Microbial degradation of steroid sex hormones: implications for environmental and ecological studies

Steroids originating from bacterial bile acid degradation affect Caenorhabditis elegans and indicate potential risks for the fauna of manured soils

(2019) M. N. Mendelski et al.   Scientific Reports

Occurrence, fate and risk assessment of androgens in ten wastewater treatment plants and receiving rivers of South China

(2018) Jin-Na Zhang et al.   CHEMOSPHERE

Excreted Steroids in Vertebrate Social Communication

(2018) Wayne I. Doyle et al.   JOURNAL OF NEUROSCIENCE

IpdAB, a virulence factor inMycobacterium tuberculosis, is a cholesterol ring-cleaving hydrolase

(2018) Adam M. Crowe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unexpected metabolic disorders induced by endocrine disruptors inXenopus tropicalisprovide new lead for understanding amphibian decline

(2018) Christophe Regnault et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Determination of two progestin metabolites (17α-hydroxypregnanolone and pregnanediol) and different classes of steroids (androgens, estrogens, corticosteroids, progestins) in rivers and wastewaters by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS)

(2018) Kun Zhang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Two synthetic progestins and natural progesterone are responsible for most of the progestagenic activities in municipal wastewater treatment plant effluents in the Czech and Slovak republics

(2018) Pavel Šauer et al.   WATER RESEARCH

Trace analysis of 61 natural and synthetic progestins in river water and sewage effluents by ultra-high performance liquid chromatography–tandem mass spectrometry

(2018) Xiaoyan Shen et al.   WATER RESEARCH

Metagenomes Reveal Global Distribution of Bacterial Steroid Catabolism in Natural, Engineered, and Host Environments

(2018) Johannes Holert et al.   mBio

Contamination and Risk Assessment of Estrogens in Livestock Manure: A Case Study in Jiangsu Province, China

(2018) Pengcheng Xu et al.   International Journal of Environmental Research and Public Health

Functional Characterization of Three Specific Acyl-Coenzyme A Synthetases Involved in Anaerobic Cholesterol Degradation in Sterolibacterium denitrificans Chol1S

(2018) Markus Warnke et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Estrogen Degraders and Estrogen Degradation Pathway Identified in an Activated Sludge

(2018) Yi-Lung Chen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Steroid degradation in Comamonas testosteroni TA441: identification of metabolites and the genes involved in the reactions necessary before D-ring cleavage

(2018) Masae Horinouchi et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Metabolites Involved in Aerobic Degradation of the A and B Rings of Estrogen

(2018) Kan Wu et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The 7α-hydroxysteroid dehydratase Hsh2 is essential for anaerobic degradation of the steroid skeleton of 7α-hydroxyl bile salts in the novel denitrifying bacterium Azoarcus sp. strain Aa7

(2018) Onur Yücel et al.   ENVIRONMENTAL MICROBIOLOGY

Sterol and Sphingoid Glycoconjugates from Microalgae

(2018) Valentin Stonik et al.   Marine Drugs

Microbial Functional Responses to Cholesterol Catabolism in Denitrifying Sludge

(2018) Sean Ting-Shyang Wei et al.   mSystems

A patchwork pathway for oxygenase-independent degradation of side chain containing steroids

(2017) Markus Warnke et al.   ENVIRONMENTAL MICROBIOLOGY

Warming modulates the effects of the endocrine disruptor progestin levonorgestrel on the zebrafish fitness, ovary maturation kinetics and reproduction success

(2017) P.G. Cardoso et al.   ENVIRONMENTAL POLLUTION

Sex Steroids Mediate Bidirectional Interactions Between Hosts and Microbes

(2017) Landon G. vom Steeg et al.   HORMONES AND BEHAVIOR

Functional characterization of 3-ketosteroid 9α-hydroxylases in Rhodococcus ruber strain chol-4

(2017) Govinda Guevara et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Regio- and stereoselective reduction of 17-oxosteroids to 17β-hydroxysteroids by a yeast strain Zygowilliopsis sp. WY7905

(2017) Yuanyuan Liu et al.   STEROIDS

Catabolism of the Last Two Steroid Rings in Mycobacterium tuberculosis and Other Bacteria

(2017) Adam M. Crowe et al.   mBio

Biochemical Mechanisms and Microorganisms Involved in Anaerobic Testosterone Metabolism in Estuarine Sediments

(2017) Chao-Jen Shih et al.   Frontiers in Microbiology

Interaction of gut microbiota with bile acid metabolism and its influence on disease states

