Plasma membrane localization of the μ-opioid receptor controls spatiotemporal signaling

Endothelin-converting Enzyme 1 and β-Arrestins Exert Spatiotemporal Control of Substance P-induced Inflammatory Signals

(2014) Dane D. Jensen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spatial encoding of cyclic AMP signaling specificity by GPCR endocytosis

(2014) Nikoleta G Tsvetanova et al.   Nature Chemical Biology

Heterologous regulation of agonist-independent μ-opioid receptor phosphorylation by protein kinase C

(2013) Susann Illing et al.   BRITISH JOURNAL OF PHARMACOLOGY

G protein-coupled receptor kinase 2 (GRK2) is a Rho-activated scaffold protein for the ERK MAP kinase cascade

(2013) James D. Robinson et al.   CELLULAR SIGNALLING

The Bile Acid Receptor TGR5 Does Not Interact with β-Arrestins or Traffic to Endosomes but Transmits Sustained Signals from Plasma Membrane Rafts

(2013) Dane D. Jensen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Sensitive and High Resolution Localization and Tracking of Membrane Proteins in Live Cells with BRET

(2012) Tien-Hung Lan et al.   TRAFFIC

Molecular Mechanisms of Opioid Receptor-dependent Signaling and Behavior

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Agonist-selective patterns of µ-opioid receptor phosphorylation revealed by phosphosite-specific antibodies

(2011) Christian Doll et al.   BRITISH JOURNAL OF PHARMACOLOGY

Role of the Clathrin Terminal Domain in Regulating Coated Pit Dynamics Revealed by Small Molecule Inhibition

(2011) Lisa von Kleist et al.   CELL

Opioids: a two-faced Janus

(2011) Karsten Ahlbeck   CURRENT MEDICAL RESEARCH AND OPINION

Modulating μ-Opioid Receptor Phosphorylation Switches Agonist-dependent Signaling as Reflected in PKCϵ Activation and Dendritic Spine Stability

(2011) Hui Zheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recovery from  -Opioid Receptor Desensitization after Chronic Treatment with Morphine and Methadone

(2011) N. Quillinan et al.   JOURNAL OF NEUROSCIENCE

Protein Kinase C-Mediated Phosphorylation of the  -Opioid Receptor and Its Effects on Receptor Signaling

(2011) B. Feng et al.   MOLECULAR PHARMACOLOGY

Imaging protein activity in live embryos using fluorescence resonance energy transfer biosensors

(2011) Elena Kardash et al.   Nature Protocols

Agonist-dependent μ-opioid receptor signaling can lead to heterologous desensitization

(2010) Ji Chu et al.   CELLULAR SIGNALLING

Beta-arrestins as regulators of signal termination and transduction: How do they determine what to scaffold?

(2010) Kathryn A. DeFea   CELLULAR SIGNALLING

Involvement of PKCα and G-protein-coupled receptor kinase 2 in agonist-selective desensitization of µ-opioid receptors in mature brain neurons

(2009) CP Bailey et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cellular and Molecular Mechanisms of Pain

(2009) Allan I. Basbaum et al.   CELL

Membrane functional organisation and dynamic of μ-opioid receptors

(2009) André Lopez et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Persistent cAMP-Signals Triggered by Internalized G-Protein–Coupled Receptors

(2009) Davide Calebiro et al.   PLOS BIOLOGY

Neuropeptide FF-sensitive confinement of mu opioid receptor does not involve lipid rafts in SH-SY5Y cells

(2008) Lionel Moulédous et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

G protein-coupled receptor kinase 2 positively regulates epithelial cell migration

(2008) Petronila Penela et al.   EMBO JOURNAL

Cholesterol content drives distinct pharmacological behaviours of µ-opioid receptor in different microdomains of the CHO plasma membrane

(2008) G. Gaibelet et al.   MOLECULAR MEMBRANE BIOLOGY

A genetically encoded fluorescent sensor of ERK activity

(2008) C. D. Harvey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Agonist-selective signaling is determined by the receptor location within the membrane domains

(2008) H. Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA