Advanced Proteomics as a Powerful Tool for Studying Toxins of Human Bacterial Pathogens

Heat-Stable Enterotoxins of Enterotoxigenic Escherichia coli and Their Impact on Host Immunity

(2019) Haixiu Wang et al.   Toxins

LasB and CbpD Virulence Factors of Pseudomonas aeruginosa Carry Multiple Post-Translational Modifications on Their Lysine Residues

(2019) Charlotte Gaviard et al.   JOURNAL OF PROTEOME RESEARCH

Omics of the early molecular dialogue between Frankia alni and Alnus glutinosa and the cellulase synton

(2019) Petar Pujic et al.   ENVIRONMENTAL MICROBIOLOGY

Detection of Endotoxins: From Inferring the Responses of Biological Hosts to the Direct Chemical Analysis of Lipopolysaccharides

(2019) Jackie Jackie et al.   CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY

Mechanisms, Detection, and Relevance of Protein Acetylation in Prokaryotes

(2019) D. G. Christensen et al.   mBio

Binding to The Target Cell Surface Is The Crucial Step in Pore Formation of Hemolysin BL from Bacillus cereus

(2019) Nadja Jessberger et al.   Toxins

Metaproteomics: Much More than Measuring Gene Expression in Microbial Communities

(2019) Manuel Kleiner   mSystems

Membrane Permeabilization by Pore-Forming RTX Toxins: What Kind of Lesions Do These Toxins Form?

(2019) Helena Ostolaza et al.   Toxins

The opportunistic pathogen Stenotrophomonas maltophilia utilizes a type IV secretion system for interbacterial killing

(2019) Ethel Bayer-Santos et al.   PLoS Pathogens

Type VI Secretion System in Pathogenic Escherichia coli: Structure, Role in Virulence, and Acquisition

(2019) Fernando Navarro-Garcia et al.   Frontiers in Microbiology

The Role of Bacillithiol in Gram-Positive Firmicutes

(2018) Pete Chandrangsu et al.   ANTIOXIDANTS & REDOX SIGNALING

Lysine Succinylation and Acetylation in Pseudomonas aeruginosa

(2018) Charlotte Gaviard et al.   JOURNAL OF PROTEOME RESEARCH

Parallel reaction monitoring on a Q Exactive mass spectrometer increases reproducibility of phosphopeptide detection in bacterial phosphoproteomics measurements

(2018) Christoph Taumer et al.   Journal of Proteomics

Proteogenomic insights into uranium tolerance of a Chernobyl's Microbacterium bacterial isolate

(2018) Nicolas Gallois et al.   Journal of Proteomics

Exotoxins and endotoxins: Inducers of inflammatory cytokines

(2018) Jean-Marc Cavaillon   TOXICON

Proteomics of Pseudomonas aeruginosa: the increasing role of post-translational modifications

(2018) Charlotte Gaviard et al.   Expert Review of Proteomics

Data‐independent acquisition‐based SWATH‐MS for quantitative proteomics: a tutorial

(2018) Christina Ludwig et al.   Molecular Systems Biology

Structural and Mechanistic Features of ClyA-Like α-Pore-Forming Toxins

(2018) Bastian Bräuning et al.   Toxins

Redox regulation by reversible protein S-thiolation in Gram-positive bacteria

(2018) Marcel Imber et al.   Redox Biology

Pharmacological Targeting of Pore-Forming Toxins as Adjunctive Therapy for Invasive Bacterial Infection

(2018) Tamara Escajadillo et al.   Toxins

Type VI secretion system baseplate

(2018) Alan R. Davidson et al.   Nature Microbiology

Regulation, Function, and Detection of Protein Acetylation in Bacteria

(2017) Valerie J. Carabetta et al.   JOURNAL OF BACTERIOLOGY

Comparative Proteomics of Enterotoxigenic Escherichia coli Reveals Differences in Surface Protein Production and Similarities in Metabolism

