Gold and Carbene Relay Catalytic Enantioselective Cycloisomerization/Cyclization Reactions of Ynamides and Enals

N-Heterocyclic Carbene/Copper Cooperative Catalysis for the Asymmetric Synthesis of Spirooxindoles

(2019) Zi-Jing Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synergistic N-Heterocyclic Carbene/Palladium-Catalyzed Reactions of Aldehyde Acyl Anions with either Diarylmethyl or Allylic Carbonates

(2018) Shigeo Yasuda et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Conjugated Dienyne-Imides as Robust Precursors of 1-Azatrienes for 6π Electrocyclizations to Furo[2,3-b ]dihydropyridine Cores

(2018) Yanjun Wan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Heterocyclic Carbene Catalysis via Azolium Dienolates: An Efficient Strategy for Remote Enantioselective Functionalizations

(2018) Xiang-Yu Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A continuing challenge: N-heterocyclic carbene-catalyzed syntheses of γ-butyrolactones

(2018) Kathleen J. R. Murauski et al.   CHEMICAL SOCIETY REVIEWS

Highly Enantioselective [5 + 2] Annulations through Cooperative N-Heterocyclic Carbene (NHC) Organocatalysis and Palladium Catalysis

(2018) Santanu Singha et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Cα-Alkylation of Proline via Chirality Transfers of Conformationally Restricted Proline Derivative: Application to the Total Synthesis of (−)-Amathaspiramide F

(2018) Hyunkyung Cho et al.   ORGANIC LETTERS

Access to All-Carbon Spirocycles through a Carbene and Thiourea Cocatalytic Desymmetrization Cascade Reaction

(2018) Shitian Zhuo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Sulfinate and Carbene Co-catalyzed Rauhut-Currier Reaction for Enantioselective Access to Azepino[1,2-a ]indoles

(2018) Xingxing Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dehydrative Allylation between Aldehydes and Allylic Alcohols through Synergistic N-Heterocyclic Carbene/Palladium Catalysis

(2018) Hiroki Haruki et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective β-Protonation of Enals via a Shuttling Strategy

(2017) Jiean Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanistic Studies on a Cooperative NHC Organocatalysis/Palladium Catalysis System: Uncovering Significant Lessons for Mixed Chiral Pd(NHC)(PR3) Catalyst Design

(2017) Chang Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Parameterization of Acyclic Diaminocarbene Ligands Applied to a Gold(I)-Catalyzed Enantioselective Tandem Rearrangement/Cyclization

(2017) Zachary L. Niemeyer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Improving Metabolic Stability with Deuterium: The Discovery of BMT-052, a Pan-genotypic HCV NS5B Polymerase Inhibitor

(2017) Kyle Parcella et al.   ACS Medicinal Chemistry Letters

N-Heterocyclic Carbene Catalysis via the α,β-Unsaturated Acyl Azolium

(2017) Changhe Zhang et al.   ACS Catalysis

Enantioselective, Stereodivergent Hydroazidation and Hydroamination of Allenes Catalyzed by Acyclic Diaminocarbene (ADC) Gold(I) Complexes

(2016) Dimitri A. Khrakovsky et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cooperative Catalysis and Activation with N-Heterocyclic Carbenes

(2016) Michael H. Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Combinations of Aminocatalysts and Metal Catalysts: A Powerful Cooperative Approach in Selective Organic Synthesis

(2016) Samson Afewerki et al.   CHEMICAL REVIEWS

Recent advances in enantioselective gold catalysis

(2016) Weiwei Zi et al.   CHEMICAL SOCIETY REVIEWS

Palladium/l-Proline-Catalyzed Enantioselective α-Arylative Desymmetrization of Cyclohexanones

(2016) Ren-Rong Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cooperative N-Heterocyclic Carbene/Palladium-Catalyzed Enantioselective Umpolung Annulations

(2016) Chang Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral Primary Amine/Palladium Dual Catalysis for Asymmetric Allylic Alkylation of β-Ketocarbonyl Compounds with Allylic Alcohols

(2015) Han Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric γ-Allylation of α,β-Unsaturated Aldehydes by Combined Organocatalysis and Transition-Metal Catalysis

(2015) Line Naesborg et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Reactions Enabled by N-Heterocyclic Carbenes

(2015) Darrin M. Flanigan et al.   CHEMICAL REVIEWS

Gold-catalyzed cyclopropanation reactions using a carbenoid precursor toolbox

(2015) Deyun Qian et al.   CHEMICAL SOCIETY REVIEWS

Recent advances in employing homoenolates generated by N-heterocyclic carbene (NHC) catalysis in carbon–carbon bond-forming reactions

(2015) Rajeev S. Menon et al.   CHEMICAL SOCIETY REVIEWS

Switchable selectivity in an NHC-catalysed dearomatizing annulation reaction

(2015) Chang Guo et al.   Nature Chemistry

On the Mechanism of N-Heterocyclic Carbene-Catalyzed Reactions Involving Acyl Azoliums

(2014) Jessada Mahatthananchai et al.   ACCOUNTS OF CHEMICAL RESEARCH

A Non-Diazo Approach to α-Oxo Gold Carbenes via Gold-Catalyzed Alkyne Oxidation

(2014) Liming Zhang   ACCOUNTS OF CHEMICAL RESEARCH

Dual Gold Catalysis

(2014) A. Stephen K. Hashmi   ACCOUNTS OF CHEMICAL RESEARCH

Asymmetric Organocatalysis Combined with Metal Catalysis: Concept, Proof of Concept, and Beyond

(2014) Dian-Feng Chen et al.   ACCOUNTS OF CHEMICAL RESEARCH

Dual-function Pd/NHC catalysis: tandem allylation–isomerization–conjugate addition that allows access to pyrroles, thiophenes and furans

(2014) Yaguang Bai et al.   CHEMICAL COMMUNICATIONS

Stereodivergent α-Allylation of Linear Aldehydes with Dual Iridium and Amine Catalysis

(2014) Simon Krautwald et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An overview of N-heterocyclic carbenes

(2014) Matthew N. Hopkinson et al.   NATURE

Pd-Catalyzed Branching Cyclizations of Enediyne-Imides toward Furo[2,3-b]pyridines

(2014) Zexiang Li et al.   ORGANIC LETTERS

A cooperative N-heterocyclic carbene/palladium catalysis system

(2014) Kun Liu et al.   Chemical Science

Metal and carbene organocatalytic relay activation of alkynes for stereoselective reactions

(2014) Kayambu Namitharan et al.   Nature Communications

Gold-Catalyzed Rearrangements and Beyond

(2013) Carla Obradors et al.   ACCOUNTS OF CHEMICAL RESEARCH

Development of Catalysts and Ligands for Enantioselective Gold Catalysis

(2013) Yi-Ming Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Highly Active Mononuclear NAC-Gold(I) Catalysts

(2013) Maria Camila Blanco Jaimes et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

exo-Selective construction of spiro-[butyrolactone-pyrrolidine] via 1,3-dipolar cycloaddition of azomethine ylides with α-methylene-γ-butyrolactone catalyzed by Cu(i)/DTBM-BIPHEP

(2013) Qing-Hua Li et al.   CHEMICAL COMMUNICATIONS

Acyl anion free N-heterocyclic carbene organocatalysis

(2013) Sarah J. Ryan et al.   CHEMICAL SOCIETY REVIEWS

Carbene Transfer from Triazolylidene Gold Complexes as a Potent Strategy for Inducing High Catalytic Activity

(2013) Daniel Canseco-Gonzalez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantio- and Diastereodivergent Dual Catalysis:  -Allylation of Branched Aldehydes

(2013) S. Krautwald et al.   SCIENCE

Enantioselective Alkynylbenzaldehyde Cyclizations Catalyzed by Chiral Gold(I) Acyclic Diaminocarbene Complexes Containing Weak Au-Arene Interactions

(2012) Sachin Handa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent advances in the isolation and reactivity of organogold complexes

(2012) Le-Ping Liu et al.   CHEMICAL SOCIETY REVIEWS

Combining transition metal catalysis and organocatalysis – an update

(2012) Zhenting Du et al.   CHEMICAL SOCIETY REVIEWS

Pd(II)/Brønsted Acid Catalyzed Enantioselective Allylic C–H Activation for the Synthesis of Spirocyclic Rings

(2012) Zhuo Chai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Oxidative γ-Addition of Enals to Trifluoromethyl Ketones: Enantioselectivity Control via Lewis Acid/N-Heterocyclic Carbene Cooperative Catalysis

(2012) Junming Mo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Axially Chiral Triazoloisoquinolin-3-ylidene Ligands in Gold(I)-Catalyzed Asymmetric Intermolecular (4 + 2) Cycloadditions of Allenamides and Dienes

