Cell type-specific binding patterns reveal that TCF7L2 can be tethered to the genome by association with GATA3

At-Risk Variant in TCF7L2 for Type II Diabetes Increases Risk of Schizophrenia

(2011) Thomas Hansen et al.   BIOLOGICAL PSYCHIATRY

Lineage Regulators Direct BMP and Wnt Pathways to Cell-Specific Programs during Differentiation and Regeneration

(2011) Eirini Trompouki et al.   CELL

Chromatin occupancy of transcription factor 7-like 2 (TCF7L2) and its role in hepatic glucose metabolism

(2011) L. Norton et al.   DIABETOLOGIA

An alternative polyadenylation signal in TCF7L2 generates isoforms that inhibit T cell factor/lymphoid-enhancer factor (TCF/LEF)-dependent target genes

(2011) J. M. Locke et al.   DIABETOLOGIA

Wnt signaling meets internal dissent

(2011) E. A. Grove   GENES & DEVELOPMENT

Pioneer transcription factors: establishing competence for gene expression

(2011) K. S. Zaret et al.   GENES & DEVELOPMENT

Survival of pancreatic beta cells is partly controlled by a TCF7L2-p53-p53INP1-dependent pathway

(2011) Yuedan Zhou et al.   HUMAN MOLECULAR GENETICS

TCF7L2 splice variants have distinct effects on β-cell turnover and function

(2011) Olivier Le Bacquer et al.   HUMAN MOLECULAR GENETICS

Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors

(2011) Sayaka Sekiya et al.   NATURE

Characterization of the Contradictory Chromatin Signatures at the 3′ Exons of Zinc Finger Genes

(2011) Kimberly R. Blahnik et al.   PLoS One

W-ChIPeaks: a comprehensive web application tool for processing ChIP-chip and ChIP-seq data

(2010) Xun Lan et al.   BIOINFORMATICS

Molecular Function of TCF7L2: Consequences of TCF7L2 Splicing for Molecular Function and Risk for Type 2 Diabetes

(2010) Ola Hansson et al.   Current Diabetes Reports

Transcription Factor 7-Like 2 (TCF7L2) Polymorphism and Hyperglycemia in an Adult Italian Population-Based Cohort

(2010) R. Gambino et al.   DIABETES CARE

Disease-associated loci are significantly over-represented among genes bound by transcription factor 7-like 2 (TCF7L2) in vivo

(2010) J. Zhao et al.   DIABETOLOGIA

Locus co-occupancy, nucleosome positioning, and H3K4me1 regulate the functionality of FOXA2-, HNF4A-, and PDX1-bound loci in islets and liver

(2010) B. G. Hoffman et al.   GENOME RESEARCH

GATA3 Inhibits Breast Cancer Metastasis through the Reversal of Epithelial-Mesenchymal Transition

(2010) Wei Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GATA Switches as Developmental Drivers

(2010) Emery H. Bresnick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

(2010) Benjamin F Voight et al.   NATURE GENETICS

Alternative splicing of Tcf7l2 transcripts generates protein variants with differential promoter-binding and transcriptional activation properties at Wnt/β-catenin targets

(2010) Andreas Weise et al.   NUCLEIC ACIDS RESEARCH

TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions

(2010) M. P. Verzi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

W-ChIPMotifs: a web application tool for de novo motif discovery from ChIP-based high-throughput data

(2009) V. X. Jin et al.   BIOINFORMATICS

Unique splicing pattern of the TCF7L2 gene in human pancreatic islets

(2009) P. Osmark et al.   DIABETOLOGIA

Tissue-specific alternative splicing of TCF7L2

(2009) Ludmila Prokunina-Olsson et al.   HUMAN MOLECULAR GENETICS

Genomic Targets of the KRAB and SCAN Domain-containing Zinc Finger Protein 263

(2009) Seth Frietze et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GATA3 in development and cancer differentiation: Cells GATA have it!

(2009) Jonathan Chou et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Sole-Search: an integrated analysis program for peak detection and functional annotation using ChIP-seq data

(2009) Kimberly R. Blahnik et al.   NUCLEIC ACIDS RESEARCH

GATA-3 Links Tumor Differentiation and Dissemination in a Luminal Breast Cancer Model

(2008) Hosein Kouros-Mehr et al.   CANCER CELL

Wnt signaling inside the nucleus

(2008) Miki Shitashige et al.   CANCER SCIENCE

The Role of LEF/TCF Factors in Neoplastic Transformation

(2008) Mohamed El-Tanani et al.   CURRENT MOLECULAR MEDICINE

GATA-3 and the regulation of the mammary luminal cell fate

(2008) Hosein Kouros-Mehr et al.   CURRENT OPINION IN CELL BIOLOGY

Genome-Wide Pattern of TCF7L2/TCF4 Chromatin Occupancy in Colorectal Cancer Cells

(2008) P. Hatzis et al.   MOLECULAR AND CELLULAR BIOLOGY

Combinatorial patterns of histone acetylations and methylations in the human genome

(2008) Zhibin Wang et al.   NATURE GENETICS