Histone H3 lysine K4 methylation and its role in learning and memory

Widespread transcriptional pausing and elongation control at enhancers

(2018) Telmo Henriques et al.   GENES & DEVELOPMENT

MLL4 Is Required to Maintain Broad H3K4me3 Peaks and Super-Enhancers at Tumor Suppressor Genes

(2018) Shilpa S. Dhar et al.   MOLECULAR CELL

KDM5 histone demethylases repress immune response via suppression of STING

(2018) Lizhen Wu et al.   PLOS BIOLOGY

Molecular and cellular issues of KMT2A variants involved in Wiedemann-Steiner syndrome

(2017) Nicolas Lebrun et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Histone Lysine Methylation and Neurodevelopmental Disorders

(2017) Jeong-Hoon Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Prevalence and architecture of de novo mutations in developmental disorders

(2017)   NATURE

Identification of H3K4me1-associated proteins at mammalian enhancers

(2017) Andrea Local et al.   NATURE GENETICS

Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder

(2017) Ryan K C Yuen et al.   NATURE NEUROSCIENCE

Dynamic association of epigenetic H3K4me3 and DNA 5hmC marks in the dorsal hippocampus and anterior cingulate cortex following reactivation of a fear memory

(2017) William M. Webb et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

KMT2A and KMT2B Mediate Memory Function by Affecting Distinct Genomic Regions

(2017) Cemil Kerimoglu et al.   Cell Reports

Loss of Kdm5c Causes Spurious Transcription and Prevents the Fine-Tuning of Activity-Regulated Enhancers in Neurons

(2017) Marilyn Scandaglia et al.   Cell Reports

Functional convergence of histone methyltransferases EHMT1 and KMT2C involved in intellectual disability and autism spectrum disorder

(2017) Tom S. Koemans et al.   PLoS Genetics

Haploinsufficiency of KMT2B , Encoding the Lysine-Specific Histone Methyltransferase 2B, Results in Early-Onset Generalized Dystonia

(2016) Michael Zech et al.   AMERICAN JOURNAL OF HUMAN GENETICS

BioEssays 1∕2017

(2016)   BIOESSAYS

Epigenetic transcriptional memory

(2016) Agustina D’Urso et al.   CURRENT GENETICS

EPOP Interacts with Elongin BC and USP7 to Modulate the Chromatin Landscape

(2016) Robert Liefke et al.   MOLECULAR CELL

Mutations in the histone methyltransferase gene KMT2B cause complex early-onset dystonia

(2016) Esther Meyer et al.   NATURE GENETICS

Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders

(2016) Tarjinder Singh et al.   NATURE NEUROSCIENCE

Neuronal Deletion of Kmt2a/Mll1 Histone Methyltransferase in Ventral Striatum is Associated with Defective Spike-Timing-Dependent Striatal Synaptic Plasticity, Altered Response to Dopaminergic Drugs and Increased Anxiety

(2016) Erica Y Shen et al.   NEUROPSYCHOPHARMACOLOGY

Set1/COMPASS and Mediator are repurposed to promote epigenetic transcriptional memory

(2016) Agustina D'Urso et al.   eLife

Gene discovery for Mendelian conditions via social networking: de novo variants in KDM1A cause developmental delay and distinctive facial features

(2015) Jessica X. Chong et al.   GENETICS IN MEDICINE

Neuronal Kmt2a/Mll1 Histone Methyltransferase Is Essential for Prefrontal Synaptic Plasticity and Working Memory

(2015) M. Jakovcevski et al.   JOURNAL OF NEUROSCIENCE

An Interactive Database for the Assessment of Histone Antibody Specificity

(2015) Scott B. Rothbart et al.   MOLECULAR CELL

Broad H3K4me3 is associated with increased transcription elongation and enhancer activity at tumor-suppressor genes

(2015) Kaifu Chen et al.   NATURE GENETICS

ChIPmentation: fast, robust, low-input ChIP-seq for histones and transcription factors

(2015) Christian Schmidl et al.   NATURE METHODS

DNA methylation changes in plasticity genes accompany the formation and maintenance of memory

(2015) Rashi Halder et al.   NATURE NEUROSCIENCE

Disrupted intricacy of histone H3K4 methylation in neurodevelopmental disorders

(2015) Christina N Vallianatos et al.   Epigenomics

Deciphering H3K4me3 broad domains associated with gene-regulatory networks and conserved epigenomic landscapes in the human brain

(2015) A Dincer et al.   Translational Psychiatry

De novoANKRD11andKDM1Agene mutations in a male with features of KBG syndrome and Kabuki syndrome

(2014) Sanjin Tunovic et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

H3K4me3 Breadth Is Linked to Cell Identity and Transcriptional Consistency

(2014) Bérénice A. Benayoun et al.   CELL

Synaptic, transcriptional and chromatin genes disrupted in autism

(2014) Silvia De Rubeis et al.   NATURE

The contribution of de novo coding mutations to autism spectrum disorder

(2014) Ivan Iossifov et al.   NATURE

Analysis of nascent RNA identifies a unified architecture of initiation regions at mammalian promoters and enhancers

(2014) Leighton J Core et al.   NATURE GENETICS

Loss-of-Function Variants in Schizophrenia Risk and SETD1A as a Candidate Susceptibility Gene

(2014) Atsushi Takata et al.   NEURON

Regulation of histone H3K4 methylation in brain development and disease

(2014) E. Shen et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

De Novo Insertions and Deletions of Predominantly Paternal Origin Are Associated with Autism Spectrum Disorder

(2014) Shan Dong et al.   Cell Reports

MLL2 and KDM6A mutations in patients with Kabuki syndrome

(2013) Noriko Miyake et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Methamphetamine-Associated Memory Is Regulated by a Writer and an Eraser of Permissive Histone Methylation

(2013) Argel Aguilar-Valles et al.   BIOLOGICAL PSYCHIATRY

H3K4me3 Interactions with TAF3 Regulate Preinitiation Complex Assembly and Selective Gene Activation

(2013) Shannon M. Lauberth et al.   CELL

Protein Analysis by Shotgun/Bottom-up Proteomics

(2013) Yaoyang Zhang et al.   CHEMICAL REVIEWS

Histone-Methyltransferase MLL2 (KMT2B) Is Required for Memory Formation in Mice

(2013) C. Kerimoglu et al.   JOURNAL OF NEUROSCIENCE

Histone H3 lysine methylation in cognition and intellectual disability disorders

(2013) S. Parkel et al.   LEARNING & MEMORY

The Emerging Field of Neuroepigenetics

(2013) J. David Sweatt   NEURON

Targeting H3K4 trimethylation in Huntington disease

(2013) M. Vashishtha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Conserved Role for Human Nup98 in Altering Chromatin Structure and Promoting Epigenetic Transcriptional Memory

(2013) William H. Light et al.   PLOS BIOLOGY

De Novo Mutations in MLL Cause Wiedemann-Steiner Syndrome

(2012) Wendy D. Jones et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Disruption of an EHMT1-Associated Chromatin-Modification Module Causes Intellectual Disability

(2012) Tjitske Kleefstra et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The COMPASS Family of Histone H3K4 Methylases: Mechanisms of Regulation in Development and Disease Pathogenesis

(2012) Ali Shilatifard   Annual Review of Biochemistry

Transcription in the Absence of Histone H3.2 and H3K4 Methylation

(2012) Martina Hödl et al.   CURRENT BIOLOGY

Cfp1 integrates both CpG content and gene activity for accurate H3K4me3 deposition in embryonic stem cells

(2012) T. Clouaire et al.   GENES & DEVELOPMENT

High-Affinity, Small-Molecule Peptidomimetic Inhibitors of MLL1/WDR5 Protein–Protein Interaction

(2012) Hacer Karatas et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A map of the cis-regulatory sequences in the mouse genome

(2012) Yin Shen et al.   NATURE

Human-Specific Histone Methylation Signatures at Transcription Start Sites in Prefrontal Neurons

(2012) Hennady P. Shulha et al.   PLOS BIOLOGY

Epigenetic Signatures of Autism

(2011) Hennady P. Shulha   ARCHIVES OF GENERAL PSYCHIATRY

The COMPASS Family of H3K4 Methylases in Drosophila

(2011) M. Mohan et al.   MOLECULAR AND CELLULAR BIOLOGY

Deep sequencing reveals 50 novel genes for recessive cognitive disorders

(2011) Hossein Najmabadi et al.   NATURE

Mapping and analysis of chromatin state dynamics in nine human cell types

(2011) Jason Ernst et al.   NATURE

Epigenetic Mechanisms in Cognition

(2011) Jeremy J. Day et al.   NEURON

Histone Methylation Regulates Memory Formation

(2010) S. Gupta et al.   JOURNAL OF NEUROSCIENCE

Gamma Interferon-Dependent Transcriptional Memory via Relocalization of a Gene Locus to PML Nuclear Bodies

(2010) M. Gialitakis et al.   MOLECULAR AND CELLULAR BIOLOGY

CpG islands influence chromatin structure via the CpG-binding protein Cfp1

(2010) John P. Thomson et al.   NATURE

Widespread transcription at neuronal activity-regulated enhancers

(2010) Tae-Kyung Kim et al.   NATURE

Exome sequencing identifies MLL2 mutations as a cause of Kabuki syndrome

(2010) Sarah B Ng et al.   NATURE GENETICS

DNA methylation and memory formation

(2010) Jeremy J Day et al.   NATURE NEUROSCIENCE

Histone H3K27ac separates active from poised enhancers and predicts developmental state

(2010) M. P. Creyghton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone modifications at human enhancers reflect global cell-type-specific gene expression

(2009) Nathaniel D. Heintzman et al.   NATURE

Isolation of neuronal chromatin from brain tissue

(2008) Yan Jiang et al.   BMC NEUROSCIENCE

Histone H3 lysine 4 trimethylation marks meiotic recombination initiation sites

(2008) Valérie Borde et al.   EMBO JOURNAL

Histone H3K4me3 Binding Is Required for the DNA Repair and Apoptotic Activities of ING1 Tumor Suppressor

(2008) P.V. Peña et al.   JOURNAL OF MOLECULAR BIOLOGY

Molecular Regulation of H3K4 Trimethylation by Wdr82, a Component of Human Set1/COMPASS

(2008) M. Wu et al.   MOLECULAR AND CELLULAR BIOLOGY