The histone demethylase KDM5 controls developmental timing in Drosophila by promoting prothoracic gland endocycles

Histone H3 lysine K4 methylation and its role in learning and memory

(2019) Bridget E. Collins et al.   Epigenetics & Chromatin

Biology and targeting of the Jumonji-domain histone demethylase family in childhood neoplasia: a preclinical overview

(2019) Tyler S. McCann et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Drosophila Histone Demethylase KDM5 Regulates Social Behavior through Immune Control and Gut Microbiota Maintenance

(2019) Kun Chen et al.   Cell Host & Microbe

MeCP2 in central nervous system glial cells: current updates

(2018) Kedarlal Sharma et al.   ACTA NEUROBIOLOGIAE EXPERIMENTALIS

Prothoracicotropic hormone modulates environmental adaptive plasticity through the control of developmental timing

(2018) MaryJane Shimell et al.   DEVELOPMENT

The Histone Demethylase KDM5 Is Essential for Larval Growth inDrosophila

(2018) Coralie Drelon et al.   GENETICS

A Drosophila Model of Intellectual Disability Caused by Mutations in the Histone Demethylase KDM5

(2018) Sumaira Zamurrad et al.   Cell Reports

The Histone Demethylase KDM5 Is Essential for Larval Growth inDrosophila

(2018) Coralie Drelon et al.   GENETICS

Altered Gene-Regulatory Function of KDM5C by a Novel Mutation Associated With Autism and Intellectual Disability

(2018) Christina N. Vallianatos et al.   Frontiers in Molecular Neuroscience

KDM5 demethylases and their role in cancer cell chemoresistance

(2018) J. Plch et al.   INTERNATIONAL JOURNAL OF CANCER

HER2-positive breast-cancer cell lines are sensitive to KDM5 inhibition: definition of a gene-expression model for the selection of sensitive cases

(2018) Gabriela Paroni et al.   ONCOGENE

Quantifying the contribution of recessive coding variation to developmental disorders

(2018) Hilary C. Martin et al.   SCIENCE

KDM5B is a master regulator of the H3K4-methylome in stem cells, development and cancer

(2018) Besa Xhabija et al.   SEMINARS IN CANCER BIOLOGY

Histone Lysine Methylation and Neurodevelopmental Disorders

(2017) Jeong-Hoon Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

EGFR-dependent TOR-independent endocycles support Drosophila gut epithelial regeneration

(2017) Jinyi Xiang et al.   Nature Communications

Nutrient-Dependent Endocycling in Steroidogenic Tissue Dictates Timing of Metamorphosis in Drosophila melanogaster

(2017) Yuya Ohhara et al.   PLoS Genetics

Steroid hormone induction of temporal gene expression in Drosophila brain neuroblasts generates neuronal and glial diversity

(2017) Mubarak Hussain Syed et al.   eLife

Is H3K4me3 instructive for transcription activation?

(2016) Françoise S. Howe et al.   BIOESSAYS

The H3K4me3/2 histone demethylase RBR-2 controls axon guidance by repressing the actin-remodeling genewsp-1

(2016) Luca Mariani et al.   DEVELOPMENT

A Drosophila Genome-Wide Screen Identifies Regulators of Steroid Hormone Production and Developmental Timing

(2016) E. Thomas Danielsen et al.   DEVELOPMENTAL CELL

The histone demethylase dKDM5/LID interacts with the SIN3 histone deacetylase complex and shares functional similarities with SIN3

(2016) Ambikai Gajan et al.   Epigenetics & Chromatin

Early programming of the oocyte epigenome temporally controls late prophase I transcription and chromatin remodelling

(2016) Paulo Navarro-Costa et al.   Nature Communications

Histone demethylase lysine demethylase 5B in development and cancer

(2016) Mengjiao Han et al.   Oncotarget

A Mouse Model of X-linked Intellectual Disability Associated with Impaired Removal of Histone Methylation

(2016) Shigeki Iwase et al.   Cell Reports

Transcriptome Analysis of Drosophila melanogaster Third Instar Larval Ring Glands Points to Novel Functions and Uncovers a Cytochrome p450 Required for Development

(2016) Danielle Christesen et al.   G3-Genes Genomes Genetics

Kdm5/Lid Regulates Chromosome Architecture in Meiotic Prophase I Independently of Its Histone Demethylase Activity

(2016) Liudmila Zhaunova et al.   PLoS Genetics

Nuclear receptors and Drosophila neuronal remodeling

(2015) Ana Boulanger et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Chromatin deregulation in disease

(2015) Anne C. Mirabella et al.   CHROMOSOMA

Polyploidy

(2015) Laura E. Frawley et al.   CURRENT BIOLOGY

Transcriptional regulation of insect steroid hormone biosynthesis and its role in controlling timing of molting and metamorphosis

