SPAG5‐AS1 inhibited autophagy and aggravated apoptosis of podocytes via SPAG5/AKT/mTOR pathway

Endothelial Leptin Receptor Deletion Promotes Cardiac Autophagy and Angiogenesis Following Pressure Overload by Suppressing Akt/mTOR Signaling

(2019) Rajinikanth Gogiraju et al.   Circulation-Heart Failure

Exosome secreted from adipose-derived stem cells attenuates diabetic nephropathy by promoting autophagy flux and inhibiting apoptosis in podocyte

(2019) Juan Jin et al.   Stem Cell Research & Therapy

Increased expression of lncRNA CASC9 promotes tumor progression by suppressing autophagy-mediated cell apoptosis via the AKT/mTOR pathway in oral squamous cell carcinoma

(2019) Yixin Yang et al.   Cell Death & Disease

SPAG5 upregulation contributes to enhanced c-MYC transcriptional activity via interaction with c-MYC binding protein in triple-negative breast cancer

(2019) Ming Li et al.   Journal of Hematology & Oncology

Long noncoding RNA CDKN2B-AS1 interacts with transcription factor BCL11A to regulate progression of cerebral infarction through mediating MAP4K1 transcription

(2019) Jun-Jie Lei et al.   FASEB JOURNAL

Podocytes and autophagy: a potential therapeutic target in lupus nephritis

(2019) Xu-Jie Zhou et al.   Autophagy

FOXP1-induced lncRNA CLRN1-AS1 acts as a tumor suppressor in pituitary prolactinoma by repressing the autophagy via inactivating Wnt/β-catenin signaling pathway

(2019) Chao Wang et al.   Cell Death & Disease

Silencing of long noncoding RNA PVT1 inhibits podocyte damage and apoptosis in diabetic nephropathy by upregulating FOXA1

(2019) Dong-Wei Liu et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Long Noncoding RNA LINC01619 Regulates MicroRNA-27a/Forkhead Box Protein O1 and Endoplasmic Reticulum Stress-Mediated Podocyte Injury in Diabetic Nephropathy

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Long non-coding RNA SNHG15 interacts with and stabilizes transcription factor Slug and promotes colon cancer progression

(2018) Hao Jiang et al.   CANCER LETTERS

The lncRNA MACC1-AS1 promotes gastric cancer cell metabolic plasticity via AMPK/Lin28 mediated mRNA stability of MACC1

(2018) Yang Zhao et al.   Molecular Cancer

Long noncoding RNA OCC-1 suppresses cell growth through destabilizing HuR protein in colorectal cancer

(2018) Yang Lan et al.   NUCLEIC ACIDS RESEARCH

SPAG5 promotes proliferation and suppresses apoptosis in bladder urothelial carcinoma by upregulating Wnt3 via activating the AKT/mTOR pathway and predicts poorer survival

(2018) J. Y. Liu et al.   ONCOGENE

Association of Salivary MicroRNA Changes With Prolonged Concussion Symptoms

(2018) Jeremiah J. Johnson et al.   JAMA Pediatrics

SPAG5 promotes hepatocellular carcinoma progression by downregulating SCARA5 through modifying β-catenin degradation

(2018) Hongliang Liu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Divergent lncRNA GATA3-AS1 Regulates GATA3 Transcription in T-Helper 2 Cells

(2018) Hunter R. Gibbons et al.   Frontiers in Immunology

LincRNA-Gm4419 knockdown ameliorates NF-κB/NLRP3 inflammasome-mediated inflammation in diabetic nephropathy

(2017) Hong Yi et al.   Cell Death & Disease

Long non-coding RNAs-towards precision medicine in diabetic kidney disease?

(2016) U. Panchapakesan et al.   CLINICAL SCIENCE

USP14 regulates autophagy by suppressing K63 ubiquitination of Beclin 1

(2016) Daichao Xu et al.   GENES & DEVELOPMENT

Enhanced Epithelial-to-Mesenchymal Transition Associated with Lysosome Dysfunction in Podocytes: Role of p62/Sequestosome 1 as a Signaling Hub

(2015) Guangbi Li et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

microRNA classifiers are powerful diagnostic/prognostic tools inALK-,EGFR-, andKRAS-driven lung cancers

(2015) Pierluigi Gasparini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation and activation of ubiquitin-specific protease-14 by Akt regulates the ubiquitin-proteasome system

(2015) Daichao Xu et al.   eLife

NFAT2 inhibitor ameliorates diabetic nephropathy and podocyte injury indb/dbmice

(2013) Li Zhang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Long Noncoding RNAs: Cellular Address Codes in Development and Disease

(2013) Pedro J. Batista et al.   CELL

New Therapies for Diabetic Kidney Disease

(2013) Jonathan Himmelfarb et al.   NEW ENGLAND JOURNAL OF MEDICINE

Rapamycin Upregulates Autophagy by Inhibiting the mTOR-ULK1 Pathway, Resulting in Reduced Podocyte Injury

(2013) Lingling Wu et al.   PLoS One

Role of mTOR in podocyte function and diabetic nephropathy in humans and mice

(2011) Markus Gödel et al.   JOURNAL OF CLINICAL INVESTIGATION

The Tuberin/mTOR Pathway Promotes Apoptosis of Tubular Epithelial Cells in Diabetes

(2011) C. Velagapudi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Emergence of lncRNAs in Cancer Biology

(2011) J. R. Prensner et al.   Cancer Discovery

Enhancement of proteasome activity by a small-molecule inhibitor of USP14

(2010) Byung-Hoon Lee et al.   NATURE

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE