Application of atomic force microscopy in cancer research

Applications of high-speed atomic force microscopy to real-time visualization of dynamic biomolecular processes

(2018) Takayuki Uchihashi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Microfluidic chip for non-invasive analysis of tumor cells interaction with anti-cancer drug doxorubicin by AFM and Raman spectroscopy

(2018) Han Zhang et al.   Biomicrofluidics

Circular RNAs (circRNAs) in cancer

(2018) Ruoyu Zhou et al.   CANCER LETTERS

Role of metabolism in cancer cell radioresistance and radiosensitization methods

(2018) Le Tang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Function of the c-Met receptor tyrosine kinase in carcinogenesis and associated therapeutic opportunities

(2018) Yazhuo Zhang et al.   Molecular Cancer

LncRNAs regulate the cytoskeleton and related Rho/ROCK signaling in cancer metastasis

(2018) Yanyan Tang et al.   Molecular Cancer

Circular RNAs function as ceRNAs to regulate and control human cancer progression

(2018) Yaxian Zhong et al.   Molecular Cancer

BPIFB1 (LPLUNC1) inhibits radioresistance in nasopharyngeal carcinoma by inhibiting VTN expression

(2018) Fang Wei et al.   Cell Death & Disease

Long non-coding RNA PVT1 predicts poor prognosis and induces radioresistance by regulating DNA repair and cell apoptosis in nasopharyngeal carcinoma

(2018) Yi He et al.   Cell Death & Disease

Small size fullerenol nanoparticles suppress lung metastasis of breast cancer cell by disrupting actin dynamics

(2018) Yanxia Qin et al.   JOURNAL OF NANOBIOTECHNOLOGY

Identification of genomic alterations in nasopharyngeal carcinoma and nasopharyngeal carcinoma-derived Epstein–Barr virus by whole-genome sequencing

(2018) Chaofeng Tu et al.   CARCINOGENESIS

Mapping heterogeneity of cellular mechanics by multi-harmonic atomic force microscopy

(2018) Yuri M. Efremov et al.   Nature Protocols

The emerging role of Epstein-Barr virus encoded microRNAs in nasopharyngeal carcinoma

(2018) Chunmei Fan et al.   Journal of Cancer

Long non-coding RNA LOC284454 promotes migration and invasion of nasopharyngeal carcinoma via modulating the Rho/Rac signaling pathway

(2018) Chunmei Fan et al.   CARCINOGENESIS

Long noncoding RNA AFAP1-AS1 acts as a competing endogenous RNA of miR-423-5p to facilitate nasopharyngeal carcinoma metastasis through regulating the Rho/Rac pathway

(2018) Yu Lian et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Effects of tumor metabolic microenvironment on regulatory T cells

(2018) Yi-an Wang et al.   Molecular Cancer

The selective cytotoxicity of DSF-Cu attributes to the biomechanical properties and cytoskeleton rearrangements in the normal and cancerous nasopharyngeal epithelial cells

(2017) Yaping Yang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

circGFRA1 and GFRA1 act as ceRNAs in triple negative breast cancer by regulating miR-34a

(2017) Rongfang He et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Alpha-enolase (ENO1) controls alpha v/beta 3 integrin expression and regulates pancreatic cancer adhesion, invasion, and metastasis

(2017) Moitza Principe et al.   Journal of Hematology & Oncology

Role of long non-coding RNAs in glucose metabolism in cancer

(2017) Chunmei Fan et al.   Molecular Cancer

Circular RNAs in human cancer

(2017) Yumin Wang et al.   Molecular Cancer

Imaging modes of atomic force microscopy for application in molecular and cell biology

(2017) Yves F. Dufrêne et al.   Nature Nanotechnology

Trend analysis of cancer incidence and mortality in China

(2017) Fang Wei et al.   Science China-Life Sciences

Upregulated long non-coding RNA LINC00152 expression is associated with progression and poor prognosis of tongue squamous cell carcinoma

(2017) Jianjun Yu et al.   Journal of Cancer

Real-time, label-free monitoring of cell viability based on cell adhesion measurements with an atomic force microscope

(2017) Fang Yang et al.   JOURNAL OF NANOBIOTECHNOLOGY

Effect of Actin Organization on the Stiffness of Living Breast Cancer Cells Revealed by Peak-Force Modulation Atomic Force Microscopy

(2016) Alicia Calzado-Martín et al.   ACS Nano

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

TSC22D2 interacts with PKM2 and inhibits cell growth in colorectal cancer

(2016) Fang Liang et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Probing Micromechanical Properties of the Extracellular Matrix of Soft Tissues by Atomic Force Microscopy

(2016) Ignasi Jorba et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Visualization and Quantification of MicroRNA in a Single Cell Using Atomic Force Microscopy

(2016) Hyunseo Koo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Spatiotemporal dynamics of the nuclear pore complex transport barrier resolved by high-speed atomic force microscopy

(2016) Yusuke Sakiyama et al.   Nature Nanotechnology

Yttrium-90 radioembolization for colorectal cancer liver metastases in KRAS wild-type and mutant patients: Clinical and ccfDNA studies

(2016) E. Janowski et al.   ONCOLOGY REPORTS

RETRACTED: Diagnosis of cervical cancer cell taken from scanning electron and atomic force microscope images of the same patients using discrete wavelet entropy energy and Jensen Shannon, Hellinger, Triangle Measure classifier

(2016) Sevcan Aytac Korkmaz   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Yeast two-hybrid screening identified WDR77 as a novel interacting partner of TSC22D2

(2016) Qiao Li et al.   TUMOR BIOLOGY

Epstein-Barr virus-encoded miR-BART6-3p inhibits cancer cell metastasis and invasion by targeting long non-coding RNA LOC553103

(2016) Baoyu He et al.   Cell Death & Disease

Combined strategies for optimal detection of the contact point in AFM force-indentation curves obtained on thin samples and adherent cells

(2016) Núria Gavara   Scientific Reports

Genome-wide Analysis of Epstein-Barr Virus (EBV) Integration and Strain in C666-1 and Raji Cells

(2016) Kai Xiao et al.   Journal of Cancer

The Long Noncoding RNA MALAT-1 is A Novel Biomarker in Various Cancers: A Meta-analysis Based on the GEO Database and Literature

(2016) Yumin Wang et al.   Journal of Cancer

Label-free identification and characterization of living human primary and secondary tumour cells

(2015) Dimitrios Tsikritsis et al.   ANALYST

MicroRNA Detection: Current Technology and Research Strategies

(2015) Eric A. Hunt et al.   Annual Review of Analytical Chemistry

Alpha-enolase promotes cell glycolysis, growth, migration, and invasion in non-small cell lung cancer through FAK-mediated PI3K/AKT pathway

(2015) Qiao-Fen Fu et al.   Journal of Hematology & Oncology

Papillary thyroid cancer–derived exosomes contain miRNA-146b and miRNA-222

(2015) James C. Lee et al.   JOURNAL OF SURGICAL RESEARCH

Exosome-mediated microRNA signaling from breast cancer cells is altered by the anti-angiogenesis agent docosahexaenoic acid (DHA)

(2015) Bethany N. Hannafon et al.   Molecular Cancer

An Atomic Force Microscope Study Revealed Two Mechanisms in the Effect of Anticancer Drugs on Rate-Dependent Young’s Modulus of Human Prostate Cancer Cells

(2015) Juan Ren et al.   PLoS One

An integrative transcriptomic analysis reveals p53 regulated miRNA, mRNA, and lncRNA networks in nasopharyngeal carcinoma

(2015) Zhaojian Gong et al.   TUMOR BIOLOGY

Targeting of surface alpha-enolase inhibits the invasiveness of pancreatic cancer cells

(2015) Moitza Principe et al.   Oncotarget

Fast, multi-frequency and quantitative nanomechanical mapping of live cells using the atomic force microscope

(2015) Alexander X. Cartagena-Rivera et al.   Scientific Reports

A highly efficient flexible dye-sensitized solar cell based on nickel sulfide/platinum/titanium counter electrode

(2015) Gentian Yue et al.   Nanoscale Research Letters

Combined Clsm and AFM Indentation Reveals Metastatic Cancer Cells Stiffen during Rho/ROCK Contractility-Dependent Invasion of Collagen I Matrices

(2015) Jack R. Staunton et al.   BIOPHYSICAL JOURNAL

Lapatinib-incorporated lipoprotein-like nanoparticles: preparation and a proposed breast cancer-targeting mechanism

(2014) Li Zhang et al.   ACTA PHARMACOLOGICA SINICA

Toehold-initiated Rolling Circle Amplification for Visualizing Individual MicroRNAs In Situ in Single Cells

(2014) Ruijie Deng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Local Viscoelastic Properties of Live Cells Investigated Using Dynamic and Quasi-Static Atomic Force Microscopy Methods

(2014) Alexander Cartagena et al.   BIOPHYSICAL JOURNAL

Cancer Exosomes Perform Cell-Independent MicroRNA Biogenesis and Promote Tumorigenesis

(2014) Sonia A. Melo et al.   CANCER CELL

Filming Biomolecular Processes by High-Speed Atomic Force Microscopy

(2014) Toshio Ando et al.   CHEMICAL REVIEWS

Ultrastable atomic force microscopy: Improved force and positional stability

(2014) Allison B. Churnside et al.   FEBS LETTERS

Cdx1 and Cdx2 Function as Tumor Suppressors

(2014) Alexa Hryniuk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alpha-enolase as a potential cancer prognostic marker promotes cell growth, migration, and invasion in glioma

