FadD3 is an acyl-CoA synthetase that initiates catabolism of cholesterol rings C and D in actinobacteria

Genomic and Transcriptomic Studies of an RDX (Hexahydro-1,3,5-Trinitro-1,3,5-Triazine)-Degrading Actinobacterium

(2012) Hao-Ping Chen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Cholesterol Catabolism by Mycobacterium tuberculosis Requires Transcriptional and Metabolic Adaptations

(2012) Jennifer E. Griffin et al.   CHEMISTRY & BIOLOGY

Two Transporters Essential for Reassimilation of Novel Cholate Metabolites by Rhodococcus jostii RHA1

(2012) K. Swain et al.   JOURNAL OF BACTERIOLOGY

Gene Cluster Encoding Cholate Catabolism in Rhodococcus spp.

(2012) W. W. Mohn et al.   JOURNAL OF BACTERIOLOGY

FadD19 of Rhodococcus rhodochrous DSM43269, a Steroid-Coenzyme A Ligase Essential for Degradation of C-24 Branched Sterol Side Chains

(2011) M. H. Wilbrink et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Reversible Acetylation and Inactivation ofMycobacterium tuberculosisAcetyl-CoA Synthetase Is Dependent on cAMP

(2011) Hua Xu et al.   BIOCHEMISTRY

Pathway Profiling inMycobacterium tuberculosis

(2011) Suzanne T. Thomas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activity of 3-Ketosteroid 9α-Hydroxylase (KshAB) Indicates Cholesterol Side Chain and Ring Degradation Occur Simultaneously inMycobacterium tuberculosis

(2011) Jenna K. Capyk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cholesterol catabolism as a therapeutic target in Mycobacterium tuberculosis

(2011) Hugues Ouellet et al.   TRENDS IN MICROBIOLOGY

The Steroid Catabolic Pathway of the Intracellular Pathogen Rhodococcus equi Is Important for Pathogenesis and a Target for Vaccine Development

(2011) R. van der Geize et al.   PLoS Pathogens

High-Resolution Phenotypic Profiling Defines Genes Essential for Mycobacterial Growth and Cholesterol Catabolism

(2011) Jennifer E. Griffin et al.   PLoS Pathogens

Mycobacterium tuberculosis Wears What It Eats

(2010) David G. Russell et al.   Cell Host & Microbe

Caseation of human tuberculosis granulomas correlates with elevated host lipid metabolism

(2010) Mi-Jeong Kim et al.   EMBO Molecular Medicine

Functional Redundancy of Steroid C26-monooxygenase Activity inMycobacterium tuberculosisRevealed by Biochemical and Genetic Analyses

(2010) Jonathan B. Johnston et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Flavin-dependent Monooxygenase fromMycobacterium tuberculosisInvolved in Cholesterol Catabolism

(2010) Carola Dresen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cholesterol utilization in mycobacteria is controlled by two TetR-type transcriptional regulators: kstR and kstR2

(2010) S. L. Kendall et al.   MICROBIOLOGY-SGM

Functional Genetic Diversity among Mycobacterium tuberculosis Complex Clinical Isolates: Delineation of Conserved Core and Lineage-Specific Transcriptomes during Intracellular Survival

(2010) Susanne Homolka et al.   PLoS Pathogens

A Thiolase of Mycobacterium tuberculosis Is Required for Virulence and Production of Androstenedione and Androstadienedione from Cholesterol

(2009) N. M. Nesbitt et al.   INFECTION AND IMMUNITY

In Salmonella enterica, 2-Methylcitrate Blocks Gluconeogenesis

(2009) C. J. Rocco et al.   JOURNAL OF BACTERIOLOGY

igr Genes and Mycobacterium tuberculosis Cholesterol Metabolism

(2009) J. C. Chang et al.   JOURNAL OF BACTERIOLOGY

Characterization of 3-Ketosteroid 9α-Hydroxylase, a Rieske Oxygenase in the Cholesterol Degradation Pathway ofMycobacterium tuberculosis

(2009) Jenna K. Capyk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of a Carbon-Carbon Hydrolase from Mycobacterium tuberculosis Involved in Cholesterol Metabolism

(2009) Nathan A. Lack et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

3-Ketosteroid 9α-hydroxylase is an essential factor in the pathogenesis ofMycobacterium tuberculosis

(2009) Yanmin Hu et al.   MOLECULAR MICROBIOLOGY

Mechanistic and functional insights into fatty acid activation in Mycobacterium tuberculosis

(2009) Pooja Arora et al.   Nature Chemical Biology

Studies of a Ring-Cleaving Dioxygenase Illuminate the Role of Cholesterol Metabolism in the Pathogenesis of Mycobacterium tuberculosis

(2009) Katherine C. Yam et al.   PLoS Pathogens

The Actinobacterialmce4Locus Encodes a Steroid Transporter

(2008) William W. Mohn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mycobacterial persistence requires the utilization of host cholesterol

(2008) A. K. Pandey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA