The common stress responsive transcription factor ATF3 binds genomic sites enriched with p300 and H3K27ac for transcriptional regulation

Internal Ribosome Entry Site-Based Bicistronic In Situ Reporter Assays for Discovery of Transcription-Targeted Lead Compounds

(2015) Liwei Lang et al.   CHEMISTRY & BIOLOGY

Transcription factor p63 bookmarks and regulates dynamic enhancers during epidermal differentiation

(2015) E. N. Kouwenhoven et al.   EMBO REPORTS

Integrative genomic analysis reveals widespread enhancer regulation by p53 in response to DNA damage

(2015) Scott T. Younger et al.   NUCLEIC ACIDS RESEARCH

The stress-responsive gene ATF3 regulates the histone acetyltransferase Tip60

(2015) Hongmei Cui et al.   Nature Communications

Looping Back to Leap Forward: Transcription Enters a New Era

(2014) Michael Levine et al.   CELL

The Activating Transcription Factor 3 Protein Suppresses the Oncogenic Function of Mutant p53 Proteins

(2014) Saisai Wei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-wide analysis of noncoding regulatory mutations in cancer

(2014) Nils Weinhold et al.   NATURE GENETICS

Loss of ATF3 promotes Akt activation and prostate cancer development in a Pten knockout mouse model

(2014) Z Wang et al.   ONCOGENE

DNA double-strand breaks promote methylation of histone H3 on lysine 9 and transient formation of repressive chromatin

(2014) M. K. Ayrapetov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATF3 Suppresses Metastasis of Bladder Cancer by Regulating Gelsolin-Mediated Remodeling of the Actin Cytoskeleton

(2013) X. Yuan et al.   CANCER RESEARCH

Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses

(2013) D. Kenzelmann Broz et al.   GENES & DEVELOPMENT

Transcription factor ATF3 links host adaptive response to breast cancer metastasis

(2013) Chris C. Wolford et al.   JOURNAL OF CLINICAL INVESTIGATION

The MLL3/MLL4 Branches of the COMPASS Family Function as Major Histone H3K4 Monomethylases at Enhancers

(2013) D. Hu et al.   MOLECULAR AND CELLULAR BIOLOGY

Modification of Enhancer Chromatin: What, How, and Why?

(2013) Eliezer Calo et al.   MOLECULAR CELL

Enhancers: five essential questions

(2013) Len A. Pennacchio et al.   NATURE REVIEWS GENETICS

Diverse stresses dramatically alter genome-wide p53 binding and transactivation landscape in human cancer cells

(2013) Daniel Menendez et al.   NUCLEIC ACIDS RESEARCH

Distinct p53 genomic binding patterns in normal and cancer-derived human cells

(2012) Krassimira Botcheva et al.   CELL CYCLE

ATF3 protects against atherosclerosis by suppressing 25-hydroxycholesterol–induced lipid body formation

(2012) Elizabeth S. Gold et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Stress Response Mediator ATF3 Represses Androgen Signaling by Binding the Androgen Receptor

(2012) H. Wang et al.   MOLECULAR AND CELLULAR BIOLOGY

A High-Throughput Chromatin Immunoprecipitation Approach Reveals Principles of Dynamic Gene Regulation in Mammals

(2012) Manuel Garber et al.   MOLECULAR CELL

Cell type-specific binding patterns reveal that TCF7L2 can be tethered to the genome by association with GATA3

(2012) Seth Frietze et al.   GENOME BIOLOGY

Pioneer transcription factors: establishing competence for gene expression

(2011) K. S. Zaret et al.   GENES & DEVELOPMENT

More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance

(2011) Jiri Lukas et al.   NATURE CELL BIOLOGY

ROS-induced ATF3 causes susceptibility to secondary infections during sepsis-associated immunosuppression

(2011) Wolfram Hoetzenecker et al.   NATURE MEDICINE

Systems Analysis of ATF3 in Stress Response and Cancer Reveals Opposing Effects on Pro-Apoptotic Genes in p53 Pathway

(2011) Yujiro Tanaka et al.   PLoS One

Activating Transcription Factor 3 Deficiency Promotes Cardiac Hypertrophy, Dysfunction, and Fibrosis Induced by Pressure Overload

(2011) Heng Zhou et al.   PLoS One

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Activating transcription factor-3 (ATF3) functions as a tumor suppressor in colon cancer and is up-regulated upon heat-shock protein 90 (Hsp90) inhibition

(2010) Christina Hackl et al.   BMC CANCER

An Integrated Network of Androgen Receptor, Polycomb, and TMPRSS2-ERG Gene Fusions in Prostate Cancer Progression

(2010) Jindan Yu et al.   CANCER CELL

MDM2 Mediates Ubiquitination and Degradation of Activating Transcription Factor 3

(2010) Pingli Mo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Opposing roles for calcineurin and ATF3 in squamous skin cancer

(2010) Xunwei Wu et al.   NATURE

A unique chromatin signature uncovers early developmental enhancers in humans

(2010) Alvaro Rada-Iglesias et al.   NATURE

Histone H3K27ac separates active from poised enhancers and predicts developmental state

(2010) M. P. Creyghton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

ChIP-seq accurately predicts tissue-specific activity of enhancers

(2009) Axel Visel et al.   NATURE

Activating transcription factor 3: a hormone responsive gene in the etiology of hypospadias

(2008) Ana Beleza-Meireles et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Neuronal Injury-inducible Gene Is Synergistically Regulated by ATF3, c-Jun, and STAT3 through the Interaction with Sp1 in Damaged Neurons

(2008) Sumiko Kiryu-Seo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epitope tagging of endogenous genes in diverse human cell lines

(2008) J.-S. Kim et al.   NUCLEIC ACIDS RESEARCH