Autophagy stimulation and intracellular sodium reduction as mediators of the cardioprotective effect of sodium–glucose cotransporter 2 inhibitors

Delayed ischemic contracture onset by Empagliflozin associates with NHE-1 inhibition and is dependent on insulin in isolated mouse hearts

(2019) Laween Uthman et al.   CARDIOVASCULAR RESEARCH

Biological Functions of Autophagy Genes: A Disease Perspective

(2019) Beth Levine et al.   CELL

Silencing of the Na+/H+ exchanger 1(NHE-1) prevents cardiac structural and functional remodeling induced by angiotensin II

(2019) Andrés J. Medina et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

The effects of empagliflozin treatment on cardiac function and structure in patients with type 2 diabetes - a cardiac MR study

(2019) Neale D. Cohen et al.   INTERNAL MEDICINE JOURNAL

Cardiovascular Effects of Treatment with the Ketone Body 3-Hydroxybutyrate in Chronic Heart Failure Patients

(2019) Roni Nielsen et al.   CIRCULATION

Effects of Canagliflozin on Heart Failure Outcomes Associated with Preserved and Reduced Ejection Fraction in Type 2 Diabetes: Results from the CANVAS Program

(2019) Gemma A. Figtree et al.   CIRCULATION

Effect of Dapagliflozin on Heart Failure and Mortality in Type 2 Diabetes Mellitus

(2019) Eri T. Kato et al.   CIRCULATION

SGLT2 inhibition with empagliflozin improves coronary microvascular function and cardiac contractility in prediabetic ob/ob−/− mice

(2019) Damilola D. Adingupu et al.   Cardiovascular Diabetology

Inhibition of sodium–glucose cotransporter-2 preserves cardiac function during regional myocardial ischemia independent of alterations in myocardial substrate utilization

(2019) Hana E. Baker et al.   BASIC RESEARCH IN CARDIOLOGY

The sodium–glucose co-transporter 2 inhibitor empagliflozin attenuates cardiac fibrosis and improves ventricular hemodynamics in hypertensive heart failure rats

(2019) Hsiang-Chun Lee et al.   Cardiovascular Diabetology

Metformin Enhances Autophagy and Provides Cardioprotection in δ-Sarcoglycan Deficiency-Induced Dilated Cardiomyopathy

(2019) Hiromitsu Kanamori et al.   Circulation-Heart Failure

Sodium–glucose co‐transporter 2 inhibition with empagliflozin improves cardiac function in non‐diabetic rats with left ventricular dysfunction after myocardial infarction

(2019) Salva R. Yurista et al.   EUROPEAN JOURNAL OF HEART FAILURE

Empagliflozin Ameliorates Adverse Left Ventricular Remodeling in Nondiabetic Heart Failure by Enhancing Myocardial Energetics

(2019) Carlos G. Santos-Gallego et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Acute canagliflozin treatment protects against in vivo myocardial ischemia–reperfusion injury in non-diabetic male rats and enhances endothelium-dependent vasorelaxation

(2019) Alex Ali Sayour et al.   Journal of Translational Medicine

Metformin promotes autophagy in ischemia/reperfusion myocardium via cytoplasmic AMPKα1 and nuclear AMPKα2 pathways

(2019) Yishi Wang et al.   LIFE SCIENCES

Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy

(2019) Vlado Perkovic et al.   NEW ENGLAND JOURNAL OF MEDICINE

Possible involvement of normalized Pin1 expression level and AMPK activation in the molecular mechanisms underlying renal protective effects of SGLT2 inhibitors in mice

(2019) Masa-Ki Inoue et al.   Diabetology & Metabolic Syndrome

Effect of Empagliflozin on Left Ventricular Mass in Patients with Type 2 Diabetes and Coronary Artery Disease: The EMPA-HEART CardioLink-6 Randomized Clinical Trial

(2019) Subodh Verma et al.   CIRCULATION

Dapagliflozin Effects on Biomarkers, Symptoms, and Functional Status in Patients With Heart Failure With Reduced Ejection Fraction: The DEFINE-HF Trial

(2019) Michael E. Nassif et al.   CIRCULATION

Effects of the sodium‐glucose co‐transporter‐2 inhibitor dapagliflozin on estimated plasma volume in patients with type 2 diabetes

(2019) Claire C. J. Dekkers et al.   DIABETES OBESITY & METABOLISM

What causes sudden death in patients with chronic heart failure and a reduced ejection fraction?

(2019) Milton Packer   EUROPEAN HEART JOURNAL

Effects of empagliflozin on nondiabetic salt-sensitive hypertension in uninephrectomized rats

(2019) Sua Kim et al.   HYPERTENSION RESEARCH

Effect of ipragliflozin, an SGLT2 inhibitor, on cardiac histopathological changes in a non-diabetic rat model of cardiomyopathy

(2019) Toshiyuki Takasu et al.   LIFE SCIENCES

Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction

(2019) John J.V. McMurray et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nephropathy in diabetic db/db mice is accelerated by high protein diet and improved by the SGLT2 inhibitor dapagliflozin

(2019) Sisse Andersen Nørgaard et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Metformin Use Is Associated With a Lower Risk of Hospitalization for Heart Failure in Patients With Type 2 Diabetes Mellitus: a Retrospective Cohort Analysis

(2019) Chin‐Hsiao Tseng   Journal of the American Heart Association

Mediators of the Effects of Canagliflozin on Heart Failure in Patients With Type 2 Diabetes

(2019) JingWei Li et al.   JACC-Heart Failure

Empagliflozin reduces the levels of CD36 and cardiotoxic lipids while improving autophagy in the hearts of Zucker diabetic fatty rats

(2019) Alana Aragón-Herrera et al.   BIOCHEMICAL PHARMACOLOGY

Metformin alleviates oxidative stress and enhances autophagy in diabetic kidney disease via AMPK/SIRT1-FoxO1 pathway

(2019) Huiwen Ren et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Patterns of glucose-lowering medication use in patients with type 2 diabetes and heart failure. Insights from the Diabetes Collaborative Registry (DCR)

(2018) Suzanne V. Arnold et al.   AMERICAN HEART JOURNAL

Autophagy balances inflammation in innate immunity

(2018) Vojo Deretic et al.   Autophagy

Canagliflozin exerts anti-inflammatory effects by inhibiting intracellular glucose metabolism and promoting autophagy in immune cells

(2018) Chenke Xu et al.   BIOCHEMICAL PHARMACOLOGY

SIRT1 and HIF1α signaling in metabolism and immune responses

(2018) Qing Yu et al.   CANCER LETTERS

SGLT-2-inhibition with dapagliflozin reduces tissue sodium content: a randomised controlled trial

(2018) M. V. Karg et al.   Cardiovascular Diabetology

Sirtuin 1 activation attenuates cardiac fibrosis in a rodent pressure overload model by modifying Smad2/3 transactivation

(2018) Antoinette Bugyei-Twum et al.   CARDIOVASCULAR RESEARCH

Cardiomyocyte-specific deletion of Sirt1 gene sensitizes myocardium to ischaemia and reperfusion injury

(2018) Lin Wang et al.   CARDIOVASCULAR RESEARCH

Canagliflozin and Heart Failure in Type 2 Diabetes Mellitus: Results From the CANVAS Program (Canagliflozin Cardiovascular Assessment Study)

(2018) Karin Rådholm et al.   CIRCULATION

Sodium–glucose cotransporter 2 inhibition normalizes glucose metabolism and suppresses oxidative stress in the kidneys of diabetic mice

(2018) Shinji Tanaka et al.   KIDNEY INTERNATIONAL

The Cardioprotective Effect of Metformin in Doxorubicin-Induced Cardiotoxicity: The Role of Autophagy

(2018) Rita Zilinyi et al.   MOLECULES

High Basolateral Glucose Increases Sodium-Glucose Cotransporter 2 and Reduces Sirtuin-1 in Renal Tubules through Glucose Transporter-2 Detection

(2018) Hiroyuki Umino et al.   Scientific Reports

Canagliflozin inhibits interleukin-1β-stimulated cytokine and chemokine secretion in vascular endothelial cells by AMP-activated protein kinase-dependent and -independent mechanisms

(2018) Sarah J. Mancini et al.   Scientific Reports

Cardiovascular outcomes with glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes: a meta-analysis

(2018) M Angelyn Bethel et al.   Lancet Diabetes & Endocrinology

Empagliflozin rescues diabetic myocardial microvascular injury via AMPK-mediated inhibition of mitochondrial fission

(2018) Hao Zhou et al.   Redox Biology

Regulation of diabetic cardiomyopathy by caloric restriction is mediated by intracellular signaling pathways involving ‘SIRT1 and PGC-1α’

(2018) Maayan Waldman et al.   Cardiovascular Diabetology

Empagliflozin lowers myocardial ketone utilization while preserving glucose utilization in diabetic hypertensive heart disease: A hyperpolarized 13 C magnetic resonance spectroscopy study

(2018) Desiree Abdurrachim et al.   DIABETES OBESITY & METABOLISM

Impact of dapagliflozin on left ventricular diastolic function of patients with type 2 diabetic mellitus with chronic heart failure

