Choroidal Neovascularization: Mechanisms of Endothelial Dysfunction
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Title
Choroidal Neovascularization: Mechanisms of Endothelial Dysfunction
Authors
Keywords
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Journal
Frontiers in Pharmacology
Volume 10, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2019-11-29
DOI
10.3389/fphar.2019.01363
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Note: Only part of the references are listed.- Human blood vessel organoids as a model of diabetic vasculopathy
- (2019) Reiner A. Wimmer et al. NATURE
- Blood–brain barrier breakdown is an early biomarker of human cognitive dysfunction
- (2019) Daniel A. Nation et al. NATURE MEDICINE
- Intravenous treatment of choroidal neovascularization by photo-targeted nanoparticles
- (2019) Yanfei Wang et al. Nature Communications
- Comorbidity of dementia and age-related macular degeneration calls for clinical awareness: a meta-analysis
- (2019) Shi Song Rong et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- Efficacy of simultaneous VEGF‐A/ANG‐2 neutralization in suppressing spontaneous choroidal neovascularization
- (2019) Richard H Foxton et al. EMBO Molecular Medicine
- Anti‐VEGF‐A/ANG2 combotherapy limits pathological angiogenesis in the eye: a replication study
- (2019) Anne Wolf et al. EMBO Molecular Medicine
- Genomics institute to close world-leading animal facility
- (2019) Holly Else NATURE
- Nitrosative stress drives heart failure with preserved ejection fraction
- (2019) Gabriele G. Schiattarella et al. NATURE
- Amyloid β oligomers constrict human capillaries in Alzheimer’s disease via signaling to pericytes
- (2019) Ross Nortley et al. SCIENCE
- Models of retinal diseases and their applicability in drug discovery
- (2018) Goldis Malek et al. Expert Opinion on Drug Discovery
- Clinical pharmacology of intravitreal anti-VEGF drugs
- (2018) Stefano Fogli et al. EYE
- Cellular regeneration strategies for macular degeneration: past, present and future
- (2018) Valeria Chichagova et al. EYE
- Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders
- (2018) Melanie D. Sweeney et al. Nature Reviews Neurology
- Baseline Predictors of Visual Acuity Outcome in Patients with Wet Age-Related Macular Degeneration
- (2018) Xinyuan Zhang et al. Biomed Research International
- The Use of Vascular Endothelial Growth Factor Inhibitors and Complementary Treatment Options in Polypoidal Choroidal Vasculopathy: A Subtype of Neovascular Age-Related Macular Degeneration
- (2018) Kelvin Teo et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- PGC-1α Protects RPE Cells of the Aging Retina against Oxidative Stress-Induced Degeneration through the Regulation of Senescence and Mitochondrial Quality Control. The Significance for AMD Pathogenesis
- (2018) Kai Kaarniranta et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Age-Related Macular Degeneration (AMD): Alzheimer's Disease in the Eye?
- (2018) Kai Kaarniranta et al. JOURNAL OF ALZHEIMERS DISEASE
- Lessons from Recent Phase III Trial Failures: Don't Design Phase III Trials Based on Retrospective Subgroup Analyses from Phase II Trials
- (2018) Philip J. Rosenfeld et al. OPHTHALMOLOGY
- Complement System and Age-Related Macular Degeneration: Implications of Gene-Environment Interaction for Preventive and Personalized Medicine
- (2018) Andrea Maugeri et al. Biomed Research International
- Associations between recent and established ophthalmic conditions and risk of Alzheimer's disease
- (2018) Cecilia S. Lee et al. Alzheimers & Dementia
- Association between genetic variation of complement C3 and the susceptibility to advanced age-related macular degeneration: a meta-analysis
- (2018) Jun Zhang et al. BMC Ophthalmology
- Generation of an immortalized human choroid endothelial cell line (iChEC-1) using an endothelial cell specific promoter
- (2018) Joseph C. Giacalone et al. MICROVASCULAR RESEARCH
- Polypoidal choroidal vasculopathy treatment options: A meta-analysis
- (2017) Tianwei Qian et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- Induced pluripotent stem cell-based therapy for age-related macular degeneration
- (2017) Peter Bracha et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- OCT angiography documented reperfusion of translocated autologous full thickness RPE-choroid graft for complicated neovascular age-related macular degeneration
- (2017) M Veckeneer et al. EYE
- Combined VEGF and PDGF inhibition for neovascular AMD: anti-angiogenic properties of axitinib on human endothelial cells and pericytes in vitro
- (2017) Jakob Siedlecki et al. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
- Association Between Midlife Vascular Risk Factors and Estimated Brain Amyloid Deposition
- (2017) Rebecca F. Gottesman et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Cerebral blood flow regulation and neurovascular dysfunction in Alzheimer disease
- (2017) Kassandra Kisler et al. NATURE REVIEWS NEUROSCIENCE
- Dual Antagonism of PDGF and VEGF in Neovascular Age-Related Macular Degeneration
- (2017) Glenn J. Jaffe et al. OPHTHALMOLOGY
- TGF-β participates choroid neovascularization through Smad2/3-VEGF/TNF-α signaling in mice with Laser-induced wet age-related macular degeneration
- (2017) Xiaolei Wang et al. Scientific Reports
- Elevated angiopoietin 2 in aqueous of patients with neovascular age related macular degeneration correlates with disease severity at presentation
- (2017) Danny S. Ng et al. Scientific Reports
- Connective Tissue Growth Factor Promotes Efficient Generation of Human Induced Pluripotent Stem Cell-Derived Choroidal Endothelium
- (2017) Allison E. Songstad et al. Stem Cells Translational Medicine
- An Overview of the Fovista and Rinucumab Trials and the Fate of Anti-PDGF Medications
- (2017) Evan N. Dunn et al. Ophthalmic Surgery Lasers & Imaging Retina
- Bone marrow-derived cells in ocular neovascularization: contribution and mechanisms
- (2016) Fan Gao et al. ANGIOGENESIS
- Targeting the complement system for the management of retinal inflammatory and degenerative diseases
- (2016) Heping Xu et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Selective accumulation of the complement membrane attack complex in aging choriocapillaris
- (2016) Kathleen R. Chirco et al. EXPERIMENTAL EYE RESEARCH
- Structural and molecular changes in the aging choroid: implications for age-related macular degeneration
- (2016) K R Chirco et al. EYE
- Relation of cerebral vessel disease to Alzheimer's disease dementia and cognitive function in elderly people: a cross-sectional study
- (2016) Zoe Arvanitakis et al. LANCET NEUROLOGY
- A missense variant in FGD6 confers increased risk of polypoidal choroidal vasculopathy
- (2016) Lulin Huang et al. NATURE GENETICS
- Neurovascular unit impairment in early Alzheimer's disease measured with magnetic resonance imaging
- (2016) Harm J. van de Haar et al. NEUROBIOLOGY OF AGING
- Age-related macular degeneration and polypoidal choroidal vasculopathy in Asians
