Oligodendroglia and neurotrophic factors in neurodegeneration

Myelin breakdown mediates age-related slowing in cognitive processing speed in healthy elderly men

(2012) Po H. Lu et al.   BRAIN AND COGNITION

Multimodal MRI Analysis of the Corpus Callosum Reveals White Matter Differences in Presymptomatic and Early Huntington's Disease

(2012) M. Di Paola et al.   CEREBRAL CORTEX

Mitochondrial changes within axons in multiple sclerosis

(2012) Graham R. Campbell et al.   CURRENT OPINION IN NEUROLOGY

Exogenous Leukemia Inhibitory Factor Stimulates Oligodendrocyte Progenitor Cell Proliferation and Enhances Hippocampal Remyelination

(2012) B. E. Deverman et al.   JOURNAL OF NEUROSCIENCE

Loss of Neuron-Astroglial Interaction Rapidly Induces Protective CNTF Expression after Stroke in Mice

(2012) S. S. Kang et al.   JOURNAL OF NEUROSCIENCE

Targeted Ablation of Oligodendrocytes Induces Axonal Pathology Independent of Overt Demyelination

(2012) L.-J. Oluich et al.   JOURNAL OF NEUROSCIENCE

NGF and nitrosative stress in patients with Huntington's disease

(2012) Inmaculada Tasset et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Oligodendroglia metabolically support axons and contribute to neurodegeneration

(2012) Youngjin Lee et al.   NATURE

Progressive multiple sclerosis: pathology and pathogenesis

(2012) Hans Lassmann et al.   Nature Reviews Neurology

Intranasal “painless” Human Nerve Growth Factors Slows Amyloid Neurodegeneration and Prevents Memory Deficits in App X PS1 Mice

(2012) Simona Capsoni et al.   PLoS One

Pelizaeus-Merzbacher Disease, Pelizaeus-Merzbacher-Like Disease 1, and Related Hypomyelinating Disorders

(2012) Grace Hobson et al.   SEMINARS IN NEUROLOGY

Central nervous system rather than immune cell-derived BDNF mediates axonal protective effects early in autoimmune demyelination

(2011) De-Hyung Lee et al.   ACTA NEUROPATHOLOGICA

White matter integrity and vulnerability to Alzheimer's disease: Preliminary findings and future directions

(2011) Brian T. Gold et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Functional role of brain-derived neurotrophic factor in neuroprotective autoimmunity: therapeutic implications in a model of multiple sclerosis

(2011) R. A. Linker et al.   BRAIN

Oxidative damage in multiple sclerosis lesions

(2011) L. Haider et al.   BRAIN

Myelin damage of hippocampus and cerebral cortex in rat pentylenetetrazol model

(2011) Yu You et al.   BRAIN RESEARCH

Schizophrenia as a disorder of disconnectivity

(2011) Andrea Schmitt et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

The QKI-PLP pathway controls SIRT2 abundance in CNS myelin

(2011) H. Zhu et al.   GLIA

An Alzheimer's disease-relevant presenilin-1 mutation augments amyloid-beta-induced oligodendrocyte dysfunction

(2011) Maya K. Desai et al.   GLIA

The role of dorsal root ganglia activation and brain-derived neurotrophic factor in multiple sclerosis

(2011) Wenjun Zhu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Levels of BDNF Impact Oligodendrocyte Lineage Cells following a Cuprizone Lesion

(2011) M. W. VonDran et al.   JOURNAL OF NEUROSCIENCE

Glia: Initiators and progressors of pathology in Parkinson's disease

(2011) Glenda M. Halliday et al.   MOVEMENT DISORDERS

Neuropathology of sporadic Parkinson's disease: Evaluation and changes of concepts

(2011) Kurt A. Jellinger   MOVEMENT DISORDERS

White matter lesions in Parkinson disease

(2011) Nicolaas I. Bohnen et al.   Nature Reviews Neurology

The neuropathology, pathophysiology and genetics of multiple system atrophy

(2011) Z. Ahmed et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Spatial and Temporal Profiles of Growth Factor Expression during CNS Demyelination Reveal the Dynamics of Repair Priming

(2011) Viktoria Gudi et al.   PLoS One

Spatial segregation of BDNF transcripts enables BDNF to differentially shape distinct dendritic compartments

(2011) G. Baj et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early Oligodendrocyte/Myelin Pathology in Alzheimer's Disease Mice Constitutes a Novel Therapeutic Target

(2010) Maya K. Desai et al.   AMERICAN JOURNAL OF PATHOLOGY

Improvement in disability after alemtuzumab treatment of multiple sclerosis is associated with neuroprotective autoimmunity

(2010) Joanne L. Jones et al.   BRAIN

Loss of epidermal growth factor regulation by cobalamin in multiple sclerosis

(2010) Giuseppe Scalabrino et al.   BRAIN RESEARCH

Ex vivo delivery of GDNF maintains motor function and prevents neuronal loss in a transgenic mouse model of Huntington's disease

(2010) Allison D. Ebert et al.   EXPERIMENTAL NEUROLOGY

Slowly Progressive Axonal Degeneration in a Rat Model of Chronic, Nonimmune-Mediated Demyelination

