C9orf72-generated poly-GR and poly-PR do not directly interfere with nucleocytoplasmic transport
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
C9orf72-generated poly-GR and poly-PR do not directly interfere with nucleocytoplasmic transport
Authors
Keywords
-
Journal
Scientific Reports
Volume 9, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-10-31
DOI
10.1038/s41598-019-52035-6
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Therapeutic Dissolution of Aberrant Phases by Nuclear-Import Receptors
- (2019) Lin Guo et al. TRENDS IN CELL BIOLOGY
- Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death
- (2019) Fatima Gasset-Rosa et al. NEURON
- Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy
- (2019) Jeannie Chew et al. Molecular Neurodegeneration
- Widespread FUS mislocalization is a molecular hallmark of amyotrophic lateral sclerosis
- (2019) Giulia E Tyzack et al. BRAIN
- Modulation of actin polymerization affects nucleocytoplasmic transport in multiple forms of amyotrophic lateral sclerosis
- (2019) Anthony Giampetruzzi et al. Nature Communications
- Stress Granule Assembly Disrupts Nucleocytoplasmic Transport
- (2018) Ke Zhang et al. CELL
- Poly(GR) impairs protein translation and stress granule dynamics in C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis
- (2018) Yong-Jie Zhang et al. NATURE MEDICINE
- TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD
- (2018) Ching-Chieh Chou et al. NATURE NEUROSCIENCE
- Insights into C9ORF72 -Related ALS/FTD from Drosophila and iPSC Models
- (2018) Yeliz Yuva-Aydemir et al. TRENDS IN NEUROSCIENCES
- A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration
- (2018) Daniel A Solomon et al. BRAIN
- C9orf72-mediated ALS and FTD: multiple pathways to disease
- (2018) Rubika Balendra et al. Nature Reviews Neurology
- Moonlighting nuclear pore proteins: tissue-specific nucleoporin function in health and disease
- (2018) Ramona Jühlen et al. HISTOCHEMISTRY AND CELL BIOLOGY
- Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics
- (2017) Steven Boeynaems et al. MOLECULAR CELL
- Toxic PRnpoly-dipeptides encoded by theC9orf72repeat expansion block nuclear import and export
- (2017) Kevin Y. Shi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients
- (2017) Wenting Guo et al. Nature Communications
- Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens
- (2017) Traver Hart et al. G3-Genes Genomes Genetics
- The Role of Dipeptide Repeats in C9ORF72-Related ALS-FTD
- (2017) Brian D. Freibaum et al. Frontiers in Molecular Neuroscience
- Current Advances and Limitations in Modeling ALS/FTD in a Dish Using Induced Pluripotent Stem Cells
- (2017) Wenting Guo et al. Frontiers in Neuroscience
- C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles
- (2016) Kyung-Ha Lee et al. CELL
- Toxic PR Poly-Dipeptides Encoded by the C9orf72 Repeat Expansion Target LC Domain Polymers
- (2016) Yi Lin et al. CELL
- C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins
- (2016) Yong-Jie Zhang et al. NATURE NEUROSCIENCE
- Transport Selectivity of Nuclear Pores, Phase Separation, and Membraneless Organelles
- (2016) H. Broder Schmidt et al. TRENDS IN BIOCHEMICAL SCIENCES
- CRISPaint allows modular base-specific gene tagging using a ligase-4-dependent mechanism
- (2016) Jonathan L. Schmid-Burgk et al. Nature Communications
- Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD
- (2016) Steven Boeynaems et al. Scientific Reports
- Nucleolar stress and impaired stress granule formation contribute to C9orf72 RAN translation-induced cytotoxicity
- (2015) Zhouteng Tao et al. HUMAN MOLECULAR GENETICS
- The C9orf72 repeat expansion disrupts nucleocytoplasmic transport
- (2015) Ke Zhang et al. NATURE
- GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport
- (2015) Brian D. Freibaum et al. NATURE
- Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS
- (2015) Ana Jovičić et al. NATURE NEUROSCIENCE
- MMEJ-assisted gene knock-in using TALENs and CRISPR-Cas9 with the PITCh systems
- (2015) Tetsushi Sakuma et al. Nature Protocols
- Nucleocytoplasmic transport under stress conditions and its role in HSP70 chaperone systems
- (2014) Shingo Kose et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Characterization of the dipeptide repeat protein in the molecular pathogenesis of c9FTD/ALS
- (2014) Mai Yamakawa et al. HUMAN MOLECULAR GENETICS
- Bidirectional transcripts of the expanded C9orf72 hexanucleotide repeat are translated into aggregating dipeptide repeat proteins
- (2013) Kohji Mori et al. ACTA NEUROPATHOLOGICA
- Cell type-specific nuclear pores: a case in point for context-dependent stoichiometry of molecular machines
- (2013) A. Ori et al. Molecular Systems Biology
- Unconventional Translation of C9ORF72 GGGGCC Expansion Generates Insoluble Polypeptides Specific to c9FTD/ALS
- (2013) Peter E.A. Ash et al. NEURON
- The C9orf72 GGGGCC Repeat Is Translated into Aggregating Dipeptide-Repeat Proteins in FTLD/ALS
- (2013) K. Mori et al. SCIENCE
- Investigating the utility of human embryonic stem cell-derived neurons to model ageing and neurodegenerative disease using whole-genome gene expression and splicing analysis
- (2012) Rickie Patani et al. JOURNAL OF NEUROCHEMISTRY
- Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study
- (2012) Elisa Majounie et al. LANCET NEUROLOGY
- Importazole, a Small Molecule Inhibitor of the Transport Receptor Importin-β
- (2011) Jonathan F. Soderholm et al. ACS Chemical Biology
- Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
- (2011) Mariely DeJesus-Hernandez et al. NEURON
- A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
- (2011) Alan E. Renton et al. NEURON
- Nuclear import by karyopherin-βs: Recognition and inhibition
- (2010) Yuh Min Chook et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration
- (2010) Agnes L. Nishimura et al. BRAIN
- Non-ATG-initiated translation directed by microsatellite expansions
- (2010) T. Zu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Age-Dependent Deterioration of Nuclear Pore Complexes Causes a Loss of Nuclear Integrity in Postmitotic Cells
- (2009) Maximiliano A. D'Angelo et al. CELL
- Characterisation of the passive permeability barrier of nuclear pore complexes
- (2009) Dagmar Mohr et al. EMBO JOURNAL
- SUnSET, a nonradioactive method to monitor protein synthesis
- (2009) Enrico K Schmidt et al. NATURE METHODS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search