(2014) Ye Song et al.   Molecular Cancer

Multi-marker analysis of circulating cell-free DNA toward personalized medicine for colorectal cancer

(2014) Florent Mouliere et al.   Molecular Oncology

Evaluation of quantitative miRNA expression platforms in the microRNA quality control (miRQC) study

(2014) Pieter Mestdagh et al.   NATURE METHODS

Exosomes from docetaxel-resistant breast cancer cells alter chemosensitivity by delivering microRNAs

(2014) Wei-xian Chen et al.   TUMOR BIOLOGY

Cell mechanics: principles, practices, and prospects

(2014) Emad Moeendarbary et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

The Impact of Extracellular Vesicle-Encapsulated Circulating MicroRNAs in Lung Cancer Research

(2014) Yu Fujita et al.   Biomed Research International

Anticancer drug-loaded multifunctional nanoparticles to enhance the chemotherapeutic efficacy in lung cancer metastasis

(2014) Jian-Ting Long et al.   JOURNAL OF NANOBIOTECHNOLOGY

Review on Cell Mechanics: Experimental and Modeling Approaches

(2013) Marita L. Rodriguez et al.   Applied Mechanics Reviews

The Effect of the Endothelial Cell Cortex on Atomic Force Microscopy Measurements

(2013) R. Vargas-Pinto et al.   BIOPHYSICAL JOURNAL

MicroRNA: Function, Detection, and Bioanalysis

(2013) Haifeng Dong et al.   CHEMICAL REVIEWS

Atomic force microscopy: High resolution dynamic imaging of cellular and molecular structure in health and disease

(2013) Douglas J. Taatjes et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Bio-modified carbon nanoparticles loaded with methotrexate Possible carrier for anticancer drug delivery

(2013) Thangavelu Muthukumar et al.   Materials Science & Engineering C-Materials for Biological Applications

Structural impact of cations on lipid bilayer models: Nanomechanical properties by AFM-force spectroscopy

(2013) Lorena Redondo-Morata et al.   MOLECULAR MEMBRANE BIOLOGY

Force nanoscopy of cell mechanics and cell adhesion

(2013) Yves F. Dufrêne et al.   Nanoscale

The causes and consequences of genetic heterogeneity in cancer evolution

(2013) Rebecca A. Burrell et al.   NATURE

Influence of tumour micro-environment heterogeneity on therapeutic response

(2013) Melissa R. Junttila et al.   NATURE

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

Surface α-Enolase Promotes Extracellular Matrix Degradation and Tumor Metastasis and Represents a New Therapeutic Target

(2013) Kuan-Chung Hsiao et al.   PLoS One

Wide-area scanner for high-speed atomic force microscopy

(2013) Hiroki Watanabe et al.   REVIEW OF SCIENTIFIC INSTRUMENTS

Brain Tumor Classification Using AFM in Combination with Data Mining Techniques

(2013) Marlene Huml et al.   Biomed Research International

Disulfiram: An Old Therapeutic with New Applications

(2012) Kelly Barth et al.   CNS & Neurological Disorders-Drug Targets

α-Enolase, a Multifunctional Protein: Its Role on Pathophysiological Situations

(2012) Àngels Díaz-Ramos et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Glyphosate-induced stiffening of HaCaT keratinocytes, a Peak Force Tapping study on living cells

(2012) Celine Heu et al.   JOURNAL OF STRUCTURAL BIOLOGY

Behavior and anti-glioma effect of lapatinib-incorporated lipoprotein-like nanoparticles

(2012) Huile Gao et al.   NANOTECHNOLOGY

The microcosmos of cancer

(2012) Amaia Lujambio et al.   NATURE

The nanomechanical signature of breast cancer

(2012) Marija Plodinec et al.   Nature Nanotechnology

Cell Stiffness Is a Biomarker of the Metastatic Potential of Ovarian Cancer Cells

(2012) Wenwei Xu et al.   PLoS One

Collaborative interplay between FGF-2 and VEGF-C promotes lymphangiogenesis and metastasis

(2012) R. Cao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Curcumin induced nanoscale CD44 molecular redistribution and antigen–antibody interaction on HepG2 cell surface

(2011) Mu Wang et al.   ANALYTICA CHIMICA ACTA

Linear and Nonlinear Rheology of Living Cells

(2011) Philip Kollmannsberger et al.   Annual Review of Materials Research

Single-step direct measurement of amyloid fibrils stiffness by peak force quantitative nanomechanical atomic force microscopy

(2011) Jozef Adamcik et al.   APPLIED PHYSICS LETTERS

Cancer cell detection in tissue sections using AFM

(2011) Małgorzata Lekka et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The role of nuclear pore complex in tumor microenvironment and metastasis

(2011) Tatsuyoshi Funasaka et al.   CANCER AND METASTASIS REVIEWS

The Dual EGFR/HER2 Inhibitor Lapatinib Synergistically Enhances the Antitumor Activity of the Histone Deacetylase Inhibitor Panobinostat in Colorectal Cancer Models

(2011) M. J. LaBonte et al.   CANCER RESEARCH

Force nanoscopy of living cells

(2011) Daniel J. Müller et al.   CURRENT BIOLOGY

Targeting Malignancies with Disulfiram (Antabuse): Multidrug Resistance, Angiogenesis, and Proteasome

(2011) B. Cvek   CURRENT CANCER DRUG TARGETS

α-enolase: a promising therapeutic and diagnostic tumor target

(2011) Michela Capello et al.   FEBS Journal

Nanopore-based detection of circulating microRNAs in lung cancer patients

(2011) Yong Wang et al.   Nature Nanotechnology

Binding of blood proteins to carbon nanotubes reduces cytotoxicity

(2011) C. Ge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-Speed Atomic Force Microscopy Reveals Rotary Catalysis of Rotorless F1-ATPase

(2011) T. Uchihashi et al.   SCIENCE

Multidimensional Atomic Force Microscopy: A Versatile Novel Technology for Nanopharmacology Research

(2010) Ratnesh Lal et al.   AAPS Journal

Direct Quantification of Single-Molecules of MicroRNA by Total Internal Reflection Fluorescence Microscopy

(2010) Ho-Man Chan et al.   ANALYTICAL CHEMISTRY

Fluorescent Metal Nanoshell Probe to Detect Single miRNA in Lung Cancer Cell

(2010) Jian Zhang et al.   ANALYTICAL CHEMISTRY

A distinctive role for focal adhesion proteins in three-dimensional cell motility

(2010) Stephanie I. Fraley et al.   NATURE CELL BIOLOGY

Kinetics of antimicrobial peptide activity measured on individual bacterial cells using high-speed atomic force microscopy

(2010) Georg E. Fantner et al.   Nature Nanotechnology

Rapid electronic detection of probe-specific microRNAs using thin nanopore sensors

(2010) Meni Wanunu et al.   Nature Nanotechnology

Vibrational spectroscopy: a clinical tool for cancer diagnostics

(2009) Catherine Kendall et al.   ANALYST

Atomic force microscope study of tumor cell membranes following treatment with anti-cancer drugs

(2009) Jinyi Wang et al.   BIOSENSORS & BIOELECTRONICS

Characterization of a rituximab variant with potent antitumor activity against rituximab-resistant B-cell lymphoma

(2009) B. Li et al.   BLOOD

Tumor suppressor protein SMAR1 modulates the roughness of cell surface: combined AFM and SEM study

(2009) Ruchika Kaul-Ghanekar et al.   BMC CANCER

Atomic force microscopy: a tool to study the structure, dynamics and stability of liposomal drug delivery systems

(2009) Ellas Spyratou et al.   Expert Opinion on Drug Delivery

Effect of AEE788 and/or Celecoxib on colon cancer cell morphology using advanced microscopic techniques

(2009) P. Venkatesan et al.   MICRON

Measuring microenvironment mechanical stress of rat liver during diethylnitrosamine induced hepatocarcinogenesis by atomic force microscope

(2009) Zhao Gang et al.   MICROSCOPY RESEARCH AND TECHNIQUE

Ultrastable Atomic Force Microscopy: Atomic-Scale Stability and Registration in Ambient Conditions

(2009) Gavin M. King et al.   NANO LETTERS

Force probing surfaces of living cells to molecular resolution

(2009) Daniel J Müller et al.   Nature Chemical Biology

Imaging individual microRNAs in single mammalian cells in situ

(2009) J. Lu et al.   NUCLEIC ACIDS RESEARCH

Synergistic proapoptotic effects of the two tyrosine kinase inhibitors pazopanib and lapatinib on multiple carcinoma cell lines

(2009) K A Olaussen et al.   ONCOGENE

Lymphangiogenesis and Its Relationship With Lymphatic Metastasis and Prognosis in Malignant Melanoma

(2008) Baoquan Liu et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

AFM indentation study of breast cancer cells

(2008) Q.S. Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Quantitative cellular uptake, localization and cytotoxicity of curcumin in normal and tumor cells

(2008) A. Kunwar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Specificity and affinity of human Fc  receptors and their polymorphic variants for human IgG subclasses

(2008) P. Bruhns et al.   BLOOD

Curcumin: From ancient medicine to current clinical trials

(2008) H. Hatcher et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Specific recognition of RNA/DNA hybrid and enhancement of human RNase H1 activity by HBD

(2008) Marcin Nowotny et al.   EMBO JOURNAL

AFM-based analysis of human metastatic cancer cells

(2008) Sarah E Cross et al.   NANOTECHNOLOGY