The Activating Transcription Factor 3 Protein Suppresses the Oncogenic Function of Mutant p53 Proteins

Mutant p53 uses p63 as a molecular chaperone to alter gene expression and induce a pro-invasive secretome

(2015) Paul M. Neilsen et al.   Oncotarget

In Vivo RNAi Screen for BMI1 Targets Identifies TGF-β/BMP-ER Stress Pathways as Key Regulators of Neural- and Malignant Glioma-Stem Cell Homeostasis

(2013) Gaetano Gargiulo et al.   CANCER CELL

ATF3 Suppresses Metastasis of Bladder Cancer by Regulating Gelsolin-Mediated Remodeling of the Actin Cytoskeleton

(2013) X. Yuan et al.   CANCER RESEARCH

Zbtb7a suppresses prostate cancer through repression of a Sox9-dependent pathway for cellular senescence bypass and tumor invasion

(2013) Guocan Wang et al.   NATURE GENETICS

Adenylate Kinase-4 Is a Marker of Poor Clinical Outcomes That Promotes Metastasis of Lung Cancer by Downregulating the Transcription Factor ATF3

(2012) Y.-H. Jan et al.   CANCER RESEARCH

Mutant p53 oncogenic functions are sustained by Plk2 kinase through an autoregulatory feedback loop

(2012) Fabio Valenti et al.   CELL CYCLE

Mutant p53 cooperates with ETS2 to promote etoposide resistance

(2012) P. M. Do et al.   GENES & DEVELOPMENT

Mutant p53: one name, many proteins

(2012) W. A. Freed-Pastor et al.   GENES & DEVELOPMENT

The Stress Response Mediator ATF3 Represses Androgen Signaling by Binding the Androgen Receptor

(2012) H. Wang et al.   MOLECULAR AND CELLULAR BIOLOGY

SHARP1 suppresses breast cancer metastasis by promoting degradation of hypoxia-inducible factors

(2012) Marco Montagner et al.   NATURE

p53 mutations in cancer

(2012) Patricia A. J. Muller et al.   NATURE CELL BIOLOGY

A Pin1/Mutant p53 Axis Promotes Aggressiveness in Breast Cancer

(2011) Javier E. Girardini et al.   CANCER CELL

Expression of Id-1 Is Regulated by MCAM/MUC18: A Missing Link in Melanoma Progression

(2011) M. Zigler et al.   CANCER RESEARCH

KAI1Gene Is Engaged inNDRG1Gene-mediated Metastasis Suppression through the ATF3-NFκB Complex in Human Prostate Cancer

(2011) Wen Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Immunohistochemical staining patterns of p53 can serve as a surrogate marker for TP53 mutations in ovarian carcinoma: an immunohistochemical and nucleotide sequencing analysis

(2011) Anna Yemelyanova et al.   MODERN PATHOLOGY

TopBP1 Mediates Mutant p53 Gain of Function through NF-Y and p63/p73

(2011) K. Liu et al.   MOLECULAR AND CELLULAR BIOLOGY

Mutant p53 drives multinucleation and invasion through a process that is suppressed by ANKRD11

(2011) J E Noll et al.   ONCOGENE

Activating transcription factor-3 (ATF3) functions as a tumor suppressor in colon cancer and is up-regulated upon heat-shock protein 90 (Hsp90) inhibition

(2010) Christina Hackl et al.   BMC CANCER

Modulation of the Vitamin D3 Response by Cancer-Associated Mutant p53

(2010) Perry Stambolsky et al.   CANCER CELL

Activating Transcription Factor 3 Activates p53 by Preventing E6-associated Protein from Binding to E6

(2010) Hongbo Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MDM2 Mediates Ubiquitination and Degradation of Activating Transcription Factor 3

(2010) Pingli Mo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ATF3, an adaptive-response gene, enhances TGF  signaling and cancer-initiating cell features in breast cancer cells

(2010) X. Yin et al.   JOURNAL OF CELL SCIENCE

Opposing roles for calcineurin and ATF3 in squamous skin cancer

(2010) Xunwei Wu et al.   NATURE

Mutant p53 Drives Invasion by Promoting Integrin Recycling

(2009) Patricia A.J. Muller et al.   CELL

The inherent instability of mutant p53 is alleviated by Mdm2 or p16INK4a loss

(2008) T. Terzian et al.   GENES & DEVELOPMENT

KLF6 Induces Apoptosis in Prostate Cancer Cells through Up-regulation of ATF3

(2008) Xiangwei Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Activating Transcription Factor 3 on TAp73 Stability and Apoptosis in Paclitaxel-Treated Cervical Cancer Cells

(2008) Y. K. Oh et al.   MOLECULAR CANCER RESEARCH