Microbial steroid transformations: current state and prospects

The glucocorticoid contribution to obesity

(2016) Sarah J. Spencer et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Neurology of endocrine disease

(2013) M. Douglas   CLINICAL MEDICINE

Cholesterol metabolism in Mycobacterium smegmatis

(2012) Iria Uhía et al.   Environmental Microbiology Reports

FadD19 of Rhodococcus rhodochrous DSM43269, a Steroid-Coenzyme A Ligase Essential for Degradation of C-24 Branched Sterol Side Chains

(2011) M. H. Wilbrink et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Cholesterol Degradation by Gordonia cholesterolivorans

(2011) O. Drzyzga et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Biotechnological Production of 20-alpha-Dihydrodydrogesterone at Pilot Scale

(2011) Julia Maria Naumann et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Transformation of Δ4-3-ketosteroids by free and immobilized cells of Rhodococcus erythropolis actinobacterium

(2011) N. V. Carpova-Rodina et al.   APPLIED BIOCHEMISTRY AND MICROBIOLOGY

Hydroxylation of steroids by Curvularia lunata mycelium in the presence of methyl-β-cyclodextrine

(2011) V. A. Andrushina et al.   APPLIED BIOCHEMISTRY AND MICROBIOLOGY

Transformation of prednisolone to a 20β-hydroxy prednisolone compound by Streptomyces roseochromogenes TS79

(2011) Wenquan Zhang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Effects of hydroxypropyl-β-cyclodextrin on cell growth, activity, and integrity of steroid-transforming Arthrobacter simplex and Mycobacterium sp.

(2011) Yanbing Shen et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Microbial Baeyer–Villiger oxidation of steroidal ketones using Beauveria bassiana: Presence of an 11α-hydroxyl group essential to generation of D-homo lactones

(2011) Alina Świzdor et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

11α-Hydroxylation of 16α,17-epoxyprogesterone by Rhizopus nigricans in a biphasic ionic liquid aqueous system

(2011) Dong-Xiang Wu et al.   BIORESOURCE TECHNOLOGY

Enhanced whole-cell biodehydrogenation of 11β-hydroxyl medroxyprogesterone in a biphasic system containing ionic liquid

(2011) Jun-Yao He et al.   BIOTECHNOLOGY AND BIOPROCESS ENGINEERING

Redox Reactions Catalyzed by Isolated Enzymes

(2011) Daniela Monti et al.   CHEMICAL REVIEWS

Steroid degradation and two steroid-inducible enzymes in the marine bacterium H5

(2011) Yingying Sang et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Biotransformation of methyltestosterone by the filamentous fungus Mucor racemosus

(2011) M. Torshabi et al.   CHEMISTRY OF NATURAL COMPOUNDS

Initial step in the catabolism of cholesterol by Mycobacterium smegmatis mc2155

(2011) I. Uhía et al.   ENVIRONMENTAL MICROBIOLOGY

Activity of 3-Ketosteroid 9α-Hydroxylase (KshAB) Indicates Cholesterol Side Chain and Ring Degradation Occur Simultaneously inMycobacterium tuberculosis

(2011) Jenna K. Capyk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cholesterol oxidase ChoD is not a critical enzyme accounting for oxidation of sterols to 3-keto-4-ene steroids in fast-growing Mycobacterium sp. VKM Ac-1815D

(2011) Tatyana V. Ivashina et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Hydroxysteroid dehydrogenases (HSDs) in bacteria – A bioinformatic perspective

(2011) Michael Kisiela et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Steroid-transforming enzymes in fungi

(2011) Katja Kristan et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Characterization of the KstR-dependent promoter of the gene for the first step of the cholesterol degradative pathway in Mycobacterium smegmatis

(2011) I. Uhia et al.   MICROBIOLOGY-SGM

Female reproductive steroids and neuronal excitability

(2011) C. Finocchi et al.   NEUROLOGICAL SCIENCES

Paradoxical effects of GABA-A modulators may explain sex steroid induced negative mood symptoms in some persons

(2011) T. Bäckström et al.   NEUROSCIENCE

Neuroactive steroids in affective disorders: target for novel antidepressant or anxiolytic drugs?

(2011) C. Schüle et al.   NEUROSCIENCE

Neuroactive steroids: focus on human brain

(2011) R.C. Melcangi et al.   NEUROSCIENCE

Hydroxylation of DHEA, androstenediol and epiandrosterone by Mortierella isabellina AM212. Evidence indicating that both constitutive and inducible hydroxylases catalyze 7α- as well as 7β-hydroxylations of 5-ene substrates

(2011) Teresa Kołek et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Comparative Genomics of Cell Envelope Components in Mycobacteria

(2011) Ruma Banerjee et al.   PLoS One

Azido analogs of neuroactive steroids

(2011) Lukáš Vidrna et al.   STEROIDS

Hydroxylation of steroids by Fusarium oxysporum, Exophiala jeanselmei and Ceratocystis paradoxa

(2011) Patrice C. Peart et al.   STEROIDS

Entrapment of mycelial fragments in calcium alginate: A general technique for the use of immobilized filamentous fungi in biocatalysis

(2011) Patrice C. Peart et al.   STEROIDS

Cholesterol catabolism as a therapeutic target in Mycobacterium tuberculosis

(2011) Hugues Ouellet et al.   TRENDS IN MICROBIOLOGY

Effect of inoculation strategies, substrate to biomass ratio and nitrogen sources on the bioconversion of wood sterols by Mycobacterium sp.

(2011) Araceli Olivares et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Distribution and Functions of Sterols and Sphingolipids

(2011) J. T. Hannich et al.   Cold Spring Harbor Perspectives in Biology

The Steroid Catabolic Pathway of the Intracellular Pathogen Rhodococcus equi Is Important for Pathogenesis and a Target for Vaccine Development

(2011) R. van der Geize et al.   PLoS Pathogens

Inactivation and Augmentation of the Primary 3-Ketosteroid- 1- Dehydrogenase in Mycobacterium neoaurum NwIB-01: Biotransformation of Soybean Phytosterols to 4-Androstene- 3,17-Dione or 1,4-Androstadiene-3,17-Dione

(2010) W. Wei et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

7α-Hydroxylation of steroid 5-olefins by mold fungi

(2010) V. A. Andryushina et al.   APPLIED BIOCHEMISTRY AND MICROBIOLOGY

Bioconversion of C19- and C21-steroids with parent and mutant strains of Curvularia lunata

(2010) V. V. Kollerov et al.   APPLIED BIOCHEMISTRY AND MICROBIOLOGY

Bacterial degradation of bile salts

(2010) Bodo Philipp   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Genetic and hormonal factors in female-biased autoimmunity

(2010) Anatoly V. Rubtsov et al.   AUTOIMMUNITY REVIEWS

From structure and functions of steroidogenic enzymes to new technologies of gene engineering

(2010) L. A. Novikova et al.   BIOCHEMISTRY-MOSCOW

Cholesterol biotransformation to androsta-1,4-diene-3,17-dione by growing cells of Chryseobacterium gleum

(2010) Priti N. Chaudhari et al.   BIOTECHNOLOGY LETTERS

Development of a continuous steroid biotransformation process and product extraction within microchannel system

(2010) P. Žnidaršič-Plazl et al.   CATALYSIS TODAY

Minireview: Aldosterone and Mineralocorticoid Receptors: Past, Present, and Future

(2010) John W. Funder   ENDOCRINOLOGY

Anaerobic testosterone degradation in Steroidobacter denitrificans – Identification of transformation products

(2010) Michael Fahrbach et al.   ENVIRONMENTAL POLLUTION

Steroid bioconversion: Towards green processes

(2010) Marco P.C. Marques et al.   FOOD AND BIOPRODUCTS PROCESSING

A Flavin-dependent Monooxygenase fromMycobacterium tuberculosisInvolved in Cholesterol Catabolism

(2010) Carola Dresen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The microbial formation of lactones from dehydroepiandrosterone

(2010) Tatyana G. Lobastova et al.   JOURNAL OF BIOTECHNOLOGY

Discovery of a steroid 11α-hydroxylase from Rhizopus oryzae and its biotechnological application

(2010) Š. Petrič et al.   JOURNAL OF BIOTECHNOLOGY

Challenges of steroid biotransformation with human cytochrome P450 monooxygenase CYP21 using resting cells of recombinant Schizosaccharomyces pombe

(2010) Daniela Zehentgruber et al.   JOURNAL OF BIOTECHNOLOGY

Human 20α-hydroxysteroid dehydrogenase (AKR1C1)-dependent biotransformation with recombinant fission yeast Schizosaccharomyces pombe

(2010) Julia Maria Naumann et al.   JOURNAL OF BIOTECHNOLOGY

Bioconversion of soysterols to androstenedione by Mycobacterium fortuitum subsp. fortuitum NCIM 5239, a mutant derived from total sterol degrader strain

(2010) Vrushali Gulla et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Hydroxylation of steroid compounds by Gelasinospora retispora

(2010) Masahiro Koshimura et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Steroid degradation genes in Comamonas testosteroni TA441: Isolation of genes encoding a Δ4(5)-isomerase and 3α- and 3β-dehydrogenases and evidence for a 100kb steroid degradation gene hot spot

(2010) Masae Horinouchi et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Hormonal influences in multiple sclerosis: New therapeutic benefits for steroids

(2010) Martine El-Etr et al.   MATURITAS

ChoG is the main inducible extracellular cholesterol oxidase of Rhodococcus sp. strain CECT3014

(2010) Laura Fernández de las Heras et al.   MICROBIOLOGICAL RESEARCH

Cholesterol utilization in mycobacteria is controlled by two TetR-type transcriptional regulators: kstR and kstR2

(2010) S. L. Kendall et al.   MICROBIOLOGY-SGM

Origin and diversification of steroids: Co-evolution of enzymes and nuclear receptors

(2010) Michael E. Baker   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Control of mammary stem cell function by steroid hormone signalling

(2010) Marie-Liesse Asselin-Labat et al.   NATURE

Microbial side-chain degradation of ergosterol and its 3-substituted derivatives: A new route for obtaining of deltanoids

(2010) Dmitry V. Dovbnya et al.   STEROIDS

Microbial transformation of 3β-acetoxypregna-5,16-diene-20-one by Penicillium citrinum

(2010) Jin-Ming Gao et al.   STEROIDS

Characterization of P450 FcpC, the Enzyme Responsible for Bioconversion of Diosgenone to Isonuatigenone in Streptomyces virginiae IBL-14

(2009) W. Wang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Rhodococcus rhodochrous DSM 43269 3-Ketosteroid 9 -Hydroxylase, a Two-Component Iron-Sulfur-Containing Monooxygenase with Subtle Steroid Substrate Specificity

(2009) M. Petrusma et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

7-Ketocholesterol Catabolism by Rhodococcus jostii RHA1

(2009) J. M. Mathieu et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Rapid Screening and Isolation of a Fungus for Sitosterol to Androstenedione Biotransformation

(2009) Alok Malaviya et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Improvement of Steroid Biotransformation with Hydroxypropyl-β-Cyclodextrin Induced Complexation

(2009) Liting Zhang et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Dihydroxylation of dehydroepiandrosterone in positions 7α and 15α by mycelial fungi

(2009) T. G. Lobastova et al.   APPLIED BIOCHEMISTRY AND MICROBIOLOGY

The introduction of the 9α-hydroxy group into androst-4-en-3,17-dione using a new actinobacterium strain

(2009) N. V. Rodina et al.   APPLIED BIOCHEMISTRY AND MICROBIOLOGY

Cholesterol oxidase ChoL is a critical enzyme that catalyzes the conversion of diosgenin to 4-ene-3-keto steroids in Streptomyces virginiae IBL-14

(2009) Bo Li et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Sitosterol bioconversion with resting cells in liquid polymer based systems

(2009) Filipe Carvalho et al.   BIORESOURCE TECHNOLOGY

Microbial cells as catalysts for stereoselective red–ox reactions

(2009) J.D. Carballeira et al.   BIOTECHNOLOGY ADVANCES

New Microbiological Transformations of Steroids byStreptomyces virginiaeIBL-14

(2009) Feng-Qing Wang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Cholesterol oxidase: a model flavoprotein oxidase and a biotechnological tool

(2009) Loredano Pollegioni   FEBS Journal

Cholesterol oxidase: physiological functions

(2009) Joseph Kreit et al.   FEBS Journal

Steroids and neuroprotection: New advances

(2009) Luis M. Garcia-Segura et al.   FRONTIERS IN NEUROENDOCRINOLOGY

A Thiolase of Mycobacterium tuberculosis Is Required for Virulence and Production of Androstenedione and Androstadienedione from Cholesterol

