The ALS-associated proteins FUS and TDP-43 function together to affect Drosophila locomotion and life span
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Title
The ALS-associated proteins FUS and TDP-43 function together to affect Drosophila locomotion and life span
Authors
Keywords
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Journal
JOURNAL OF CLINICAL INVESTIGATION
Volume 121, Issue 10, Pages 4118-4126
Publisher
American Society for Clinical Investigation
Online
2011-09-02
DOI
10.1172/jci57883
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Note: Only part of the references are listed.- Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice
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- (2010) Dorothee Dormann et al. EMBO JOURNAL
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- (2010) Daryl A. Bosco et al. HUMAN MOLECULAR GENETICS
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- (2010) C. Lagier-Tourenne et al. HUMAN MOLECULAR GENETICS
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- (2010) Mariely DeJesus-Hernandez et al. HUMAN MUTATION
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- (2010) Ian RA Mackenzie et al. LANCET NEUROLOGY
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- (2010) Andrew C. Elden et al. NATURE
- Both cytoplasmic and nuclear accumulations of the protein are neurotoxic in Drosophila models of TDP-43 proteinopathies
- (2010) Laetitia Miguel et al. NEUROBIOLOGY OF DISEASE
- RNA processing pathways in amyotrophic lateral sclerosis
- (2010) Marka van Blitterswijk et al. NEUROGENETICS
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- (2010) Yoshihiro Kino et al. NUCLEIC ACIDS RESEARCH
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- (2010) S.-C. Ling et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2010) Y. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration
- (2010) Hans Wils et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rethinking ALS: The FUS about TDP-43
- (2009) Clotilde Lagier-Tourenne et al. CELL
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- (2009) Fabian Feiguin et al. FEBS LETTERS
- Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo
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- Global Analysis of TDP-43 Interacting Proteins Reveals Strong Association with RNA Splicing and Translation Machinery
- (2009) Brian D. Freibaum et al. JOURNAL OF PROTEOME RESEARCH
- TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration
- (2009) I. Wegorzewska et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6
- (2009) C. Vance et al. SCIENCE
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- ADrosophilaModel for Amyotrophic Lateral Sclerosis Reveals Motor Neuron Damage by Human SOD1
- (2008) Melanie R. Watson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tools for neuroanatomy and neurogenetics in Drosophila
- (2008) B. D. Pfeiffer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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