Targeting the Immune Microenvironment in the Treatment of Head and Neck Squamous Cell Carcinoma
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Targeting the Immune Microenvironment in the Treatment of Head and Neck Squamous Cell Carcinoma
Authors
Keywords
-
Journal
Frontiers in Oncology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2019-10-15
DOI
10.3389/fonc.2019.01084
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- HPV, tumour metabolism and novel target identification in head and neck squamous cell carcinoma
- (2019) Jason C. Fleming et al. BRITISH JOURNAL OF CANCER
- Tumor-associated B cells and humoral immune response in head and neck squamous cell carcinoma
- (2019) Axel Lechner et al. OncoImmunology
- Mechanisms involved in IL-15 superagonist enhancement of anti-PD-L1 therapy
- (2019) Karin M. Knudson et al. Journal for ImmunoTherapy of Cancer
- Regulatory T cells in cancer immunosuppression — implications for anticancer therapy
- (2019) Yosuke Togashi et al. Nature Reviews Clinical Oncology
- The role of regulatory T cells in the response to radiation therapy in head and neck cancer
- (2019) Ayman J Oweida et al. JNCI-Journal of the National Cancer Institute
- Immunotherapy Approaches Beyond PD-1 Inhibition: the Future of Cellular Therapy for Head and Neck Squamous Cell Carcinoma
- (2019) Hannan A. Qureshi et al. CURRENT TREATMENT OPTIONS IN ONCOLOGY
- Inhibition of EphB4-ephrin-B2 signaling reprograms the tumor immune microenvironment in head and neck cancers
- (2019) Shilpa Bhatia et al. CANCER RESEARCH
- Effect of tumor microenvironment on pathogenesis of the head and neck squamous cell carcinoma: a systematic review
- (2019) Barbora Peltanova et al. Molecular Cancer
- The role of extracellular vesicles from different origin in the microenvironment of head and neck cancers
- (2019) Changqing Xie et al. Molecular Cancer
- Cancer-associated fibroblasts as abettors of tumor progression at the crossroads of EMT and therapy resistance
- (2019) Micol Eleonora Fiori et al. Molecular Cancer
- Intralesional interleukin‐2: A novel option to maximize response to systemic immune checkpoint therapy in loco‐regional metastatic melanoma
- (2019) Ewan A. Langan et al. Dermatologic Therapy
- Prognostic significance of CD68+ and CD163+ tumor associated macrophages in head and neck squamous cell carcinoma: A systematic review and meta-analysis
- (2019) Giuseppe Troiano et al. ORAL ONCOLOGY
- Prognostic Significance of Tumor-Associated Macrophage Content in Head and Neck Squamous Cell Carcinoma: A Meta-Analysis
- (2019) Ayan Tyagi Kumar et al. Frontiers in Oncology
- Heterogeneity of the Head and Neck Squamous Cell Carcinoma Immune Landscape and Its Impact on Immunotherapy
- (2019) Madison Canning et al. Frontiers in Cell and Developmental Biology
- Mechanisms of resistance to immune checkpoint inhibitors
- (2018) Russell W Jenkins et al. BRITISH JOURNAL OF CANCER
- Rationale for combination of therapeutic antibodies targeting tumor cells and immune checkpoint receptors: Harnessing innate and adaptive immunity through IgG1 isotype immune effector stimulation
- (2018) Robert L. Ferris et al. CANCER TREATMENT REVIEWS
- Novel effector phenotype of Tim-3+ regulatory T cells leads to enhanced suppressive function in head and neck cancer patients
- (2018) Zhuqing Liu et al. CLINICAL CANCER RESEARCH
- Clinical relevance and suppressive capacity of human MDSC subsets
- (2018) Stephan Lang et al. CLINICAL CANCER RESEARCH
- Tobacco Smoking-Associated Alterations in the Immune Microenvironment of Squamous Cell Carcinomas
- (2018) Alexis Desrichard et al. JNCI-Journal of the National Cancer Institute
- Significance of PD-L1 expression in pulmonary metastases from head and neck squamous cell carcinoma
- (2018) Satoru Okada et al. SURGICAL ONCOLOGY-OXFORD
- The CDK4/6 Inhibitor Abemaciclib Induces a T Cell Inflamed Tumor Microenvironment and Enhances the Efficacy of PD-L1 Checkpoint Blockade
- (2018) David A. Schaer et al. Cell Reports
- Tobacco Smoking-Associated Alterations in the Immune Microenvironment of Squamous Cell Carcinomas
- (2018) Alexis Desrichard et al. JNCI-Journal of the National Cancer Institute