(2016) Christopher Staley et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Plant sterols: Diversity, biosynthesis, and physiological functions

(2016) J. N. Valitova et al.   BIOCHEMISTRY-MOSCOW

Removal of endocrine disrupting compounds from wastewater by microalgae co-immobilized in alginate beads

(2016) Alba Solé et al.   CHEMOSPHERE

Occurrence of selected estrogenic compounds and estrogenic activity in surface water and sediment of Langat River (Malaysia)

(2016) Sarva Mangala Praveena et al.   ENVIRONMENTAL MONITORING AND ASSESSMENT

Distribution and estrogenic potential of endocrine disrupting chemicals (EDCs) in estuarine sediments from Mumbai, India

(2016) M. Tiwari et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Noncontraceptive use of oral combined hormonal contraceptives in polycystic ovary syndrome—risks versus benefits

(2016) Anuja Dokras   FERTILITY AND STERILITY

Integrated multi-omics analyses reveal the biochemical mechanisms and phylogenetic relevance of anaerobic androgen biodegradation in the environment

(2016) Fu-Chun Yang et al.   ISME Journal

MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0 for Bigger Datasets

(2016) Sudhir Kumar et al.   MOLECULAR BIOLOGY AND EVOLUTION

Delineation of Steroid-Degrading Microorganisms through Comparative Genomic Analysis

(2016) Lee H. Bergstrand et al.   mBio

Identification of Comamonas testosteroni as an androgen degrader in sewage

(2016) Yi-Lung Chen et al.   Scientific Reports

Identification and isolation of a regulator protein for 3,17β-HSD expressional regulation in Comamonas testosteroni

(2015) Yin Wu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Isolation and identification of a repressor TetR for 3,17β-HSD expressional regulation in Comamonas testosteroni

(2015) Tianyuan Pan et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Biocatalytic conversion of lignin to aromatic dicarboxylic acids in Rhodococcus jostii RHA1 by re-routing aromatic degradation pathways

(2015) Zoe Mycroft et al.   GREEN CHEMISTRY

Identification of estrone-degrading Betaproteobacteria in activated sludge by microautoradiography fluorescentin situhybridization

(2015) F. Kurisu et al.   LETTERS IN APPLIED MICROBIOLOGY

A review of steroids fromSarcophytonspecies

(2015) Muhammad Sulaiman Zubair et al.   NATURAL PRODUCT RESEARCH

Suburbanization, estrogen contamination, and sex ratio in wild amphibian populations

(2015) Max R. Lambert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Occurrence, source analysis and risk assessment of androgens, glucocorticoids and progestagens in the Hailing Bay region, South China Sea

(2015) Shan Liu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Occurrence and spatial distribution of EDCs and related compounds in waters and sediments of Iberian rivers

(2015) Marina Gorga et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Novel Inhibitors of Cholesterol Degradation in Mycobacterium tuberculosis Reveal How the Bacterium’s Metabolism Is Constrained by the Intracellular Environment

(2015) Brian C. VanderVen et al.   PLoS Pathogens

3-Ketosteroid 9α-hydroxylase enzymes: Rieske non-heme monooxygenases essential for bacterial steroid degradation

(2014) Mirjan Petrusma et al.   ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY

Anoxic Androgen Degradation by the Denitrifying Bacterium Sterolibacterium denitrificans via the 2,3-seco Pathway

(2014) Po-Hsiang Wang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Occurrence of 17α-ethynylestradiol (EE2) in the environment and effect on exposed biota: a review

(2014) Ahmad Zaharin Aris et al.   ENVIRONMENT INTERNATIONAL

Evidence of distinct pathways for bacterial degradation of the steroid compound cholate suggests the potential for metabolic interactions by interspecies cross-feeding

(2014) Johannes Holert et al.   ENVIRONMENTAL MICROBIOLOGY

17β-Estradiol Causes Abnormal Development in Embryos of the Viviparous Eelpout

(2014) Jane E. Morthorst et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Sources, concentrations, and exposure effects of environmental gestagens on fish and other aquatic wildlife, with an emphasis on reproduction

(2014) Edward F. Orlando et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Structural and Functional Characterization of a Ketosteroid Transcriptional Regulator ofMycobacterium tuberculosis

(2014) Adam M. Crowe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Substrate Uptake and Subcellular Compartmentation of Anoxic Cholesterol Catabolism inSterolibacterium denitrificans

(2014) Ching-Wen Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Estimating Estrogen Release and Load from Humans and Livestock in Shanghai, China

