mTOR/HDAC1 Crosstalk Mediated Suppression of ADH1A and ALDH2 Links Alcohol Metabolism to Hepatocellular Carcinoma Onset and Progression in silico
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Title
mTOR/HDAC1 Crosstalk Mediated Suppression of ADH1A and ALDH2 Links Alcohol Metabolism to Hepatocellular Carcinoma Onset and Progression in silico
Authors
Keywords
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Journal
Frontiers in Oncology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2019-10-04
DOI
10.3389/fonc.2019.01000
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Note: Only part of the references are listed.- Systems biology based meth-miRNA–mRNA regulatory network identifies metabolic imbalance and hyperactive cell cycle signaling involved in hepatocellular carcinoma onset and progression
- (2019) Kashif Rafiq Zahid et al. Cancer Cell International
- Polyol Pathway Links Glucose Metabolism to the Aggressiveness of Cancer Cells
- (2018) Annemarie Schwab et al. CANCER RESEARCH
- Niclosamide Exhibits Potent Anticancer Activity and Synergizes with Sorafenib in Human Renal Cell Cancer Cells
- (2018) Xinyi Yu et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Curcumin: A Natural Pan-HDAC Inhibitor in Cancer
- (2018) Sara Saffar Soflaei et al. CURRENT PHARMACEUTICAL DESIGN
- The mRNA, miRNA and lncRNA networks in hepatocellular carcinoma: An integrative transcriptomic analysis from Gene Expression Omnibus
- (2018) Jian‑Hua Xu et al. Molecular Medicine Reports
- Low glucose metabolism in hepatocellular carcinoma with GPC3 expression
- (2018) You-Cai Li et al. WORLD JOURNAL OF GASTROENTEROLOGY
- The immune contexture of hepatocellular carcinoma predicts clinical outcome
- (2018) Friedrich Foerster et al. Scientific Reports
- Novel tumor suppressor SPRYD4 inhibits tumor progression in hepatocellular carcinoma by inducing apoptotic cell death
- (2018) Kashif Rafiq Zahid et al. CELLULAR ONCOLOGY
- Aberrant Metabolism in Hepatocellular Carcinoma Provides Diagnostic and Therapeutic Opportunities
- (2018) Serena De Matteis et al. Oxidative Medicine and Cellular Longevity
- Altered hepatic genes related to retinol metabolism and plasma retinol in patients with non-alcoholic fatty liver disease
- (2018) Paulina Pettinelli et al. PLoS One
- Computational Discovery of Niclosamide Ethanolamine, a Repurposed Drug Candidate That Reduces Growth of Hepatocellular Carcinoma Cells In Vitro and in Mice by Inhibiting Cell Division Cycle 37 Signaling
- (2017) Bin Chen et al. GASTROENTEROLOGY
- STAT3-mediated upregulation of lncRNA HOXD-AS1 as a ceRNA facilitates liver cancer metastasis by regulating SOX4
- (2017) Hui Wang et al. Molecular Cancer
- Tumor-adjacent tissue co-expression profile analysis reveals pro-oncogenic ribosomal gene signature for prognosis of resectable hepatocellular carcinoma
- (2017) Oleg V. Grinchuk et al. Molecular Oncology
- Integrative analysis of genomic and epigenomic regulation of the transcriptome in liver cancer
- (2017) Hyun Goo Woo et al. Nature Communications
- TIP30 regulates lipid metabolism in hepatocellular carcinoma by regulating SREBP1 through the Akt/mTOR signaling pathway
- (2017) F Yin et al. Oncogenesis
- Integrative Genomic Analysis Identifies the Core Transcriptional Hallmarks of Human Hepatocellular Carcinoma
- (2016) Coralie Allain et al. CANCER RESEARCH
- Bothde novosynthetized and exogenous fatty acids support the growth of hepatocellular carcinoma cells
- (2016) Dan Cao et al. LIVER INTERNATIONAL
- Reprogramming of glucose metabolism in hepatocellular carcinoma: Progress and prospects
- (2016) Run-Ze Shang et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Differentially Expressed miRNAs in Hepatocellular Carcinoma Target Genes in the Genetic Information Processing and Metabolism Pathways
- (2016) Thomas Thurnherr et al. Scientific Reports
- miR-564 acts as a dual inhibitor of PI3K and MAPK signaling networks and inhibits proliferation and invasion in breast cancer
- (2016) Merve Mutlu et al. Scientific Reports
- Neoangiogenesis-related genes are hallmarks of fast-growing hepatocellular carcinomas and worst survival. Results from a prospective study
- (2015) Erica Villa et al. GUT
- Curcumin effectively inhibits oncogenic NF-κB signaling and restrains stemness features in liver cancer
- (2015) Jens U. Marquardt et al. JOURNAL OF HEPATOLOGY
- Severely Impaired and Dysregulated Cytochrome P450 Expression and Activities in Hepatocellular Carcinoma: Implications for Personalized Treatment in Patients
- (2015) T. Yan et al. MOLECULAR CANCER THERAPEUTICS
- Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets
- (2015) Kornelius Schulze et al. NATURE GENETICS
- Amino acid management in cancer
- (2015) Zhi-Yang Tsun et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- PI3K/mTOR mediate mitogen-dependent HDAC1 phosphorylation in breast cancer: a novel regulation of estrogen receptor expression
- (2015) Simona Citro et al. Journal of Molecular Cell Biology
- Activating CAR and β-catenin induces uncontrolled liver growth and tumorigenesis
- (2015) Bingning Dong et al. Nature Communications
- Inhibition of DNA methyltransferase as a novel therapeutic strategy to overcome acquired resistance to dual PI3K/mTOR inhibitors
- (2015) Xiao-jun Qian et al. Oncotarget
- Comprehensive analysis of transcriptome and metabolome analysis in Intrahepatic Cholangiocarcinoma and Hepatocellular Carcinoma
- (2015) Yoshiki Murakami et al. Scientific Reports
- The HDAC Inhibitor Vorinostat Diminishes theIn VitroMetastatic Behavior of Osteosarcoma Cells
- (2015) Xiaodong Mu et al. Biomed Research International
- Viral expression and molecular profiling in liver tissue versus microdissected hepatocytes in hepatitis B virus - associated hepatocellular carcinoma
- (2014) Marta Melis et al. Journal of Translational Medicine
- Sorafenib Metabolism Is Significantly Altered in the Liver Tumor Tissue of Hepatocellular Carcinoma Patient
- (2014) Ling Ye et al. PLoS One
- Methylation Profiles Reveal Distinct Subgroup of Hepatocellular Carcinoma Patients with Poor Prognosis
- (2014) Way-Champ Mah et al. PLoS One
- Genomic Predictors for Recurrence Patterns of Hepatocellular Carcinoma: Model Derivation and Validation
- (2014) Ji Hoon Kim et al. PLOS MEDICINE
- Prediction of Disease-free Survival in Hepatocellular Carcinoma by Gene Expression Profiling
- (2013) Ho-Yeong Lim et al. ANNALS OF SURGICAL ONCOLOGY
- Coffee Reduces Risk for Hepatocellular Carcinoma: An Updated Meta-analysis
- (2013) Francesca Bravi et al. Clinical Gastroenterology and Hepatology
- Diagnostic and Prognostic Molecular Markers in Hepatocellular Carcinoma
- (2013) Beatriz Mínguez et al. DISEASE MARKERS
- Genome-Wide Methylation Analysis and Epigenetic Unmasking Identify Tumor Suppressor Genes in Hepatocellular Carcinoma
- (2013) Kate Revill et al. GASTROENTEROLOGY
- Prognostic Gene Expression Signature for Patients With Hepatitis C–Related Early-Stage Cirrhosis
- (2013) Yujin Hoshida et al. GASTROENTEROLOGY
- Mechanisms of alcohol-induced hepatocellular carcinoma
- (2013) Sreetha Sidharthan et al. Hepatology International
- Targeting the mTOR pathway in hepatocellular carcinoma: Current state and future trends
- (2013) Matthias S. Matter et al. JOURNAL OF HEPATOLOGY
- Correction: Resveratrol as a Pan-HDAC Inhibitor Alters the Acetylation Status of Jistone Proteins in Human-Derived Hepatoblastoma Cells
- (2013) Sascha Venturelli et al. PLoS One
- Carcinoma hepatocelular: epidemiologia, biologia, diagnóstico e terapias
- (2013) Marcos António Gomes et al. Revista da Associacao Medica Brasileira
- Genome-wide DNA methylation profiles in hepatocellular carcinoma
- (2012) Jing Shen et al. HEPATOLOGY
- Structure-Activity Analysis of Niclosamide Reveals Potential Role for Cytoplasmic pH in Control of Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling
- (2012) Bruno D. Fonseca et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- mTOR Inhibitors Synergize on Regression, Reversal of Gene Expression, and Autophagy in Hepatocellular Carcinoma
- (2012) H. E. Thomas et al. Science Translational Medicine
- Definition of the Landscape of Promoter DNA Hypomethylation in Liver Cancer
- (2011) B. Stefanska et al. CANCER RESEARCH
- Activation of mTORC2 by Association with the Ribosome
- (2011) Vittoria Zinzalla et al. CELL
- VEGF gene alternative splicing: pro- and anti-angiogenic isoforms in cancer
- (2011) P. M. Biselli-Chicote et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Gene-expression signature of vascular invasion in hepatocellular carcinoma
- (2011) Beatriz Mínguez et al. JOURNAL OF HEPATOLOGY
- Clinicopathological and prognostic significance of serum and tissue Dickkopf-1 levels in human hepatocellular carcinoma
- (2011) Edmund Kwok-Kwan Tung et al. LIVER INTERNATIONAL
- Mechanisms of mTOR inhibitor resistance in cancer therapy
- (2011) Jennifer S. Carew et al. Targeted Oncology
- Combined Functional Genome Survey of Therapeutic Targets for Hepatocellular Carcinoma
- (2010) R. Satow et al. CLINICAL CANCER RESEARCH
- Gene expression in nontumoral liver tissue and recurrence-free survival in hepatitis C virus-positive hepatocellular carcinoma
- (2010) Masato Tsuchiya et al. Molecular Cancer
- The role of signaling pathways in the development and treatment of hepatocellular carcinoma
- (2010) S Whittaker et al. ONCOGENE
- Molecular Classification and Novel Targets in Hepatocellular Carcinoma: Recent Advancements
- (2010) Yujin Hoshida et al. SEMINARS IN LIVER DISEASE
- A complex interplay between Akt, TSC2 and the two mTOR complexes: Figure 1
- (2009) Jingxiang Huang et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients
- (2009) Balazs Györffy et al. BREAST CANCER RESEARCH AND TREATMENT
- Pivotal Role of mTOR Signaling in Hepatocellular Carcinoma
- (2008) Augusto Villanueva et al. GASTROENTEROLOGY
- Activation of lipogenic pathway correlates with cell proliferation and poor prognosis in hepatocellular carcinoma
- (2008) Taro Yamashita et al. JOURNAL OF HEPATOLOGY
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