(2015) Yuko S. Niwa et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

The Drosophila histone demethylase dKDM5/LID regulates hematopoietic development

(2015) Tomás Morán et al.   DEVELOPMENTAL BIOLOGY

Mutations in the intellectual disability gene KDM5C reduce protein stability and demethylase activity

(2015) Emily Brookes et al.   HUMAN MOLECULAR GENETICS

When bigger is better: the role of polyploidy in organogenesis

(2015) Terry L. Orr-Weaver   TRENDS IN GENETICS

Disrupted intricacy of histone H3K4 methylation in neurodevelopmental disorders

(2015) Christina N Vallianatos et al.   Epigenomics

The Histone Demethylase KDM5 Activates Gene Expression by Recognizing Chromatin Context through Its PHD Reader Motif

(2015) Xingyin Liu et al.   Cell Reports

Epigenetic regulator Lid maintains germline stem cells through regulating JAK-STAT signaling pathway activity

(2015) L. Tarayrah et al.   Biology Open

Enzymes for ecdysteroid biosynthesis: their biological functions in insects and beyond

(2014) Ryusuke Niwa et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

JARID1B Is a Luminal Lineage-Driving Oncogene in Breast Cancer

(2014) Shoji Yamamoto et al.   CANCER CELL

H3K4me3 Breadth Is Linked to Cell Identity and Transcriptional Consistency

(2014) Bérénice A. Benayoun et al.   CELL

Physical and Functional Interactions between the Histone H3K4 Demethylase KDM5A and the Nucleosome Remodeling and Deacetylase (NuRD) Complex

(2014) Gohei Nishibuchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone Demethylase RBP2 Is Critical for Breast Cancer Progression and Metastasis

(2014) Jian Cao et al.   Cell Reports

KDM5 Interacts with Foxo to Modulate Cellular Levels of Oxidative Stress

(2014) Xingyin Liu et al.   PLoS Genetics

Overcoming Intrinsic Multidrug Resistance in Melanoma by Blocking the Mitochondrial Respiratory Chain of Slow-Cycling JARID1Bhigh Cells

(2013) Alexander Roesch et al.   CANCER CELL

Common Origin of Insect Trachea and Endocrine Organs from a Segmentally Repeated Precursor

(2013) Carlos Sánchez-Higueras et al.   CURRENT BIOLOGY

The Histone Demethylase Jarid1b Ensures Faithful Mouse Development by Protecting Developmental Genes from Aberrant H3K4me3

(2013) Mareike Albert et al.   PLoS Genetics

Ecdysone Control of Developmental Transitions: Lessons from Drosophila Research

(2012) Naoki Yamanaka et al.   Annual Review of Entomology

Endoreplication and polyploidy: insights into development and disease

(2012) D. T. Fox et al.   DEVELOPMENT

Polyploidization of glia in neural development links tissue growth to blood-brain barrier integrity

(2012) Y. Unhavaithaya et al.   GENES & DEVELOPMENT

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

dKDM5/LID regulates H3K4me3 dynamics at the transcription-start site (TSS) of actively transcribed developmental genes

(2012) Marta Lloret-Llinares et al.   NUCLEIC ACIDS RESEARCH

The Causes and Consequences of Polyploidy in Normal Development and Cancer

(2011) Teresa Davoli et al.   Annual Review of Cell and Developmental Biology

Regulation of chromatin by histone modifications

(2011) Andrew J Bannister et al.   CELL RESEARCH

Involvement of PI3K/Akt signaling in PTTH-stimulated ecdysteroidogenesis by prothoracic glands of the silkworm, Bombyx mori

(2011) Shi-Hong Gu et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

PLU-1/JARID1B/KDM5B is required for embryonic survival and contributes to cell proliferation in the mammary gland and in ER+ breast cancer cells

(2011) Burchell   INTERNATIONAL JOURNAL OF ONCOLOGY

Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer

(2011) Lauren P. Blair et al.   Cancers

Essential Functions of the Histone Demethylase Lid

(2010) Ling Li et al.   PLoS Genetics

Histone Chaperones ASF1 and NAP1 Differentially Modulate Removal of Active Histone Marks by LID-RPD3 Complexes during NOTCH Silencing

(2009) Yuri M. Moshkin et al.   MOLECULAR CELL

The Insect Neuropeptide PTTH Activates Receptor Tyrosine Kinase Torso to Initiate Metamorphosis

(2009) K. F. Rewitz et al.   SCIENCE

The H3K4 Demethylase Lid Associates with and Inhibits Histone Deacetylase Rpd3

(2008) N. Lee et al.   MOLECULAR AND CELLULAR BIOLOGY