(2012) Javier Francos et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synergistic catalysis: A powerful synthetic strategy for new reaction development

(2012) Anna E. Allen et al.   Chemical Science

Gold-Catalyzed Carbon−Heteroatom Bond-Forming Reactions

(2011) A. Corma et al.   CHEMICAL REVIEWS

N-Heterocyclic carbene (NHC) ligands and palladium in homogeneous cross-coupling catalysis: a perfect union

(2011) George C. Fortman et al.   CHEMICAL SOCIETY REVIEWS

Gold catalysis in total synthesis—an update

(2011) Matthias Rudolph et al.   CHEMICAL SOCIETY REVIEWS

N-Heterocyclic Carbene and Brønsted Acid Cooperative Catalysis: Asymmetric Synthesis oftrans-γ-Lactams

(2011) Xiaodan Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral (Acyclic Diaminocarbene)Gold(I)-Catalyzed Dynamic Kinetic Asymmetric Transformation of Propargyl Esters

(2011) Yi-Ming Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Two tandem sequential reactions catalyzed by [Au], N-heterocyclic carbenes (NHC) and organic bases

(2011) Mauro F.A. Adamo et al.   TETRAHEDRON

Cooperative Lewis acid/N-heterocyclic carbene catalysis

(2011) Daniel T. Cohen et al.   Chemical Science

The Development and Catalytic Uses of N-Heterocyclic Carbene Gold Complexes

(2010) Steven P. Nolan   ACCOUNTS OF CHEMICAL RESEARCH

Diastereo- and Enantioselective Gold(I)-Catalyzed Intermolecular Tandem Cyclization/[3+3]Cycloadditions of 2-(1-Alkynyl)-2-alken-1-ones with Nitrones

(2010) Feng Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Furo[2,3-b]pyridine-based cannabinoid-1 receptor inverse agonists: Synthesis and biological evaluation. Part 1

(2010) John S. Debenham et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Silver triflate and N-heterocyclic carbene co-catalyzed reaction of N′-(2-alkynylbenzylidene)hydrazide, methanol with α,β-unsaturated aldehyde

(2010) Zhiyuan Chen et al.   CHEMICAL COMMUNICATIONS

Gold-catalyzed decorations of arenes and heteroarenes with C–C multiple bonds

(2010) Marco Bandini   CHEMICAL SOCIETY REVIEWS

Gold Catalysis: Tandem Reactions of Diyne-Diols and External Nucleophiles as an Easy Access to Tricyclic Cage-Like Structures

(2010) A. Stephen K. Hashmi et al.   CHEMISTRY-A EUROPEAN JOURNAL

When Organocatalysis Meets Transition-Metal Catalysis

(2010) Cheng Zhong et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis and Catalytic Activity of Gold Chiral Nitrogen Acyclic Carbenes and Gold Hydrogen Bonded Heterocyclic Carbenes in Cyclopropanation of Vinyl Arenes and in Intramolecular Hydroalkoxylation of Allenes

(2010) Camino Bartolomé et al.   INORGANIC CHEMISTRY

Cooperative catalysis by carbenes and Lewis acids in a highly stereoselective route to γ-lactams

(2010) Dustin E. A. Raup et al.   Nature Chemistry

Asymmetric Construction of Polycyclic Indoles through Olefin Cross-Metathesis/Intramolecular Friedel-Crafts Alkylation under Sequential Catalysis

(2009) Quan Cai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Discovery and SAR of novel mGluR5 non-competitive antagonists not based on an MPEP chemotype

(2009) Alice L. Rodriguez et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

N-Heterocyclic Carbenes in Late Transition Metal Catalysis

(2009) Silvia Díez-González et al.   CHEMICAL REVIEWS

Combining transition metal catalysis and organocatalysis: a broad new concept for catalysis

(2009) Zhihui Shao et al.   CHEMICAL SOCIETY REVIEWS

Consecutive Intramolecular Hydroamination/Asymmetric Transfer Hydrogenation under Relay Catalysis of an Achiral Gold Complex/Chiral Brønsted Acid Binary System

(2009) Zhi-Yong Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cooperative Catalysis with Chiral Brønsted Acid-Rh2(OAc)4: Highly Enantioselective Three-Component Reactions of Diazo Compounds with Alcohols and Imines

(2008) Wenhao Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Merging Photoredox Catalysis with Organocatalysis: The Direct Asymmetric Alkylation of Aldehydes

(2008) D. A. Nicewicz et al.   SCIENCE