N-Heterocyclic Carbene/Copper Cooperative Catalysis for the Asymmetric Synthesis of Spirooxindoles

Copper-Catalyzed Enantioselective Construction of Tertiary Propargylic Sulfones

(2019) José Enrique Gómez et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synergistic N-Heterocyclic Carbene/Palladium-Catalyzed Allylation of Aldehydes with Allylic Carbonates

(2019) Shunsuke Takemoto et al.   BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN

N-Heterocyclic Carbene Catalyzed Asymmetric Synthesis of Pentacyclic Spirooxindoles via [3+3] Annulations of Isatin-Derived Enals and Cyclic N-Sulfonyl Ketimines

(2019) Qiang Liu et al.   ADVANCED SYNTHESIS & CATALYSIS

Enantioselective [4 + 2]-Annulation of Azlactones with Copper-Allenylidenes under Cooperative Catalysis: Synthesis of α-Quaternary α-Acylaminoamides

(2019) Amit Kumar Simlandy et al.   ORGANIC LETTERS

Development of Synthetic Methodologies via Catalytic Enantioselective Synthesis of 3,3-Disubstituted Oxindoles

(2018) Zhong-Yan Cao et al.   ACCOUNTS OF CHEMICAL RESEARCH

Transition-Metal-Free Decarboxylative Propargylic Substitution/Cyclization with either Azolium Enolates or Acyl Anions

(2018) Shenci Lu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synergistic N-Heterocyclic Carbene/Palladium-Catalyzed Reactions of Aldehyde Acyl Anions with either Diarylmethyl or Allylic Carbonates

(2018) Shigeo Yasuda et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aerobic Oxidation/Annulation Cascades via Synergistic Catalysis of RuCl3 and N-Heterocyclic Carbenes

(2018) Qian Wang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Highly Enantioselective [5 + 2] Annulations through Cooperative N-Heterocyclic Carbene (NHC) Organocatalysis and Palladium Catalysis

(2018) Santanu Singha et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Lewis Base/Copper Cooperatively Catalyzed Asymmetric α-Amination of Esters with Diaziridinone

(2018) Jin Song et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Synthesis of Spiro-oxindole-ε-lactones through N-Heterocyclic Carbene Catalysis

(2018) Qiang Liu et al.   ORGANIC LETTERS

Enantioselective Decarboxylative Propargylation/Hydroamination Enabled by Organo/Metal Cooperative Catalysis

(2018) Yu-Chen Zhang et al.   ORGANIC LETTERS

Asymmetric Catalytic [4 + 2] Cycloaddition via Cu–Allenylidene Intermediate: Stereoselective Synthesis of Tetrahydroquinolines Fused with a γ-Lactone Moiety

(2018) Hao Chen et al.   ORGANIC LETTERS

Asymmetric [4 + 2]-Cycloaddition of Copper–Allenylidenes with Hexahydro-1,3,5-triazines: Access to Chiral Tetrahydroquinazolines

(2018) Danqing Ji et al.   ORGANIC LETTERS

Transition-metal-catalyzed cyclization reactions using vinyl and ethynyl benzoxazinones as dipole precursors

(2018) Tian-Ren Li et al.   TETRAHEDRON LETTERS

A C1-symmetric N-heterocyclic carbene catalysed oxidative spiroannulation of isatin-derived enals: highly enantioselective synthesis of spirooxindole δ-lactones

(2018) Jun-Bing Lin et al.   RSC Advances

NHC-Catalyzed Enantioselective [4+3] Cycloaddition of Ortho -Hydroxyphenyl Substituted Para -Quinone Methides with Isatin-Derived Enals

(2018) Wenjun Li et al.   ADVANCED SYNTHESIS & CATALYSIS

Copper-Catalyzed Enantioselective Synthesis of β-Amino Alcohols Featuring Tetrasubstituted Tertiary Carbons

(2018) Lan Tian et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric [3 + 3] Annulation of Copper–Allenylidenes with Pyrazolones: Synthesis of Chiral 1,4-Dihydropyrano[2,3-c]pyrazoles

(2018) Feng Jiang et al.   ORGANIC LETTERS

Scope and advances in the catalytic propargylic substitution reaction

(2018) Rashmi Roy et al.   RSC Advances

Dehydrative Allylation between Aldehydes and Allylic Alcohols through Synergistic N-Heterocyclic Carbene/Palladium Catalysis

(2018) Hiroki Haruki et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective N-Heterocyclic Carbene-Catalyzed Synthesis of Spirocyclic Oxindole-benzofuroazepinones

(2018) Zhong-Hua Gao et al.   JOURNAL OF ORGANIC CHEMISTRY

Catalytic Asymmetric [4 + 3] Annulation of C,N-Cyclic Azomethine Imines with Copper Allenylidenes

(2018) Yanfang Wang et al.   ORGANIC LETTERS

Enantioselective [3 + 2] Cycloaddition Reaction of Ethynylethylene Carbonates with Malononitrile Enabled by Organo/Metal Cooperative Catalysis

(2018) Yu-Chen Zhang et al.   ORGANIC LETTERS

Enantioselective β-Protonation of Enals via a Shuttling Strategy

(2017) Jiean Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanistic Studies on a Cooperative NHC Organocatalysis/Palladium Catalysis System: Uncovering Significant Lessons for Mixed Chiral Pd(NHC)(PR3) Catalyst Design

(2017) Chang Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Spirooxindoles as Potential Pharmacophores