(2018) Fumitaka Soga et al.   Cardiovascular Diabetology

Dapagliflozin Attenuates Na+/H+ Exchanger-1 in Cardiofibroblasts via AMPK Activation

(2018) Yumei Ye et al.   CARDIOVASCULAR DRUGS AND THERAPY

Increased Cardiac Uptake of Ketone Bodies and Free Fatty Acids in Human Heart Failure and Hypertrophic Left Ventricular Remodeling

(2018) Gabor Voros et al.   Circulation-Heart Failure

SGLT2 inhibitors for primary and secondary prevention of cardiovascular and renal outcomes in type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials

(2018) Thomas A Zelniker et al.   LANCET

Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes

(2018) Stephen D. Wiviott et al.   NEW ENGLAND JOURNAL OF MEDICINE

Direct Cardiac Actions of Sodium Glucose Cotransporter 2 Inhibitors Target Pathogenic Mechanisms Underlying Heart Failure in Diabetic Patients

(2018) Laween Uthman et al.   Frontiers in Physiology

Chronic O-GlcNAcylation and Diabetic Cardiomyopathy: The Bitterness of Glucose

(2018) Simon Ducheix et al.   Frontiers in Endocrinology

Sodium-dependent glucose transporters (SGLT) in human ischemic heart: A new potential pharmacological target

(2017) Alessandra Di Franco et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes

(2017) Bruce Neal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Comparative Safety of Sulfonylurea and Metformin Monotherapy on the Risk of Heart Failure: A Cohort Study

(2017) Christianne L. Roumie et al.   Journal of the American Heart Association

Effects of Sodium-Glucose Cotransporter 2 Inhibitors for the Treatment of Patients With Heart Failure

(2017) Milton Packer et al.   JAMA Cardiology

AMPKα2 Protects Against the Development of Heart Failure by Enhancing Mitophagy via PINK1 Phosphorylation

(2017) Bei Wang et al.   CIRCULATION RESEARCH

Sodium-myoinositol cotransporter-1, SMIT1, mediates the production of reactive oxygen species induced by hyperglycemia in the heart

(2017) Anne Van Steenbergen et al.   Scientific Reports

The role of metformin and resveratrol in the prevention of hypoxia-inducible factor 1α accumulation and fibrosis in hypoxic adipose tissue

(2016) Xiaole Li et al.   BRITISH JOURNAL OF PHARMACOLOGY

Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload–Induced Mitochondrial Dysfunction and Heart FailureCLINICAL PERSPECTIVE

(2016) Akihiro Shirakabe et al.   CIRCULATION

The Failing Heart Relies on Ketone Bodies as a Fuel

(2016) Gregory Aubert et al.   CIRCULATION

Shift to Fatty Substrate Utilization in Response to Sodium–Glucose Cotransporter 2 Inhibition in Subjects Without Diabetes and Patients With Type 2 Diabetes

(2016) Ele Ferrannini et al.   DIABETES

The Na+/Glucose Cotransporter Inhibitor Canagliflozin Activates AMPK by Inhibiting Mitochondrial Function and Increasing Cellular AMP Levels

(2016) Simon A. Hawley et al.   DIABETES

Can a Shift in Fuel Energetics Explain the Beneficial Cardiorenal Outcomes in the EMPA-REG OUTCOME Study? A Unifying Hypothesis

(2016) Sunder Mudaliar et al.   DIABETES CARE

CV Protection in the EMPA-REG OUTCOME Trial: A “Thrifty Substrate” Hypothesis

(2016) Ele Ferrannini et al.   DIABETES CARE

Empagliflozin decreases myocardial cytoplasmic Na+ through inhibition of the cardiac Na+/H+ exchanger in rats and rabbits

(2016) Antonius Baartscheer et al.   DIABETOLOGIA

Heart failure outcomes with empagliflozin in patients with type 2 diabetes at high cardiovascular risk: results of the EMPA-REG OUTCOME®trial

(2016) David Fitchett et al.   EUROPEAN HEART JOURNAL

Hypoxia upregulates Malat1 expression through a CaMKK/AMPK/HIF-1α axis

(2016) Sandrine Sallé-Lefort et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Hypoxia induces autophagy in cardiomyocytes via a hypoxia-inducible factor 1-dependent mechanism

(2016) LAN GUI et al.   Experimental and Therapeutic Medicine

β-Hydroxybutyrate suppresses inflammasome formation by ameliorating endoplasmic reticulum stress via AMPK activation

(2016) Ha Ram Bae et al.   Oncotarget

Dipeptidyl peptidase-4 inhibitors and risk of heart failure in type 2 diabetes: systematic review and meta-analysis of randomised and observational studies