(2017) Veronika Kuchařová Pettersen et al.   JOURNAL OF PROTEOME RESEARCH

Methods, Tools and Current Perspectives in Proteogenomics

(2017) Kelly V. Ruggles et al.   MOLECULAR & CELLULAR PROTEOMICS

Assembly mechanism of the α-pore–forming toxin cytolysin A from Escherichia coli

(2017) Daniel Roderer et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Phospholipase A activity of adenylate cyclase toxin mediates translocation of its adenylate cyclase domain

(2017) David González-Bullón et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein Acetylation and Its Role in Bacterial Virulence

(2017) Jie Ren et al.   TRENDS IN MICROBIOLOGY

Bacterial toxins: Offensive, defensive, or something else altogether?

(2017) Justine K. Rudkin et al.   PLoS Pathogens

Distinct Neurotoxicity Profile of Listeriolysin O from Listeria monocytogenes

(2017) Jana Maurer et al.   Toxins

NMR structure of the Bacillus cereus hemolysin II C-terminal domain reveals a novel fold

(2017) Anne R. Kaplan et al.   Scientific Reports

Structural, physicochemical and dynamic features conserved within the aerolysin pore-forming toxin family

(2017) Nuria Cirauqui et al.   Scientific Reports

Formation of small transmembrane pores: An intermediate stage on the way to Bacillus cereus non-hemolytic enterotoxin (Nhe) full pores in the absence of NheA

(2016) Kui Zhu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Next-generation proteomics faces new challenges in environmental biotechnology

(2016) Jean Armengaud   CURRENT OPINION IN BIOTECHNOLOGY

Type VI secretion and anti-host effectors

(2016) Abderrahman Hachani et al.   CURRENT OPINION IN MICROBIOLOGY

Shotgun proteomics of bacterial pathogens: advances, challenges and clinical implications

(2016) Maja Semanjski et al.   Expert Review of Proteomics

Proteomic characterization of Nα- and Nε-acetylation in Acinetobacter baumannii

(2016) Takfarinas Kentache et al.   Journal of Proteomics

Deciphering the interactions between the Bacillus cereus linear plasmid, pBClin15, and its host by high-throughput comparative proteomics

(2016) Jean-Paul Madeira et al.   Journal of Proteomics

Foodborne pathogens and their toxins

(2016) Tamara Martinović et al.   Journal of Proteomics

Antibody Binding Studies Reveal Conformational Flexibility of the Bacillus cereus Non-Hemolytic Enterotoxin (Nhe) A-Component

(2016) A. Didier et al.   PLoS One

The Ins and Outs of Anthrax Toxin

(2016) Sarah Friebe et al.   Toxins

Type Three Secretion System in Attaching and Effacing Pathogens

(2016) Meztlli O. Gaytán et al.   Frontiers in Cellular and Infection Microbiology

Mass Spectrometry Targeted Assays as a Tool to Improve Our Understanding of Post-translational Modifications in Pathogenic Bacteria

(2016) Nelson C. Soares et al.   Frontiers in Microbiology

Cytotoxic Potential of Bacillus cereus Strains ATCC 11778 and 14579 Against Human Lung Epithelial Cells Under Microaerobic Growth Conditions

(2016) Kathleen Kilcullen et al.   Frontiers in Microbiology

Excretion of cytoplasmic proteins in Staphylococcus is most likely not due to cell lysis

(2015) Patrick Ebner et al.   CURRENT GENETICS

Excretion of cytosolic proteins (ECP) in bacteria

(2015) Friedrich Götz et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Disulfide-Bond-Forming Pathways in Gram-Positive Bacteria

(2015) Melissa E. Reardon-Robinson et al.   JOURNAL OF BACTERIOLOGY

Novel Host Proteins and Signaling Pathways in EnteropathogenicE. coliPathogenesis Identified by Global Phosphoproteome Analysis

(2015) Roland Scholz et al.   MOLECULAR & CELLULAR PROTEOMICS

One-hour proteome analysis in yeast

(2015) Alicia L Richards et al.   Nature Protocols

Pore-forming toxins: ancient, but never really out of fashion

(2015) Matteo Dal Peraro et al.   NATURE REVIEWS MICROBIOLOGY

In vivo EPR on spin labeled colicin A reveals an oligomeric assembly of the pore-forming domain in E. coli membranes

