Combinations of Antimicrobial Polymers with Nanomaterials and Bioactives to Improve Biocidal Therapies
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Combinations of Antimicrobial Polymers with Nanomaterials and Bioactives to Improve Biocidal Therapies
Authors
Keywords
-
Journal
Polymers
Volume 11, Issue 11, Pages 1789
Publisher
MDPI AG
Online
2019-11-02
DOI
10.3390/polym11111789
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Drug combinations: a strategy to extend the life of antibiotics in the 21st century
- (2019) Mike Tyers et al. NATURE REVIEWS MICROBIOLOGY
- Modification of chitosan and chitosan nanoparticle by long chain pyridinium compounds: Synthesis, characterization, antibacterial, and antioxidant activities
- (2019) Sakineh Omidi et al. CARBOHYDRATE POLYMERS
- Preparation and characteristics of antibacterial chitosan films modified with N-halamine for biomedical application
- (2019) Marta Chylińska et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Synergism in the Antibacterial Action of Ternary Mixtures Involving Silver Nanoparticles, Chitosan and Antibiotics
- (2018) Marcelo Brasil et al. JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
- Nitric Oxide-Loaded Antimicrobial Polymer for the Synergistic Eradication of Bacterial Biofilm
- (2018) Rashin Namivandi-Zangeneh et al. ACS Macro Letters
- Tailored synthesis of polymer-brush-grafted mesoporous silicas with N-halamine and quaternary ammonium groups for antimicrobial applications
- (2018) Yingfeng Wang et al. JOURNAL OF COLLOID AND INTERFACE SCIENCE
- Sol–gel synthesis of Mg(OH)2 and Ca(OH)2 nanoparticles: a comparative study of their antifungal activity in partially quaternized p(DMAEMA) nanocomposite films
- (2018) A. Sierra-Fernandez et al. JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
- Antibacterial and antifungal properties of dendronized silver and gold nanoparticles with cationic carbosilane dendrons
- (2017) Cornelia E. Peña-González et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Synergistic Antibacterial Effects of Chitosan-Caffeic Acid Conjugate against Antibiotic-Resistant Acne-Related Bacteria
- (2017) Ji-Hoon Kim et al. Marine Drugs
- Cationic peptidopolysaccharides synthesized by ‘click’ chemistry with enhanced broad-spectrum antimicrobial activities
- (2017) Yajuan Su et al. Polymer Chemistry
- Antibacterial membranes based on chitosan and quaternary ammonium salts modified nanocrystalline cellulose
- (2017) Ying Liu et al. POLYMERS FOR ADVANCED TECHNOLOGIES
- Antimicrobial Polymers in the Nano-World
- (2017) Marta Álvarez-Paino et al. Nanomaterials
- Trio Act of Boronolectin with Antibiotic-Metal Complexed Macromolecules toward Broad-Spectrum Antimicrobial Efficacy
- (2017) Peng Yang et al. ACS Infectious Diseases
- Anti-biofilm action of nitric oxide-releasing alkyl-modified poly(amidoamine) dendrimers against Streptococcus mutans
- (2016) Christopher J. Backlund et al. Acta Biomaterialia
- Killing of Staphylococcus aureus via Magnetic Hyperthermia Mediated by Magnetotactic Bacteria
- (2016) Changyou Chen et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Green antimicrobial coating based on quaternised chitosan/organic montmorillonite/Ag NPs nanocomposites
- (2016) Kaihang Chen et al. Journal of Experimental Nanoscience
- Size-dependent antimicrobial properties of the cobalt ferrite nanoparticles
- (2016) Rokas Žalnėravičius et al. JOURNAL OF NANOPARTICLE RESEARCH
- Mechanisms of the Antimicrobial Activities of Graphene Materials