(2016) Ling Li et al.   BMJ-British Medical Journal

Dipeptidyl peptidase-4 inhibitors and risk of heart failure in type 2 diabetes: systematic review and meta-analysis of randomised and observational studies

(2016) Ling Li et al.   BMJ-British Medical Journal

Dapagliflozin, SGLT2 Inhibitor, Attenuates Renal Ischemia-Reperfusion Injury

(2016) Yoon-Kyung Chang et al.   PLoS One

EPAS1/HIF-2α is a driver of mammalian pexophagy

(2015) Miriam J Schönenberger et al.   Autophagy

Signaling pathways and mechanisms of hypoxia-induced autophagy in the animal cells

(2015) Yungyun Fang et al.   CELL BIOLOGY INTERNATIONAL

Loop diuretics, renal function and clinical outcome in patients with heart failure and reduced ejection fraction

(2015) Kevin Damman et al.   EUROPEAN JOURNAL OF HEART FAILURE

Development of autophagy inducers in clinical medicine

(2015) Beth Levine et al.   JOURNAL OF CLINICAL INVESTIGATION

The role of autophagic degradation in the heart

(2015) Kazuhiko Nishida et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

AMPK-Dependent Phosphorylation of GAPDH Triggers Sirt1 Activation and Is Necessary for Autophagy upon Glucose Starvation

(2015) Chunmei Chang et al.   MOLECULAR CELL

The Ketone Body, β-Hydroxybutyrate Stimulates the Autophagic Flux and Prevents Neuronal Death Induced by Glucose Deprivation in Cortical Cultured Neurons

(2015) Lucy Camberos-Luna et al.   NEUROCHEMICAL RESEARCH

Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes

(2015) Bernard Zinman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Reduced SIRT1 expression correlates with enhanced oxidative stress in compensated and decompensated heart failure

(2015) Feridun Akkafa et al.   Redox Biology

Molecular mechanisms and physiological significance of autophagy during myocardial ischemia and reperfusion

(2014) Yutaka Matsui et al.   Autophagy

Metformin alleviates hepatosteatosis by restoring SIRT1-mediated autophagy induction via an AMP-activated protein kinase-independent pathway

(2014) Young Mi Song et al.   Autophagy

A High-Fat Diet and NAD + Activate Sirt1 to Rescue Premature Aging in Cockayne Syndrome

(2014) Morten Scheibye-Knudsen et al.   Cell Metabolism

Regulation of Akt Signaling by Sirtuins

(2014) Vinodkumar B. Pillai et al.   CIRCULATION RESEARCH

Effect of the sodium glucose co-transporter 2 inhibitor canagliflozin on plasma volume in patients with type 2 diabetes mellitus

(2014) S. Sha et al.   DIABETES OBESITY & METABOLISM

Functional Role of Glucose Metabolism, Osmotic Stress, and Sodium-Glucose Cotransporter Isoform-Mediated Transport on Na+/H+ Exchanger Isoform 3 Activity in the Renal Proximal Tubule

(2014) T. D. Pessoa et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

An acetate switch regulates stress erythropoiesis

(2014) Min Xu et al.   NATURE MEDICINE

Adenosine-Mono-Phosphate-Activated Protein Kinase-Independent Effects of Metformin in T Cells

(2014) Marouan Zarrouk et al.   PLoS One

Myocardial energetics in heart failure

(2013) Alexander Nickel et al.   BASIC RESEARCH IN CARDIOLOGY

Renal Hemodynamic Effect of Sodium-Glucose Cotransporter 2 Inhibition in Patients With Type 1 Diabetes Mellitus

(2013) David Z.I. Cherney et al.   CIRCULATION

Hypoxia-inducible Factor-1α (HIF-1α) Protein Diminishes Sodium Glucose Transport 1 (SGLT1) and SGLT2 Protein Expression in Renal Epithelial Tubular Cells (LLC-PK1) under Hypoxia

(2013) Juan R. Zapata-Morales et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of NHE1 activity leads to reduced oxidative stress in heart and mitigates high-fat diet-induced myocardial stress

(2013) Vikram Prasad et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Intracellular Na+ and cardiac metabolism

(2013) Johannes Bay et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Treatment of Anemia with Darbepoetin Alfa in Systolic Heart Failure

(2013) Karl Swedberg et al.   NEW ENGLAND JOURNAL OF MEDICINE

Autophagy in Human Health and Disease

(2013) Augustine M.K. Choi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Deciphering the mechanisms of the Na+/H+ exchanger-3 regulation in organ dysfunction