(2009) N. M. Nesbitt et al.   INFECTION AND IMMUNITY

Bendigoles A~C, New Steroids from Gordonia australis Acta 2299

(2009) Kathrin Schneider et al.   JOURNAL OF ANTIBIOTICS

Mycobacterium tuberculosis Is Able To Accumulate and Utilize Cholesterol

(2009) A. Brzostek et al.   JOURNAL OF BACTERIOLOGY

igr Genes and Mycobacterium tuberculosis Cholesterol Metabolism

(2009) J. C. Chang et al.   JOURNAL OF BACTERIOLOGY

Mycobacterial Cytochrome P450 125 (Cyp125) Catalyzes the Terminal Hydroxylation of C27 Steroids

(2009) Jenna K. Capyk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microbial transformation of androst-4-ene-3, 17-dione byBordetellasp. B4CGMCC 2229

(2009) Yanliang Lin et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Effects of hydroxypropyl-β-cyclodextrin on steroids 1-en-dehydrogenation biotransformation by Arthrobacter simplex TCCC 11037

(2009) Min Wang et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Cloning and expression analysis of the duplicated genes for carbon monoxide dehydrogenase of Mycobacterium sp. strain JC1 DSM 3803

(2009) T. Song et al.   MICROBIOLOGY-SGM

Cytochrome P450 125 (CYP125) catalyses C26-hydroxylation to initiate sterol side-chain degradation inRhodococcus jostiiRHA1

(2009) Kamila Z. Rosłoniec et al.   MOLECULAR MICROBIOLOGY

Screening for suitable solvents as substrate carriers for the microbial side-chain cleavage of sitosterol using microtitre plates

(2009) Marco P.C. Marques et al.   PROCESS BIOCHEMISTRY

Studies on Baeyer–Villiger oxidation of steroids: DHEA and pregnenolone d-lactonization pathways in Penicillium camemberti AM83

(2009) Teresa Kołek et al.   STEROIDS

Biotransformations of steroid compounds by Chaetomium sp. KCH 6651

(2009) Tomasz Janeczko et al.   STEROIDS

New oxandrolone derivatives by biotransformation using Rhizopus stolonifer

(2009) M. Iqbal Choudhary et al.   STEROIDS

A new steroidal 5,7-diene derivative, 3β-hydroxyandrosta-5,7-diene-17β-carboxylic acid, shows potent anti-proliferative activity

(2009) Tae-Kang Kim et al.   STEROIDS

New quantification method for estradiol in the prostatic tissues of benign prostatic hyperplasia using liquid chromatography–tandem mass spectrometry

(2009) Seiji Arai et al.   STEROIDS

Sex steroids and the male skeleton: a tale of two hormones

(2009) Filip Callewaert et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Effect of Tween 80 on 9α-steroid hydroxylating activity and ultrastructural characteristics of Rhodococcus sp. cells

(2009) Tatyana Avramova et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Characterization of a Second Rhodococcus erythropolis SQ1 3-Ketosteroid 9 -Hydroxylase Activity Comprising a Terminal Oxygenase Homologue, KshA2, Active with Oxygenase-Reductase Component KshB

(2008) R. van der Geize et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Conversion of 17α-methyltestosterone to methandrostenolone by the bacterium pimelobacter simplex VKPM Ac-1632 with the presence of cyclodextrins

(2008) A. V. Druzhinina et al.   APPLIED BIOCHEMISTRY AND MICROBIOLOGY

Different bacterial strategies to degrade taurocholate

(2008) Verena Rösch et al.   ARCHIVES OF MICROBIOLOGY

3-Keto-5α-steroid Δ1-dehydrogenase fromRhodococcus erythropolisSQ1 and its orthologue inMycobacterium tuberculosisH37Rv are highly specific enzymes that function in cholesterol catabolism

(2008) Jan Knol et al.   BIOCHEMICAL JOURNAL

Androstenedione production by biotransformation of phytosterols

(2008) Alok Malaviya et al.   BIORESOURCE TECHNOLOGY

Microbial transformation of phytosterol in corn flour and soybean flour to 4-androstene-3,17-dione by Fusarium moniliforme Sheld

(2008) Yanliang Lin et al.   BIORESOURCE TECHNOLOGY

Aspects of the steroid response in fungi

(2008) Bronislava Črešnar et al.   CHEMICO-BIOLOGICAL INTERACTIONS

The Actinobacterialmce4Locus Encodes a Steroid Transporter

(2008) William W. Mohn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microbial production of 3-substituted androsta-5,7-diene-17-one

(2008) Dmitry Dovbnya et al.   JOURNAL OF BIOTECHNOLOGY

Dehydrogenation of 11α-hydroxy-16α, 17-epoxyprogesterone by encapsulatedArthrobacter simplexcells in an aqueous/organic solvent two-liquid-phase system

(2008) Jiu-Hong Li et al.   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Enhanced biotransformation of sitosterol to androstenedione by Mycobacterium sp. using cell wall permeabilizing antibiotics

(2008) Alok Malaviya et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Nutrient broth/PEG200/TritonX114/Tween80/Chloroform microemulsion as a reservoir of solubilized sitosterol for biotransformation to androstenedione

(2008) Alok Malaviya et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Whole cell microbial transformation in cloud point system

(2008) Zhilong Wang et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Effect of phase composition on the bioconversion of methyltestosterone in a biphasic system

(2008) Songtao Bie et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Transformation of 3β-hydroxy-5-en-steroids by Mucor racemosus

(2008) Wenzhong Ge et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Biotransformation of 3-keto-androstanes by Gongronella butleri VKM F-1033

(2008) Vjacheslav V. Kollerov et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Kinetic analysis of 11α-hydroxylation of steroids by Rhizopus nigricans

(2008) Haoli Zhou et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Transformation of C19-steroids and testosterone production by sterol-transforming strains of Mycobacterium spp.

(2008) Olga V. Egorova et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Enhancement of 17α-hydroxyprogesterone production from progesterone by biotransformation using hydroxypropyl-β-cyclodextrin complexation technique

(2008) Jiradej Manosroi et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Microbial transformation of testosterone byRhizopus stoloniferandFusarium lini

(2008) Amal Al-Aboudi et al.   NATURAL PRODUCT RESEARCH

Inter-kingdom signalling: communication between bacteria and their hosts

(2008) David T. Hughes et al.   NATURE REVIEWS MICROBIOLOGY

Mycobacterial persistence requires the utilization of host cholesterol

(2008) A. K. Pandey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Baeyer-Villiger oxidation of DHEA, pregnenolone, and androstenedione by Penicillium lilacinum AM111

(2008) Teresa Kołek et al.   STEROIDS

Synthesis of 3β-hydroxy-androsta-5,7-dien-17-one from 3β-hydroxyandrost-5-en-17-one via microbial 7α-hydroxylation

(2008) Tatyana G. Lobastova et al.   STEROIDS

Structural characteristics of anabolic androgenic steroids contributing to binding to the androgen receptor and to their anabolic and androgenic activities

(2008) A.G. Fragkaki et al.   STEROIDS

Microbial transformation of phytosterols mixture from rice bran oil unsaponifiable matter by selected bacteria

(2008) L. A. R. Sallam et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Immobilization of mycobacterial cells onto silicone – Assessing the feasibility of the immobilized biocatalyst in the production of androstenedione from sitosterol

(2007) M.J.C. Claudino et al.   BIORESOURCE TECHNOLOGY

Coexpression of redox partners increases the hydrocortisone (cortisol) production efficiency in CYP11B1 expressing fission yeast Schizosaccharomyces pombe

(2007) Tarek Hakki et al.   JOURNAL OF BIOTECHNOLOGY

Formation of hydroxysteroid derivatives from androst-4-en-3,17-dione by the filamentous fungus Mucor racemosus

(2007) M.A. Faramarzi et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Predominant allylic hydroxylation at carbons 6 and 7 of 4 and 5-ene functionalized steroids by the thermophilic fungus Rhizomucor tauricus IMI23312

(2007) A. Christy Hunter et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Enhancement of androstadienedione production from progesterone by biotransformation using the hydroxypropyl-β-cyclodextrin complexation technique

(2007) Aranya Manosroi et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Metabolism of androst-4-en-3,17-dione by the filamentous fungus Neurospora crassa

(2007) Mohammad Ali Faramarzi et al.   STEROIDS