HIV-1 Nef counteracts autophagy restriction by enhancing the association between BECN1 and its inhibitor BCL2 in a PRKN-dependent manner

Regulation of LC3 Lipidation by the Autophagy-Specific Class III Phosphatidylinostitol-3 Kinase Complex

(2019) Livia W. Brier et al.   MOLECULAR BIOLOGY OF THE CELL

The BARA Necessities of PtdIns 3-Kinase Activation in Autophagy

(2019) Chunmei Chang et al.   Autophagy

Autophagy and Alzheimer’s Disease: From Molecular Mechanisms to Therapeutic Implications

(2018) Md. Sahab Uddin et al.   Frontiers in Aging Neuroscience

AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc– Activity

(2018) Xinxin Song et al.   CURRENT BIOLOGY

Bidirectional Control of Autophagy by BECN1 BARA Domain Dynamics

(2018) Chunmei Chang et al.   MOLECULAR CELL

Role of autophagy in HIV infection and pathogenesis

(2017) R. Nardacci et al.   JOURNAL OF INTERNAL MEDICINE

BCA2/Rabring7 Interferes with HIV-1 Proviral Transcription by Enhancing the SUMOylation of IκBα

(2017) Marta Colomer-Lluch et al.   JOURNAL OF VIROLOGY

Implication of Different HIV-1 Genes in the Modulation of Autophagy

(2017) Zhenlong Liu et al.   Viruses-Basel

Role of autophagy in cell-penetrating peptide transfection model

(2017) Moataz Dowaidar et al.   Scientific Reports

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

The Potency of Nef-Mediated SERINC5 Antagonism Correlates with the Prevalence of Primate Lentiviruses in the Wild

(2016) Anke Heigele et al.   Cell Host & Microbe

Transcriptional regulation of mammalian autophagy at a glance

(2016) Jens Füllgrabe et al.   JOURNAL OF CELL SCIENCE

TFEB at a glance

(2016) Gennaro Napolitano et al.   JOURNAL OF CELL SCIENCE

Tetherin Antagonism by HIV-1 Group M Nef Proteins

(2016) Juan F. Arias et al.   JOURNAL OF VIROLOGY

HIV-1 viral infectivity factor interacts with microtubule-associated protein light chain 3 and inhibits autophagy

(2015) Sophie Borel et al.   AIDS

Common γ-chain cytokine signaling is required for macroautophagy induction during CD4+T-cell activation

(2015) Yair Botbol et al.   Autophagy

The role for autophagy in cancer

(2015) Eileen White   JOURNAL OF CLINICAL INVESTIGATION

Autophagy in cardiovascular biology

(2015) Sergio Lavandero et al.   JOURNAL OF CLINICAL INVESTIGATION

SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef

(2015) Yoshiko Usami et al.   NATURE

HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation

(2015) Annachiara Rosa et al.   NATURE

Autophagy in Alzheimer’s disease

(2015) Ameneh Zare-shahabadi et al.   REVIEWS IN THE NEUROSCIENCES

Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A

(2015) Pui-Mun Wong et al.   Nature Communications

Human Immunodeficiency Virus Type 1 Nef Inhibits Autophagy through Transcription Factor EB Sequestration

(2015) Grant R. Campbell et al.   PLoS Pathogens

Autophagy in Mycobacterium tuberculosis and HIV infections

(2015) Lucile Espert et al.   Frontiers in Cellular and Infection Microbiology

TRIM proteins regulate autophagy: TRIM5 is a selective autophagy receptor mediating HIV-1 restriction

(2015) Michael A Mandell et al.   Autophagy

HIV-1 gp41 fusogenic function triggers autophagy in uninfected cells

(2014) Mélanie Denizot et al.   Autophagy

Viral evasion of autophagy

(2014) Anthony Orvedahl et al.   Autophagy

Regulation of ER stress-induced macroautophagy by protein kinase C

(2014) Kenjiro Sakaki et al.   Autophagy

TRIM Proteins Regulate Autophagy and Can Target Autophagic Substrates by Direct Recognition

(2014) Michael A. Mandell et al.   DEVELOPMENTAL CELL

Roles of autophagy in HIV infection

(2014) Christina Dinkins et al.   IMMUNOLOGY AND CELL BIOLOGY

Autophagy Restricts HIV-1 Infection by Selectively Degrading Tat in CD4+T Lymphocytes

(2014) Sophie Sagnier et al.   JOURNAL OF VIROLOGY

Bcl-2 Family Proteins Participate in Mitochondrial Quality Control by Regulating Parkin/PINK1-Dependent Mitophagy

(2014) Emilie Hollville et al.   MOLECULAR CELL

Parkin Sensitizes toward Apoptosis Induced by Mitochondrial Depolarization through Promoting Degradation of Mcl-1

(2014) Richard G. Carroll et al.   Cell Reports

BCA2/Rabring7 Targets HIV-1 Gag for Lysosomal Degradation in a Tetherin-Independent Manner

(2014) Ramya Nityanandam et al.   PLoS Pathogens

An Overview of Autophagy: Morphology, Mechanism, and Regulation

(2013) Katherine R. Parzych et al.   ANTIOXIDANTS & REDOX SIGNALING

Cyclic Dinucleotides Trigger ULK1 (ATG1) Phosphorylation of STING to Prevent Sustained Innate Immune Signaling

(2013) Hiroyasu Konno et al.   CELL

Inhibition of human immunodeficiency virus type-1 through autophagy

(2013) Grant R Campbell et al.   CURRENT OPINION IN MICROBIOLOGY

Identification of a candidate therapeutic autophagy-inducing peptide

(2013) Sanae Shoji-Kawata et al.   NATURE

Amino acid signalling upstream of mTOR

(2013) Jenna L. Jewell et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Tetherin/BST-2 Antagonism by Nef Depends on a Direct Physical Interaction between Nef and Tetherin, and on Clathrin-mediated Endocytosis

(2013) Ruth Serra-Moreno et al.   PLoS Pathogens

Mechanisms of Autophagosome Biogenesis

(2012) David C. Rubinsztein et al.   CURRENT BIOLOGY

Adaptation of Human and Simian Immunodeficiency Viruses for Resistance to Tetherin/BST-2

(2012) Ruth Serra-Moreno et al.   CURRENT HIV RESEARCH

Induction of Autophagy by Palmitic Acid via Protein Kinase C-mediated Signaling Pathway Independent of mTOR (Mammalian Target of Rapamycin)

(2012) Shi Hao Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HTLV-2 Tax Immortalizes Human CD4+Memory T Lymphocytes by Oncogenic Activation and Dysregulation of Autophagy

(2012) Tong Ren et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy modulation as a potential therapeutic target for diverse diseases

(2012) David C. Rubinsztein et al.   NATURE REVIEWS DRUG DISCOVERY

Structural basis of evasion of cellular adaptive immunity by HIV-1 Nef

(2012) Xiaofei Jia et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Akt-Mediated Regulation of Autophagy and Tumorigenesis Through Beclin 1 Phosphorylation

(2012) R. C. Wang et al.   SCIENCE

New insight into the oncogenic mechanism of the retroviral oncoprotein Tax

(2012) Hua Cheng et al.   Protein & Cell

Regulation of the Autophagic Bcl-2/Beclin 1 Interaction

(2012) Jean-Paul Decuypere et al.   Cells

Biogenesis and Cargo Selectivity of Autophagosomes

(2011) Hilla Weidberg et al.   Annual Review of Biochemistry

TFEB regulates autophagy: An integrated coordination of cellular degradation and recycling processes

(2011) Carmine Settembre et al.   Autophagy

The Beclin 1 network regulates autophagy and apoptosis

(2011) R Kang et al.   CELL DEATH AND DIFFERENTIATION

Compensatory Changes in the Cytoplasmic Tail of gp41 Confer Resistance to Tetherin/BST-2 in a Pathogenic Nef-Deleted SIV

(2011) Ruth Serra-Moreno et al.   Cell Host & Microbe

Tetherin Antagonism by Primate Lentiviral Nef Proteins

(2011) Daniel Sauter et al.   CURRENT HIV RESEARCH

Activation of Autophagy by α-Herpesviruses in Myeloid Cells Is Mediated by Cytoplasmic Viral DNA through a Mechanism Dependent on Stimulator of IFN Genes

(2011) Simon B. Rasmussen et al.   JOURNAL OF IMMUNOLOGY

Early Induction of Autophagy in Human Fibroblasts after Infection with Human Cytomegalovirus or Herpes Simplex Virus 1

(2011) S. McFarlane et al.   JOURNAL OF VIROLOGY

Manipulation or capitulation: virus interactions with autophagy

(2011) Tristan X. Jordan et al.   MICROBES AND INFECTION

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Canonical and non-canonical autophagy: variations on a common theme of self-eating?

(2011) Patrice Codogno et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

IRGM Is a Common Target of RNA Viruses that Subvert the Autophagy Network

(2011) Isabel Pombo Grégoire et al.   PLoS Pathogens

HIV-1 trans-activator protein dysregulates IFN-γ signaling and contributes to the suppression of autophagy induction

(2010) James CB Li et al.   AIDS

Induction of genuine autophagy by cationic lipids in mammalian cells

(2010) Na Man et al.   Autophagy

mTOR regulation of autophagy

(2010) Chang Hwa Jung et al.   FEBS LETTERS

Human Immunodeficiency Virus-1 Inhibition of Immunoamphisomes in Dendritic Cells Impairs Early Innate and Adaptive Immune Responses

(2010) Fabien P. Blanchet et al.   IMMUNITY

Parkin Mono-ubiquitinates Bcl-2 and Regulates Autophagy

(2010) Dong Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy

(2010) Sabrina Di Bartolomeo et al.   JOURNAL OF CELL BIOLOGY

Endogenous HMGB1 regulates autophagy

(2010) Daolin Tang et al.   JOURNAL OF CELL BIOLOGY

Macroautophagy Regulates Energy Metabolism during Effector T Cell Activation

(2010) V. M. Hubbard et al.   JOURNAL OF IMMUNOLOGY

Autophagy: assays and artifacts

(2010) Sandra Barth et al.   JOURNAL OF PATHOLOGY

Herpesviruses and Autophagy: Catch Me If You Can!

(2010) Yolaine Cavignac et al.   Viruses-Basel

NBR1 co-operates with p62 in selective autophagy of ubiquitinated targets

(2009) Vladimir Kirkin et al.   Autophagy

Atg14 and UVRAG: Mutually exclusive subunits of mammalian Beclin 1-PI3K complexes

(2009) Eisuke Itakura et al.   Autophagy

Nef Proteins from Simian Immunodeficiency Viruses Are Tetherin Antagonists

(2009) Fengwen Zhang et al.   Cell Host & Microbe

Tetherin-Driven Adaptation of Vpu and Nef Function and the Evolution of Pandemic and Nonpandemic HIV-1 Strains

(2009) Daniel Sauter et al.   Cell Host & Microbe

Antagonism of Beclin 1-dependent autophagy by BCL-2 at the endoplasmic reticulum requires NAF-1

(2009) Natasha C Chang et al.   EMBO JOURNAL

Loss of Parkin or PINK1 Function Increases Drp1-dependent Mitochondrial Fragmentation

(2009) A. Kathrin Lutz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages

(2009) George B. Kyei et al.   JOURNAL OF CELL BIOLOGY

Antagonism to and Intracellular Sequestration of Human Tetherin by the Human Immunodeficiency Virus Type 2 Envelope Glycoprotein

(2009) A. Le Tortorec et al.   JOURNAL OF VIROLOGY

Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

(2009) Nao Hosokawa et al.   MOLECULAR BIOLOGY OF THE CELL

ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

(2009) Chang Hwa Jung et al.   MOLECULAR BIOLOGY OF THE CELL

Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

(2009) Kohichi Matsunaga et al.   NATURE CELL BIOLOGY

Conservation of Nef function across highly diverse lineages of SIVsmm

(2009) Jan Schmökel et al.   Retrovirology

Species-Specific Activity of SIV Nef and HIV-1 Vpu in Overcoming Restriction by Tetherin/BST2

(2009) Bin Jia et al.   PLoS Pathogens

The Interferon-Induced Protein BST-2 Restricts HIV-1 Release and Is Downregulated from the Cell Surface by the Viral Vpu Protein

(2008) Nanette Van Damme et al.   Cell Host & Microbe

Role of Nef in primate lentiviral immunopathogenesis

(2008) F. Kirchhoff et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Protein Kinase Cθ Is Required for Autophagy in Response to Stress in the Endoplasmic Reticulum

(2008) Kenjiro Sakaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum

(2008) Elizabeth L. Axe et al.   JOURNAL OF CELL BIOLOGY

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

Selective Downregulation of Rhesus Macaque and Sooty Mangabey Major Histocompatibility Complex Class I Molecules by Nef Alleles of Simian Immunodeficiency Virus and Human Immunodeficiency Virus Type 2

(2008) M. Q. DeGottardi et al.   JOURNAL OF VIROLOGY

Beclin 1 Forms Two Distinct Phosphatidylinositol 3-Kinase Complexes with Mammalian Atg14 and UVRAG

(2008) Eisuke Itakura et al.   MOLECULAR BIOLOGY OF THE CELL

Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu

(2008) Stuart J. D. Neil et al.   NATURE