- Combining Immunotherapy and Radiotherapy for Cancer Treatment: Current Challenges and Future Directions
- (2018) Yifan Wang et al. Frontiers in Pharmacology
- Targeting Head and Neck Cancer by Vaccination
- (2018) Chuan Wang et al. Frontiers in Immunology
- Tumor-associated macrophages derived CCL18 promotes metastasis in squamous cell carcinoma of the head and neck
- (2018) Li She et al. Cancer Cell International
- The IL-1/IL-1R axis induces greater fibroblast-derived chemokine release in human papillomavirus-negative compared to positive oropharyngeal cancer
- (2018) Sarmad Al-Sahaf et al. INTERNATIONAL JOURNAL OF CANCER
- Therapeutic human papillomavirus vaccines in head and neck cancer: A systematic review of current clinical trials
- (2018) Katrine Schneider et al. VACCINE
- Immunotherapy combined with epidermal growth factor receptor-tyrosine kinase inhibitors in non-small-cell lung cancer treatment
- (2018) Hongge Liang et al. OncoTargets and Therapy
- Topography of cancer-associated immune cells in human solid tumors
- (2018) Jakob Nikolas Kather et al. eLife
- Combining Immune Checkpoint Blockade and Tumor-Specific Vaccine for Patients With Incurable Human Papillomavirus 16–Related Cancer
- (2018) Erminia Massarelli et al. JAMA Oncology
- Factors Secreted by Cancer-Associated Fibroblasts that Sustain Cancer Stem Properties in Head and Neck Squamous Carcinoma Cells as Potential Therapeutic Targets
- (2018) Saúl Álvarez-Teijeiro et al. Cancers
- 1302TiPCA224-047: A randomized, double-blind, phase II/III study of relatlimab (anti–LAG-3) in combination with nivolumab (anti–PD-1) versus nivolumab alone in previously untreated metastatic or unresectable melanoma
- (2018) E J Lipson et al. ANNALS OF ONCOLOGY
- Reimagining IDO Pathway Inhibition in Cancer Immunotherapy via Downstream Focus on the Tryptophan–Kynurenine–Aryl Hydrocarbon Axis
- (2018) Brian W. Labadie et al. CLINICAL CANCER RESEARCH
- Pan-tumor genomic biomarkers for PD-1 checkpoint blockade–based immunotherapy
- (2018) Razvan Cristescu et al. SCIENCE
- Periostin secreted by cancer-associated fibroblasts promotes cancer stemness in head and neck cancer by activating protein tyrosine kinase 7
- (2018) Binbin Yu et al. Cell Death & Disease
- Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors
- (2017) Frederick Arce Vargas et al. IMMUNITY
- Immunogenic stress and death of cancer cells: Contribution of antigenicity vs adjuvanticity to immunosurveillance
- (2017) Norma Bloy et al. IMMUNOLOGICAL REVIEWS
- PD-L1 Immunohistochemistry Assays for Lung Cancer: Results from Phase 1 of the Blueprint PD-L1 IHC Assay Comparison Project
- (2017) Fred R. Hirsch et al. Journal of Thoracic Oncology
- De-novo and acquired resistance to immune checkpoint targeting
- (2017) Nicholas L Syn et al. LANCET ONCOLOGY
- Tumor Mutational Burden and Response Rate to PD-1 Inhibition
- (2017) Mark Yarchoan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Defining an inflamed tumor immunophenotype in recurrent, metastatic squamous cell carcinoma of the head and neck
- (2017) Glenn J. Hanna et al. ORAL ONCOLOGY
- Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade
- (2017) Dung T. Le et al. SCIENCE
- Human papillomavirus 16 E6 and E7 oncoprotein expression alters microRNA expression in extracellular vesicles
- (2017) Mallory E. Harden et al. VIROLOGY
- Cancer-associated fibroblasts induce metalloprotease-independent cancer cell invasion of the basement membrane
- (2017) Alexandros Glentis et al. Nature Communications
- Crosstalk between tongue carcinoma cells, extracellular vesicles, and immune cells in in vitro and in vivo models
- (2017) Ahmed Al-Samadi et al. Oncotarget
- Tumor-Associated Macrophages Suppress the Cytotoxic Activity of Antimitotic Agents
- (2017) Oakley C. Olson et al. Cell Reports
- Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden
- (2017) Zachary R. Chalmers et al. Genome Medicine
- Myeloid-Derived Suppressor Cells
- (2017) Dmitry I. Gabrilovich Cancer Immunology Research
- Natural Killer Group 2D Ligand Depletion Reconstitutes Natural Killer Cell Immunosurveillance of Head and Neck Squamous Cell Carcinoma
- (2017) Sandra Weil et al. Frontiers in Immunology
- A first-in-human (FIH) study of PF-04518600 (PF-8600) OX40 agonist in adult patients (pts) with select advanced malignancies
- (2016) A. Diab et al. ANNALS OF ONCOLOGY
- A specific, transmembrane interface regulates fibroblast activation protein (FAP) homodimerization, trafficking and exopeptidase activity
- (2016) Benjamaporn Wonganu et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- The Where, the When, and the How of Immune Monitoring for Cancer Immunotherapies in the Era of Checkpoint Inhibition
- (2016) P. S. Hegde et al. CLINICAL CANCER RESEARCH
- First-in-human dose-escalation study of VCN-01, a selective oncolytic adenovirus with hyaluronidase activity in patients with advanced or metastatic cancer
- (2016) M. Hidalgo et al. EUROPEAN JOURNAL OF CANCER
- Resistance Mechanisms to Immune-Checkpoint Blockade in Cancer: Tumor-Intrinsic and -Extrinsic Factors
- (2016) Jonathan M. Pitt et al. IMMUNITY
- Neutrophils in cancer development and progression: Roles, mechanisms, and implications (Review)
- (2016) Xu Zhang et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Antitumor Activity of Pembrolizumab in Biomarker-Unselected Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma: Results From the Phase Ib KEYNOTE-012 Expansion Cohort
- (2016) Laura Q.M. Chow et al. JOURNAL OF CLINICAL ONCOLOGY
- Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma
- (2016) Jesse M. Zaretsky et al. NEW ENGLAND JOURNAL OF MEDICINE
- Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints
- (2016) Shohei Koyama et al. Nature Communications
- Targeted Therapy in Locally Advanced and Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (LA-R/M HNSCC)
- (2016) María Echarri et al. Cancers
- Integrin α3β1 Binding to Fibronectin Is Dependent on the Ninth Type III Repeat
- (2015) Ashley C. Brown et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity
- (2015) Stefani Spranger et al. NATURE
- Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy
- (2015) W. Peng et al. Cancer Discovery
- NK cell-mediated antibody-dependent cellular cytotoxicity in cancer immunotherapy
- (2015) Wei Wang Frontiers in Immunology
- Distinct patterns of intratumoral immune cell infiltrates in patients with HPV-associated compared to non-virally induced head and neck squamous cell carcinoma
- (2015) Simona Partlová et al. OncoImmunology
- Association of macrophages with angiogenesis in oral verrucous and squamous cell carcinomas
- (2015) Dalia H. El-Rouby JOURNAL OF ORAL PATHOLOGY & MEDICINE
- Integrative Analysis of Head and Neck Cancer Identifies Two Biologically Distinct HPV and Three Non-HPV Subtypes
- (2014) M. K. Keck et al. CLINICAL CANCER RESEARCH
- Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines
- (2014) Peter J. Murray et al. IMMUNITY
- Small oral squamous cell carcinomas with nodal lymphogenic metastasis show increased infiltration of M2 polarized macrophages – An immunohistochemical analysis
- (2014) Manuel Weber et al. JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY
- PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation
- (2014) Muhammad Zaeem Noman et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Combination Therapy with Anti–CTLA-4 and Anti–PD-1 Leads to Distinct Immunologic Changes In Vivo
- (2014) Rituparna Das et al. JOURNAL OF IMMUNOLOGY
- Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens
- (2014) Matthew M. Gubin et al. NATURE
- Immune modulation of T-cell and NK (natural killer) cell activities by TEXs (tumour-derived exosomes)
- (2013) Theresa L. Whiteside BIOCHEMICAL SOCIETY TRANSACTIONS
- Intratumoral regulatory T cells upregulate immunosuppressive molecules in head and neck cancer patients
- (2013) H-B Jie et al. BRITISH JOURNAL OF CANCER
- Integrin v 3 and Fibronectin Upregulate Slug in Cancer Cells to Promote Clot Invasion and Metastasis
- (2013) L. M. Knowles et al. CANCER RESEARCH
- Effects of cigarette smoke extract on primary activated T cells
- (2013) Claudia P. Hernandez et al. CELLULAR IMMUNOLOGY
- Enhancement of head and neck squamous cell carcinoma proliferation, invasion, and metastasis by tumor-associated fibroblasts in preclinical models
- (2013) Sarah Elizabeth Wheeler et al. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
- Silencing of human papillomavirus (HPV)E6/E7oncogene expression affects both the contents and the amounts of extracellular microvesicles released from HPV-positive cancer cells
- (2013) Anja Honegger et al. INTERNATIONAL JOURNAL OF CANCER
- Chemotherapy activates cancer-associated fibroblasts to maintain colorectal cancer-initiating cells by IL-17A
- (2013) Fiorenza Lotti et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Carcinoma-associated fibroblasts derive from mesothelial cells via mesothelial-to-mesenchymal transition in peritoneal metastasis
- (2013) Pilar Sandoval et al. JOURNAL OF PATHOLOGY
- M2-polarized tumor-associated macrophages promoted epithelial–mesenchymal transition in pancreatic cancer cells, partially through TLR4/IL-10 signaling pathway
- (2013) Chao-Ying Liu et al. LABORATORY INVESTIGATION
- SOX2 Targets Fibronectin 1 to Promote Cell Migration and Invasion in Ovarian Cancer: New Molecular Leads for Therapeutic Intervention
- (2013) Xiaoyan Lou et al. OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
- Investigation of NK cell function and their modulation in different malignancies
- (2012) Gordana Konjevic et al. IMMUNOLOGIC RESEARCH
- Macrophage plasticity and polarization: in vivo veritas
- (2012) Antonio Sica et al. JOURNAL OF CLINICAL INVESTIGATION
- Macrophage plasticity and polarization in tissue repair and remodelling
- (2012) Alberto Mantovani et al. JOURNAL OF PATHOLOGY
- Immune Suppression in Head and Neck Cancers: A Review
- (2011) Anaëlle Duray et al. Clinical & Developmental Immunology
- Functional mutation analysis of EGFR family genes and corresponding lymph node metastases in head and neck squamous cell carcinoma
- (2011) Takanori Hama et al. CLINICAL & EXPERIMENTAL METASTASIS
- The monocarboxylate transporter family-Role and regulation
- (2011) Andrew P. Halestrap et al. IUBMB LIFE
- Tumour infiltrating CD25+ FoxP3+ regulatory T cells (Tregs) relate to tumour grade and stromal inflammation in oral squamous cell carcinoma
- (2011) Dalal Al-Qahtani et al. JOURNAL OF ORAL PATHOLOGY & MEDICINE
- Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and Treg cells
- (2011) Andrea Facciabene et al. NATURE
- Characterization of Cytokine-Induced Myeloid-Derived Suppressor Cells from Normal Human Peripheral Blood Mononuclear Cells
- (2010) M. G. Lechner et al. JOURNAL OF IMMUNOLOGY
- Fibroblast gene expression profile reflects the stage of tumour progression in oral squamous cell carcinoma
- (2010) Kue Peng Lim et al. JOURNAL OF PATHOLOGY
- Subsets, expansion and activation of myeloid-derived suppressor cells
- (2010) Eliana Ribechini et al. MEDICAL MICROBIOLOGY AND IMMUNOLOGY
- Cancer-associated fibroblasts, a parameter of the tumor microenvironment, overcomes carcinoma-associated parameters in the prognosis of patients with mobile tongue cancer
- (2010) Ibrahim O. Bello et al. ORAL ONCOLOGY
- Polarization of Tumor-Associated Neutrophil Phenotype by TGF-β: “N1” versus “N2” TAN
- (2009) Zvi G. Fridlender et al. CANCER CELL
- Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
- (2009) Kandice R. Levental et al. CELL
- HGF and c-Met Participate in Paracrine Tumorigenic Pathways in Head and Neck Squamous Cell Cancer
- (2009) L. M. Knowles et al. CLINICAL CANCER RESEARCH
- Natural killer cell cytotoxicity: how do they pull the trigger?
- (2009) Nicola J. Topham et al. IMMUNOLOGY
- Mechanism Regulating Reactive Oxygen Species in Tumor-Induced Myeloid-Derived Suppressor Cells
- (2009) C. A. Corzo et al. JOURNAL OF IMMUNOLOGY
- MT1-MMP releases latent TGF-β1 from endothelial cell extracellular matrix via proteolytic processing of LTBP-1
- (2008) O TATTI et al. EXPERIMENTAL CELL RESEARCH
- Recent Advances in Head and Neck Cancer
- (2008) Robert I. Haddad et al. NEW ENGLAND JOURNAL OF MEDICINE
- Platinum-Based Chemotherapy plus Cetuximab in Head and Neck Cancer
- (2008) Jan B. Vermorken et al. NEW ENGLAND JOURNAL OF MEDICINE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now