(2014) Xiaowei Liu et al.   JOURNAL OF ENVIRONMENTAL QUALITY

Microbial degradation of steroidal estrogens

(2013) Chang-Ping Yu et al.   CHEMOSPHERE

Occurrence, removal and bioaccumulation of steroid estrogens in Dianchi Lake catchment, China

(2013) Bin Huang et al.   ENVIRONMENT INTERNATIONAL

Analysis of natural-occurring and synthetic sexual hormones in sludge-amended soils by matrix solid-phase dispersion and isotope dilution gas chromatography–tandem mass spectrometry

(2013) Beatriz Albero et al.   JOURNAL OF CHROMATOGRAPHY A

Anaerobic and aerobic cleavage of the steroid core ring structure bySteroidobacter denitrificans

(2013) Po-Hsiang Wang et al.   JOURNAL OF LIPID RESEARCH

Microbial steroid transformations: current state and prospects

(2012) Marina V. Donova et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Biotransformation of 17α- and 17β-estradiol in aerobic soils

(2012) Michael L. Mashtare et al.   CHEMOSPHERE

Odorant tuning of olfactory crypt cells from juvenile and adult rainbow trout

(2012) A. Bazaes et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Molecular characterization of three 3-ketosteroid-Δ1-dehydrogenase isoenzymes of Rhodococcus ruber strain Chol-4

(2012) Laura Fernández de las Heras et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

FadD3 is an acyl-CoA synthetase that initiates catabolism of cholesterol rings C and D in actinobacteria

(2012) Israël Casabon et al.   MOLECULAR MICROBIOLOGY

Steroids in a typical swine farm and their release into the environment

(2012) Shan Liu et al.   WATER RESEARCH

Fate of estrogenic hormones in wastewater and sludge treatment: A review of properties and analytical detection techniques in sludge matrix

(2012) Hanna Hamid et al.   WATER RESEARCH

Behaviors of Glucocorticoids, Androgens and Progestogens in a Municipal Sewage Treatment Plant: Comparison to Estrogens

(2011) Zhanlan Fan et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Multiplicity of 3-Ketosteroid-9 -Hydroxylase Enzymes in Rhodococcus rhodochrous DSM43269 for Specific Degradation of Different Classes of Steroids

(2011) M. Petrusma et al.   JOURNAL OF BACTERIOLOGY

A Novel Testosterone Catabolic Pathway in Bacteria

(2011) Y.-L. Leu et al.   JOURNAL OF BACTERIOLOGY

Activity of 3-Ketosteroid 9α-Hydroxylase (KshAB) Indicates Cholesterol Side Chain and Ring Degradation Occur Simultaneously inMycobacterium tuberculosis

(2011) Jenna K. Capyk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Relationships between Sex Hormones and Sexual Function in Middle-Aged and Older European Men

(2011) Daryl B. O'Connor et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Steroid-transforming enzymes in fungi

(2011) Katja Kristan et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Identification of a new steroid degrading bacterial strain H5 from the Baltic Sea and isolation of two estradiol inducible genes

(2011) Yingying Sang et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

How hydrophobic molecules traverse the outer membranes of Gram-negative bacteria

(2011) M. C. Wiener et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distribution and Functions of Sterols and Sphingolipids

(2011) J. T. Hannich et al.   Cold Spring Harbor Perspectives in Biology

A randomized controlled trial of low-dose hormone therapy on myocardial ischemia in postmenopausal women with no obstructive coronary artery disease: Results from the National Institutes of Health/National Heart, Lung, and Blood Institute–sponsored Women's Ischemia Syndrome Evaluation (WISE)

(2010) C. Noel Bairey Merz et al.   AMERICAN HEART JOURNAL

Bacterial degradation of bile salts

(2010) Bodo Philipp   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Characterization of the steroid degrading bacterium S19-1 from the Baltic Sea at Kiel, Germany

(2010) Tingdi Zhang et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Biotransformation of 17α-methyltestosterone in sediment under different electron acceptor conditions

(2010) Supreeda Homklin et al.   CHEMOSPHERE

Are Oral Contraceptives a Significant Contributor to the Estrogenicity of Drinking Water?†

(2010) Amber Wise et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Steroid degradation in Comamonas testosteroni

(2010) Masae Horinouchi et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Initial steps in anoxic testosterone degradation by Steroidobacter denitrificans

(2010) Y.-R. Chiang et al.   MICROBIOLOGY-SGM

Mycobacterium tuberculosis CYP125A1, a steroid C27 monooxygenase that detoxifies intracellularly generated cholest-4-en-3-one

(2010) Hugues Ouellet et al.   MOLECULAR MICROBIOLOGY

High estrogen concentrations in receiving river discharge from a concentrated livestock feedlot

(2010) Te-San Chen et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Concentration-dependent response of estrone-degrading bacterial community in activated sludge analyzed by microautoradiography-fluorescence in situ hybridization

(2010) Parinda Thayanukul et al.   WATER RESEARCH

Occurrence of androgens and progestogens in wastewater treatment plants and receiving river waters: Comparison to estrogens

(2010) Hong Chang et al.   WATER RESEARCH

Rhodococcus rhodochrous DSM 43269 3-Ketosteroid 9 -Hydroxylase, a Two-Component Iron-Sulfur-Containing Monooxygenase with Subtle Steroid Substrate Specificity

(2009) M. Petrusma et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Estrogen removal from treated municipal effluent in small-scale constructed wetland with different depth

(2009) Hai-Liang Song et al.   BIORESOURCE TECHNOLOGY

Occurrence of pharmaceuticals and personal care products along the West Prong Little Pigeon River in east Tennessee, USA

(2009) Chang-Ping Yu et al.   CHEMOSPHERE

Morphological, Physiological, and Molecular Characterization of a Newly Isolated Steroid-Degrading Actinomycete, Identified as Rhodococcus ruber Strain Chol-4

(2009) Laura Fernández de las Heras et al.   CURRENT MICROBIOLOGY

Removal of Aqueous 17α-Ethinylestradiol by Rhodococcus Species

(2009) Devin O'Grady et al.   ENVIRONMENTAL ENGINEERING SCIENCE

Determination and Source Apportionment of Five Classes of Steroid Hormones in Urban Rivers

(2009) Hong Chang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

EFFECTS OF SYNTHETIC GESTAGENS ON FISH REPRODUCTION

(2009) Jana Zeilinger et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Endozoicomonas montiporae sp. nov., isolated from the encrusting pore coral Montipora aequituberculata

(2009) C. S. Yang et al.   INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Organization of Cytochrome P450 Enzymes Involved in Sex Steroid Synthesis

(2009) Slavica Praporski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Degradation of natural estrogen and identification of the metabolites produced by soil isolates of Rhodococcus sp. and Sphingomonas sp.

(2009) Futoshi Kurisu et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Cytochrome P450 125 (CYP125) catalyses C26-hydroxylation to initiate sterol side-chain degradation inRhodococcus jostiiRHA1

(2009) Kamila Z. Rosłoniec et al.   MOLECULAR MICROBIOLOGY

An ABC transport system that maintains lipid asymmetry in the Gram-negative outer membrane

(2009) J. C. Malinverni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biodegradation of endocrine disrupting compounds in harbour seawater and sediments

(2009) Brian J. Robinson et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Studies of a Ring-Cleaving Dioxygenase Illuminate the Role of Cholesterol Metabolism in the Pathogenesis of Mycobacterium tuberculosis

(2009) Katherine C. Yam et al.   PLoS Pathogens

Pheromone Communication in Amphibians and Reptiles

(2008) Lynne D. Houck   Annual Review of Physiology

11-Ketotestosterone Stimulates Putative Sex Pheromone Production in the Male Peacock Blenny, Salaria pavo (Risso 1810)1

(2008) Rui M. Serrano et al.   BIOLOGY OF REPRODUCTION

Environmental estrogenic effects and gonadal development in wild goldfish (Carassius auratus)

(2008) Chun-Ri Li et al.   ENVIRONMENTAL MONITORING AND ASSESSMENT

Reproductive Disruption in Fish Downstream from an Estrogenic Wastewater Effluent

(2008) Alan M. Vajda et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

PULP AND PAPER MILL EFFLUENT TREATMENTS HAVE DIFFERENTIAL ENDOCRINE-DISRUPTING EFFECTS ON RAINBOW TROUT

(2008) Rodrigo Orrego et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Steroidobacter denitrificans gen. nov., sp. nov., a steroidal hormone-degrading gammaproteobacterium

(2008) M. Fahrbach et al.   INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

The Actinobacterialmce4Locus Encodes a Steroid Transporter

(2008) William W. Mohn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mycobacterial persistence requires the utilization of host cholesterol

(2008) A. K. Pandey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of the phylogenetic diversity of estrone-degrading bacteria in activated sewage sludge using microautoradiography–fluorescence in situ hybridization

(2008) Kaisai Zang et al.   SYSTEMATIC AND APPLIED MICROBIOLOGY