Internalized GPCRs as Potential Therapeutic Targets for the Management of Pain
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Internalized GPCRs as Potential Therapeutic Targets for the Management of Pain
Authors
Keywords
-
Journal
Frontiers in Molecular Neuroscience
Volume 12, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2019-11-12
DOI
10.3389/fnmol.2019.00273
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- New Trends in Migraine Pharmacology: Targeting Calcitonin Gene–Related Peptide (CGRP) With Monoclonal Antibodies
- (2019) Damiana Scuteri et al. Frontiers in Pharmacology
- Associations between gabapentinoids and suicidal behaviour, unintentional overdoses, injuries, road traffic incidents, and violent crime: population based cohort study in Sweden
- (2019) Yasmina Molero et al. BMJ-British Medical Journal
- Regulation of noradrenergic and serotonergic systems by cannabinoids: relevance to cannabinoid-induced effects
- (2018) Aitziber Mendiguren et al. LIFE SCIENCES
- A Genetically Encoded Biosensor Reveals Location Bias of Opioid Drug Action
- (2018) Miriam Stoeber et al. NEURON
- Analgesic Effects of A Novel Ph-Dependent μ-Opioid Receptor Agonist in Models of Neuropathic and Abdominal Pain
- (2018) Antonio Rodriguez-Gaztelumendi et al. PAIN
- Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome
- (2018) Nestor N. Jimenez-Vargas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genetically Encoded FRET Biosensors to Illuminate Compartmentalised GPCR Signalling
- (2018) Michelle L. Halls et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Gabapentinoid Use in the United States 2002 Through 2015
- (2018) Michael E. Johansen JAMA Internal Medicine
- Therapeutic Targeting of Endosomal G-Protein-Coupled Receptors
- (2018) Alex R.B. Thomsen et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- New Data on Opioid Use and Prescribing in the United States
- (2017) Anne Schuchat et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Functional selectivity of GPCR-directed drug action through location bias
- (2017) Roshanak Irannejad et al. Nature Chemical Biology
- Trends in GPCR drug discovery: new agents, targets and indications
- (2017) Alexander S. Hauser et al. NATURE REVIEWS DRUG DISCOVERY
- Gabapentin and Pregabalin for Pain — Is Increased Prescribing a Cause for Concern?
- (2017) Christopher W. Goodman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Spinal intracellular metabotropic glutamate receptor 5 (mGluR5) contributes to pain and c-fos expression in a rat model of inflammatory pain
- (2017) Kathleen Vincent et al. PAIN
- Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission
- (2017) Rebecca E. Yarwood et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A nontoxic pain killer designed by modeling of pathological receptor conformations
- (2017) V. Spahn et al. SCIENCE
- Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief
- (2017) Dane D. Jensen et al. Science Translational Medicine
- GPCR Dynamics: Structures in Motion
- (2016) Naomi R. Latorraca et al. CHEMICAL REVIEWS
- CDC Guideline for Prescribing Opioids for Chronic Pain—United States, 2016
- (2016) Deborah Dowell et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Antidepressants and gabapentinoids in neuropathic pain: Mechanistic insights
- (2016) Mélanie Kremer et al. NEUROSCIENCE
- Plasma membrane localization of the μ-opioid receptor controls spatiotemporal signaling
- (2016) Michelle L. Halls et al. Science Signaling
- Intracellular mGluR5 plays a critical role in neuropathic pain
- (2016) Kathleen Vincent et al. Nature Communications
- Plasma membrane localization of the μ-opioid receptor controls spatiotemporal signaling
- (2016) Michelle L. Halls et al. Science Signaling
- Inflammation-induced abnormalities in the subcellular localization and trafficking of the neurokinin 1 receptor in the enteric nervous system
- (2015) Daniel P. Poole et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Cell-Penetrating Pepducin Therapy Targeting PAR1 in Subjects With Coronary Artery Disease
- (2015) Paul A. Gurbel et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Neutrophil Elastase Activates Protease-activated Receptor-2 (PAR2) and Transient Receptor Potential Vanilloid 4 (TRPV4) to Cause Inflammation and Pain
- (2015) Peishen Zhao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- G Protein-coupled Receptor (GPCR) Signaling via Heterotrimeric G Proteins from Endosomes
- (2015) Nikoleta G. Tsvetanova et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- G Protein-Coupled Receptors: Dynamic Machines for Signaling Pain and Itch
- (2015) Pierangelo Geppetti et al. NEURON
- Endothelin-converting Enzyme 1 and β-Arrestins Exert Spatiotemporal Control of Substance P-induced Inflammatory Signals
- (2014) Dane D. Jensen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cathepsin S Causes Inflammatory PainviaBiased Agonism of PAR2and TRPV4
- (2014) Peishen Zhao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Calcitonin Gene-Related Peptide Receptor Antagonists: New Therapeutic Agents for Migraine
- (2014) Ian M. Bell JOURNAL OF MEDICINAL CHEMISTRY
- Intracellular mGluR5 Can Mediate Synaptic Plasticity in the Hippocampus
- (2014) C. A. Purgert et al. JOURNAL OF NEUROSCIENCE
- Visualization of arrestin recruitment by a G-protein-coupled receptor
- (2014) Arun K. Shukla et al. NATURE
- Endosomal generation of cAMP in GPCR signaling
- (2014) Jean-Pierre Vilardaga et al. Nature Chemical Biology
- The mGluR5 Antagonist Fenobam Induces Analgesic Conditioned Place Preference in Mice with Spared Nerve Injury
- (2014) Neil C. Lax et al. PLoS One
- Ligand-specific endocytic dwell times control functional selectivity of the cannabinoid receptor 1
- (2014) Jacqueline Flores-Otero et al. Nature Communications
- Protease-activated Receptor 2 (PAR2) Protein and Transient Receptor Potential Vanilloid 4 (TRPV4) Protein Coupling Is Required for Sustained Inflammatory Signaling
- (2013) Daniel P. Poole et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Chemokine Receptor CCR1 Is Constitutively Active, Which Leads to G Protein-independent, β-Arrestin-mediated Internalization
- (2013) C. Taylor Gilliland et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- FRET-based imaging of transbilayer movement of pepducin in living cells by novel intracellular bioreductively activatable fluorescent probes
- (2013) Mieko Tsuji et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
- (2012) Aashish Manglik et al. NATURE
- Current challenges in translational pain research
- (2012) Jianren Mao TRENDS IN PHARMACOLOGICAL SCIENCES
- Characteristics of Opioid Prescriptions in 2009
- (2011) Nora D. Volkow JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Agonist-directed Interactions with Specific β-Arrestins Determine μ-Opioid Receptor Trafficking, Ubiquitination, and Dephosphorylation
- (2011) Chad E. Groer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structure of a nanobody-stabilized active state of the β2 adrenoceptor
- (2011) Søren G. F. Rasmussen et al. NATURE
- Intracellular Metabotropic Glutamate Receptor 5 (mGluR5) Activates Signaling Cascades Distinct from Cell Surface Counterparts
- (2009) Yuh-Jiin I. Jong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phosphorylation of Protease-activated Receptor-2 Differentially Regulates Desensitization and Internalization
- (2009) Tiffany K. Ricks et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Localization of the Endocannabinoid-Degrading Enzyme Fatty Acid Amide Hydrolase in Rat Dorsal Root Ganglion Cells and Its Regulation after Peripheral Nerve Injury
- (2009) I. J. Lever et al. JOURNAL OF NEUROSCIENCE
- In Search of Analgesia: Emerging Poles of GPCRs in Pain
- (2009) L. S. Stone et al. MOLECULAR INTERVENTIONS
- Trends in long-term opioid therapy for chronic non-cancer pain
- (2009) Denise Boudreau et al. PHARMACOEPIDEMIOLOGY AND DRUG SAFETY
- Regulation of CB1 cannabinoid receptor trafficking by the adaptor protein AP-3
- (2008) Raphael Rozenfeld et al. FASEB JOURNAL
- Calmodulin dynamically regulates the trafficking of the metabotropic glutamate receptor mGluR5
- (2008) J. H. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Efficient Inhibition of the Alzheimer's Disease -Secretase by Membrane Targeting
- (2008) L. Rajendran et al. SCIENCE
- 75 years of opioid research: the exciting but vain quest for the Holy Grail
- (2006) Alistair D Corbett et al. BRITISH JOURNAL OF PHARMACOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now