- (2016) Xuefeng Zou et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Amphiphilic cationic copolymers with ciprofloxacin: preparation and antimicrobial activities
- (2016) Man He et al. NEW JOURNAL OF CHEMISTRY
- Co-delivery of nitric oxide and antibiotic using polymeric nanoparticles
- (2016) Thuy-Khanh Nguyen et al. Chemical Science
- Cationic polycarbonate-grafted superparamagnetic nanoparticles with synergistic dual-modality antimicrobial activity
- (2016) Lu Pu et al. Biomaterials Science
- Recent advances in thromboresistant and antimicrobial polymers for biomedical applications: just say yes to nitric oxide (NO)
- (2016) Yaqi Wo et al. Biomaterials Science
- Efficient Eradication of Mature Pseudomonas aeruginosa Biofilm via Controlled Delivery of Nitric Oxide Combined with Antimicrobial Peptide and Antibiotics
- (2016) Hang Ren et al. Frontiers in Microbiology
- Synergistic activity between an antimicrobial polyacrylamide and daptomycin versusStaphylococcus aureusbiofilm
- (2016) Wafi Siala et al. Pathogens and Disease
- Active Release of Nitric Oxide-Releasing Dendrimers from Electrospun Polyurethane Fibers
- (2016) Brittany V. Worley et al. ACS Biomaterials-Science & Engineering
- Active Release of Nitric Oxide-Releasing Dendrimers from Electrospun Polyurethane Fibers
- (2016) Brittany V. Worley et al. ACS Biomaterials Science & Engineering
- Development of Noncytotoxic Chitosan–Gold Nanocomposites as Efficient Antibacterial Materials
- (2015) Anna Regiel-Futyra et al. ACS Applied Materials & Interfaces
- CO-Releasing Polymers Exert Antimicrobial Activity
- (2015) Diep Nguyen et al. BIOMACROMOLECULES
- Grafting of ionic liquids on stainless steel surface for antibacterial application
- (2015) Li Qing Pang et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- New antibiotics and antimicrobial combination therapy for the treatment of gram-negative bacterial infections
- (2015) Matteo Bassetti et al. Current Opinion in Critical Care
- Antimicrobial interactions: mechanisms and implications for drug discovery and resistance evolution
- (2015) Tobias Bollenbach CURRENT OPINION IN MICROBIOLOGY
- Antimicrobial Coatings with Dual Cationic and N-Halamine Character: Characterization and Biocidal Efficacy
- (2015) Luis J. Bastarrachea et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Antimicrobial Activity of Gallic Acid-Grafted-Chitosan Against Fish Pathogens
- (2015) Do-Hyung Kim et al. JOURNAL OF CARBOHYDRATE CHEMISTRY
- Anti-Biofilm Efficacy of Dual-Action Nitric Oxide-Releasing Alkyl Chain Modified Poly(amidoamine) Dendrimers
- (2015) Brittany V. Worley et al. MOLECULAR PHARMACEUTICS
- Poly(Propylene Imine) Dendrimers and Amoxicillin as Dual-Action Antibacterial Agents
- (2015) Natalia Wrońska et al. MOLECULES
- The key role of the scaffold on the efficiency of dendrimer nanodrugs
- (2015) Anne-Marie Caminade et al. Nature Communications
- Silver salts of carboxylic acid terminated generation 1 poly (propyl ether imine) (PETIM) dendron and dendrimers as antimicrobial agents against S. aureus and MRSA
- (2015) Nadia Suleman et al. RSC Advances
- Antimicrobial peptide-conjugated graphene oxide membrane for efficient removal and effective killing of multiple drug resistant bacteria
- (2015) Rajashekhar Kanchanapally et al. RSC Advances
- Review on Zinc Oxide Nanoparticles: Antibacterial Activity and Toxicity Mechanism
- (2015) Amna Sirelkhatim et al. Nano-Micro Letters
- Antimicrobial and cell-compatible surface-attached polymer networks – how the correlation of chemical structure to physical and biological data leads to a modified mechanism of action
- (2015) Peng Zou et al. Journal of Materials Chemistry B
- Synthesis, characterization and antimicrobial activities of water-soluble amphiphilic copolymers containing ciprofloxacin and quaternary ammonium salts
- (2015) Man He et al. Journal of Materials Chemistry B
- Review on Zinc Oxide Nanoparticles: Antibacterial Activity and Toxicity Mechanism
- (2015) Amna Sirelkhatim et al. Nano-Micro Letters
- Polymer-Ag Nanocomposites with Enhanced Antimicrobial Activity against Bacterial Infection
- (2014) Lin Mei et al. ACS Applied Materials & Interfaces
- Functional Gold Nanoparticles as Potent Antimicrobial Agents against Multi-Drug-Resistant Bacteria
- (2014) Xiaoning Li et al. ACS Nano
- Optimized polymeric film-based nitric oxide delivery inhibits bacterial growth in a mouse burn wound model
- (2014) Elizabeth J. Brisbois et al. Acta Biomaterialia
- A Novel Wound Dressing Based on Ag/Graphene Polymer Hydrogel: Effectively Kill Bacteria and Accelerate Wound Healing
- (2014) Zengjie Fan et al. ADVANCED FUNCTIONAL MATERIALS
- Antimicrobial cotton containing N-halamine and quaternary ammonium groups by grafting copolymerization
- (2014) Ying Liu et al. APPLIED SURFACE SCIENCE
- Antibacterial and synergic effects of gallic acid-grafted-chitosan with β-lactams against methicillin-resistant Staphylococcus aureus (MRSA)
- (2014) Dae-Sung Lee et al. CANADIAN JOURNAL OF MICROBIOLOGY
- Antimicrobial Activity of Chitosan Derivatives Containing N-Quaternized Moieties in Its Backbone: A Review
- (2014) Alessandro Martins et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Dual action antimicrobial surfaces via combined nitric oxide and silver release
- (2014) Wesley L. Storm et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- Antimicrobial Metallopolymers and Their Bioconjugates with Conventional Antibiotics against Multidrug-Resistant Bacteria
- (2014) Jiuyang Zhang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Antimicrobial Polycarbonates: Investigating the Impact of Nitrogen-Containing Heterocycles as Quaternizing Agents
- (2014) Victor Wee Lin Ng et al. MACROMOLECULES
- Multivalent polymer–Au nanocomposites with cationic surfaces displaying enhanced antimicrobial activity
- (2014) Lin Mei et al. Polymer Chemistry
- Combination antibiotic therapy for multidrug-resistant Gram-negative bacteria
- (2014) Thomas Tängdén UPSALA JOURNAL OF MEDICAL SCIENCES
- Novel quaternary phosphonium-type cationic polyacrylamide and elucidation of dual-functional antibacterial/antiviral activity
- (2014) Yan Xue et al. RSC Advances
- Antimicrobial Polymers
- (2014) Anjali Jain et al. Advanced Healthcare Materials
- Carbon-Based Nanomaterials: Multifunctional Materials for Biomedical Engineering
- (2013) Chaenyung Cha et al. ACS Nano
- Synergistic Co-Delivery of Membrane-Disrupting Polymers with Commercial Antibiotics against Highly Opportunistic Bacteria
- (2013) Victor Wee Lin Ng et al. ADVANCED MATERIALS
- Antimicrobial N-Halamine Polymers and Coatings: A Review of Their Synthesis, Characterization, and Applications
- (2013) Franck Hui et al. BIOMACROMOLECULES
- Nitric oxide-releasing chitosan oligosaccharides as antibacterial agents
- (2013) Yuan Lu et al. BIOMATERIALS
- Antibacterial cotton treated with N-halamine and quaternary ammonium salt
- (2013) Ying Liu et al. CELLULOSE
- Dual action bactericides: Quaternary ammonium/N-halamine-functionalized cellulose fiber
- (2013) Bojian Hu et al. JOURNAL OF APPLIED POLYMER SCIENCE