(2010) Alastair Wilkins et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Neurodegeneration in a Transgenic Mouse Model of Multiple System Atrophy Is Associated with Altered Expression of Oligodendroglial-Derived Neurotrophic Factors

(2010) K. Ubhi et al.   JOURNAL OF NEUROSCIENCE

Transplantation of Ciliary Neurotrophic Factor-Expressing Adult Oligodendrocyte Precursor Cells Promotes Remyelination and Functional Recovery after SpinalCord Injury

(2010) Q. Cao et al.   JOURNAL OF NEUROSCIENCE

Targeting Glial Cells to Elucidate the Pathogenesis of Huntington’s Disease

(2010) Han-Yun Hsiao et al.   MOLECULAR NEUROBIOLOGY

Myelination and support of axonal integrity by glia

(2010) Klaus-Armin Nave   NATURE

Role of TPPP/p25 on α-synuclein-mediated oligodendroglial degeneration and the protective effect of SIRT2 inhibition in a cellular model of multiple system atrophy☆

(2010) Takafumi Hasegawa et al.   NEUROCHEMISTRY INTERNATIONAL

Distinct 3'UTRs differentially regulate activity-dependent translation of brain-derived neurotrophic factor (BDNF)

(2010) A. G. Lau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Classification and basic pathology of Alzheimer disease

(2009) Charles Duyckaerts et al.   ACTA NEUROPATHOLOGICA

Mitochondrial changes within axons in multiple sclerosis

(2009) D. J. Mahad et al.   BRAIN

The relation between inflammation and neurodegeneration in multiple sclerosis brains

(2009) Josa M. Frischer et al.   BRAIN

α-Synuclein Aggregation and Ser-129 Phosphorylation-dependent Cell Death in Oligodendroglial Cells

(2009) Christine L. Kragh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

α-Synuclein Promotes the Recruitment of Tau to Protein Inclusions in Oligodendroglial Cells: Effects of Oxidative and Proteolytic Stress

(2009) Michael Riedel et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

New Insights in the Biology of BDNF Synthesis and Release: Implications in CNS Function

(2009) M. E. Greenberg et al.   JOURNAL OF NEUROSCIENCE

Leukemia inhibitory factor regulates the timing of oligodendrocyte development and myelination in the postnatal optic nerve

(2009) Tomoko Ishibashi et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Proteome and transcriptome analysis suggests oligodendrocyte dysfunction in schizophrenia

(2009) Daniel Martins-de-Souza   JOURNAL OF PSYCHIATRIC RESEARCH

Brain-derived neurotrophic factor and TrkB receptor in experimental autoimmune encephalomyelitis and multiple sclerosis

(2009) Lorenzo De Santi et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Virtual hypoxia and chronic necrosis of demyelinated axons in multiple sclerosis

(2009) Bruce D Trapp et al.   LANCET NEUROLOGY

Multiple system atrophy: an update

(2009) Nadia Stefanova et al.   LANCET NEUROLOGY

Brain-derived neurotrophic factor in neurodegenerative diseases

(2009) Chiara Zuccato et al.   Nature Reviews Neurology

Functional recovery of callosal axons following demyelination: a critical window

(2009) D.K. Crawford et al.   NEUROSCIENCE

Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms

(2009) Jennifer Bradford et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epidermal Growth Factor Induces the Progeny of Subventricular Zone Type B Cells to Migrate and Differentiate into Oligodendrocytes

(2009) Oscar Gonzalez-Perez et al.   STEM CELLS

Multiple system atrophy: A primary oligodendrogliopathy

(2008) Gregor K. Wenning et al.   ANNALS OF NEUROLOGY

Axon-Glial Signaling and the Glial Support of Axon Function

(2008) Klaus-Armin Nave et al.   Annual Review of Neuroscience

Mitochondrial defects in acute multiple sclerosis lesions

(2008) Don Mahad et al.   BRAIN

Prevention of axonal injury using calpain inhibitor in chronic progressive experimental autoimmune encephalomyelitis

(2008) Getaw Worku Hassen et al.   BRAIN RESEARCH

Leukemia inhibitory factor signaling modulates both central nervous system demyelination and myelin repair

(2008) Mark P. Marriott et al.   GLIA

Triple-transgenic Alzheimer's disease mice exhibit region-specific abnormalities in brain myelination patterns prior to appearance of amyloid and tau pathology

(2008) Maya K. Desai et al.   GLIA

Oligodendrogenesis of adult neural progenitors: differential effects of ciliary neurotrophic factor and mesenchymal stem cell derived factors

(2008) Francisco J. Rivera et al.   JOURNAL OF NEUROCHEMISTRY

Remyelination in the CNS: from biology to therapy

(2008) Robin J. M. Franklin et al.   NATURE REVIEWS NEUROSCIENCE

NGF and BDNF signaling control amyloidogenic route and A  production in hippocampal neurons

(2008) C. Matrone et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human neural progenitor cells over-expressing IGF-1 protect dopamine neurons and restore function in a rat model of Parkinson's disease

(2007) Allison D. Ebert et al.   EXPERIMENTAL NEUROLOGY

BDNF mRNA splice variants display activity-dependent targeting to distinct hippocampal laminae

(2007) C. Chiaruttini et al.   MOLECULAR AND CELLULAR NEUROSCIENCE