Extracellular NK histones promote immune cell anti-tumor activity by inducing cell clusters through binding to CD138 receptor

Dynamic CD138 surface expression regulates switch between myeloma growth and dissemination

(2019) Ilseyar Akhmetzyanova et al.   LEUKEMIA

NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control

(2018) Jan P. Böttcher et al.   CELL

Blockade of the checkpoint receptor TIGIT prevents NK cell exhaustion and elicits potent anti-tumor immunity

(2018) Qing Zhang et al.   NATURE IMMUNOLOGY

Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia

(2018) Shannon L. Maude et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nivolumab plus Ipilimumab in Lung Cancer with a High Tumor Mutational Burden

(2018) Matthew D. Hellmann et al.   NEW ENGLAND JOURNAL OF MEDICINE

CAR T cell immunotherapy for human cancer

(2018) Carl H. June et al.   SCIENCE

Cancer immunotherapy using checkpoint blockade

(2018) Antoni Ribas et al.   SCIENCE

Neuroprotective Activities of Heparin, Heparinase III, and Hyaluronic Acid on the Aβ42-Treated Forebrain Spheroids Derived from Human Stem Cells

(2018) Julie Bejoy et al.   ACS Biomaterials-Science & Engineering

Neuroprotective Activities of Heparin, Heparinase III, and Hyaluronic Acid on the Aβ42-Treated Forebrain Spheroids Derived from Human Stem Cells

(2018) Julie Bejoy et al.   ACS Biomaterials Science & Engineering

Natural Killer Cells: Angels and Devils for Immunotherapy

(2017) Beatriz Martín-Antonio et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cord blood NK cells engineered to express IL-15 and a CD19-targeted CAR show long-term persistence and potent antitumor activity

(2017) E Liu et al.   LEUKEMIA

Multi-cellular natural killer (NK) cell clusters enhance NK cell activation through localizing IL-2 within the cluster

(2017) Miju Kim et al.   Scientific Reports

Natural Killer Cells in the Orchestration of Chronic Inflammatory Diseases

(2017) Luca Parisi et al.   Journal of Immunology Research

Group A Streptococcal M1 Protein Provides Resistance against the Antimicrobial Activity of Histones

(2017) Simon Döhrmann et al.   Scientific Reports

Role of charged lipids in membrane structures — Insight given by simulations

(2016) Sanja Pöyry et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Inflammasome Complexes: Emerging Mechanisms and Effector Functions

(2016) Vijay A.K. Rathinam et al.   CELL

The role of the 14-3-3 protein family in health, disease, and drug development

(2016) Yasaman Aghazadeh et al.   DRUG DISCOVERY TODAY

Extracellular histones, cell-free DNA, or nucleosomes: differences in immunostimulation

(2016) Gerben Marsman et al.   Cell Death & Disease

Neutrophil extracellular traps license macrophages for cytokine production in atherosclerosis

(2015) A. Warnatsch et al.   SCIENCE

Transmissible cytotoxicity of multiple myeloma cells by cord blood-derived NK cells is mediated by vesicle trafficking

(2014) B Martin-Antonio et al.   CELL DEATH AND DIFFERENTIATION

Extracellular histones in tissue injury and inflammation

(2014) Ramanjaneyulu Allam et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Release and activity of histone in diseases

(2014) R Chen et al.   Cell Death & Disease

Controlling Natural Killer Cell Responses: Integration of Signals for Activation and Inhibition

(2013) Eric O. Long et al.   Annual Review of Immunology

Nonanticoagulant heparin prevents histone-mediated cytotoxicity in vitro and improves survival in sepsis

(2013) K. C. A. A. Wildhagen et al.   BLOOD

Heparan sulfate proteoglycan as a cell-surface endocytosis receptor

(2013) Helena C. Christianson et al.   MATRIX BIOLOGY

Antigen Presenting Cell-Mediated Expansion of Human Umbilical Cord Blood Yields Log-Scale Expansion of Natural Killer Cells with Anti-Myeloma Activity

(2013) Nina Shah et al.   PLoS One

From antimicrobial to anticancer peptides. A review

(2013) Diana Gaspar et al.   Frontiers in Microbiology

Novel histone-derived antimicrobial peptides use different antimicrobial mechanisms

(2012) Kathryn E. Pavia et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Antimicrobial properties of arginine- and lysine-rich histones and involvement of bacterial outer membrane protease T in their differential mode of actions

(2011) Chihiro Tagai et al.   PEPTIDES

Innate or Adaptive Immunity? The Example of Natural Killer Cells

(2011) E. Vivier et al.   SCIENCE

Heparan Sulfate Proteoglycans

(2011) S. Sarrazin et al.   Cold Spring Harbor Perspectives in Biology

Trans-SILAC: sorting out the non-cell-autonomous proteome

(2010) Oded Rechavi et al.   NATURE METHODS

NK cells provide helper signal for CD8+ T cells by inducing the expression of membrane-bound IL-15 on DCs

(2009) B. Morandi et al.   INTERNATIONAL IMMUNOLOGY

Syndecan-1 Is Required for Robust Growth, Vascularization, and Metastasis of Myeloma Tumorsin Vivo

(2009) Yekaterina B. Khotskaya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activating receptors promote NK cell expansion for maintenance, IL-10 production, and CD8 T cell regulation during viral infection

(2009) Seung-Hwan Lee et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mechanism of anticancer activity of buforin IIb, a histone H2A-derived peptide

(2008) Hyun Soo Lee et al.   CANCER LETTERS

Regulation of Hierarchical Clustering and Activation of Innate Immune Cells by Dendritic Cells

(2008) Suk-Jo Kang et al.   IMMUNITY