016) J. Liu et al.   JOURNAL OF NEUROSCIENCE

Rapid production of new oligodendrocytes is required in the earliest stages of motor-skill learning

(2016) Lin Xiao et al.   NATURE NEUROSCIENCE

N-acetylaspartate supports the energetic demands of developmental myelination via oligodendroglial aspartoacylase

(2016) Jeremy S. Francis et al.   NEUROBIOLOGY OF DISEASE

Oligodendroglial NMDA Receptors Regulate Glucose Import and Axonal Energy Metabolism

(2016) Aiman S. Saab et al.   NEURON

Diversity Matters: A Revised Guide to Myelination

(2016) Giulio Srubek Tomassy et al.   TRENDS IN CELL BIOLOGY

Association between chronic stress-induced structural abnormalities in Ranvier nodes and reduced oligodendrocyte activity in major depression

(2016) Shingo Miyata et al.   Scientific Reports

Developmental Origin of Oligodendrocyte Lineage Cells Determines Response to Demyelination and Susceptibility to Age-Associated Functional Decline

(2016) Abbe H. Crawford et al.   Cell Reports

A large fraction of neocortical myelin ensheathes axons of local inhibitory neurons

(2016) Kristina D Micheva et al.   eLife

Neuropathology of mood disorders: do we see the stigmata of inflammation?

(2016) N Mechawar et al.   Translational Psychiatry

Mechanisms of sodium channel clustering and its influence on axonal impulse conduction

(2015) Sean A. Freeman et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Role of White Matter Abnormalities in Treatment-Resistant Depression: A Systematic Review

(2015) Gianluca Serafini et al.   CURRENT PHARMACEUTICAL DESIGN

Microstructural abnormalities in anterior callosal fibers and their relationship with cognitive function in major depressive disorder and bipolar disorder: A tract-specific analysis study

(2015) Shinichi Yamada et al.   JOURNAL OF AFFECTIVE DISORDERS

BDNF as a biomarker for successful treatment of mood disorders: A systematic & quantitative meta-analysis

(2015) Maryna Polyakova et al.   JOURNAL OF AFFECTIVE DISORDERS

Myelin Loss and Axonal Ion Channel Adaptations Associated with Gray Matter Neuronal Hyperexcitability

(2015) M. S. Hamada et al.   JOURNAL OF NEUROSCIENCE

Fluoxetine Prevents Oligodendrocyte Cell Death by Inhibiting Microglia Activation after Spinal Cord Injury

(2015) Jee Y. Lee et al.   JOURNAL OF NEUROTRAUMA

Oligodendrocyte morphometry and expression of myelin – Related mRNA in ventral prefrontal white matter in major depressive disorder

(2015) Grazyna Rajkowska et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Genetic and early environmental influences on the serotonin system: consequences for brain development and risk for psychopathology

(2015) Linda Booij et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Genetic and Stress-Induced Loss of NG2 Glia Triggers Emergence of Depressive-like Behaviors through Reduced Secretion of FGF2

(2015) Fikri Birey et al.   NEURON

Axonal myelin increase in the callosal genu in depression but not schizophrenia

(2015) M. R. Williams et al.   PSYCHOLOGICAL MEDICINE

Interneurons and oligodendrocyte progenitors form a structured synaptic network in the developing neocortex

(2015) David Orduz et al.   eLife

Effect of Early Institutionalization and Foster Care on Long-term White Matter Development

(2015) Johanna Bick et al.   JAMA Pediatrics

Social Experience-Dependent Myelination: An Implication for Psychiatric Disorders

(2015) Michihiro Toritsuka et al.   NEURAL PLASTICITY

Myelin Membrane Wrapping of CNS Axons by PI(3,4,5)P3-Dependent Polarized Growth at the Inner Tongue

(2014) Nicolas Snaidero et al.   CELL

Lithium in the Treatment of Major Depressive Disorder

(2014) Tom Bschor   DRUGS

Myelination, oligodendrocytes, and serious mental illness

(2014) V. Haroutunian et al.   GLIA

Early phenotypic asymmetry of sister oligodendrocyte progenitor cells after mitosis and its modulation by aging and extrinsic factors

(2014) Enrica Boda et al.   GLIA

Shortened telomere length in white matter oligodendrocytes in major depression: potential role of oxidative stress

(2014) Attila Szebeni et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Desvenlafaxine prevents white matter injury and improves the decreased phosphorylation of the rate-limiting enzyme of cholesterol synthesis in a chronic mouse model of depression

(2014) Junhui Wang et al.   JOURNAL OF NEUROCHEMISTRY

Alcohol Binge Drinking during Adolescence or Dependence during Adulthood Reduces Prefrontal Myelin in Male Rats