- (2016) Chee Wai Wong et al. PROGRESS IN RETINAL AND EYE RESEARCH
- GENETIC FACTORS ASSOCIATED WITH CHOROIDAL VASCULAR HYPERPERMEABILITY AND SUBFOVEAL CHOROIDAL THICKNESS IN POLYPOIDAL CHOROIDAL VASCULOPATHY
- (2016) Seigo Yoneyama et al. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
- DISTINGUISHING POLYPOIDAL CHOROIDAL VASCULOPATHY FROM TYPICAL NEOVASCULAR AGE-RELATED MACULAR DEGENERATION BASED ON SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY
- (2016) Ran Liu et al. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
- Treatment of polypoidal choroidal vasculopathy by photodynamic therapy, aflibercept and dexamethasone triple therapy
- (2016) Mary Ho et al. Scientific Reports
- Histopathological Insights Into Choroidal Vascular Loss in Clinically Documented Cases of Age-Related Macular Degeneration
- (2016) Johanna M. Seddon et al. JAMA Ophthalmology
- The Eye As a Biomarker for Alzheimer's Disease
- (2016) Jeremiah K. H. Lim et al. Frontiers in Neuroscience
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- (2016) Mariela C. Marazita et al. Redox Biology
- Vascular contributions to cognitive impairment and dementia including Alzheimer's disease
- (2015) Heather M. Snyder et al. Alzheimers & Dementia
- Dementia of the eye: the role of amyloid beta in retinal degeneration
- (2015) J A Ratnayaka et al. EYE
- New loci and coding variants confer risk for age-related macular degeneration in East Asians
- (2015) Ching-Yu Cheng et al. Nature Communications
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- (2015) Yan Gong et al. PLoS One
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- (2014) Yi Yu et al. HUMAN MOLECULAR GENETICS
- Is age-related macular degeneration a manifestation of systemic disease? New prospects for early intervention and treatment
- (2014) C. M. G. Cheung et al. JOURNAL OF INTERNAL MEDICINE
- Choriocapillaris breakdown precedes retinal degeneration in age-related macular degeneration
- (2014) Antje Biesemeier et al. NEUROBIOLOGY OF AGING
- Genes in the High-Density Lipoprotein Metabolic Pathway in Age-related Macular Degeneration and Polypoidal Choroidal Vasculopathy
- (2014) Ke Liu et al. OPHTHALMOLOGY
- Age-Related Macular Degeneration and the Incidence of Cardiovascular Disease: A Systematic Review and Meta-Analysis
- (2014) Juan Wu et al. PLoS One
- Hyperhomocysteinemia in Patients with Polypoidal Choroidal Vasculopathy: A Case Control Study
- (2014) Hui-Chen Cheng et al. PLoS One
- ASSOCIATIONS BETWEEN CARDIOVASCULAR RISK FACTORS AND EARLY AGE-RELATED MACULAR DEGENERATION IN A RURAL CHINESE ADULT POPULATION
- (2014) Ke Yang et al. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
- Current Treatment Limitations in Age-Related Macular Degeneration and Future Approaches Based on Cell Therapy and Tissue Engineering
- (2014) P. Fernández-Robredo et al. Journal of Ophthalmology
- Markers of Inflammation, Oxidative Stress, and Endothelial Dysfunction and the 20-Year Cumulative Incidence of Early Age-Related Macular Degeneration
- (2014) Ronald Klein et al. JAMA Ophthalmology
- Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis
- (2014) Wan Ling Wong et al. Lancet Global Health
- Increased Risk of Parkinson Disease Following a Diagnosis of Neovascular Age-Related Macular Degeneration: A Retrospective Cohort Study
- (2013) Shiu-Dong Chung et al. AMERICAN JOURNAL OF OPHTHALMOLOGY
- Non-responders to treatment with antagonists of vascular endothelial growth factor in age-related macular degeneration
- (2013) Ilse Krebs et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- HtrA1 is induced by oxidative stress and enhances cell senescence through p38 MAPK pathway
- (2013) Supanji et al. EXPERIMENTAL EYE RESEARCH
- Tissue-Specific Host Recognition by Complement Factor H Is Mediated by Differential Activities of Its Glycosaminoglycan-Binding Regions
- (2013) S. J. Clark et al. JOURNAL OF IMMUNOLOGY
- Seven new loci associated with age-related macular degeneration
- (2013) Lars G Fritsche et al. NATURE GENETICS
- The Relationship of Atherosclerosis to the 10-Year Cumulative Incidence of Age-related Macular Degeneration: The Beaver Dam Studies
- (2013) Ronald Klein et al. OPHTHALMOLOGY
- Seven-Year Outcomes in Ranibizumab-Treated Patients in ANCHOR, MARINA, and HORIZON
- (2013) Soraya Rofagha et al. OPHTHALMOLOGY
- NLRP3 Inflammasome Blockade Inhibits VEGF-A-Induced Age-Related Macular Degeneration
- (2013) Alexander G. Marneros Cell Reports
- Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab
- (2012) Nicholas Papadopoulos et al. ANGIOGENESIS
- Endothelial dysfunction : the early predictor of atherosclerosis
- (2012) Mashudu Mudau et al. Cardiovascular Journal of Africa
- Hypoxia Specific SDF-1 Expression by Retinal Pigment Epithelium Initiates Bone Marrow-derived Cells to Participate in Choroidal Neovascularization in a Laser-induced Mouse Model
- (2012) Zhao-Xia Zhang et al. CURRENT EYE RESEARCH
- Preferred therapies for neovascular age-related macular degeneration
- (2012) David R. Lally et al. CURRENT OPINION IN OPHTHALMOLOGY
- Targeted deletion of Vegfa in adult mice induces vision loss
- (2012) Toshihide Kurihara et al. JOURNAL OF CLINICAL INVESTIGATION
- Animal models of age related macular degeneration
- (2012) Mark E. Pennesi et al. MOLECULAR ASPECTS OF MEDICINE
- Understanding age-related macular degeneration (AMD): Relationships between the photoreceptor/retinal pigment epithelium/Bruch’s membrane/choriocapillaris complex
- (2012) Imran Bhutto et al. MOLECULAR ASPECTS OF MEDICINE
- The retina as a window to the brain—from eye research to CNS disorders
- (2012) Anat London et al. Nature Reviews Neurology
- HORIZON: An Open-Label Extension Trial of Ranibizumab for Choroidal Neovascularization Secondary to Age-Related Macular Degeneration
- (2012) Michael A. Singer et al. OPHTHALMOLOGY
- The SECURE Study
- (2012) Rufino Silva et al. OPHTHALMOLOGY
- Overexpression of HTRA1 Leads to Down-Regulation of Fibronectin and Functional Changes in RF/6A Cells and HUVECs
- (2012) Jingjing Jiang et al. PLoS One
- ENGORGEMENT OF VORTEX VEIN AND POLYPOIDAL CHOROIDAL VASCULOPATHY
- (2012) Song Ee Chung et al. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
- Mechanisms Involved in the Aging-Induced Vascular Dysfunction
- (2012) Mariam El Assar et al. Frontiers in Physiology
- Complement system activation and endothelial dysfunction in patients with age-related macular degeneration (AMD): possible relationship between AMD and atherosclerosis
- (2011) Anna Machalińska et al. ACTA OPHTHALMOLOGICA
- Development and Expression of Amyloid-β Peptide 42 in Retinal Ganglion Cells in Rats
- (2011) Jianqiang Wang et al. Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology
- Vascular endothelial growth factors in retinal and choroidal neovascular diseases
- (2011) Kati Kinnunen et al. ANNALS OF MEDICINE
- Bone marrow-derived cells serve as proangiogenic macrophages but not endothelial cells in wound healing
- (2011) Y. Okuno et al. BLOOD
- Pericytes promote endothelial cell survival through induction of autocrine VEGF-A signaling and Bcl-w expression
- (2011) M. Franco et al. BLOOD
- Global estimates of visual impairment: 2010
- (2011) Donatella Pascolini et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- Identification and characterization of a resident vascular stem/progenitor cell population in preexisting blood vessels
- (2011) Hisamichi Naito et al. EMBO JOURNAL
- Intravitreal bevacizumab and ranibizumab injections for patients with polypoidal choroidal vasculopathy
- (2011) H J Cho et al. EYE
- Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration
- (2011) Yi Yu et al. HUMAN MOLECULAR GENETICS
- Age-related macular degeneration and the complement system
- (2011) S. Khandhadia et al. IMMUNOBIOLOGY
- High Temperature Requirement Factor A1 (HTRA1) Gene Regulates Angiogenesis through Transforming Growth Factor-β Family Member Growth Differentiation Factor 6
- (2011) Li Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Complement factor H binds malondialdehyde epitopes and protects from oxidative stress
- (2011) David Weismann et al. NATURE
