Dapagliflozin, SGLT2 Inhibitor, Attenuates Renal Ischemia-Reperfusion Injury

The NADPH oxidase inhibitor DPI can abolish hypoxia-induced apoptosis of human kidney proximal tubular epithelial cells through Bcl2 up-regulation via ERK activation without ROS reduction

(2015) Hyunkeun Song et al.   LIFE SCIENCES

Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes

(2015) Bernard Zinman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Insulin stimulates SGLT2-mediated tubular glucose absorption via oxidative stress generation

(2015) Nobutaka Nakamura et al.   Diabetology & Metabolic Syndrome

Biomarkers of calcineurin inhibitor nephrotoxicity in transplantation

(2014) Mangalee Fernando et al.   Biomarkers in Medicine

Hypoxia-inducible Factor-1α (HIF-1α) Protein Diminishes Sodium Glucose Transport 1 (SGLT1) and SGLT2 Protein Expression in Renal Epithelial Tubular Cells (LLC-PK1) under Hypoxia

(2013) Juan R. Zapata-Morales et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of SGLT2 Inhibition in Human Kidney Proximal Tubular Cells—Renoprotection in Diabetic Nephropathy?

(2013) Usha Panchapakesan et al.   PLoS One

Selective Stabilization of HIF-1α in Renal Tubular Cells by 2-Oxoglutarate Analogues

(2012) Gunnar Schley et al.   AMERICAN JOURNAL OF PATHOLOGY

Ischemic pre- and postconditioning has pronounced effects on gene expression profiles in the rat liver after ischemia/reperfusion

(2012) Anders Riegels Knudsen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Hypoxia Inducible Factor 1-Alpha (HIF-1 Alpha) Is Induced during Reperfusion after Renal Ischemia and Is Critical for Proximal Tubule Cell Survival

(2012) Elisa Conde et al.   PLoS One

Disruption of Hypoxia-Inducible Transcription Factor-Prolyl Hydroxylase Domain-1 (PHD-1−/−) Attenuates Ex Vivo Myocardial Ischemia/Reperfusion Injury Through Hypoxia-Inducible Factor-1α Transcription Factor and Its Target Genes in Mice

(2010) Ram Sudheer Adluri et al.   ANTIOXIDANTS & REDOX SIGNALING

HIF in Kidney Disease and Development

(2009) L. Gunaratnam et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Erythropoietin Attenuates Renal Injury in an Experimental Model of Rat Unilateral Ureteral Obstruction via Anti-Inflammatory and Anti-Apoptotic Effects

(2009) Yoon-Kyung Chang et al.   JOURNAL OF UROLOGY

Hypoxic preconditioning reinforces HIF-alpha-dependent HSP70 signaling to reduce ischemic renal failure-induced renal tubular apoptosis and autophagy

(2009) Chung-Hsin Yeh et al.   LIFE SCIENCES

Acute renal failure due to ureteral obstruction in a kidney transplant recipient withCandida albicanscontamination of preservation fluid

(2009) M. Veroux et al.   Transplant Infectious Disease

Repetitive Hypoxic Preconditioning Attenuates Renal Ischemia/Reperfusion Induced Oxidative Injury via Upregulating HIF-1α–Dependent bcl-2 Signaling

(2009) Chih-Ching Yang et al.   TRANSPLANTATION

Inhibition of Hypoxia Inducible Factor Hydroxylases Protects Against Renal Ischemia-Reperfusion Injury

(2008) P. Hill et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

HIF Activation Protects From Acute Kidney Injury

(2008) A. Weidemann et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Hypoxia and Hypoxia-Inducible Factor in Renal Disease

(2008) Masaomi Nangaku et al.   NEPHRON EXPERIMENTAL NEPHROLOGY

Sildenafil attenuates renal injury in an experimental model of rat cisplatin-induced nephrotoxicity

(2008) Kang Wook Lee et al.   TOXICOLOGY

Liver HIF-1 Alpha Induction Precedes Apoptosis Following Normothermic Ischemia-Reperfusion in Rats

(2008) R. Cursio et al.   TRANSPLANTATION PROCEEDINGS