(2014) W. M. Vargas et al.   JOURNAL OF NEUROSCIENCE

The Genetics of Major Depression

(2014) Jonathan Flint et al.   NEURON

Multiple Modes of Communication between Neurons and Oligodendrocyte Precursor Cells

(2014) Paloma P. Maldonado et al.   NEUROSCIENTIST

Increased Precursor Cell Proliferation after Deep Brain Stimulation for Parkinson's Disease: A Human Study

(2014) Vinata Vedam-Mai et al.   PLoS One

Pro-Inflammatory Cytokines Reduce the Proliferation of NG2 Cells and Increase Shedding of NG2 In Vivo and In Vitro

(2014) Malin Wennström et al.   PLoS One

The Effects of Environmental Enrichment on Depressive and Anxiety-Relevant Behaviors in Socially Isolated Prairie Voles

(2014) Angela J. Grippo et al.   PSYCHOSOMATIC MEDICINE

Distinct Profiles of Myelin Distribution Along Single Axons of Pyramidal Neurons in the Neocortex

(2014) G. S. Tomassy et al.   SCIENCE

Oligodendrocyte Precursor Cells Modulate the Neuronal Network by Activity-Dependent Ectodomain Cleavage of Glial NG2

(2014) Dominik Sakry et al.   PLOS BIOLOGY

Beyond cell replacement: unresolved roles of NG2-expressing progenitors

(2014) Enrica Boda et al.   Frontiers in Neuroscience

White matter integrity alterations in young healthy adults reporting childhood trauma: A diffusion tensor imaging study

(2013) Shaojia Lu et al.   AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY

Ketamine and imipramine in the nucleus accumbens regulate histone deacetylation induced by maternal deprivation and are critical for associated behaviors

(2013) Gislaine Z. Réus et al.   BEHAVIOURAL BRAIN RESEARCH

Abnormalities of cortical-limbic-cerebellar white matter networks may contribute to treatment-resistant depression: a diffusion tensor imaging study

(2013) Hong-jun Peng et al.   BMC Psychiatry

Postnatal Down-Regulation of the GABAA Receptor γ2 Subunit in Neocortical NG2 Cells Accompanies Synaptic-to-Extrasynaptic Switch in the GABAergic Transmission Mode

(2013) Maddalena Balia et al.   CEREBRAL CORTEX

Disease severity is correlated to tract specific changes of fractional anisotropy in MD and CM thalamus—A DTI study in major depressive disorder

(2013) Annemarie Osoba et al.   JOURNAL OF AFFECTIVE DISORDERS

Distribution of Corticosteroid Receptors in Mature Oligodendrocytes and Oligodendrocyte Progenitors of the Adult Mouse Brain

(2013) Yumiko Matsusue et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Myelin Loss Does Not Lead to Axonal Degeneration in a Long-Lived Model of Chronic Demyelination

(2013) C. M. Smith et al.   JOURNAL OF NEUROSCIENCE

The Brain on Stress: Vulnerability and Plasticity of the Prefrontal Cortex over the Life Course

(2013) Bruce S. McEwen et al.   NEURON

Oxidative Stress and Proinflammatory Cytokines Contribute to Demyelination and Axonal Damage in a Cerebellar Culture Model of Neuroinflammation

(2013) Alessandra di Penta et al.   PLoS One

Early-Stage Psychotherapy Produces Elevated Frontal White Matter Integrity in Adult Major Depressive Disorder

(2013) Tao Wang et al.   PLoS One

The effect of glia-glia interactions on oligodendrocyte precursor cell biology during development and in demyelinating diseases

(2013) Diego Clemente et al.   Frontiers in Cellular Neuroscience

Oligodendroglia and neurotrophic factors in neurodegeneration

(2013) Andrew N. Bankston et al.   Neuroscience Bulletin

Burden of Depressive Disorders by Country, Sex, Age, and Year: Findings from the Global Burden of Disease Study 2010

(2013) Alize J. Ferrari et al.   PLOS MEDICINE

Fibroblast Growth Factor-2: An Endogenous Antidepressant and Anxiolytic Molecule?

(2012) Cortney A. Turner et al.   BIOLOGICAL PSYCHIATRY

Antidepressant Effects of Fibroblast Growth Factor-2 in Behavioral and Cellular Models of Depression

(2012) Maha Elsayed et al.   BIOLOGICAL PSYCHIATRY

Distinguishing between Unipolar Depression and Bipolar Depression: Current and Future Clinical and Neuroimaging Perspectives

(2012) Jorge Renner Cardoso de Almeida et al.   BIOLOGICAL PSYCHIATRY

Frontal white matter biochemical abnormalities in first-episode, treatment-naive patients with major depressive disorder: A proton magnetic resonance spectroscopy study

(2012) Ying Wang et al.   JOURNAL OF AFFECTIVE DISORDERS

Oligodendroglia metabolically support axons and contribute to neurodegeneration

(2012) Youngjin Lee et al.   NATURE

Impaired adult myelination in the prefrontal cortex of socially isolated mice

(2012) Jia Liu et al.   NATURE NEUROSCIENCE

Antidepressant Treatment Normalizes White Matter Volume in Patients with Major Depression

(2012) Ling-Li Zeng et al.   PLoS One

A Critical Period for Social Experience-Dependent Oligodendrocyte Maturation and Myelination

(2012) M. Makinodan et al.   SCIENCE

Enriched environment and physical activity reduce microglia and influence the fate of NG2 cells in the amygdala of adult mice

(2011) Dan Ehninger et al.   CELL AND TISSUE RESEARCH

Correlations between brain-derived neurotrophic factor and clinical symptoms in medicated patients with major depression

(2011) Emi Satomura et al.   JOURNAL OF AFFECTIVE DISORDERS

A novel, rapid, cell-counting method for unfixed frozen brains comprehensively quantifies at least four neural cell populations

(2011) Y Hayashi et al.   MOLECULAR PSYCHIATRY

Plasma Corticosterone Activates SGK1 and Induces Morphological Changes in Oligodendrocytes in Corpus Callosum

(2011) Shingo Miyata et al.   PLoS One

The prefrontal–limbic network in depression: A core pathology of synapse regression

(2011) M.R. Bennett   PROGRESS IN NEUROBIOLOGY

White matter abnormalities in major depression: Evidence from post-mortem, neuroimaging and genetic studies

(2010) Ming Wei Tham et al.   JOURNAL OF AFFECTIVE DISORDERS

Myelination and the trophic support of long axons

(2010) Klaus-Armin Nave   NATURE REVIEWS NEUROSCIENCE

A Molecular Signature of Depression in the Amygdala

(2009) Etienne Sibille et al.   AMERICAN JOURNAL OF PSYCHIATRY

Characterization of QKI Gene Expression, Genetics, and Epigenetics in Suicide Victims with Major Depressive Disorder

(2009) Timothy A. Klempan et al.   BIOLOGICAL PSYCHIATRY

Epidemiologic heterogeneity of common mood and anxiety disorders over the lifecourse in the general population: a systematic review

(2009) Arijit Nandi et al.   BMC Psychiatry

Altered gene expression of histone deacetylases in mood disorder patients

(2009) Teruyuki Hobara et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis

(2009) Andrea Cipriani et al.   LANCET

HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the β-catenin–TCF interaction

(2009) Feng Ye et al.   NATURE NEUROSCIENCE

Subcortical oligodendrocyte- and astrocyte-associated gene expression in subjects with schizophrenia, major depression and bipolar disorder

(2009) Kevin Barley et al.   SCHIZOPHRENIA RESEARCH

Anticonvulsants in the Treatment of Major Depressive Disorder

(2009) Daniel V. Vigo et al.   HARVARD REVIEW OF PSYCHIATRY

Macromolecular White Matter Abnormalities in Geriatric Depression: A Magnetization Transfer Imaging Study

(2008) Faith M. Gunning-Dixon et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

On the development of human corticospinal oscillations: age-related changes in EEGEMG coherence and cumulant

(2008) Leon M. James et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Satellite NG2 Progenitor Cells Share Common Glutamatergic Inputs with Associated Interneurons in the Mouse Dentate Gyrus

(2008) J.-M. Mangin et al.   JOURNAL OF NEUROSCIENCE

Depression in multiple sclerosis: Review and theoretical proposal

(2008) PETER A. ARNETT et al.   JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY

Correlation analysis between genome-wide expression profiles and cytoarchitectural abnormalities in the prefrontal cortex of psychiatric disorders

(2008) S Kim et al.   MOLECULAR PSYCHIATRY

Corticolimbic Transcriptome Changes are State-Dependent and Region-Specific in a Rodent Model of Depression and of Antidepressant Reversal

(2008) Alexandre Surget et al.   NEUROPSYCHOPHARMACOLOGY

Major Depressive Disorder

(2008) R.H. Belmaker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Frontal White Matter Anisotropy and Antidepressant Remission in Late-Life Depression

(2008) Warren D. Taylor et al.   PLoS One

Periventricular white matter hyperintensities as predictors of suicide attempts in bipolar disorders and unipolar depression

(2008) Maurizio Pompili et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY