Epigenetics in age-related macular degeneration: new discoveries and future perspectives
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Epigenetics in age-related macular degeneration: new discoveries and future perspectives
Authors
Keywords
-
Journal
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume 77, Issue 5, Pages 807-818
Publisher
Springer Science and Business Media LLC
Online
2020-01-03
DOI
10.1007/s00018-019-03421-w
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Chromatin accessibility and the regulatory epigenome
- (2019) Sandy L. Klemm et al. NATURE REVIEWS GENETICS
- Epigenetics, microbiota, and intraocular inflammation: New paradigms of immune regulation in the eye
- (2018) Xiaofeng Wen et al. PROGRESS IN RETINAL AND EYE RESEARCH
- ATAC-Seq analysis reveals a widespread decrease of chromatin accessibility in age-related macular degeneration
- (2018) Jie Wang et al. Nature Communications
- Transposable elements are regulated by context-specific patterns of chromatin marks in mouse embryonic stem cells
- (2018) Jiangping He et al. Nature Communications
- Genetics and genetic testing for age-related macular degeneration
- (2017) A. Warwick et al. EYE
- From compliment to insult: genetics of the complement system in physiology and disease in the human retina
- (2017) Robert F. Mullins et al. HUMAN MOLECULAR GENETICS
- Transposable Element Exaptation into Regulatory Regions Is Rare, Influenced by Evolutionary Age, and Subject to Pleiotropic Constraints
- (2017) Corinne N. Simonti et al. MOLECULAR BIOLOGY AND EVOLUTION
- THE PATHOPHYSIOLOGY OF GEOGRAPHIC ATROPHY SECONDARY TO AGE-RELATED MACULAR DEGENERATION AND THE COMPLEMENT PATHWAY AS A THERAPEUTIC TARGET
- (2017) David S. Boyer et al. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
- Differential Accumulation of Secreted AβPP Metabolites in Ocular Fluids
- (2017) Annamalai Prakasam et al. JOURNAL OF ALZHEIMERS DISEASE
- The role of sirtuins in aging and age-related diseases
- (2016) Mateusz Wątroba et al. Advances in Medical Sciences
- DNA methylation-based measures of biological age: meta-analysis predicting time to death
- (2016) Brian H. Chen et al. Aging-US
- Exploring the read-write genome: mobile DNA and mammalian adaptation
- (2016) James A. Shapiro CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Long Terminal Repeats: From Parasitic Elements to Building Blocks of the Transcriptional Regulatory Repertoire
- (2016) Peter J. Thompson et al. MOLECULAR CELL
- TLR4 inhibitor attenuates amyloid-β-induced angiogenic and inflammatory factors in ARPE-19 cells: Implications for age-related macular degeneration
- (2016) LI CHEN et al. Molecular Medicine Reports
- Regulatory activities of transposable elements: from conflicts to benefits
- (2016) Edward B. Chuong et al. NATURE REVIEWS GENETICS
- New Insights into the Regulation of Heterochromatin
- (2016) Jiyong Wang et al. TRENDS IN GENETICS
- Frailty is associated with the epigenetic clock but not with telomere length in a German cohort
- (2016) Lutz Philipp Breitling et al. Clinical Epigenetics
- Increased epigenetic age and granulocyte counts in the blood of Parkinson's disease patients
- (2015) Steve Horvath et al. Aging-US
- DNA methylation age of blood predicts future onset of lung cancer in the women's health initiative
- (2015) Morgan E. Levine et al. Aging-US
- Dynamic Transcription of Distinct Classes of Endogenous Retroviral Elements Marks Specific Populations of Early Human Embryonic Cells
- (2015) Jonathan Göke et al. Cell Stem Cell
- Functional single nucleotide polymorphism inIL−17A3′ untranslated region is targeted by miR-4480 in vitro and may be associated with age-related macular degeneration
- (2015) Nicholas A. Popp et al. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
- Differential DNA methylation identified in the blood and retina of AMD patients
- (2015) Verity F Oliver et al. Epigenetics
- Dementia of the eye: the role of amyloid beta in retinal degeneration
- (2015) J A Ratnayaka et al. EYE
- The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936
- (2015) Riccardo E Marioni et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Conrad Waddington and the origin of epigenetics
- (2015) D. Noble JOURNAL OF EXPERIMENTAL BIOLOGY
- microRNA-33 Regulates ApoE Lipidation and Amyloid- Metabolism in the Brain
- (2015) J. Kim et al. JOURNAL OF NEUROSCIENCE
- MRZ-99030 – A novel modulator of Aβ aggregation: I – Mechanism of action (MoA) underlying the potential neuroprotective treatment of Alzheimer's disease, glaucoma and age-related macular degeneration (AMD)
- (2015) Christopher G. Parsons et al. NEUROPHARMACOLOGY
- Oxidative Stress Induces Biphasic ERK1/2 Activation in the RPE with Distinct Effects on Cell Survival at Early and Late Activation
- (2014) Stefan Koinzer et al. CURRENT EYE RESEARCH
- Epigenetic modifications as potential therapeutic targets in age-related macular degeneration and diabetic retinopathy
- (2014) Faith A.A. Kwa et al. DRUG DISCOVERY TODAY
- (Epi)Genetic Analyses of Age-Related Macular Degeneration: Case-Control and Discordant Twin Studies
- (2014) John N. Hutchinson et al. HUMAN HEREDITY
- PRMT5 Protects Genomic Integrity during Global DNA Demethylation in Primordial Germ Cells and Preimplantation Embryos
- (2014) Shinseog Kim et al. MOLECULAR CELL
- IL-18 is not therapeutic for neovascular age-related macular degeneration
- (2014) Yoshio Hirano et al. NATURE MEDICINE
- High-resolution digital profiling of the epigenome
- (2014) Gabriel E. Zentner et al. NATURE REVIEWS GENETICS
- Intracellular amyloid beta alters the tight junction of retinal pigment epithelium in 5XFAD mice
- (2014) Sung Wook Park et al. NEUROBIOLOGY OF AGING
- Reorganization of Visual Processing in Age-Related Macular Degeneration Depends on Foveal Loss
- (2014) Daniel D. Dilks et al. OPTOMETRY AND VISION SCIENCE
- The RIDL hypothesis: transposable elements as functional domains of long noncoding RNAs
- (2014) R. Johnson et al. RNA
- Mapping Human Epigenomes
- (2013) Chloe M. Rivera et al. CELL
- Chromatin signatures and retrotransposon profiling in mouse embryos reveal regulation of LINE-1 by RNA
- (2013) Anas Fadloun et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The Majority of Primate-Specific Regulatory Sequences Are Derived from Transposable Elements
- (2013) Pierre-Étienne Jacques et al. PLoS Genetics
- DNA methylation age of human tissues and cell types
- (2013) Steve Horvath GENOME BIOLOGY
- Sirtuin activators and inhibitors
- (2012) José M. Villalba et al. BIOFACTORS
- DICER1 Loss and Alu RNA Induce Age-Related Macular Degeneration via the NLRP3 Inflammasome and MyD88
- (2012) Valeria Tarallo et al. CELL
- Age-related macular degeneration
- (2012) Laurence S Lim et al. LANCET
- Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates
- (2012) Gregory Hannum et al. MOLECULAR CELL
- NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components
- (2012) Sarah L Doyle et al. NATURE MEDICINE
- EXPRESSION OF SIRT1 IN CHOROIDAL NEOVASCULAR MEMBRANES
- (2012) Shawn C. Maloney et al. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
- Hypomethylation of the IL17RC Promoter Associates with Age-Related Macular Degeneration
- (2012) Lai Wei et al. Cell Reports
- DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration
- (2011) Hiroki Kaneko et al. NATURE
- Age-related macular degeneration with discordant late stage phenotypes in monozygotic twins
- (2011) Claudia N. Keilhauer et al. OPHTHALMIC GENETICS
- MicroRNA-21 Exhibits Antiangiogenic Function by Targeting RhoB Expression in Endothelial Cells
- (2011) Céline Sabatel et al. PLoS One
- Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease risk
- (2011) M. Heurich et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Characterisation of amyloid-induced inflammatory responses in the rat retina
- (2011) D. R. Howlett et al. EXPERIMENTAL BRAIN RESEARCH
- Inflammatory cytokines regulate microRNA-155 expression in human retinal pigment epithelial cells by activating JAK/STAT pathway
- (2010) R. Krishnan Kutty et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Folic Acid, Pyridoxine, and Cyanocobalamin Combination Treatment and Age-Related Macular Degeneration in Women
- (2009) William G. Christen et al. ARCHIVES OF INTERNAL MEDICINE
- Src homology 2 domain-containing inositol-5-phosphatase and CCAAT enhancer-binding protein are targeted by miR-155 in B cells of E -MiR-155 transgenic mice
- (2009) S. Costinean et al. BLOOD
- An operational definition of epigenetics
- (2009) S. L. Berger et al. GENES & DEVELOPMENT
- Histone H2AX is integral to hypoxia-driven neovascularization
- (2009) Matina Economopoulou et al. NATURE MEDICINE
- Biogenesis of small RNAs in animals
- (2009) V. Narry Kim et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Inositol phosphatase SHIP1 is a primary target of miR-155
- (2009) R. M. O'Connell et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Para-inflammation in the aging retina
- (2009) Heping Xu et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Genetics, epigenetics and pharmaco-(epi)genomics in angiogenesis
- (2008) Ian Buysschaert et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- MicroRNAs Regulate Ocular Neovascularization
- (2008) JiKui Shen et al. MOLECULAR THERAPY
- Gene–environment interactions in ocular diseases
- (2008) S.C. Sacca et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started