PI-103 and Quercetin Attenuate PI3K-AKT Signaling Pathway in T- Cell Lymphoma Exposed to Hydrogen Peroxide

Controlled release of drug and better bioavailability using poly(lactic acid-co-glycolic acid) nanoparticles

(2016) Sanjeev K. Pandey et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Reactive oxygen species in redox cancer therapy

(2015) Lingying Tong et al.   CANCER LETTERS

Quercetin: A flavonol with multifaceted therapeutic applications?

(2015) Gabriele D'Andrea   FITOTERAPIA

PI3K and AKT: Unfaithful Partners in Cancer

(2015) Seraina Faes et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Anticarcinogenic action of quercetin by downregulation of phosphatidylinositol 3-kinase (PI3K) and protein kinase C (PKC) via induction of p53 in hepatocellular carcinoma (HepG2) cell line

(2015) Akhilendra Kumar Maurya et al.   MOLECULAR BIOLOGY REPORTS

Abstract A07: Decline in the growth of murine T-cell lymphoma via modulation of PI3K signaling pathway: Key role of quercetin and PI-103

(2015) Akhilendra Kumar Maurya et al.   MOLECULAR CANCER THERAPEUTICS

Quercetin Regresses Dalton's Lymphoma Growth via Suppression of PI3K/AKT Signaling Leading to Upregulation of p53 and Decrease in Energy Metabolism

(2015) Akhilendra Kumar Maurya et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Modulation of PKC signaling and induction of apoptosis through suppression of reactive oxygen species and tumor necrosis factor receptor 1 (TNFR1): key role of quercetin in cancer prevention

(2015) Akhilendra Kumar Maurya et al.   TUMOR BIOLOGY

Rapamycin alleviates cisplatin-induced ototoxicity in vivo

(2014) Bin Fang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cancer-Associated PTEN Mutants Act in a Dominant-Negative Manner to Suppress PTEN Protein Function

(2014) Antonella Papa et al.   CELL

ROS Function in Redox Signaling and Oxidative Stress

(2014) Michael Schieber et al.   CURRENT BIOLOGY

Ellagic Acid Induces Novel and Atypical PKC Isoforms and Promotes Caspase-3 Dependent Apoptosis by Blocking Energy Metabolism

(2014) Sudha Mishra et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Long Term Effect of Curcumin in Regulation of Glycolytic Pathway and Angiogenesis via Modulation of Stress Activated Genes in Prevention of Cancer

(2014) Laxmidhar Das et al.   PLoS One

Posttranslational regulation of Akt in human cancer

(2014) Chia-Hsin Chan et al.   Cell and Bioscience

Molecular Pathways: Reactive Oxygen Species Homeostasis in Cancer Cells and Implications for Cancer Therapy

(2013) V. Nogueira et al.   CLINICAL CANCER RESEARCH

TNF-α/TNFR1 signaling promotes gastric tumorigenesis through induction of Noxo1 and Gna14 in tumor cells

(2013) H Oshima et al.   ONCOGENE

Testosterone exerts antiapoptotic effects against H2O2 in C2C12 skeletal muscle cells through the apoptotic intrinsic pathway

(2012) Lucía Pronsato et al.   JOURNAL OF ENDOCRINOLOGY

ERK1/2 MAP kinases: Structure, function, and regulation

(2012) Robert Roskoski   PHARMACOLOGICAL RESEARCH

TNFR1-induced activation of the classical NF-κB pathway

(2011) Harald Wajant et al.   FEBS Journal

Signal transduction by reactive oxygen species

(2011) Toren Finkel   JOURNAL OF CELL BIOLOGY

Intracellular reactive oxygen species are essential for PI3K/Akt/mTOR-dependent IL-7-mediated viability of T-cell acute lymphoblastic leukemia cells

(2011) A Silva et al.   LEUKEMIA

The emerging mechanisms of isoform-specific PI3K signalling

(2010) Bart Vanhaesebroeck et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hydrogen Peroxide as a Cell-Survival Signaling Molecule

(2009) Gillian Groeger et al.   ANTIOXIDANTS & REDOX SIGNALING

A Molecular Link between AKT Regulation and Chemotherapeutic Response

(2009) Christian C. Dibble et al.   CANCER CELL

PI3K Regulatory Subunits Lose Control in Cancer

(2009) Inma Martin-Berenjeno et al.   CANCER CELL

Reactive oxygen species-dependent signaling regulates cancer

(2009) Frank Weinberg et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Effect of quercetin on platelet spreading on collagen and fibrinogen and on multiple platelet kinases

(2009) Leyre Navarro-Núñez et al.   FITOTERAPIA

The tumor-promoting actions of TNF-α involve TNFR1 and IL-17 in ovarian cancer in mice and humans

(2009) Kellie A. Charles et al.   JOURNAL OF CLINICAL INVESTIGATION

Reactive Oxygen Species Mediate TNFR1 Increase after TRPV1 Activation in Mouse DRG Neurons

(2009) Fei Ma et al.   Molecular Pain

Targeting the phosphoinositide 3-kinase pathway in cancer

(2009) Pixu Liu et al.   NATURE REVIEWS DRUG DISCOVERY

Regulation of phosphoinositide 3-kinase expression in health and disease

(2009) Klaartje Kok et al.   TRENDS IN BIOCHEMICAL SCIENCES

PTEN and the PI3-Kinase Pathway in Cancer

(2008) Nader Chalhoub et al.   Annual Review of Pathology-Mechanisms of Disease

Dual Inhibition of PI3K  and mTOR as an Alternative Treatment for Kaposi's Sarcoma

(2008) R. Chaisuparat et al.   CANCER RESEARCH

Tumour cell survival signalling by the ERK1/2 pathway

(2008) K Balmanno et al.   CELL DEATH AND DIFFERENTIATION

PI-103, a dual inhibitor of Class IA phosphatidylinositide 3-kinase and mTOR, has antileukemic activity in AML

(2008) S Park et al.   LEUKEMIA

Class I PI3K in oncogenic cellular transformation

(2008) L Zhao et al.   ONCOGENE

PI3K pathway alterations in cancer: variations on a theme

(2008) T L Yuan et al.   ONCOGENE

TNFα acting on TNFR1 promotes breast cancer growth via p42/P44 MAPK, JNK, Akt and NF-κB-dependent pathways

(2007) Martín A. Rivas et al.   EXPERIMENTAL CELL RESEARCH