(2015) S. Dunkel et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

A decade of metaproteomics: Where we stand and what the future holds

(2015) Paul Wilmes et al.   PROTEOMICS

Protein lysine acetylation in bacteria: Current state of the art

(2015) Tassadit Ouidir et al.   PROTEOMICS

Proteomic profiling of lysine acetylation inPseudomonas aeruginosareveals the diversity of acetylated proteins

(2015) Tassadit Ouidir et al.   PROTEOMICS

Proteogenomics of rare taxonomic phyla: A prospective treasure trove of protein coding genes

(2015) Dhirendra Kumar et al.   PROTEOMICS

Structural basis for pore-forming mechanism of staphylococcal α-hemolysin

(2015) Takaki Sugawara et al.   TOXICON

Autophagy and endosomal trafficking inhibition by Vibrio cholerae MARTX toxin phosphatidylinositol-3-phosphate-specific phospholipase A1 activity

(2015) Shivani Agarwal et al.   Nature Communications

Membrane-Binding Mechanism of Clostridium perfringens Alpha-Toxin

(2015) Masataka Oda et al.   Toxins

Proteomics identifies Bacillus cereus EntD as a pivotal protein for the production of numerous virulence factors

(2015) Hélène Omer et al.   Frontiers in Microbiology

Time dynamics of the Bacillus cereus exoproteome are shaped by cellular oxidation

(2015) Jean-Paul Madeira et al.   Frontiers in Microbiology

Quantitative Proteome Analyses Identify PrfA-Responsive Proteins and Phosphoproteins in Listeria monocytogenes

(2014) Sandeep Kumar Misra et al.   JOURNAL OF PROTEOME RESEARCH

Proteogenomics: concepts, applications and computational strategies

(2014) Alexey I Nesvizhskii   NATURE METHODS

Novel bacterial ADP-ribosylating toxins: structure and function

(2014) Nathan C. Simon et al.   NATURE REVIEWS MICROBIOLOGY

Precision Measurement of the Mass and Lifetime of theΞb0Baryon

(2014) R. Aaij et al.   PHYSICAL REVIEW LETTERS

Proteomic Evidences for Rex Regulation of Metabolism in Toxin-Producing Bacillus cereus ATCC 14579

(2014) Sabrina Laouami et al.   PLoS One

N-terminomics and proteogenomics, getting off to a good start

(2014) Erica M. Hartmann et al.   PROTEOMICS

Extracellular Ser/Thr/Tyr phosphorylated proteins ofPseudomonas aeruginosaPA14 strain

(2014) Tassadit Ouidir et al.   PROTEOMICS

Molecular basis of transmembrane beta-barrel formation of staphylococcal pore-forming toxins

(2014) Daichi Yamashita et al.   Nature Communications

Molecular basis of host specificity in human pathogenic bacteria

(2014) Xiaolei Pan et al.   Emerging Microbes & Infections

Methionine oxidation and reduction in proteins

(2013) Geumsoo Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

YaxAB, a Yersinia enterocolitica Pore-Forming Toxin Regulated by RovA

(2013) Nikki J. Wagner et al.   INFECTION AND IMMUNITY

The phosphoproteome and its physiological dynamics in Staphylococcus aureus

(2013) Katrin Bäsell et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

OhrRA functions as a redox-responsive system controlling toxinogenesis in Bacillus cereus

(2013) Gérémy Clair et al.   Journal of Proteomics

Beyond gene expression: The impact of protein post-translational modifications in bacteria

(2013) Joel A. Cain et al.   Journal of Proteomics

Multiplexed and data-independent tandem mass spectrometry for global proteome profiling

(2013) John D. Chapman et al.   MASS SPECTROMETRY REVIEWS

Structure of the NheA Component of the Nhe Toxin from Bacillus cereus: Implications for Function

(2013) Magdah Ganash et al.   PLoS One

The Bacillus cereus Hbl and Nhe Tripartite Enterotoxin Components Assemble Sequentially on the Surface of Target Cells and Are Not Interchangeable

(2013) Inka Sastalla et al.   PLoS One

General Aspects and Recent Advances on Bacterial Protein Toxins

(2013) E. Lemichez et al.   Cold Spring Harbor Perspectives in Medicine

The Pore-Forming Haemolysins of Bacillus Cereus: A Review

(2013) Nalini Ramarao et al.   Toxins

Proteomics reveals evidence of cross-talk between protein modifications in bacteria: focus on acetylation and phosphorylation

(2012) Boumediene Soufi et al.   CURRENT OPINION IN MICROBIOLOGY

Shotgun nanoLC-MS/MS proteogenomics to document MALDI-TOF biomarkers for screening new members of theRuegeriagenus

(2012) Joseph Alexander Christie-Oleza et al.   ENVIRONMENTAL MICROBIOLOGY

Exoproteomics: exploring the world around biological systems

(2012) Jean Armengaud et al.   Expert Review of Proteomics

The RTX pore-forming toxin α-hemolysin of uropathogenicEscherichia coli: progress and perspectives

(2012) Travis J Wiles et al.   Future Microbiology

Restricting Fermentative Potential by Proteome Remodeling

(2012) Gérémy Clair et al.   MOLECULAR & CELLULAR PROTEOMICS

The Non-Flagellar Type III Secretion System Evolved from the Bacterial Flagellum and Diversified into Host-Cell Adapted Systems

(2012) Sophie S. Abby et al.   PLoS Genetics

S-Glutathionylation: From Molecular Mechanisms to Health Outcomes

(2011) Ying Xiong et al.   ANTIOXIDANTS & REDOX SIGNALING

Membrane assembly of the cholesterol-dependent cytolysin pore complex

(2011) Eileen M. Hotze et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Prevalence and Significance of Plasmid Maintenance Functions in the Virulence Plasmids of Pathogenic Bacteria

(2011) Manjistha Sengupta et al.   INFECTION AND IMMUNITY

DBETH: A Database of Bacterial Exotoxins for Human

(2011) Abhijit Chakraborty et al.   NUCLEIC ACIDS RESEARCH

Phosphoproteome analysis of the pathogenic bacterium Helicobacter pylori reveals over-representation of tyrosine phosphorylation and multiply phosphorylated proteins

(2011) Ruiguang Ge et al.   PROTEOMICS

Pathogen-Mediated Posttranslational Modifications: A Re-emerging Field

(2010) David Ribet et al.   CELL

Chemical ‘omics’ approaches for understanding protein cysteine oxidation in biology

(2010) Stephen E Leonard et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Post-translational modifications in host cells during bacterial infection

(2010) David Ribet et al.   FEBS LETTERS

Cytotoxicity of the Bacillus cereus Nhe Enterotoxin Requires Specific Binding Order of Its Three Exoprotein Components

(2010) T. Lindback et al.   INFECTION AND IMMUNITY

Expanding the Known Repertoire of Virulence Factors Produced byBacillus cereusthrough Early Secretome Profiling in Three Redox Conditions

(2010) Gérémy Clair et al.   MOLECULAR & CELLULAR PROTEOMICS

AB Toxins: A Paradigm Switch from Deadly to Desirable

(2010) Oludare Odumosu et al.   Toxins

Inactivation of Escherichia coli Endotoxin by Soft Hydrothermal Processing

(2009) T. Miyamoto et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

A perfect genome annotation is within reach with the proteomics and genomics alliance

(2009) Jean Armengaud   CURRENT OPINION IN MICROBIOLOGY

Passive administration of monoclonal antibodies to Anthrolysin O prolong survival in mice lethally infected with Bacillus anthracis

(2008) Antonio Nakouzi et al.   BMC MICROBIOLOGY

X-ray crystal structure of the B component of Hemolysin BL fromBacillus cereus

(2008) Mahendra Madegowda et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS