Gene Expression-Based Identification of Antigen-Responsive CD8+ T Cells on a Single-Cell Level

Cell Biology of T Cell Receptor Expression and Regulation

(2018) Andrés Alcover et al.   Annual Review of Immunology

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Long-Term Persistence of Exhausted CD8 T Cells in Chronic Infection Is Regulated by MicroRNA-155

(2018) Erietta Stelekati et al.   Cell Reports

Optimized Peptide–MHC Multimer Protocols for Detection and Isolation of Autoimmune T-Cells

(2018) Garry Dolton et al.   Frontiers in Immunology

Conventional and Neo-Antigenic Peptides Presented by β Cells Are Targeted by Circulating Naïve CD8+ T Cells in Type 1 Diabetic and Healthy Donors

(2018) Sergio Gonzalez-Duque et al.   Cell Metabolism

Development of T cell lines sensitive to antigen stimulation

(2018) Theodore Williams et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Cutting Edge: Transcriptional Profiling Reveals Multifunctional and Cytotoxic Antiviral Responses of Zika Virus–Specific CD8+ T Cells

(2018) Alba Grifoni et al.   JOURNAL OF IMMUNOLOGY

A Highly Active Form of XCL1/Lymphotactin Functions as an Effective Adjuvant to Recruit Cross-Presenting Dendritic Cells for Induction of Effector and Memory CD8+ T Cells

(2018) Kazuhiko Matsuo et al.   Frontiers in Immunology

CD8 + T Cells Orchestrate pDC-XCR1 + Dendritic Cell Spatial and Functional Cooperativity to Optimize Priming

(2017) Anna Brewitz et al.   IMMUNITY

Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation

(2017) Tizong Miao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Quantifiable predictive features define epitope-specific T cell receptor repertoires

(2017) Pradyot Dash et al.   NATURE

Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism

(2017) Youdong Pan et al.   NATURE

Identifying specificity groups in the T cell receptor repertoire

(2017) Jacob Glanville et al.   NATURE

CD8+ T cells specific for the islet autoantigen IGRP are restricted in their T cell receptor chain usage

(2017) Yannick F. Fuchs et al.   Scientific Reports

T cell fate and clonality inference from single-cell transcriptomes

(2016) Michael J T Stubbington et al.   NATURE METHODS

Molecular basis for universal HLA-A*0201–restricted CD8+T-cell immunity against influenza viruses

(2016) Sophie A. Valkenburg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vagaries of the ELISpot assay: Specific detection of antigen responsive cells requires purified CD8+ T cells and MHC class I expressing antigen presenting cell lines

(2015) Yannick F. Fuchs et al.   CLINICAL IMMUNOLOGY

Effects of High-Dose Oral Insulin on Immune Responses in Children at High Risk for Type 1 Diabetes

(2015) Ezio Bonifacio et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Combinatorial labeling of single cells for gene expression cytometry

(2015) H. C. Fan et al.   SCIENCE

Multiple Glycines in TCR  -Chains Determine Clonally Diverse Nature of Human T Cell Memory to Influenza A Virus

(2014) Y. N. Naumov et al.   JOURNAL OF IMMUNOLOGY

Bayesian approach to single-cell differential expression analysis

(2014) Peter V Kharchenko et al.   NATURE METHODS

Full-length RNA-seq from single cells using Smart-seq2

(2014) Simone Picelli et al.   Nature Protocols

EGR2 is critical for peripheral naïve T-cell differentiation and the T-cell response to influenza

(2014) Ning Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modeling Bi-modality Improves Characterization of Cell Cycle on Gene Expression in Single Cells

(2014) Andrew McDavid et al.   PLoS Computational Biology

MicroRNA-155 Is Required for Effector CD8+ T Cell Responses to Virus Infection and Cancer

(2013) Jan C. Dudda et al.   IMMUNITY

Rapid effector function of memory CD8+ T cells requires an immediate-early glycolytic switch

(2013) Patrick M Gubser et al.   NATURE IMMUNOLOGY

Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients

(2012) Ken T. Coppieters et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Parallel detection of antigen-specific T cell responses by combinatorial encoding of MHC multimers

(2012) Rikke Sick Andersen et al.   Nature Protocols

Islet-Specific CTL Cloned from a Type 1 Diabetes Patient Cause Beta-Cell Destruction after Engraftment into HLA-A2 Transgenic NOD/SCID/IL2RG Null Mice

(2012) Wendy W. J. Unger et al.   PLoS One

Discovery of low-affinity preproinsulin epitopes and detection of autoreactive CD8 T-cells using combinatorial MHC multimers

(2011) Wendy W. Unger et al.   JOURNAL OF AUTOIMMUNITY

CRTAM Confers Late-Stage Activation of CD8+ T Cells to Regulate Retention within Lymph Node

(2009) A. Takeuchi et al.   JOURNAL OF IMMUNOLOGY

Parallel detection of antigen-specific T-cell responses by multidimensional encoding of MHC multimers

(2009) Sine Reker Hadrup et al.   NATURE METHODS

Comparative analysis of transcriptional profiling of CD3+, CD4+ and CD8+ T cells identifies novel immune response players in T-Cell activation

(2008) Min Wang et al.   BMC GENOMICS

Rapid identification and sorting of viable virus-reactive CD4+ and CD8+ T cells based on antigen-triggered CD137 expression

(2008) Thomas C. Wehler et al.   JOURNAL OF IMMUNOLOGICAL METHODS