- Graphene oxide exhibits broad-spectrum antimicrobial activity against bacterial phytopathogens and fungal conidia by intertwining and membrane perturbation
- (2013) Juanni Chen et al. Nanoscale
- Enhancement of antimicrobial activity by co-administration of poly(propylene imine) dendrimers and nadifloxacin
- (2013) Aleksandra Felczak et al. NEW JOURNAL OF CHEMISTRY
- Mechanisms of Silver Nanoparticle Release, Transformation and Toxicity: A Critical Review of Current Knowledge and Recommendations for Future Studies and Applications
- (2013) Bogumiła Reidy et al. Materials
- One-pot green synthesis and antimicrobial activity of exfoliated Ag NP-loaded quaternized chitosan/clay nanocomposites
- (2013) Bo Liu et al. RSC Advances
- Eco-friendly synthesis of regenerable antimicrobial polymeric resin with N-halamine and quaternary ammonium salt groups
- (2013) Zhiqiang Jie et al. RSC Advances
- Iodine-Stabilized Cu Nanoparticle Chitosan Composite for Antibacterial Applications
- (2012) Sadhucharan Mallick et al. ACS Applied Materials & Interfaces
- Magnetic Nanoparticle Targeted Hyperthermia of Cutaneous Staphylococcus aureus Infection
- (2012) Min-Ho Kim et al. ANNALS OF BIOMEDICAL ENGINEERING
- Dual Action Antimicrobials: Nitric Oxide Release from Quaternary Ammonium-Functionalized Silica Nanoparticles
- (2012) Alexis W. Carpenter et al. BIOMACROMOLECULES
- Nitric Oxide-Releasing Dendrimers as Antibacterial Agents
- (2012) Bin Sun et al. BIOMACROMOLECULES
- Characterization and antibacterial properties of genipin-crosslinked chitosan/poly(ethylene glycol)/ZnO/Ag nanocomposites
- (2012) Yangshuo Liu et al. CARBOHYDRATE POLYMERS
- Antimicrobial activity of carboxymethyl chitosan/polyethylene oxide nanofibers embedded silver nanoparticles
- (2012) Moustafa M.G. Fouda et al. CARBOHYDRATE POLYMERS
- Nitric oxide release: Part II. Therapeutic applications
- (2012) Alexis W. Carpenter et al. CHEMICAL SOCIETY REVIEWS
- Activity of Chitosans in combination with antibiotics in Pseudomonas aeruginosa
- (2012) San Tin et al. International Journal of Biological Sciences
- Silver Ions Release from Antibacterial Chitosan Films Containing in Situ Generated Silver Nanoparticles
- (2012) Gracia López-Carballo et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Preparation of antibacterial PDMAEMA-functionalized multiwalled carbon nanotube via atom transfer radical polymerization
- (2012) Young Tae Joo et al. JOURNAL OF APPLIED POLYMER SCIENCE
- The effect of a branched architecture on the antimicrobial activity of poly(sulfone amines) and poly(sulfone amine)/silver nanocomposites
- (2012) Ruibin Wang et al. JOURNAL OF MATERIALS CHEMISTRY
- Facile preparation and synergistic antibacterial effect of three-component Cu/TiO2/CS nanoparticles
- (2012) Shiguo Chen et al. JOURNAL OF MATERIALS CHEMISTRY
- Antibacterial Efficiency of Graphene Nanosheets against Pathogenic Bacteria via Lipid Peroxidation
- (2012) Karthikeyan Krishnamoorthy et al. Journal of Physical Chemistry C
- N-halamine copolymers for biocidal coatings
- (2012) Idris Cerkez et al. REACTIVE & FUNCTIONAL POLYMERS
- Antibacterial properties of nanoparticles
- (2012) Mohammad J. Hajipour et al. TRENDS IN BIOTECHNOLOGY
- Antimicrobial macromolecules: synthesis methods and future applications
- (2012) Peng Li et al. RSC Advances
- New Biocide with BothN-Chloramine and Quaternary Ammonium Moieties Exerts Enhanced Bactericidal Activity
- (2012) Lingdong Li et al. Advanced Healthcare Materials
- Antimicrobial Polymers in Solution and on Surfaces: Overview and Functional Principles
- (2012) Felix Siedenbiedel et al. Polymers
- N-Halamine Copolymers for Use in Antimicrobial Paints
- (2011) Hasan B. Kocer et al. ACS Applied Materials & Interfaces
- Polymeric Antimicrobial N-Halamine Epoxides
- (2011) Hasan B. Kocer et al. ACS Applied Materials & Interfaces
- Aqueous Synthesis of Silver Nanoparticle Embedded Cationic Polymer Nanofibers and Their Antibacterial Activity
- (2011) Jooyoung Song et al. ACS Applied Materials & Interfaces
- Antibacterial Activity of Graphite, Graphite Oxide, Graphene Oxide, and Reduced Graphene Oxide: Membrane and Oxidative Stress
- (2011) Shaobin Liu et al. ACS Nano
- Silver polymeric nanocomposites as advanced antimicrobial agents: Classification, synthetic paths, applications, and perspectives
- (2011) Panagiotis Dallas et al. ADVANCES IN COLLOID AND INTERFACE SCIENCE
- Synthesis and characterization of chitosan–PEG–Ag nanocomposites for antimicrobial application
- (2011) K.S.V. Krishna Rao et al. CARBOHYDRATE POLYMERS
- Combination therapies for combating antimicrobial resistance
- (2011) Michael A Fischbach CURRENT OPINION IN MICROBIOLOGY
- Coping with antibiotic resistance: combining nanoparticles with antibiotics and other antimicrobial agents
- (2011) Adil M Allahverdiyev et al. Expert Review of Anti-Infective Therapy
- Effective functionalization of multiwalled carbon nanotube with amphiphilic poly(propyleneimine) dendrimer carrying silver nanoparticles for better dispersability and antimicrobial activity
- (2011) E. Murugan et al. JOURNAL OF COLLOID AND INTERFACE SCIENCE
- The crisis of no new antibiotics—what is the way forward?
- (2011) Laura JV Piddock LANCET INFECTIOUS DISEASES
- N-Halamine Biocidal Coatings via a Layer-by-Layer Assembly Technique
- (2011) Idris Cerkez et al. LANGMUIR
- Synergistic Antibacterial Brilliant Blue/Reduced Graphene Oxide/Quaternary Phosphonium Salt Composite with Excellent Water Solubility and Specific Targeting Capability
- (2011) Xiang Cai et al. LANGMUIR
- PAMAM dendrimer-azithromycin conjugate nanodevices for the treatment of Chlamydia trachomatis infections
- (2011) Manoj K. Mishra et al. Nanomedicine-Nanotechnology Biology and Medicine
- Polymeric materials with antimicrobial activity
- (2011) Alexandra Muñoz-Bonilla et al. PROGRESS IN POLYMER SCIENCE
- Silver nanoparticles are broad-spectrum bactericidal and virucidal compounds
- (2011) Humberto H Lara et al. JOURNAL OF NANOBIOTECHNOLOGY
- Antistaphylococcal Nanocomposite Films Based on Enzyme−Nanotube Conjugates
- (2010) Ravindra C. Pangule et al. ACS Nano
- Toxicity of Graphene and Graphene Oxide Nanowalls Against Bacteria
- (2010) Omid Akhavan et al. ACS Nano
- Graphene and Graphene Oxide: Synthesis, Properties, and Applications
- (2010) Yanwu Zhu et al. ADVANCED MATERIALS
- Synergistic effects of chitosan–guanidine complexes on enhancing antimicrobial activity and wet-strength of paper
- (2010) Shengling Sun et al. BIORESOURCE TECHNOLOGY
- Potential of chitin/chitosan-bearing materials for uranium recovery: An interdisciplinary review
- (2010) Riccardo A.A. Muzzarelli CARBOHYDRATE POLYMERS
- Synthesis and characterization of chitosan/ZnO nanoparticle composite membranes
- (2010) Li-Hua Li et al. CARBOHYDRATE RESEARCH
- Preparation, characterization and antimicrobial activities of chitosan/Ag/ZnO blend films
- (2010) Li-Hua Li et al. CHEMICAL ENGINEERING JOURNAL
- P(4-VP) based nanoparticles and composites with dual action as antimicrobial materials
- (2010) Ozgur Ozay et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- The continuing crisis in antibiotic resistance
- (2010) G.L. French INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Antimicrobial properties of chitosan and mode of action: A state of the art review
- (2010) Ming Kong et al. INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
- Preparation of silver nanoparticles with antimicrobial activities and the researches of their biocompatibilities
- (2010) X. L. Cao et al. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
- A review of the antibacterial effects of silver nanomaterials and potential implications for human health and the environment
- (2010) Catalina Marambio-Jones et al. JOURNAL OF NANOPARTICLE RESEARCH
- Heightened Reactive Oxygen Species Generation in the Antimicrobial Activity of a Three Component Iodinated Chitosan−Silver Nanoparticle Composite
- (2010) Madhuchanda Banerjee et al. LANGMUIR
- Synergy of Nitric Oxide and Silver Sulfadiazine against Gram-Negative, Gram-Positive, and Antibiotic-Resistant Pathogens
- (2010) Benjamin J. Privett et al. MOLECULAR PHARMACEUTICS
- Synthesis, characterization, and evaluation of antimicrobial and cytotoxic effect of silver and titanium nanoparticles
- (2010) Fidel Martinez-Gutierrez et al. Nanomedicine-Nanotechnology Biology and Medicine
- Disruption and Activation of Blood Platelets in Contact with an Antimicrobial Composite Coating Consisting of a Pyridinium Polymer and AgBr Nanoparticles
- (2009) Kris N. Stevens et al. ACS Applied Materials & Interfaces
- Sharper and Faster “Nano Darts” Kill More Bacteria: A Study of Antibacterial Activity of Individually Dispersed Pristine Single-Walled Carbon Nanotube
- (2009) Shaobin Liu et al. ACS Nano
- Influences of protein films on antibacterial or bacteria-repellent surface coatings in a model system using silicon wafers
- (2009) Rainer Müller et al. BIOMATERIALS
- Cationic surfactant mediated exfoliation of graphite into graphene flakes
- (2009) Sajini Vadukumpully et al. CARBON
- Fabrication of porous chitosan films impregnated with silver nanoparticles: A facile approach for superior antibacterial application
- (2009) K. Vimala et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Synthesis of a Water-Soluble Siloxane Copolymer and Its Application for Antimicrobial Coatings
- (2009) L. Kou et al. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
- Gold Nanoparticles in Biology: Beyond Toxicity to Cellular Imaging
- (2008) Catherine J. Murphy et al. ACCOUNTS OF CHEMICAL RESEARCH
- Synergy between Polyethylenimine and Different Families of Antibiotics against a Resistant Clinical Isolate of Pseudomonas aeruginosa
- (2008) H. Khalil et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Silver nanoparticles as a new generation of antimicrobials
- (2008) Mahendra Rai et al. BIOTECHNOLOGY ADVANCES
- Physicochemical Determinants of Multiwalled Carbon Nanotube Bacterial Cytotoxicity
- (2008) Seoktae Kang et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- In vitro activity of antibiotic combinations against Pseudomonas aeruginosa biofilm and planktonic cultures
- (2008) Marie Tré-Hardy et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Antibacterial Effects of Carbon Nanotubes: Size Does Matter!
- (2008) Seoktae Kang et al. LANGMUIR
- The inhibitory effects of silver nanoparticles, silver ions, and silver chloride colloids on microbial growth
- (2008) Okkyoung Choi et al. WATER RESEARCH
- Antimicrobial nanomaterials for water disinfection and microbial control: Potential applications and implications
- (2008) Qilin Li et al. WATER RESEARCH
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started