(2012) Adriana C. C. Girardi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Impaired myocardial autophagy linked to energy metabolism disorders

(2012) Zi-Lun Li et al.   Autophagy

Long-Term Safety, Tolerability, and Weight Loss Associated With Metformin in the Diabetes Prevention Program Outcomes Study

(2012)   DIABETES CARE

The Acetylase/Deacetylase Couple CREB-binding Protein/Sirtuin 1 Controls Hypoxia-inducible Factor 2 Signaling

(2012) Rui Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Autophagy by Metabolic and Stress Signaling Pathways in the Heart

(2012) Youngil Lee et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Endothelial expression of hypoxia-inducible factor 1 protects the murine heart and aorta from pressure overload by suppression of TGF-  signaling

(2012) H. Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Erythropoietin as a treatment of anemia in heart failure: Systematic review of randomized trials

(2011) Dipak Kotecha et al.   AMERICAN HEART JOURNAL

Increased NHE3 abundance and transport activity in renal proximal tubule of rats with heart failure

(2011) Bruna H. Inoue et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

AMP-activated protein kinase modulates cardiac autophagy in diabetic cardiomyopathy

(2011) Zhonglin Xie et al.   Autophagy

Improvement of Cardiac Functions by Chronic Metformin Treatment Is Associated With Enhanced Cardiac Autophagy in Diabetic OVE26 Mice

(2011) Z. Xie et al.   DIABETES

Obligate Role for Ketone Body Oxidation in Neonatal Metabolic Homeostasis

(2011) David G. Cotter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diuretic dose and long-term outcomes in elderly patients with heart failure after hospitalization

(2010) Husam M. Abdel-Qadir et al.   AMERICAN HEART JOURNAL

Elevated Cytosolic Na + Increases Mitochondrial Formation of Reactive Oxygen Species in Failing Cardiac Myocytes

(2010) Michael Kohlhaas et al.   CIRCULATION

Glucose-Induced Regulation of NHEs Activity and SGLTs Expression Involves the PKA Signaling Pathway

(2010) Olívia Beloto-Silva et al.   JOURNAL OF MEMBRANE BIOLOGY

Eplerenone in Patients with Systolic Heart Failure and Mild Symptoms

(2010) Faiez Zannad et al.   NEW ENGLAND JOURNAL OF MEDICINE

Is Autophagy in Response to Ischemia and Reperfusion Protective or Detrimental for the Heart?

(2010) Sebastiano Sciarretta et al.   PEDIATRIC CARDIOLOGY

Hypoxia induces B-type natriuretic peptide release in cell lines derived from human cardiomyocytes

(2009) Gregori Casals et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Metformin Prevents Progression of Heart Failure in Dogs

(2009) Hideyuki Sasaki et al.   CIRCULATION

Impaired Ca2+-handling in HIF-1α+/− mice as a consequence of pressure overload

(2009) Monique Silter et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Regulation of Hypoxia-Inducible Factor 2  Signaling by the Stress-Responsive Deacetylase Sirtuin 1

(2009) E. M. Dioum et al.   SCIENCE

Sodium-Hydrogen Exchange Inhibition by Cariporide to Reduce the Risk of Ischemic Cardiac Events in Patients Undergoing Coronary Artery Bypass Grafting: Results of the EXPEDITION Study

(2008) Robert M. Mentzer et al.   ANNALS OF THORACIC SURGERY

Chronic inhibition of the Na+/H+- exchanger causes regression of hypertrophy, heart failure, and ionic and electrophysiological remodelling

(2008) A Baartscheer et al.   BRITISH JOURNAL OF PHARMACOLOGY

Protein Kinase B/Akt Phosphorylates and Inhibits the Cardiac Na +/ H + Exchanger NHE1

(2008) Andrew K. Snabaitis et al.   CIRCULATION RESEARCH

Activation of Na + /H + Exchanger 1 Is Sufficient to Generate Ca 2+ Signals That Induce Cardiac Hypertrophy and Heart Failure

(2008) Tomoe Y. Nakamura et al.   CIRCULATION RESEARCH

Activation of AMP-Activated Protein Kinase by Metformin Improves Left Ventricular Function and Survival in Heart Failure

(2008) Susheel Gundewar et al.   CIRCULATION RESEARCH

AMP Activated Protein Kinase-α2 Deficiency Exacerbates Pressure-Overload–Induced Left Ventricular Hypertrophy and Dysfunction in Mice

(2008) Ping Zhang et al.   HYPERTENSION

Neuroprotection in Diet-Induced Ketotic Rat Brain after Focal Ischemia

(2008) Michelle A Puchowicz et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM