Ruthenium-Catalyzed Direct Asymmetric Reductive Amination of Diaryl and Sterically Hindered Ketones with Ammonium Salts and H2

Chiral Bidentate Boryl Ligand Enabled Iridium-Catalyzed Asymmetric C(sp2)–H Borylation of Diarylmethylamines

(2019) Xiaoliang Zou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Rhodium-Catalyzed Addition of Arylboroxines to N-Unprotected Ketimines: Efficient Synthesis of Cipargamin

(2019) Jinbin Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reductive Amination in the Synthesis of Pharmaceuticals

(2019) Oleg I. Afanasyev et al.   CHEMICAL REVIEWS

2-Hydroxybenzophenone as a Chemical Auxiliary for the Activation of Ketiminoesters for Highly Enantioselective Addition to Nitroalkenes under Bifunctional Catalysis

(2018) Andrea Guerrero-Corella et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Enantioselective Synthesis of Chiral Diarylmethylamines from Racemic Alcohols

(2018) Min Chen et al.   CHINESE JOURNAL OF CHEMISTRY

Asymmetric Synthesis of Chiral Primary Amines by Ruthenium-Catalyzed Direct Reductive Amination of Alkyl Aryl Ketones with Ammonium Salts and Molecular H2

(2018) Xuefeng Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dynamic Kinetic Asymmetric Reductive Amination: Synthesis of Chiral Primary β-amino Lactams

(2018) Yazhou Lou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pd(ii), Ni(ii) and Co(ii)-catalyzed enantioselective additions of organoboron reagents to ketimines

(2018) Mao Quan et al.   CHEMICAL COMMUNICATIONS

Asymmetric Stepwise Reductive Amination of Sulfonamides, Sulfamates, and a Phosphinamide by Nickel Catalysis

(2018) Xiaohu Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hydrogen-Bonding-Assisted Ketimine Formation of Benzophenone Derivatives

(2018) Min-Seob Seo et al.   JOURNAL OF ORGANIC CHEMISTRY

Pd(OAc)2-catalyzed asymmetric hydrogenation of sterically hindered N-tosylimines

(2018) Jianzhong Chen et al.   Nature Communications

Direct Asymmetric Ruthenium-Catalyzed Reductive Amination of Alkyl–Aryl Ketones with Ammonia and Hydrogen

(2017) Joan Gallardo-Donaire et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Asymmetric Reductive Amination for the Synthesis of Chiral β-Arylamines

(2016) Haizhou Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Synthesis of Isoquinoline Alkaloids: 2004–2015

(2016) Maria Chrzanowska et al.   CHEMICAL REVIEWS

Enantioselective Hydrogenation of Diarylmethanimines for Synthesis of Chiral Diarylmethylamines

(2016) Duanyang Kong et al.   JOURNAL OF ORGANIC CHEMISTRY

Discovery and Structure-Guided Optimization of Diarylmethanesulfonamide Disrupters of Glucokinase–Glucokinase Regulatory Protein (GK–GKRP) Binding: Strategic Use of a N → S (nN → σ*S–X) Interaction for Conformational Constraint

(2015) Lewis D. Pennington et al.   JOURNAL OF MEDICINAL CHEMISTRY

Palladium-Catalyzed Enantioselective Three-Component Synthesis of α-Substituted Amines

(2015) Tamara Beisel et al.   ORGANIC LETTERS

Synthesis of Chiral Trifluoromethyl-Substituted Hydrazines via Pd-Catalyzed Asymmetric Hydrogenation and Reductive Amination

(2015) Zhang-Pei Chen et al.   ACS Catalysis

Cooperative Catalysis with Iron and a Chiral Brønsted Acid for Asymmetric Reductive Amination of Ketones

(2014) Shaolin Zhou et al.   ADVANCED SYNTHESIS & CATALYSIS

A New Type of Chiral Sulfinamide Monophosphine Ligands: Stereodivergent Synthesis and Application in Enantioselective Gold(I)-Catalyzed Cycloaddition Reactions

(2014) Zhan-Ming Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pd-Catalyzed Enantioselective C–H Iodination: Asymmetric Synthesis of Chiral Diarylmethylamines

(2013) Ling Chu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diaminophosphine Oxide Ligand Enabled Asymmetric Nickel-Catalyzed Hydrocarbamoylations of Alkenes

(2013) Pavel A. Donets et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Update 1 of:C2-Symmetric Chiral Bis(oxazoline) Ligands in Asymmetric Catalysis

(2011) Giovanni Desimoni et al.   CHEMICAL REVIEWS

Chiral Phosphoric Acid Catalyzed Enantioselective Transfer Hydrogenation of ortho-Hydroxybenzophenone NH Ketimines and Applications

(2011) Thanh Binh Nguyen et al.   CHEMISTRY-A EUROPEAN JOURNAL

Asymmetric Synthesis of 1,3-Diamines. II: Diastereoselective Reduction of AtropisomericN-tert-Butanesulfinylketimines

(2011) Marina Martjuga et al.   JOURNAL OF ORGANIC CHEMISTRY

Reaction Development and Mechanistic Study of a Ruthenium Catalyzed Intramolecular Asymmetric Reductive Amination en Route to the Dual Orexin Inhibitor Suvorexant (MK-4305)

(2011) Neil A. Strotman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Synthesis of (S)-3-Amino-4-methoxy-butan-1-ol by Way of Reductive Amination

(2011) Patrizio Mattei et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Chiral Amine Synthesis - Recent Developments and Trends for Enamide Reduction, Reductive Amination, and Imine Reduction

(2010) Thomas C. Nugent et al.   ADVANCED SYNTHESIS & CATALYSIS

Transition Metal-Catalyzed Enantioselective Hydrogenation of Enamines and Imines

(2010) Jian-Hua Xie et al.   CHEMICAL REVIEWS

New Chiral N-Heterocyclic Carbene Ligands in Palladium-Catalyzed α-Arylations of Amides: Conformational Locking through Allylic Strain as a Device for Stereocontrol

(2010) Yi-Xia Jia et al.   CHEMISTRY-A EUROPEAN JOURNAL

Iridium−Monodentate Phosphoramidite-Catalyzed Asymmetric Hydrogenation of Substituted Benzophenone N−H Imines

(2010) Guohua Hou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral Phosphoric Acid-Catalyzed Enantioselective Transfer Hydrogenation ofortho-Hydroxyaryl Alkyl N−H Ketimines

(2010) Thanh Binh Nguyen et al.   ORGANIC LETTERS

Enantioselective Hydrogenation of N−H Imines

(2009) Guohua Hou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Asymmetric Reductive Amination

(2009) Dietrich Steinhuebel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Metal−Brønsted Acid Cooperative Catalysis for Asymmetric Reductive Amination

(2009) Chaoqun Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A simple and convenient synthesis of 4-methyl-3-nitro-2-trihalomethyl-2H-chromenes from N-unsubstituted imines of 2-hydroxyacetophenones and trichloro(trifluoro)ethylidene nitromethanes

(2008) Vladislav Yu. Korotaev et al.   TETRAHEDRON