CD8+ T cells specific for the islet autoantigen IGRP are restricted in their T cell receptor chain usage

Abundant cytomegalovirus (CMV) reactive clonotypes in the CD8+T cell receptor alpha repertoire following allogeneic transplantation

(2016) C. S. Link et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity

(2016) David K. Cole et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular basis for universal HLA-A*0201–restricted CD8+T-cell immunity against influenza viruses

(2016) Sophie A. Valkenburg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

αβ T cell receptors as predictors of health and disease

(2015) Meriem Attaf et al.   Cellular & Molecular Immunology

Vagaries of the ELISpot assay: Specific detection of antigen responsive cells requires purified CD8+ T cells and MHC class I expressing antigen presenting cell lines

(2015) Yannick F. Fuchs et al.   CLINICAL IMMUNOLOGY

Naive CD8+ T-cell precursors display structured TCR repertoires and composite antigen-driven selection dynamics

(2015) Michelle A Neller et al.   IMMUNOLOGY AND CELL BIOLOGY

High Diversity in the TCR Repertoire of GAD65 Autoantigen-Specific Human CD4+T Cells

(2015) Anne Eugster et al.   JOURNAL OF IMMUNOLOGY

Narrowing of Human Influenza A Virus-Specific T Cell Receptor α and β Repertoires with Increasing Age

(2015) Anna Gil et al.   JOURNAL OF VIROLOGY

Indoctrinating T cells to attack pathogens through homeschooling

(2015) Caitlin S. Parello et al.   TRENDS IN IMMUNOLOGY

Proinsulin-Specific, HLA-DQ8, and HLA-DQ8-Transdimer–Restricted CD4+T Cells Infiltrate Islets in Type 1 Diabetes

(2014) Vimukthi Pathiraja et al.   DIABETES

β-Cell–Specific CD8 T Cell Phenotype in Type 1 Diabetes Reflects Chronic Autoantigen Exposure

(2014) Ania Skowera et al.   DIABETES

Functional cytotoxic T lymphocytes against IGRP206-214 predict diabetes in the non-obese diabetic mouse

(2014) Hyun-Ja Ko et al.   IMMUNOLOGY AND CELL BIOLOGY

Multiple Glycines in TCR  -Chains Determine Clonally Diverse Nature of Human T Cell Memory to Influenza A Virus

(2014) Y. N. Naumov et al.   JOURNAL OF IMMUNOLOGY

Measuring T cell receptor and T cell gene expression diversity in antigen-responsive human CD4+ T cells

(2013) Anne Eugster et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Preparing Unbiased T-Cell Receptor and Antibody cDNA Libraries for the Deep Next Generation Sequencing Profiling

(2013) Ilgar Z. Mamedov et al.   Frontiers in Immunology

ZnT8 Is a Major CD8+ T Cell-Recognized Autoantigen in Pediatric Type 1 Diabetes

(2012) E. Enee et al.   DIABETES

T-cell receptor repertoire analysis in monozygotic twins concordant and discordant for type 1 diabetes

(2012) Claudio Fozza et al.   IMMUNOBIOLOGY

Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients

(2012) Ken T. Coppieters et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Islet-Specific CTL Cloned from a Type 1 Diabetes Patient Cause Beta-Cell Destruction after Engraftment into HLA-A2 Transgenic NOD/SCID/IL2RG Null Mice

(2012) Wendy W. J. Unger et al.   PLoS One

Deletion of the G6pc2 Gene Encoding the Islet-Specific Glucose-6-Phosphatase Catalytic Subunit–Related Protein Does Not Affect the Progression or Incidence of Type 1 Diabetes in NOD/ShiLtJ Mice

(2011) James K. Oeser et al.   DIABETES

A Single Autoimmune T Cell Receptor Recognizes More Than a Million Different Peptides

(2011) Linda Wooldridge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Current approaches to measuring human islet-antigen specific T cell function in type 1 diabetes

(2010) S. I. Mannering et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Simultaneous Detection of Circulating Autoreactive CD8+ T-Cells Specific for Different Islet Cell-Associated Epitopes Using Combinatorial MHC Multimers

(2010) J. H. Velthuis et al.   DIABETES

Identification of a public CDR3 motif and a biased utilization of T-cell receptor V beta and J beta chains in HLA-A2/Melan-A-specific T-cell clonotypes of melanoma patients

(2009) Federico Serana et al.   Journal of Translational Medicine

Identification of novel IGRP epitopes targeted in type 1 diabetes patients

(2008) Irene Jarchum et al.   CLINICAL IMMUNOLOGY

The Frequency and Immunodominance of Islet-Specific CD8+ T-cell Responses Change after Type 1 Diabetes Diagnosis and Treatment

(2008) E. Martinuzzi et al.   DIABETES

IMGT(R), the international ImMunoGeneTics information system(R)

(2008) M.-P. Lefranc et al.   NUCLEIC ACIDS RESEARCH