- The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics
- (2011) Eric Karran et al. NATURE REVIEWS DRUG DISCOVERY
- Ranibizumab and Bevacizumab for Neovascular Age-Related Macular Degeneration
- (2011) NEW ENGLAND JOURNAL OF MEDICINE
- Overexpression of HTRA1 Leads to Ultrastructural Changes in the Elastic Layer of Bruch's Membrane via Cleavage of Extracellular Matrix Components
- (2011) Sarah Vierkotten et al. PLoS One
- Increased expression of multifunctional serine protease, HTRA1, in retinal pigment epithelium induces polypoidal choroidal vasculopathy in mice
- (2011) A. Jones et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Parallel findings in age-related macular degeneration and Alzheimer’s disease
- (2011) Kyoko Ohno-Matsui PROGRESS IN RETINAL AND EYE RESEARCH
- THE ASSOCIATION BETWEEN DRUSEN EXTENT AND FOVEOLAR CHOROIDAL BLOOD FLOW IN AGE-RELATED MACULAR DEGENERATION
- (2011) Thomas L Berenberg et al. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
- Treatment of polypoidal choroidal vasculopathy by intravitreal injection of bevacizumab
- (2010) Akitaka Tsujikawa et al. JAPANESE JOURNAL OF OPHTHALMOLOGY
- Impaired Binding of the Age-related Macular Degeneration-associated Complement Factor H 402H Allotype to Bruch's Membrane in Human Retina
- (2010) Simon J. Clark et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Viewing Ageing Eyes: Diverse Sites of Amyloid Beta Accumulation in the Ageing Mouse Retina and the Up-Regulation of Macrophages
- (2010) Jaimie Hoh Kam et al. PLoS One
- Animal models of choroidal and retinal neovascularization
- (2010) Hans E. Grossniklaus et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Amyloid precursor protein processing and retinal pathology in mouse models of Alzheimer’s disease
- (2009) R. Michael Dutescu et al. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
- Complement and immune defense: From innate immunity to human diseases
- (2009) Peter F. Zipfel IMMUNOLOGY LETTERS
- Oxidative stress promotes ocular neovascularization
- (2009) Aling Dong et al. JOURNAL OF CELLULAR PHYSIOLOGY
- The Binding of Factor H to a Complex of Physiological Polyanions and C3b on Cells Is Impaired in Atypical Hemolytic Uremic Syndrome
- (2009) V. P. Ferreira et al. JOURNAL OF IMMUNOLOGY
- Associations Between Chronic Kidney Disease and Age-Related Macular Degeneration
- (2009) Dorothea Nitsch et al. OPHTHALMIC EPIDEMIOLOGY
- Intravitreal bevacizumab (Avastin) with or without photodynamic therapy for the treatment of polypoidal choroidal vasculopathy
- (2008) T Y Y Lai et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- Age-related macular degeneration and mortality from cardiovascular disease or stroke
- (2008) J S L Tan et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- Endothelin-1, aging and hypertension
- (2008) Brian L Stauffer et al. CURRENT OPINION IN CARDIOLOGY
- Age-related ocular vascular changes
- (2008) Rita Ehrlich et al. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
- Photodynamic therapy for polypoidal choroidal vasculopathy: Vaso-occlusive effect on the branching vascular network and origin of recurrence
- (2008) Won Ki Lee et al. JAPANESE JOURNAL OF OPHTHALMOLOGY
- Long-term effects of Aβ42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial
- (2008) Clive Holmes et al. LANCET
- Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability
- (2008) Christopher A Jones et al. NATURE MEDICINE
- Oxidative damage–induced inflammation initiates age-related macular degeneration
- (2008) Joe G Hollyfield et al. NATURE MEDICINE
- Age-Related Macular Degeneration
- (2008) Rama D. Jager et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cardiovascular Disease and Hypertension Are Strong Risk Factors for Choroidal Neovascularization
- (2008) Ruth E. Hogg et al. OPHTHALMOLOGY
- Bone marrow-derived circulating endothelial precursors do not contribute to vascular endothelium and are not needed for tumor growth
- (2008) S. Purhonen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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