(2017) Siva S. Panda et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Asymmetric Synthesis of Spirobenzazepinones with Atroposelectivity and Spiro-1,2-Diazepinones by NHC-Catalyzed [3+4] Annulation Reactions

(2016) Lei Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cooperative Catalysis and Activation with N-Heterocyclic Carbenes

(2016) Michael H. Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Combinations of Aminocatalysts and Metal Catalysts: A Powerful Cooperative Approach in Selective Organic Synthesis

(2016) Samson Afewerki et al.   CHEMICAL REVIEWS

Cooperative N-Heterocyclic Carbene/Palladium-Catalyzed Enantioselective Umpolung Annulations

(2016) Chang Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric [4 + 1] Annulation of Sulfur Ylides with Copper–Allenylidene Intermediates

(2016) Qiang Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Therapeutic Potential of Spirooxindoles as Antiviral Agents

(2016) Na Ye et al.   ACS Infectious Diseases

Organocatalytic Reactions Enabled by N-Heterocyclic Carbenes

(2015) Darrin M. Flanigan et al.   CHEMICAL REVIEWS

Recent advances in employing homoenolates generated by N-heterocyclic carbene (NHC) catalysis in carbon–carbon bond-forming reactions

(2015) Rajeev S. Menon et al.   CHEMICAL SOCIETY REVIEWS

Spirooxindoles: Promising scaffolds for anticancer agents

(2015) Bin Yu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Rapid Access to Spirocylic Oxindoles: Application of Asymmetric N-Heterocyclic Carbene-Catalyzed [3 + 3] Cycloaddition of Imines to Oxindole-Derived Enals

(2015) Danbo Xie et al.   ORGANIC LETTERS

Recent advances in copper-catalyzed propargylic substitution

(2015) De-Yang Zhang et al.   TETRAHEDRON LETTERS

Asymmetric Organocatalysis Combined with Metal Catalysis: Concept, Proof of Concept, and Beyond

(2014) Dian-Feng Chen et al.   ACCOUNTS OF CHEMICAL RESEARCH

The use of spirocyclic scaffolds in drug discovery

(2014) Yajun Zheng et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Dual-function Pd/NHC catalysis: tandem allylation–isomerization–conjugate addition that allows access to pyrroles, thiophenes and furans

(2014) Yaguang Bai et al.   CHEMICAL COMMUNICATIONS

A highly efficient dual catalysis approach for C-glycosylation: addition of (o-azaaryl)carboxaldehyde to glycals

(2014) Yaguang Bai et al.   CHEMICAL COMMUNICATIONS

An overview of N-heterocyclic carbenes

(2014) Matthew N. Hopkinson et al.   NATURE

A cooperative N-heterocyclic carbene/palladium catalysis system

(2014) Kun Liu et al.   Chemical Science

Metal and carbene organocatalytic relay activation of alkynes for stereoselective reactions

(2014) Kayambu Namitharan et al.   Nature Communications

Organocatalytic Asymmetric Assembly Reactions: Synthesis of Spirooxindoles via Organocascade Strategies

(2014) Daojuan Cheng et al.   ACS Catalysis

Cooperative N-Heterocyclic Carbene (NHC) and Ruthenium Redox Catalysis: Oxidative Esterification of Aldehydes with Air as the Terminal Oxidant

(2013) Junfeng Zhao et al.   ADVANCED SYNTHESIS & CATALYSIS

Combining transition metal catalysis and organocatalysis – an update

(2012) Zhenting Du et al.   CHEMICAL SOCIETY REVIEWS

Catalytic Asymmetric α-Acylation of Tertiary Amines Mediated by a Dual Catalysis Mode: N-Heterocyclic Carbene and Photoredox Catalysis

(2012) Daniel A. DiRocco et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Transition-Metal-Catalyzed Enantioselective Propargylic Substitution Reactions of Propargylic Alcohol Derivatives with Nucleophiles

(2012) Yoshiaki Nishibayashi   SYNTHESIS-STUTTGART

Transition-Metal-Catalyzed Functionalization of Propargylic Alcohols and Their Derivatives

(2012) Eike Bauer   SYNTHESIS-STUTTGART

Synergistic catalysis: A powerful synthetic strategy for new reaction development

(2012) Anna E. Allen et al.   Chemical Science

N-Heterocyclic Carbene Catalyzed Domino Reactions

(2011) André Grossmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Propargylation

(2011) Chang-Hua Ding et al.   CHEMICAL REVIEWS

Employing homoenolates generated by NHC catalysis in carbon–carbon bond-forming reactions: state of the art

(2011) Vijay Nair et al.   CHEMICAL SOCIETY REVIEWS

N-Heterocyclic Carbenes in Late Transition Metal Catalysis

(2009) Silvia Díez-González et al.   CHEMICAL REVIEWS

Asymmetric Syntheses of Oxindole and Indole Spirocyclic Alkaloid Natural Products

(2009) Barry Trost et al.   SYNTHESIS-STUTTGART

Palladium-Catalyzed C-Allylation of Benzoins and an NHC-Catalyzed Three Component Coupling Derived Thereof: Compatibility of NHC- and Pd-Catalysts

(2008) Raphaël Lebeuf et al.   ORGANIC LETTERS

Assembly of functionalized α-hydroxy carbonyl compounds via combination of N-heterocyclic carbene and Pd catalysts

(2008) Jinmei He et al.   TETRAHEDRON LETTERS