Genetic analysis of variation in lifespan using a multiparental advanced intercross Drosophila mapping population

Novel loci and pathways significantly associated with longevity

(2016) Yi Zeng et al.   Scientific Reports

Long-Term Calorie Restriction Enhances Cellular Quality-Control Processes in Human Skeletal Muscle

(2016) Ling Yang et al.   Cell Reports

Nmdmc overexpression extends Drosophila lifespan and reduces levels of mitochondrial reactive oxygen species

(2015) Suyeun Yu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Promoting Health and Longevity through Diet: From Model Organisms to Humans

(2015) Luigi Fontana et al.   CELL

Longevity GWAS Using theDrosophilaGenetic Reference Panel

(2015) Dobril K. Ivanov et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

FlyBase: establishing a Gene Group resource forDrosophila melanogaster

(2015) Helen Attrill et al.   NUCLEIC ACIDS RESEARCH

Identification of Drosophila Mutants Affecting Defense to an Entomopathogenic Fungus

(2015) Hsiao-Ling Lu et al.   Scientific Reports

Efficient Test and Visualization of Multi-Set Intersections

(2015) Minghui Wang et al.   Scientific Reports

Distinct Shifts in Microbiota Composition during Drosophila Aging Impair Intestinal Function and Drive Mortality

(2015) Rebecca I. Clark et al.   Cell Reports

The Epigenetic Regulator G9a Mediates Tolerance to RNA Virus Infection in Drosophila

(2015) Sarah H. Merkling et al.   PLoS Pathogens

Cross-Tissue and Tissue-Specific eQTLs: Partitioning the Heritability of a Complex Trait

(2014) Jason M. Torres et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A gain-of-function screen to identify genes that reduce lifespan in the adult of Drosophila melanogaster

(2014) Minoru Nakayama et al.   BMC GENETICS

Ecdysone and Mediator Change Energy Metabolism to Terminate Proliferation in Drosophila Neural Stem Cells

(2014) Catarina C.F. Homem et al.   CELL

Ibf1 and Ibf2 are novel CP190-interacting proteins required for insulator function

(2014) S. Cuartero et al.   EMBO JOURNAL

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age

(2014) Joris Deelen et al.   HUMAN MOLECULAR GENETICS

Gene Ontology Consortium: going forward

(2014)   NUCLEIC ACIDS RESEARCH

Dissecting complex traits using the Drosophila Synthetic Population Resource

(2014) Anthony D. Long et al.   TRENDS IN GENETICS

The Innate Immune Response Transcription Factor Relish Is Necessary for Neurodegeneration in aDrosophilaModel of Ataxia-Telangiectasia

(2013) Andrew J. Petersen et al.   GENETICS

Genome-Wide Association Study of Extreme Longevity in Drosophila melanogaster

(2013) Molly K. Burke et al.   Genome Biology and Evolution

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

A holidic medium for Drosophila melanogaster

(2013) Matthew D W Piper et al.   NATURE METHODS

Properties and Modeling of GWAS when Complex Disease Risk Is Due to Non-Complementing, Deleterious Mutations in Genes of Large Effect

(2013) Kevin R. Thornton et al.   PLoS Genetics

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Ageing as a Risk Factor for Disease

(2012) Teresa Niccoli et al.   CURRENT BIOLOGY

Properties and Power of the Drosophila Synthetic Population Resource for the Routine Dissection of Complex Traits

(2012) Elizabeth G. King et al.   GENETICS

Genetic dissection of a model complex trait using the Drosophila Synthetic Population Resource

(2012) E. G. King et al.   GENOME RESEARCH

Differential analysis of gene regulation at transcript resolution with RNA-seq

(2012) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Genetic Signatures of Exceptional Longevity in Humans

(2012) Paola Sebastiani et al.   PLoS One

Quantitative trait loci for longevity in heat-stressed Drosophila melanogaster

(2011) Raquel Defays et al.   EXPERIMENTAL GERONTOLOGY

The ALS-associated proteins FUS and TDP-43 function together to affect Drosophila locomotion and life span

(2011) Ji-Wu Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Drosophila sbo regulates lifespan through its function in the synthesis of coenzyme Q in vivo

(2011) Jiyong Liu et al.   Journal of Genetics and Genomics

Increased transsulfuration mediates longevity and dietary restriction in Drosophila

(2011) H. Kabil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Improving RNA-Seq expression estimates by correcting for fragment bias

(2011) Adam Roberts et al.   GENOME BIOLOGY

Dissecting the genetics of longevity inDrosophila melanogaster

(2010) Annalise B. Paaby et al.   FLY

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Genetics and genomics of human ageing

(2010) H. E. Wheeler et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Quantitative and Molecular Genetic Analyses of Mutations Increasing Drosophila Life Span

(2010) Michael M. Magwire et al.   PLoS Genetics

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

Extension of Drosophila Life Span by RNAi of the Mitochondrial Respiratory Chain

(2009) Jeffrey M. Copeland et al.   CURRENT BIOLOGY

Designing Genome-Wide Association Studies: Sample Size, Power, Imputation, and the Choice of Genotyping Chip

(2009) Chris C. A. Spencer et al.   PLoS Genetics

Power for Genetic Association Study of Human Longevity Using the Case-Control Design

(2008) Q. Tan et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Diet and Aging

(2008) Matthew D.W. Piper et al.   Cell Metabolism

Overexpression of Glucose-6-phosphate Dehydrogenase Extends the Life Span ofDrosophila melanogaster

(2008) Susan K. Legan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Revealing the architecture of gene regulation: the promise of eQTL studies

(2008) Yoav Gilad et al.   TRENDS IN GENETICS

Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice

(2007) Colin Selman et al.   FASEB JOURNAL