Quercetin: A promising phytochemical for the treatment of glioblastoma multiforme

Emerging roles of microRNAs in regulating the mTOR signaling pathway during tumorigenesis

(2019) Hossein Javid et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

TGF-β/PI3K/AKT/mTOR/NF-kB pathway. Clinicopathological features in prostate cancer

(2019) Norelia Torrealba et al.   Aging Male

Evaluating the performance of MM/PBSA for binding affinity prediction using class A GPCR crystal structures

(2019) Mei Qian Yau et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Quercetin and Sodium Butyrate Synergistically Increase Apoptosis in Rat C6 and Human T98G Glioblastoma Cells Through Inhibition of Autophagy

(2019) Matthew A. Taylor et al.   NEUROCHEMICAL RESEARCH

The Anti-Cancer Effect of Quercetin: Molecular Implications in Cancer Metabolism

(2019) Marjorie Reyes-Farias et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Targeted delivery of quercetin via pH-responsive zinc oxide nanoparticles for breast cancer therapy

(2019) Pritam Sadhukhan et al.   Materials Science & Engineering C-Materials for Biological Applications

Monocarboxylate transporters in cancer

(2019) Valéry L. Payen et al.   Molecular Metabolism

Role of AKT and mTOR signaling pathways in the induction of epithelial-mesenchymal transition (EMT) process

(2019) Mostafa Karimi Roshan et al.   BIOCHIMIE

Rosmarinic acid and siRNA combined therapy represses Hsp27 (HSPB1) expression and induces apoptosis in human glioma cells

(2018) Aslıhan Şengelen et al.   CELL STRESS & CHAPERONES

Effects of quercetin combined with anticancer drugs on metastasis-associated factors of gastric cancer cells: in vitro and in vivo studies

(2018) Cing-Syuan Lei et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Quercetin suppresses the mobility of breast cancer by suppressing glycolysis through Akt-mTOR pathway mediated autophagy induction

(2018) Lijun Jia et al.   LIFE SCIENCES

Quercetin inhibits prostate cancer by attenuating cell survival and inhibiting anti-apoptotic pathways

(2018) Ashley B. Ward et al.   World Journal of Surgical Oncology

Antioxidant and anti-inflammatory activities of quercetin and its derivatives

(2018) Marija Lesjak et al.   Journal of Functional Foods

Different antitumor effects of quercetin, quercetin-3′-sulfate and quercetin-3-glucuronide in human breast cancer MCF-7 cells

(2018) Qiu Wu et al.   Food & Function

The Monocarboxylate transporter inhibitor Quercetin induces intracellular acidification in a mouse model of Glioblastoma Multiforme: in-vivo detection using magnetic resonance imaging

(2018) Mohammed Albatany et al.   INVESTIGATIONAL NEW DRUGS

Curcumin and Quercetin Synergistically Inhibit Cancer Cell Proliferation in Multiple Cancer Cells and Modulate Wnt/β-catenin Signaling and Apoptotic Pathways in A375 Cells

(2018) Nishtha S Srivastava et al.   PHYTOMEDICINE

Anticancer potential of quercetin: A comprehensive review

(2018) Abdur Rauf et al.   PHYTOTHERAPY RESEARCH

Synergistic anticancer action of quercetin and curcumin against triple-negative breast cancer cell lines

(2018) Sai Kundur et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cancer Stem Cells and Immunosuppressive Microenvironment in Glioma

(2018) Qianquan Ma et al.   Frontiers in Immunology

VEGF as a modulator of the innate immune response in glioblastoma

(2017) Kati Turkowski et al.   GLIA

Rutin increases the cytotoxicity of temozolomide in glioblastoma via autophagy inhibition

(2017) Pingde Zhang et al.   JOURNAL OF NEURO-ONCOLOGY

“Heat shock protein 70 in pancreatic diseases: Friend or foe”

(2017) Bhuwan Giri et al.   JOURNAL OF SURGICAL ONCOLOGY

Low concentration of quercetin antagonizes the invasion and angiogenesis of human glioblastoma U251 cells

(2017) Yue Liu et al.   OncoTargets and Therapy

Quercetin derivative induces cell death in glioma cells by modulating NF-κB nuclear translocation and caspase-3 activation

(2016) Cíntia J. Kiekow et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Quercetin sensitizes glioblastoma to t-AUCB by dual inhibition of Hsp27 and COX-2 in vitro and in vivo

(2016) Junyang Li et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Quercetin blocks t-AUCB-induced autophagy by Hsp27 and Atg7 inhibition in glioblastoma cells in vitro

(2016) Junyang Li et al.   JOURNAL OF NEURO-ONCOLOGY

PI-103 and Quercetin Attenuate PI3K-AKT Signaling Pathway in T- Cell Lymphoma Exposed to Hydrogen Peroxide

(2016) Akhilendra Kumar Maurya et al.   PLoS One

Molecular Targets Underlying the Anticancer Effects of Quercetin: An Update

(2016) Fazlullah Khan et al.   Nutrients

Quercetin, Inflammation and Immunity

(2016) Yao Li et al.   Nutrients

Human Phospholipase D Activity Transiently Regulates Pyrimidine Biosynthesis in Malignant Gliomas

(2015) Thomas P. Mathews et al.   ACS Chemical Biology

Autophagy contributes to the enrichment and survival of colorectal cancer stem cells under oxaliplatin treatment

(2015) Hao-Zheng Yang et al.   CANCER LETTERS

The role of heat shock proteins in cancer

(2015) Georgios D. Lianos et al.   CANCER LETTERS

Src/STAT3-dependent heme oxygenase-1 induction mediates chemoresistance of breast cancer cells to doxorubicin by promoting autophagy

(2015) Qixing Tan et al.   CANCER SCIENCE

CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2008-2012

(2015) Quinn T. Ostrom et al.   NEURO-ONCOLOGY

Quercetin promotes cell apoptosis and inhibits the expression of MMP-9 and fibronectin via the AKT and ERK signalling pathways in human glioma cells

(2015) Hong-Chao Pan et al.   NEUROCHEMISTRY INTERNATIONAL

Inhibition of autophagy induced by quercetin at a late stage enhances cytotoxic effects on glioma cells

(2015) Yunke Bi et al.   TUMOR BIOLOGY

Quercetin sensitizes human glioblastoma cells to temozolomide in vitro via inhibition of Hsp27

(2014) Dong-ping Sang et al.   ACTA PHARMACOLOGICA SINICA

Autophagy Inhibition Augments the Anticancer Effects of Epirubicin Treatment in Anthracycline-Sensitive and -Resistant Triple-Negative Breast Cancer

(2014) S. Chittaranjan et al.   CLINICAL CANCER RESEARCH

Quercetin suppresses HeLa cells by blocking PI3K/Akt pathway

(2014) Tao Xiang et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

The effect of quercetin and imperatorin on programmed cell death induction in T98G cells in vitro

(2014) Dorota Bądziul et al.   Pharmacological Reports

A novel androstenedione derivative induces ROS-mediated autophagy and attenuates drug resistance in osteosarcoma by inhibiting macrophage migration inhibitory factor (MIF)

(2014) Y Liu et al.   Cell Death & Disease

Increase in tumor-associated macrophages after antiangiogenic therapy is associated with poor survival among patients with recurrent glioblastoma

(2013) C. Lu-Emerson et al.   NEURO-ONCOLOGY

Quercetin and Sorafenib as a Novel and Effective Couple in Programmed Cell Death Induction in Human Gliomas

(2013) Joanna Jakubowicz-Gil et al.   NEUROTOXICITY RESEARCH

Quercetin Increases the Efficacy of Glioblastoma Treatment Compared to Standard Chemoradiotherapy by the Suppression of PI-3-Kinase-Akt Pathway

(2013) Eva Pozsgai et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Quercetin Induces Mitochondrial Mediated Apoptosis and Protective Autophagy in Human Glioblastoma U373MG Cells

(2013) Hyeonji Kim et al.   Oxidative Medicine and Cellular Longevity

Silencing of Hsp27 and Hsp72 in glioma cells as a tool for programmed cell death induction upon temozolomide and quercetin treatment

(2013) Joanna Jakubowicz-Gil et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Apoptosis induction in human glioblastoma multiforme T98G cells upon temozolomide and quercetin treatment

(2013) Joanna Jakubowicz-Gil et al.   TUMOR BIOLOGY

The JAK2/STAT3 and mitochondrial pathways are essential for quercetin nanoliposome-induced C6 glioma cell death

(2013) G Wang et al.   Cell Death & Disease

Quercetin abrogates IL-6/STAT3 signaling and inhibits glioblastoma cell line growth and migration

(2012) Jonathan Michaud-Levesque et al.   EXPERIMENTAL CELL RESEARCH

Life or death: Neuroprotective and anticancer effects of quercetin

(2012) Federico Dajas   JOURNAL OF ETHNOPHARMACOLOGY

Manipulation of adenovirus interactions with host factors for gene therapy applications

(2012) Margaret R Duffy et al.   Nanomedicine

PI3K-PKB/Akt Pathway

(2012) B. A. Hemmings et al.   Cold Spring Harbor Perspectives in Biology

Quercetin-induced downregulation of phospholipase D1 inhibits proliferation and invasion in U87 glioma cells

(2011) Mi Hee Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Interfering with pH regulation in tumours as a therapeutic strategy

(2011) Dario Neri et al.   NATURE REVIEWS DRUG DISCOVERY

NFκB inhibitors induce cell death in glioblastomas

(2010) Alfeu Zanotto-Filho et al.   BIOCHEMICAL PHARMACOLOGY

Temozolomide, quercetin and cell death in the MOGGCCM astrocytoma cell line

(2010) Joanna Jakubowicz-Gil et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice

(2010) Mitomu Kioi et al.   JOURNAL OF CLINICAL INVESTIGATION

Proton dynamics in cancer

(2010) Veronica Huber et al.   Journal of Translational Medicine

Resveratrol and quercetin cooperate to induce senescence-like growth arrest in C6 rat glioma cells

(2009) Lauren L. Zamin et al.   CANCER SCIENCE

Effect of quercetin on platelet spreading on collagen and fibrinogen and on multiple platelet kinases

(2009) Leyre Navarro-Núñez et al.   FITOTERAPIA

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

(2009) Roger Stupp et al.   LANCET ONCOLOGY

Quercetin promotes degradation of survivin and thereby enhances death-receptor–mediated apoptosis in glioma cells

(2008) Markus D. Siegelin et al.   NEURO-ONCOLOGY

Underlying Mechanism of Quercetin-induced Cell Death in Human Glioma Cells

(2008) Eui Joong Kim et al.   NEUROCHEMICAL RESEARCH